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BREVIBLOC (ESMOLOL HCL)
- Supraventricular tachycardia
- Ventricular rate control in atrial fibrillation
- Perioperative hypertension
- Perioperative tachycardia
- Esmolol Iv
- Esmolol Intravenous Solution
- Esmolol In Sodium Chloride (iso-osmotic) Intravenous Soln
- Brevibloc Intravenous Solution
- Brevibloc In Sodium Chloride (iso-osmotic) Iv Solution
- By Indication
100 mg/10 mL (10 mg/mL) intravenous solution
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
esmolol 100 mg/10 mL (10 mg/mL) intravenous solution
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
esmolol 2,000 mg/100 mL (20 mg/mL) in sodium chloride (iso-osmotic) IV
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
esmolol 2,500 mg/250 mL (10 mg/mL) in sodium chloride (iso-osmotic) IV
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
100 mg/10 mL (10 mg/mL) intravenous solution
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
2,000 mg/100 mL (20 mg/mL) in sodium chloride (iso-osm) IV
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
2,500 mg/250 mL (10 mg/mL) in sodium chloride (iso-osm) IV
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
Perioperative hypertension
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
- Infuse 200 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 300 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 50 mcg/kg/minute by continuous infusion route for no more than48 hours
Perioperative tachycardia
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
- Infuse 200 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 300 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 50 mcg/kg/minute by continuous infusion route for no more than48 hours
Supraventricular tachycardia
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
- Infuse 200 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 300 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 50 mcg/kg/minute by continuous infusion route for no more than48 hours
Ventricular rate control in atrial fibrillation
- Infuse 25 mcg/kg/minute by continuous infusion route for no more than48 hours
- Infuse 200 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 300 mcg/kg/minute by continuous infusion route for no more than 48 hours
- Infuse 50 mcg/kg/minute by continuous infusion route for no more than48 hours
- None
Contraindicated
- Catapres
- Catapres-tts-1
- Catapres-tts-2
- Catapres-tts-3
- clonidine
- clonidine (PF)
- clonidine-chlorthalidone
- Clorpres
- Corlopam
- Duraclon (pf)
- fenoldopam
- fingolimod
- Gilenya
- Kapvay
Severe
Moderate
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- Anaprox
- Anaprox Ds
- Ansaid
- Caldolor
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Duexis
- Ec-naprosyn
- Feldene
- Flanax
- flurbiprofen
- hydrocodone-ibuprofen
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- Medi-profen
- Mediproxen
- meloxicam
- Midol (naproxen)
- Mobic
- Motrin Ib
- Motrin Pm
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- Neoprofen (ibuprofen Lysn)(pf)
- piroxicam
- Provil
- pseudoephedrine-ibuprofen
- Reprexain
- Sinus & Cold-d
- sulindac
- Vicoprofen
- Vimovo
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Acute asthma attack
- Acute decompensated heart failure
- Cardiogenic shock
- Heart block
- Sinus bradycardia
Contraindicated
- Pulmonary emphysema
Severe
Moderate
- Bronchospastic pulmonary disease
- Diabetes mellitus
- Kidney disease with reduction in GFR
BREVIBLOC (ESMOLOL HCL)
- Supraventricular tachycardia
- Ventricular rate control in atrial fibrillation
- Perioperative hypertension
- Perioperative tachycardia
- None
- Hypotension
More Frequent
Severe
Less Severe
- Acute confusion
- Injection site sequelae
- Peripheral ischemia
- Drowsy
- Fatigue
- Flushing
- Headache disorder
- Nausea
- Nervousness
- Pallor
- Symptoms of anxiety
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Bradycardia
- Chest pain
- Depression
- Dyspnea
- Fever
- Syncope
- Wheezing
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Esmolol
- Severity Level:
C
- Additional Notes: Reports of beta-blockade in fetus/infant; consider risk/benefit
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Esmolol Hydrochloride
Insuff data avail;Monitor for signs of b-blockade:Bradycardia,hypotension
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insuff data avail;Monitor for signs of b-blockade:Bradycardia,hypotension |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Esmolol
Cardiovascular-Minimize dose to decrease dizziness and falls. Renal-Renal elimination; use caution in starting dose and dose escalation.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
| Perioperative hypertension | |
| I97.3 | Postprocedural hypertension |
| Perioperative tachycardia | |
| R00.0 | Tachycardia, unspecified |
| Supraventricular tachycardia | |
| I47.1 | Supraventricular tachycardia |
| Ventricular rate control in atrial fibrillation | |
| I48.0 | Paroxysmal atrial fibrillation |
| I48.1 | Persistent atrial fibrillation |
| I48.11 | Longstanding persistent atrial fibrillation |
| I48.2 | Chronic atrial fibrillation |
| I48.20 | Chronic atrial fibrillation, unspecified |
| I48.21 | Permanent atrial fibrillation |
| I48.91 | Unspecified atrial fibrillation |
| 0-9 | A-Z |
|---|---|
| I47.1 | Supraventricular tachycardia |
| I48.0 | Paroxysmal atrial fibrillation |
| I48.1 | Persistent atrial fibrillation |
| I48.11 | Longstanding persistent atrial fibrillation |
| I48.2 | Chronic atrial fibrillation |
| I48.20 | Chronic atrial fibrillation, unspecified |
| I48.21 | Permanent atrial fibrillation |
| I48.91 | Unspecified atrial fibrillation |
| I97.3 | Postprocedural hypertension |
| R00.0 | Tachycardia, unspecified |
Formulary Reference Tool