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CLONIDINE (CLONIDINE)
- Hypertension
- Clonidine Weekly Transdermal Patch
- Catapres-tts-3 Transdermal Patch
- Catapres-tts-2 Transdermal Patch
- Catapres-tts-1 Transdermal Patch
- By Indication
0.1 mg/24 hr weekly transdermal patch
- Apply 1 patch by transdermal route once weekly
0.2 mg/24 hr weekly transdermal patch
- Apply 1 patch by transdermal route once weekly
0.3 mg/24 hr weekly transdermal patch
- Apply 1 patch by transdermal route once weekly
Catapres-TTS-3 0.3 mg/24 hr transdermal patch
- Apply 1 patch by transdermal route once weekly
Catapres-TTS-2 0.2 mg/24 hr transdermal patch
- Apply 1 patch by transdermal route once weekly
Catapres-TTS-1 0.1 mg/24 hr transdermal patch
- Apply 1 patch by transdermal route once weekly
Hypertension
- Apply 1 patch by transdermal route once weekly
- Apply 2 patches by transdermal route once weekly
- None
Contraindicated
- acebutolol
- atenolol
- atenolol-chlorthalidone
- Betagan
- Betapace
- Betapace Af
- betaxolol
- Betimol
- Betoptic S
- bisoprolol fumarate
- bisoprolol-hydrochlorothiazide
- Brevibloc
- Brevibloc In Nacl (iso-osm)
- brimonidine-timolol
- Bystolic
- carteolol
- carvedilol
- carvedilol phosphate
- Combigan
- Coreg
- Coreg Cr
- Corgard
- Corzide
- Cosopt
- Cosopt Pf
- dorzolamide-timolol
- dorzolamide-timolol (PF)
- Dutoprol
- esmolol
- esmolol in NaCl (iso-osm)
- Inderal La
- Inderal Xl
- Innopran Xl
- Istalol
- labetalol
- Levatol
- levobunolol
- Lopressor
- Lopressor Hct
- metipranolol
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- nadolol
- nadolol-bendroflumethiazide
- nebivolol
- penbutolol
- pindolol
- propranolol
- propranolol-hydrochlorothiazid
- Sectral
- Sorine
- sotalol
- Sotalol Af
- Tenoretic 100
- Tenoretic 50
- Tenormin
- timolol
- timolol maleate
- timolol maleate (PF)
- Timoptic
- Timoptic Ocudose (pf)
- Timoptic-xe
- Toprol Xl
- Trandate
- Zebeta
- Ziac
Severe
Moderate
- amitriptyline
- amitriptyline-chlordiazepoxide
- amoxapine
- Amrix
- Anafranil
- clomipramine
- cyclobenzaprine
- cyclobenzaprine with msm
- desipramine
- doxepin
- imipramine HCl
- imipramine pamoate
- mirtazapine
- Norpramin
- nortriptyline
- Pamelor
- perphenazine-amitriptyline
- protriptyline
- Prudoxin
- Remeron
- Remeron Soltab
- Silenor
- Surmontil
- Tabradol
- Tofranil
- Tofranil-pm
- trimipramine
- Vivactil
- Zonalon
- Magnetic resonance imaging
Contraindicated
- Atrioventricular block
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Chronic kidney disease stage 5 (failure) GFr<15 ml/min
- Depression
- Invasive surgical procedure
- Sinus bradycardia
Severe
Moderate
- Acute myocardial infarction
- Cerebrovascular disorder
- Myocardial ischemia
- Raynaud's phenomenon
CLONIDINE (CLONIDINE)
- Hypertension
- Erythema
- Pruritus of skin
- Skin inflammation
- Constipation
- Dizziness
- Drowsy
- Fatigue
- General weakness
- Xerostomia
More Frequent
Severe
Less Severe
- Body fluid retention
- Depression
- Edema
- Abnormal sexual function
- Anorexia
- Dry eye
- Erectile dysfunction
- Nausea
- Nervousness
- Ocular irritation
- Ocular itching
- Orthostatic hypotension
- Skin thickening
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Atrioventricular block
- Bradycardia
- Nightmares
- Raynaud's phenomenon
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Clonidine (Patch)
Safety and efficacy not established in adequate and well-controlled trials.
- 1 Day – 18 Years
- Safety and efficacy not established in adequate and well-controlled trials.
Clonidine Hydrochloride
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Clonidine
Potential adverse effects to infant.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Potential adverse effects to infant. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Clonidine
Cardiovascular-Risk for orthostatic hypotension, falls. Caution with conduction abnormalities. Neuro/Psych-Risk of somnolence, fatigue.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | Y | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- None
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool