Epioxa

Drug overview for EPIOXA (riboflavin 5-phosphate sodium (b2)):

Generic name: RIBOFLAVIN 5-PHOSPHATE SODIUM (B2)
Drug class: Agents for Corneal Collagen Cross-Linking
Therapeutic class: Ophthalmic Agents

Riboflavin is a water-soluble, B complex vitamin.

No enhanced Uses information available for this drug.

DRUG IMAGES

No Image Available

The following indications for EPIOXA (riboflavin 5-phosphate sodium (b2)) have been approved by the FDA:

Indications:
Corneal ectasia following refractive surgery
Progressive keratoconus

Professional Synonyms:
Corneal ectasia due to laser in situ keratomileusis
Ectatic cornea due to laser in situ keratomileusis
Ectatic cornea following refractive surgery
Unstable keratoconus

The following dosing information is available for EPIOXA (riboflavin 5-phosphate sodium (b2)):

Dosing
Administration
Dosing Information
Generic

No enhanced Dosing information available for this drug.

Riboflavin is usually administered orally. The drug may also be given by IM injection or IV infusion as a component of multivitamin injections. A parenteral formulation containing riboflavin alone is not currently commercially available.

No dosing information available.

No generic dosing information available.

The following drug interaction information is available for EPIOXA (riboflavin 5-phosphate sodium (b2)):

Contraindicated
Severe
Moderate

There are 0 contraindications.

There are 0 severe interactions.

There are 0 moderate interactions.

The following contraindication information is available for EPIOXA (riboflavin 5-phosphate sodium (b2)):

Overview
Contraindicated
Severe
Moderate

Drug contraindication overview.

No enhanced Contraindications information available for this drug.

There are 0 contraindications.

There are 2 severe contraindications. Adequate patient monitoring is recommended for safer drug use.

Severe List
Aphakia
Herpes simplex keratitis

There are 0 moderate contraindications.

The following adverse reaction information is available for EPIOXA (riboflavin 5-phosphate sodium (b2)):

Overview
Severe
Less Severe

Adverse reaction overview.

No enhanced Common Adverse Effects information available for this drug.

There are 5 severe adverse reactions.

More Frequent	Less Frequent
Corneal epithelial degeneration Corneal opacity Punctate keratitis	Vitreous detachment

Rare/Very Rare
Corneal ulcer

There are 14 less severe adverse reactions.

More Frequent	Less Frequent
Blurred vision Eye tearing Foreign body sensation of eye Ocular pain Photophobia Reduced visual acuity	Conjunctival hyperemia Corneal dystrophy Corneal edema Dry eye Headache disorder Vision impairment Visual halos

Rare/Very Rare
Descemet's membrane fold

The following precautions are available for EPIOXA (riboflavin 5-phosphate sodium (b2)):

Pediatric
Pregnant
Lactation
Geriatric

No enhanced Pediatric Use information available for this drug.

Contraindicated

None

Severe Precaution

None

Management or Monitoring Precaution

None

No enhanced Pregnancy information available for this drug.

No enhanced Lactation information available for this drug.

No enhanced Geriatric Use information available for this drug.

The following prioritized warning is available for EPIOXA (riboflavin 5-phosphate sodium (b2)):

No warning message for this drug.

The following icd codes are available for EPIOXA (riboflavin 5-phosphate sodium (b2))'s list of indications:

Corneal ectasia following refractive surgery
H18.71	Corneal ectasia
H18.711	Corneal ectasia, right eye
H18.712	Corneal ectasia, left eye
H18.713	Corneal ectasia, bilateral
H18.719	Corneal ectasia, unspecified eye
Progressive keratoconus
H18.62	Keratoconus, unstable
H18.621	Keratoconus, unstable, right eye
H18.622	Keratoconus, unstable, left eye
H18.623	Keratoconus, unstable, bilateral
H18.629	Keratoconus, unstable, unspecified eye