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CHLORAMPHENICOL SOD SUCCINATE (CHLORAMPHENICOL NA SUCC)
- Bacteroides brain abscess
- Boutonneuse fever
- H. influenzae meningitis
- Meningococcal meningitis
- Paratyphoid fever
- Rickettsial infection
- Streptococcal meningitis
- Typhoid fever
- Chloramphenicol Sodium Succinate Intravenous Solution
- Chloramphenicol Sod Succinate Intravenous Solution
- By Indication
chloramphenicol sodium succinate 1 gram intravenous solution
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
chloramphenicol sodium succinate 1 gram intravenous solution
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
Bacteroides brain abscess
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
Boutonneuse fever
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
H. influenzae meningitis
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
Meningococcal meningitis
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
Paratyphoid fever
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
Rickettsial infection
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
Streptococcal meningitis
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
Typhoid fever
- Inject 12.5 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- Inject 25 mg/kg over at least 1 minute(s) by intravenous route every 6 hours
- typhoid vaccine
- Vivotif Berna Vaccine
Contraindicated
- Altavera (28)
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- Apri
- Aranelle (28)
- Aubra
- Aviane
- Azurette (28)
- Balziva (28)
- Beyaz
- Brevicon (28)
- Briellyn
- Camila
- Camrese
- Camrese Lo
- Caziant (28)
- Chateal
- citalopram
- Coumadin
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- Depo-provera
- Depo-subq Provera 104
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- drospirenone-e.estradiol-lm.FA
- drospirenone-ethinyl estradiol
- Elinest
- Emoquette
- Enpresse
- Enskyce
- Errin
- Estarylla
- estradiol valerate-dienogest
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- Falmina (28)
- Femcon Fe
- Generess Fe
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- Heather
- Introvale
- Jantoven
- Jencycla
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kariva (28)
- Kelnor 1/35 (28)
- Kurvelo
- L norgest&E estradiol-E estrad
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- medroxyprogesterone
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Minastrin 24 Fe
- Mircette (28)
- Mirena
- Modicon (28)
- Mono-linyah
- Mononessa (28)
- My Way
- Myzilra
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- Nexplanon
- Next Choice One Dose
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Nuvaring
- Ocella
- Ogestrel (28)
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- Philith
- Pimtrea (28)
- Pirmella
- Plan B One-step
- Portia
- Previfem
- Quartette
- Quasense
- Reclipsen (28)
- Safyral
- Seasonique
- Sprintec (28)
- Sronyx
- Syeda
- Tilia Fe
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- Trinessa (28)
- Trivora (28)
- Velivet Triphasic Regimen (28)
- Vestura (28)
- Viorele (28)
- Vyfemla (28)
- warfarin
- Wera (28)
- Wymzya Fe
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- Anti-diarrhea
- Anti-diarrheal (lope)-anti-gas
- Anti-diarrheal (loperamide)
- Celexa
- Cerebyx
- Diamode
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- ethotoin
- fosphenytoin
- Imodium Multi-symptom Relief
- Lo-peramide
- loperamide
- loperamide-simethicone
- Peganone
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- rivaroxaban
- tolbutamide
- Ultra A-d
- Xarelto
- Hemolytic anemia from PK and g6PD deficiencies
- Lactating mother
Contraindicated
- Acute intermittent porphyria
- Aplastic anemia
- Bone marrow depression
- Granulocytopenic disorder
- Hemorrhage
- Hypoplastic anemia
- Kidney disease with reduction in GFR
- Optic neuritis
- Paroxysmal nocturnal hemoglobinuria
- Peripheral neuropathy
- Thrombocytopenic disorder
Severe
Moderate
- Anemia
- Disease of liver
CHLORAMPHENICOL SOD SUCCINATE (CHLORAMPHENICOL NA SUCC)
- Bacteroides brain abscess
- Boutonneuse fever
- H. influenzae meningitis
- Meningococcal meningitis
- Paratyphoid fever
- Rickettsial infection
- Streptococcal meningitis
- Typhoid fever
- None
- None
More Frequent
Severe
Less Severe
- Blood dyscrasias
- Granulocytopenic disorder
- Thrombocytopenic disorder
- Diarrhea
- Gastrointestinal irritation
- Nausea
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Allergic dermatitis
- Anaphylaxis
- Angioedema
- Aplastic anemia
- Dyspnea
- Enterocolitis
- Gray syndrome from chloramphenicol administration
- Leukopenia
- Maculopapular rash
- Optic neuritis
- Paresthesia
- Paroxysmal nocturnal hemoglobinuria
- Urticaria
Less Severe
- Acute confusion
- Delirium
- Depression
- Erythema
- Fever
- Glossitis
- Headache disorder
- Peripheral neuritis
- Skin rash
- Stomatitis
Contraindicated
None
Severe Precaution
Chloramphenicol (Systemic)
Gray syndrome risk in neonates and premature infants with immature metabolic function. Monitoring recommended.
- 1 Day – 29 Days
- Gray syndrome risk in neonates and premature infants with immature metabolic function. Monitoring recommended.
