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FAMCICLOVIR (FAMCICLOVIR)
- Herpes zoster
- Recurrent herpes genitalis
- Recurrent herpes simplex labialis
- Recurrent mucocutaneous herpes simplex in HIV patients
- Suppression of recurrent herpes simplex infection
125 mg tablet
- 2 tablets (250 mg) by oral route 2 times per day
250 mg tablet
- 1 tablet (250 mg) by oral route every 12 hours
500 mg tablet
- 1 tablet (500 mg) by oral route every 8 hours
Herpes zoster
- 2 tablets (500 mg) by oral route every 8 hours
- 1 tablet (500 mg) by oral route every 8 hours
- 1 tablet (500 mg) by oral route every 8 hours for 7 days
- 2 tablets (500 mg) by oral route every 8 hours for 7 days
Recurrent herpes simplex labialis
- 2 tablets (250 mg) by oral route every 12 hours
- 1 tablet (250 mg) by oral route 2 times per day
- 2 tablets (250 mg) by oral route 2 times per day
- 1 tablet (250 mg) by oral route every 12 hours
Suppression of recurrent herpes simplex infection
- 2 tablets (250 mg) by oral route every 12 hours
- 1 tablet (250 mg) by oral route 2 times per day
- 2 tablets (250 mg) by oral route 2 times per day
- 1 tablet (250 mg) by oral route every 12 hours
- 1 tablet (500 mg) by oral route 2 times per day
- 1 tablet (500 mg) by oral route every 12 hours
- measles,mumps,rub,varicel(PF)
- Proquad (pf)
- varicella virus vacc live (PF)
- Varivax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- Kidney disease with reduction in GFR
Severe
Moderate
- Severe hepatic disease
FAMCICLOVIR (FAMCICLOVIR)
- Herpes zoster
- Recurrent herpes genitalis
- Recurrent herpes simplex labialis
- Recurrent mucocutaneous herpes simplex in HIV patients
- Suppression of recurrent herpes simplex infection
- None
- Diarrhea
- Headache disorder
- Nausea
More Frequent
Severe
Less Severe
- Neutropenic disorder
- Dizziness
- Dysmenorrhea
- Fatigue
- Flatulence
- Paresthesia
- Pruritus of skin
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute confusion
- Anaphylaxis
- Angioedema
- Erythema multiforme
- Hallucinations
- Hypersensitivity angiitis
- Leukopenia
- Obstructive hyperbilirubinemia
- Seizure disorder
- Skin rash
- Stevens-johnson syndrome
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
Less Severe
- Drowsy
- Migraine
- Palpitations
- Urticaria
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Famciclovir
Efficacy not established in pediatrics for chickenpox or recurrent herpes labialis. Limited data for genital herpes. Not recommended in infants for HSV suppression.
- 1 Day – 18 Years
- Efficacy not established in pediatrics for chickenpox or recurrent herpes labialis. Limited data for genital herpes. Not recommended in infants for HSV suppression.
Famciclovir
- Severity Level:
2
- Additional Notes: Insufficient human data; animal data do not sug dev tox
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Famciclovir
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Famciclovir
Renal-Adjust dose for renal impairment. Neuro/Psych-Elderly are at increased risk of CNS effects including confusion, delirium, disorientation, and hallucinations.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Herpes zoster | |
| B02 | Zoster [herpes zoster] |
| B02.0 | Zoster encephalitis |
| B02.1 | Zoster meningitis |
| B02.3 | Zoster ocular disease |
| B02.30 | Zoster ocular disease, unspecified |
| B02.31 | Zoster conjunctivitis |
| B02.32 | Zoster iridocyclitis |
| B02.33 | Zoster keratitis |
| B02.34 | Zoster scleritis |
| B02.39 | Other herpes zoster eye disease |
| B02.7 | Disseminated zoster |
| B02.8 | Zoster with other complications |
| B02.9 | Zoster without complications |
| Recurrent herpes genitalis | |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.01 | Herpesviral infection of penis |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.03 | Herpesviral cervicitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.9 | Anogenital herpesviral infection, unspecified |
| Recurrent herpes simplex labialis | |
| B00.9 | Herpesviral infection, unspecified |
| Recurrent mucocutaneous herpes simplex in HIV patients | |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.01 | Herpesviral infection of penis |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.03 | Herpesviral cervicitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.1 | Herpesviral infection of perianal skin and rectum |
| A60.9 | Anogenital herpesviral infection, unspecified |
| B00.0 | Eczema herpeticum |
| B00.1 | Herpesviral vesicular dermatitis |
| B00.2 | Herpesviral gingivostomatitis and pharyngotonsillitis |
| B00.89 | Other herpesviral infection |
| Suppression of recurrent herpes simplex infection | |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.01 | Herpesviral infection of penis |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.03 | Herpesviral cervicitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.1 | Herpesviral infection of perianal skin and rectum |
| A60.9 | Anogenital herpesviral infection, unspecified |
| B00.2 | Herpesviral gingivostomatitis and pharyngotonsillitis |
| B00.89 | Other herpesviral infection |
| B00.9 | Herpesviral infection, unspecified |
| 0-9 | A-Z |
|---|---|
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.01 | Herpesviral infection of penis |
| A60.01 | Herpesviral infection of penis |
| A60.01 | Herpesviral infection of penis |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.03 | Herpesviral cervicitis |
| A60.03 | Herpesviral cervicitis |
| A60.03 | Herpesviral cervicitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.1 | Herpesviral infection of perianal skin and rectum |
| A60.1 | Herpesviral infection of perianal skin and rectum |
| A60.9 | Anogenital herpesviral infection, unspecified |
| A60.9 | Anogenital herpesviral infection, unspecified |
| A60.9 | Anogenital herpesviral infection, unspecified |
| B00.0 | Eczema herpeticum |
| B00.1 | Herpesviral vesicular dermatitis |
| B00.2 | Herpesviral gingivostomatitis and pharyngotonsillitis |
| B00.2 | Herpesviral gingivostomatitis and pharyngotonsillitis |
| B00.89 | Other herpesviral infection |
| B00.89 | Other herpesviral infection |
| B00.9 | Herpesviral infection, unspecified |
| B00.9 | Herpesviral infection, unspecified |
| B02 | Zoster [herpes zoster] |
| B02.0 | Zoster encephalitis |
| B02.1 | Zoster meningitis |
| B02.3 | Zoster ocular disease |
| B02.30 | Zoster ocular disease, unspecified |
| B02.31 | Zoster conjunctivitis |
| B02.32 | Zoster iridocyclitis |
| B02.33 | Zoster keratitis |
| B02.34 | Zoster scleritis |
| B02.39 | Other herpes zoster eye disease |
| B02.7 | Disseminated zoster |
| B02.8 | Zoster with other complications |
| B02.9 | Zoster without complications |
Formulary Reference Tool