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NPLATE (ROMIPLOSTIM)
- Severe thrombocytopenia in refractory chronic ITP
125 mcg subcutaneous solution
- Inject 1 mcg/kg by subcutaneous route once weekly
250 mcg subcutaneous solution
- Inject 1 mcg/kg by subcutaneous route once weekly
500 mcg subcutaneous solution
- Inject 1 mcg/kg by subcutaneous route once weekly
Severe thrombocytopenia in refractory chronic ITP
- Inject 1 mcg/kg by subcutaneous route once weekly
- Inject 10 mcg/kg by subcutaneous route once weekly
- Inject 2 mcg/kg by subcutaneous route once weekly
- None
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- Myelodysplastic syndrome
- Thromboembolic disorder
Severe
Moderate
- Increased reticulin bone marrow deposition
- Thrombocytosis
NPLATE (ROMIPLOSTIM)
- Severe thrombocytopenia in refractory chronic ITP
- None
- Acute abdominal pain
- Arthralgias
- Dizziness
- Dyspepsia
- Insomnia
- Myalgias
- Paresthesia
- Shoulder pain
- Upper respiratory infection
More Frequent
Severe
Less Severe
- Increased reticulin bone marrow deposition
- Diarrhea
- Headache disorder
- Limb pain
- Pain in oropharynx
- Peripheral edema
- Purpura
- Skin rash
- Urticaria
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Angioedema
- Erythromelalgia
- Hypersensitivity drug reaction
- Portal vein thrombosis
- Thromboembolic disorder
- Thrombotic disorder
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Romiplostim
Safety and efficacy not established in pediatric patients <1 year
- 1 Day – 364 Days
- Safety and efficacy not established in pediatric patients <1 year
Romiplostim
- Severity Level:
2
- Additional Notes: Insufficient human data; crossed placenta in rats and caused thrombocytosis.
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Romiplostim
Insufficient data available
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
Severe thrombocytopenia in refractory chronic ITP | |
D69.3 | Immune thrombocytopenic purpura |
0-9 | A-Z |
---|---|
D69.3 | Immune thrombocytopenic purpura |
Formulary Reference Tool