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GLIADEL (CARMUSTINE IN POLIFEPROSAN 20)
- Glioblastoma multiforme
- Malignant glioma
7.7 mg implant
- Insert 8 wafers (61.6 mg) by intracavity route once
Wafer 7.7 mg implant
- Insert 8 wafers (61.6 mg) by intracavity route once
Glioblastoma multiforme
- Insert 5 wafers (38.5 mg) by intracavity route once
- Insert 6 wafers (46.2 mg) by intracavity route once
- Insert 7 wafers (53.9 mg) by intracavity route once
- Insert 8 wafers (61.6 mg) by intracavity route once
Malignant glioma
- Insert 5 wafers (38.5 mg) by intracavity route once
- Insert 6 wafers (46.2 mg) by intracavity route once
- Insert 7 wafers (53.9 mg) by intracavity route once
- Insert 8 wafers (61.6 mg) by intracavity route once
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- BCG vaccine, live (PF)
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- typhoid vaccine
- Tysabri
- varicella virus vacc live (PF)
- Varivax (pf)
- Vivotif Berna Vaccine
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- cimetidine
- clozapine
- Clozaril
- deferiprone
- Fazaclo
- Ferriprox
- Heartburn Relief
- Tagamet Hb
- Versacloz
Severe
Moderate
- Cerebyx
- Digox
- digoxin
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- ethotoin
- fosphenytoin
- Lanoxin
- Peganone
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Lactating mother
Contraindicated
- Brain abscess
- Cerebral edema
- Intracranial hypertension
- Meningitis
- Obstructive hydrocephalus
- Pregnancy
- Seizure disorder
Severe
Moderate
- None
GLIADEL (CARMUSTINE IN POLIFEPROSAN 20)
- Glioblastoma multiforme
- Malignant glioma
- Cerebral edema
- Tonic clonic seizure
- Urinary tract infection
- Constipation
- Depression
- Fever
- General weakness
- Impaired wound healing
- Nausea
- Treatment site sequelae
- Vomiting
More Frequent
Severe
Less Severe
- Brain abscess
- Intracranial hypertension
- Meningitis
- Acute abdominal pain
- Back pain
- Chest pain
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Hepatic veno-occlusive disease
- Severe headache disorder
Less Severe
- None
Contraindicated
None
Severe Precaution
Carmustine (wafer)
No safety and efficacy established in pediatrics.
- 1 Day – 18 Years
- No safety and efficacy established in pediatrics.
Management or Monitoring Precaution
None
Carmustine
- Severity Level:
D
- Additional Notes: Based on drug pharmacology developmental toxicity is possible.
Contraindicated
Carmustine
Potential serious adv eff on infant;Moleculr wt low enough for poss excretion
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Potential serious adv eff on infant;Moleculr wt low enough for poss excretion |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Glioblastoma multiforme | |
| C71 | Malignant neoplasm of brain |
| C71.0 | Malignant neoplasm of cerebrum, except lobes and ventricles |
| C71.1 | Malignant neoplasm of frontal lobe |
| C71.2 | Malignant neoplasm of temporal lobe |
| C71.3 | Malignant neoplasm of parietal lobe |
| C71.4 | Malignant neoplasm of occipital lobe |
| C71.5 | Malignant neoplasm of cerebral ventricle |
| C71.6 | Malignant neoplasm of cerebellum |
| C71.7 | Malignant neoplasm of brain stem |
| C71.8 | Malignant neoplasm of overlapping sites of brain |
| C71.9 | Malignant neoplasm of brain, unspecified |
| Malignant glioma | |
| C71.9 | Malignant neoplasm of brain, unspecified |
| D43.2 | Neoplasm of uncertain behavior of brain, unspecified |
| 0-9 | A-Z |
|---|---|
| C71 | Malignant neoplasm of brain |
| C71.0 | Malignant neoplasm of cerebrum, except lobes and ventricles |
| C71.1 | Malignant neoplasm of frontal lobe |
| C71.2 | Malignant neoplasm of temporal lobe |
| C71.3 | Malignant neoplasm of parietal lobe |
| C71.4 | Malignant neoplasm of occipital lobe |
| C71.5 | Malignant neoplasm of cerebral ventricle |
| C71.6 | Malignant neoplasm of cerebellum |
| C71.7 | Malignant neoplasm of brain stem |
| C71.8 | Malignant neoplasm of overlapping sites of brain |
| C71.9 | Malignant neoplasm of brain, unspecified |
| C71.9 | Malignant neoplasm of brain, unspecified |
| D43.2 | Neoplasm of uncertain behavior of brain, unspecified |
Formulary Reference Tool