XTANDI (ENZALUTAMIDE)

Moderate

• A-hydrocort

• A-methapred

• Abilify

• Abilify Discmelt

• Abilify Maintena

• Adoxa

• alprazolam

• Alprazolam Intensol

• Anucort-hc

• Anusol-hc

• aripiprazole

• Aristospan Intra-articular

• Aristospan Intralesional

• Aromasin

• Astramorph-pf

• Ativan

• Avidoxy

• Avinza

• betamethasone acet & sod phos

• budesonide

• Buprenex

• buprenorphine

• buprenorphine-naloxone

• Butrans

• Celestone Soluspan

• Colocort

• Cortef

• Cortenema

• Cortifoam

• cortisone

• Daliresp

• Depo-medrol

• Depodur (pf)

• dexamethasone

• Dexamethasone Intensol

• dexamethasone sodium phos (PF)

• dexamethasone sodium phosphate

• Dexpak 10 Day

• Dexpak 13 Day

• Dexpak 6 Day

• Diastat

• Diastat Acudial

• diazepam

• Diazepam Intensol

• Diskets

• Dolophine

• Doryx

• Doxy-100

• doxycycline calcium

• doxycycline hyclate

• doxycycline monohydrate

• Duramorph (pf)

• Entocort Ec

• exemestane

• Ez Use Joint-tunnel-trigger

• First-duke's

• First-mary's Mouthwash

• Flo-pred

• fludrocortisone

• Grx Hicort 25

• Haldol

• Haldol Decanoate

• haloperidol

• haloperidol decanoate

• haloperidol lactate

• Hemril-30

• hydrocortisone

• hydrocortisone acetate

• hydrocortisone sod succ (PF)

• hydrocortisone sod succinate

• Kadian

• Kenalog

• lorazepam

• Lorazepam Intensol

• macitentan

• Medrol

• Medrol (pak)

• methadone

• Methadone Intensol

• Methadose

• methylprednisolone

• methylprednisolone acetate

• methylprednisolone sod suc(PF)

• methylprednisolone sodium succ

• methylprednisolone-bupivacaine

• midazolam

• midazolam (PF)

• Millipred

• Millipred Dp

• Monodox

• Morgidox

• morphine

• morphine (PF)

• morphine concentrate

• morphine liposomal (PF)

• Ms Contin

• Niravam

• nystatin-hydrocortisone-diphen

• nystatin-TCN-HC-diphenhydramin

• Opsumit

• Oracea

• Orapred

• Orapred Odt

• ospemifene

• Osphena

• Pediapred

• Physicians Ez Use M-pred

• prednisolone

• prednisolone acetate

• prednisolone sodium phosphate

• prednisone

• Prednisone Intensol

• Proctocort

• Rayos

• Rectacort-hc

• Risperdal

• Risperdal Consta

• Risperdal M-tab

• risperidone

• risperidone microspheres

• roflumilast

• Seroquel

• Solu-cortef

• Solu-cortef (pf)

• Solu-medrol

• Solu-medrol (pf)

• Suboxone

• triamcinolone acetonide

• triamcinolone hexacetonide

• triamcinolone-lidocaine

• triazolam

• Uceris

• Valium

• Veripred 20

• Vibramycin

• Xanax

• Xanax Xr

• Zubsolv

Moderate

• Myocardial ischemia

Enzalutamide

• Severity Level:

  1

• Additional Notes: Insuff human data; based on pharmacology dev tox possible; ci in preg

Contraindicated

Enzalutamide

Not indicated for use in women

General	Excretion Potential	Effect on Infant	Notes
Drug should not be given to breast feeding mothers	Unknown	Not known; no or inclusive data	Not indicated for use in women

Precaution Exists

None

General	Excretion Potential	Effect on Infant	Notes
			None

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Enzalutamide

General-In clinical trials, falls and fractures occurred in 12% and 13% of patients. Median time to onset of fracture was 336 days. Evaluate fracture and fall risk. Gastrointestinal-May worsen existing constipation; evaluate bowel regimen.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	N	N	N	N	N	N

BEERS: N     HEDIS: N     STOPP: N

No Known Risk

None

0-9	A-Z
C61	Malignant neoplasm of prostate
C61	Malignant neoplasm of prostate