Management or Monitoring Precaution
None
Chloramphenicol
- Severity Level:
C
- Additional Notes:
Contraindicated
Chloramphenicol
Possible idiosyncratic bone marrow suppression.
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Excreted | Drug shown to have adverse effect | Possible idiosyncratic bone marrow suppression. |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Chloramphenicol
Renal-Clearance may be affected in renally impaired elderly. Monitor plasma levels every 2 days.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Bacteroides brain abscess | |
| B96.6 | Bacteroides fragilis [b. fragilis] as the cause of diseases classified elsewhere |
| Boutonneuse fever | |
| A77.1 | Spotted fever due to rickettsia conorii |
| H. influenzae meningitis | |
| G00.0 | Hemophilus meningitis |
| Meningococcal meningitis | |
| A39.0 | Meningococcal meningitis |
| Paratyphoid fever | |
| A01.1 | Paratyphoid fever A |
| A01.2 | Paratyphoid fever B |
| A01.3 | Paratyphoid fever C |
| A01.4 | Paratyphoid fever, unspecified |
| Rickettsial infection | |
| A75 | Typhus fever |
| A75.0 | Epidemic louse-borne typhus fever due to rickettsia prowazekii |
| A75.1 | Recrudescent typhus [brill's disease] |
| A75.2 | Typhus fever due to rickettsia typhi |
| A75.3 | Typhus fever due to rickettsia tsutsugamushi |
| A75.9 | Typhus fever, unspecified |
| A77 | Spotted fever [tick-borne rickettsioses] |
| A77.0 | Spotted fever due to rickettsia rickettsii |
| A77.1 | Spotted fever due to rickettsia conorii |
| A77.2 | Spotted fever due to rickettsia siberica |
| A77.3 | Spotted fever due to rickettsia australis |
| A77.8 | Other spotted fevers |
| A77.9 | Spotted fever, unspecified |
| A79 | Other rickettsioses |
| A79.0 | Trench fever |
| A79.1 | Rickettsialpox due to rickettsia akari |
| A79.8 | Other specified rickettsioses |
| A79.81 | Rickettsiosis due to ehrlichia sennetsu |
| A79.89 | Other specified rickettsioses |
| A79.9 | Rickettsiosis, unspecified |
| Streptococcal meningitis | |
| G00.1 | Pneumococcal meningitis |
| G00.2 | Streptococcal meningitis |
| Typhoid fever | |
| A01.0 | Typhoid fever |
| A01.00 | Typhoid fever, unspecified |
| A01.01 | Typhoid meningitis |
| A01.02 | Typhoid fever with heart involvement |
| A01.03 | Typhoid pneumonia |
| A01.04 | Typhoid arthritis |
| A01.05 | Typhoid osteomyelitis |
| A01.09 | Typhoid fever with other complications |
| 0-9 | A-Z |
|---|---|
| A01.0 | Typhoid fever |
| A01.00 | Typhoid fever, unspecified |
| A01.01 | Typhoid meningitis |
| A01.02 | Typhoid fever with heart involvement |
| A01.03 | Typhoid pneumonia |
| A01.04 | Typhoid arthritis |
| A01.05 | Typhoid osteomyelitis |
| A01.09 | Typhoid fever with other complications |
| A01.1 | Paratyphoid fever A |
| A01.2 | Paratyphoid fever B |
| A01.3 | Paratyphoid fever C |
| A01.4 | Paratyphoid fever, unspecified |
| A39.0 | Meningococcal meningitis |
| A75 | Typhus fever |
| A75.0 | Epidemic louse-borne typhus fever due to rickettsia prowazekii |
| A75.1 | Recrudescent typhus [brill's disease] |
| A75.2 | Typhus fever due to rickettsia typhi |
| A75.3 | Typhus fever due to rickettsia tsutsugamushi |
| A75.9 | Typhus fever, unspecified |
| A77 | Spotted fever [tick-borne rickettsioses] |
| A77.0 | Spotted fever due to rickettsia rickettsii |
| A77.1 | Spotted fever due to rickettsia conorii |
| A77.1 | Spotted fever due to rickettsia conorii |
| A77.2 | Spotted fever due to rickettsia siberica |
| A77.3 | Spotted fever due to rickettsia australis |
| A77.8 | Other spotted fevers |
| A77.9 | Spotted fever, unspecified |
| A79 | Other rickettsioses |
| A79.0 | Trench fever |
| A79.1 | Rickettsialpox due to rickettsia akari |
| A79.8 | Other specified rickettsioses |
| A79.81 | Rickettsiosis due to ehrlichia sennetsu |
| A79.89 | Other specified rickettsioses |
| A79.9 | Rickettsiosis, unspecified |
| B96.6 | Bacteroides fragilis [b. fragilis] as the cause of diseases classified elsewhere |
| G00.0 | Hemophilus meningitis |
| G00.1 | Pneumococcal meningitis |
| G00.2 | Streptococcal meningitis |
Formulary Reference Tool