TENORETIC 50 (ATENOLOL/CHLORTHALIDONE)

Moderate

• acarbose

• Adalat Cc

• Advil

• Advil Allergy Sinus

• Advil Allergy-congestion Rlf

• Advil Cold & Sinus

• Advil Congestion Relief

• Advil Liqui-gel

• Advil Migraine

• Advil Pm

• Advil Pm Liqui-gels

• Afeditab Cr

• Aleve

• Aleve Cold & Sinus

• Aleve Sinus & Headache

• Aleve-d Sinus & Cold

• Aleve-d Sinus & Headache

• All Day Pain Relief

• All Day Pain Relief Sinus & Co

• All Day Relief

• Amaryl

• Anaprox

• Anaprox Ds

• Ansaid

• Apidra

• Apidra Solostar

• Calan

• Calan Sr

• Caldolor

• Cardizem

• Cardizem Cd

• Cardizem La

• Cartia Xt

• Child Ibuprofen

• Children's Advil

• Children's Ibu-drops

• Children's Ibuprofen

• Children's Medi-profen

• Children's Motrin

• Children's Profen Ib

• chlorphen-phenyleph-ibuprofen

• chlorphen-pseudoeph-ibuprofen

• cholestyramine (with sugar)

• Cholestyramine Light

• cholestyramine-aspartame

• Cold & Sinus Pain Relief

• Cold-sinus Relief

• Colestid

• Colestid Flavored

• colestipol

• dextromethorphan-quinidine

• Diabeta

• diazoxide

• Digox

• digoxin

• Dilacor Xr

• Dilt-xr

• diltiazem HCl

• Duetact

• Duexis

• Ec-naprosyn

• Feldene

• Flanax

• flurbiprofen

• glimepiride

• glipizide

• glipizide-metformin

• Glucotrol

• Glucotrol Xl

• Glucovance

• glyburide

• glyburide micronized

• glyburide-metformin

• Glynase

• Glyset

• Humalog

• Humalog Kwikpen

• Humalog Mix 50-50

• Humalog Mix 50-50 Kwikpen

• Humalog Mix 75-25

• Humalog Mix 75-25 Kwikpen

• Humulin 70/30

• Humulin N

• Humulin N Kwikpen

• Humulin R

• Humulin R U-500 "Concentrated"

• hydrocodone-ibuprofen

• I-prin

• Ibu-drops

• Ibudone

• ibuprofen

• Ibuprofen Cold

• Ibuprofen Cold-sinus(with Pse)

• Ibuprofen Ib

• Ibuprofen Jr Strength

• ibuprofen lysine (PF)

• Ibuprofen Pm

• ibuprofen-diphenhydramine

• ibuprofen-diphenhydramine HCl

• ibuprofen-famotidine

• ibuprofen-oxycodone

• ibuprofen-phenylephrine HCl

• Indocin

• indomethacin

• indomethacin sodium

• Infant's Ibuprofen

• Infant's Medi-profen

• Infant's Motrin

• Infants Ibu-drops

• Infants Profenib

• insulin asp prt-insulin aspart

• insulin aspart

• insulin detemir

• insulin glargine

• insulin glulisine

• insulin lispro

• insulin lispro protam-lispro

• insulin NPH and regular human

• insulin regular hum U-500 conc

• insulin regular human

• Lanoxin

• Lanoxin Pediatric

• Lantus

• Lantus Solostar

• Levemir

• Levemir Flexpen

• Matzim La

• Medi-profen

• Mediproxen

• mefloquine

• meloxicam

• Midol (naproxen)

• miglitol

• Minipress

• Mobic

• Motrin Ib

• Motrin Pm

• Naprelan Cr

• Naprosyn

• naproxen

• naproxen sodium

• naproxen-esomeprazole

• naproxen-pseudoephedrine

• nateglinide

• Neoprofen (ibuprofen Lysn)(pf)

