ARANESP (DARBEPOETIN ALFA IN POLYSORBATE 80)
- Anemia due to chemotherapy and radiotherapy combination
- Anemia in chronic kidney disease
- Chemotherapy-induced anemia
- Aranesp (in Polysorbate) Injection Syringe
- Aranesp (in Polysorbate) Injection Solution
- By Indication
10 mcg/0.4 mL (in polysorbate) injection syringe
- Dosage information is not available
100 mcg/0.5 mL (in polysorbate) injection syringe
- Dosage information is not available
150 mcg/0.3 mL (in polysorbate) injection syringe
- Dosage information is not available
200 mcg/0.4 mL (in polysorbate) injection syringe
- Dosage information is not available
25 mcg/0.42 mL (in polysorbate) injection syringe
- Dosage information is not available
300 mcg/0.6 mL (in polysorbate) injection syringe
- Dosage information is not available
40 mcg/0.4 mL (in polysorbate) injection syringe
- Dosage information is not available
500 mcg/mL (in polysorbate) injection syringe
- Inject 1 milliliter (500 mcg) by subcutaneous route every 3 weeks in the abdomen, thigh, upper buttocks, or outer upper arm (rotate site)
60 mcg/0.3 mL (in polysorbate) injection syringe
- Dosage information is not available
100 mcg/mL (in polysorbate) Injection
- Dosage information is not available
150 mcg/0.75 mL (in polysorbate) Injection
- Dosage information is not available
200 mcg/mL (in polysorbate) Injection
- Dosage information is not available
25 mcg/mL (in polysorbate) Injection
- Dosage information is not available
300 mcg/mL (in polysorbate) Injection
- Dosage information is not available
40 mcg/mL (in polysorbate) Injection
- Dosage information is not available
60 mcg/mL (in polysorbate) Injection
- Dosage information is not available
Anemia due to chemotherapy and radiotherapy combination
- Inject 2.25 mcg/kg by subcutaneous route once weekly in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 500 mcg by subcutaneous route every 3 weeks in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 2.25 mcg/kg by subcutaneous route once weekly
- Inject 500 mcg by subcutaneous route every 3 weeks
- Inject 1 milliliter (500 mcg) by subcutaneous route every 3 weeks in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 1 milliliter (500 mcg) by subcutaneous route every 3 weeks in the abdomen, thigh, upper buttocks, or outer upper arm (rotate site)
Anemia in chronic kidney disease
- Inject 0.45 mcg/kg by intravenous route every 4 weeks
- Inject 0.45 mcg/kg by subcutaneous route every 4 weeks in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 0.45 mcg/kg by subcutaneous route once weekly in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Infuse 0.45 mcg/kg by intravenous route once weekly
- Inject 0.75 mcg/kg by intravenous route every 2 weeks
- Inject 0.75 mcg/kg by subcutaneous route every 2 weeks in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 1 milliliter (140 mg) by subcutaneous route every 2 weeks in the abdomen, thigh, or outer area of upper arm (rotate sites)
Chemotherapy-induced anemia
- Inject 2.25 mcg/kg by subcutaneous route once weekly in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 500 mcg by subcutaneous route every 3 weeks in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 2.25 mcg/kg by subcutaneous route once weekly
- Inject 500 mcg by subcutaneous route every 3 weeks
- Inject 1 milliliter (500 mcg) by subcutaneous route every 3 weeks in the abdomen, thighs, upper outer areas of buttocks, or outer area of upper arms rotating injection sites
- Inject 1 milliliter (500 mcg) by subcutaneous route every 3 weeks in the abdomen, thigh, upper buttocks, or outer upper arm (rotate site)
- None
Contraindicated
- None
Severe
Moderate
- None
- Pure red cell aplasia
- Severe uncontrolled hypertension
Contraindicated
- Acute decompensated heart failure
- Acute myocardial infarction
- Cerebrovascular accident
- Deep venous thrombosis
- Pulmonary thromboembolism
- Seizure disorder
- Thromboembolic disorder
- Thrombotic disorder
- Vascular access thrombosis
- Vitamin b12 deficiency
Severe
Moderate
- Edema
- Folate deficiency
- Hypertension
- Iron deficiency anemia
- Porphyria
ARANESP (DARBEPOETIN ALFA IN POLYSORBATE 80)
- Anemia due to chemotherapy and radiotherapy combination
- Anemia in chronic kidney disease
- Chemotherapy-induced anemia
- Chronic heart failure
- Dyspnea
- Hypertension
- Thrombotic disorder
- Cough
- Edema
- Injection site sequelae
- Limb pain
- Peripheral edema
More Frequent
Severe
Less Severe
- Acute myocardial infarction
- Angina
- Cerebrovascular accident
- Hypotension
- Pulmonary thromboembolism
- Seizure disorder
- Thromboembolic disorder
- Transient cerebral ischemia
- Vascular access thrombosis
- Acute abdominal pain
- Erythema
- Hypervolemia
- Skin rash
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Angioedema
- Bronchospastic pulmonary disease
- Deep venous thrombosis
- Erythema multiforme
- Exfoliative dermatitis
- Hypertensive crisis
- Pure red cell aplasia
- Shortened time to tumor progression
- Stevens-johnson syndrome
- Toxic epidermal necrolysis
- Urticaria
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Darbepoetin Alfa
- Severity Level:
2
- Additional Notes: Insufficient human data available. increases post-implantation loss in animals.
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Darbepoetin Alfa
Insufficient data available
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Discuss the risks and benefits of darbepoetin alfa with your doctor, as this medication may rarely cause very serious (possibly fatal) side effects, including blood clots, heart attack, stroke, or heart failure. It is very important to keep all lab appointments since your doctor will need to carefully check your red blood cell count and hemoglobin level. The lowest effective dose of this medication should be used.<br /><br /> When used to treat anemia related to cancer, darbepoetin alfa may also increase the risk of death and/or cause your tumor to grow faster. This medication should be stopped after completing a treatment course of chemotherapy as directed by your doctor.
Anemia due to chemotherapy and radiotherapy combination | |
D64.81 | Anemia due to antineoplastic chemotherapy |
Z51.0 | Encounter for antineoplastic radiation therapy |
Anemia in chronic kidney disease | |
D63.1 | Anemia in chronic kidney disease |
N18.4 | Chronic kidney disease, stage 4 (severe) |
N18.5 | Chronic kidney disease, stage 5 |
N18.6 | End stage renal disease |
Z99.2 | Dependence on renal dialysis |
Chemotherapy-induced anemia | |
D64.81 | Anemia due to antineoplastic chemotherapy |
0-9 | A-Z |
---|---|
D63.1 | Anemia in chronic kidney disease |
D64.81 | Anemia due to antineoplastic chemotherapy |
D64.81 | Anemia due to antineoplastic chemotherapy |
N18.4 | Chronic kidney disease, stage 4 (severe) |
N18.5 | Chronic kidney disease, stage 5 |
N18.6 | End stage renal disease |
Z51.0 | Encounter for antineoplastic radiation therapy |
Z99.2 | Dependence on renal dialysis |