• Nifedical Xl

• nifedipine

• Novolin 70/30

• Novolin N

• Novolin R

• Novolog

• Novolog Flexpen

• Novolog Mix 70-30

• Novolog Mix 70-30 Flexpen

• Novolog Penfill

• NPH insulin human recomb

• Nuedexta

• pioglitazone-glimepiride

• piroxicam

• prazosin

• Precose

• Prevalite

• Procardia

• Procardia Xl

• Proglycem

• Provil

• pseudoephedrine-ibuprofen

• Questran

• Questran Light

• quinidine gluconate

• quinidine sulfate

• Reprexain

• Sinus & Cold-d

• Starlix

• sulindac

• Tarka

• Taztia Xt

• Tiazac

• tolazamide

• tolbutamide

• trandolapril-verapamil

• verapamil

• Verelan

• Verelan Pm

• Vicoprofen

• Vimovo

• Wal-profen

• Wal-profen Cold-sinus

• Wal-proxen

Moderate

• Abnormal hepatic function tests

• Asthma

• Depression

• Gout

• Hypercalcemia

• Hypercholesterolemia

• Hyperuricemia

• Hypochloremic alkalosis

• Hypokalemia

• Hypomagnesemia

• Hyponatremia

• Psoriasis

• Raynaud's phenomenon

• Severe chronic obstructive pulmonary disease

• Sympathectomy

• Type 1 diabetes mellitus

• Type 2 diabetes mellitus

Atenolol

• Severity Level:

  1

• Additional Notes: Reports of intrauterine growth retardation

Chlorthalidone

• Severity Level:

  D

• Additional Notes: Avoid as first line treatment for hypertension during pregnancy

Contraindicated

Chlorthalidone

Mfg does not rec, minimal amnts may be excreted; may suppress lactation

General	Excretion Potential	Effect on Infant	Notes
Drug should not be given to breast feeding mothers	Excreted	Not known; no or inclusive data	Mfg does not rec, minimal amnts may be excreted; may suppress lactation

Precaution Exists

Atenolol

Monitor for bradycardia & hypotension; 1 case of bradycardia in neonate

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Drug shown to have adverse effect	Monitor for bradycardia & hypotension; 1 case of bradycardia in neonate

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Atenolol

Cardiovascular-Minimize dose to decrease dizziness and falls. Renal-Renally eliminated; use caution with starting dose and dose escalation. When used for hypertension, older adults may require an initial dose of 25 mg/day.

General-More likely to develop hypokalemia, hypomagnesemia, or hyponatremia. Cardiovascular-Elderly are more sensitive to blood pressure changes. Renal-Less effective in severe renal impairment. Endocrine-May exacerbate SIADH.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	Y	N	N	N

BEERS: N     HEDIS: N     STOPP: Y

Chlorthalidone

Cardiovascular-Minimize dose to decrease dizziness and falls. Renal-Renally eliminated; use caution with starting dose and dose escalation. When used for hypertension, older adults may require an initial dose of 25 mg/day.

General-More likely to develop hypokalemia, hypomagnesemia, or hyponatremia. Cardiovascular-Elderly are more sensitive to blood pressure changes. Renal-Less effective in severe renal impairment. Endocrine-May exacerbate SIADH.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	Y	N	N	Y

BEERS: Y     HEDIS: N     STOPP: Y

No Known Risk

None

0-9	A-Z
I10	Essential (primary) hypertension
I11	Hypertensive heart disease
I11.0	Hypertensive heart disease with heart failure
I11.9	Hypertensive heart disease without heart failure
I12	Hypertensive chronic kidney disease
I12.0	Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease
I12.9	Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13	Hypertensive heart and chronic kidney disease
I13.0	Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.1	Hypertensive heart and chronic kidney disease without heart failure
I13.10	Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.11	Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease
I13.2	Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease
I15.1	Hypertension secondary to other renal disorders