ALTIPRES-B (brompheniramine maleate/phenylephrine HCl/dextromethorphan)
- cold symptoms
- cough
- inflammation of the nose due to an allergy
- runny nose
- stuffy nose
- vasomotor rhinitis
- Tussi Pres-b Oral Liquid
- Presgen B Oral Liquid
- Glenmax Peb Dm Forte Oral Liquid
- Brompheniramine-phenylephrine-dm Oral Liquid
- Altipres-b Oral Liquid
- By Indication
4 mg-10 mg-20 mg/5 mL oral liquid
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
4 mg-10 mg-30 mg/5 mL oral liquid
- Dosage information is not available
Tussi Pres-B 4 mg-10 mg-20 mg/5 mL oral liquid
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
Tussi Pres-B 4 mg-10 mg-30 mg/5 mL oral liquid
- Dosage information is not available
4 mg-10 mg-20 mg/5 mL oral liquid
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
4 mg-10 mg-20 mg/5 mL oral liquid
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
brompheniramine-phenylephrine-DM 2 mg-5 mg-10 mg/5 mL oral liquid
- 10 milliliters by oral route every 4 hours as needed
brompheniramine-phenylephrine-DM 4 mg-10 mg-20 mg/5 mL oral liquid
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
brompheniramine-phenylephrine-DM 4 mg-10 mg-30 mg/5 mL oral liquid
- Dosage information is not available
brompheniramine-phenylephrine-DM 4 mg-7.5 mg-15 mg/5 mL oral liquid
- 5 milliliters by oral route every 4-6 hours
4 mg-10 mg-20 mg/5 mL oral liquid
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
Allergic rhinitis
- 5 milliliters by oral route every 4 hours as needed
- 5 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 6 hours
- 5 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 6 hours as needed
- 5 milliliters by oral route every 4 hours
- 10 milliliters by oral route every 4 hours as needed, not to exceed 40 ml in 24Hrs
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
- 5 milliliters by oral route every 4-6 hours as needed
- 10 milliliters by oral route every 4 hours not to exceed 40Ml in24Hrs
Cold symptoms
- 5 milliliters by oral route every 4 hours as needed
- 5 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 6 hours
- 5 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 6 hours as needed
- 5 milliliters by oral route every 4 hours
- 10 milliliters by oral route every 4 hours as needed, not to exceed 40 ml in 24Hrs
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
- 5 milliliters by oral route every 4-6 hours as needed
- 10 milliliters by oral route every 4 hours not to exceed 40Ml in24Hrs
Cough
- 5 milliliters by oral route every 4 hours as needed
- 5 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 6 hours
- 5 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 6 hours as needed
- 5 milliliters by oral route every 4 hours
- 10 milliliters by oral route every 4 hours as needed, not to exceed 40 ml in 24Hrs
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
- 5 milliliters by oral route every 4-6 hours as needed
- 10 milliliters by oral route every 4 hours not to exceed 40Ml in24Hrs
Nasal congestion
- 5 milliliters by oral route every 4 hours as needed
- 5 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 6 hours
- 5 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 6 hours as needed
- 5 milliliters by oral route every 4 hours
- 10 milliliters by oral route every 4 hours as needed, not to exceed 40 ml in 24Hrs
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
- 5 milliliters by oral route every 4-6 hours as needed
- 10 milliliters by oral route every 4 hours not to exceed 40Ml in24Hrs
Rhinorrhea
- 5 milliliters by oral route every 4 hours as needed
- 5 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 6 hours
- 5 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 6 hours as needed
- 5 milliliters by oral route every 4 hours
- 10 milliliters by oral route every 4 hours as needed, not to exceed 40 ml in 24Hrs
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
- 5 milliliters by oral route every 4-6 hours as needed
- 10 milliliters by oral route every 4 hours not to exceed 40Ml in24Hrs
Vasomotor rhinitis
- 5 milliliters by oral route every 4 hours as needed
- 5 milliliters by oral route every 6 hours as needed
- 10 milliliters by oral route every 6 hours
- 5 milliliters by oral route every 6 hours
- 10 milliliters by oral route every 6 hours as needed
- 5 milliliters by oral route every 4 hours
- 10 milliliters by oral route every 4 hours as needed, not to exceed 40 ml in 24Hrs
- 10 milliliters by oral route every 4-6 hours as needed, not to exceed 40 ml in 24Hrs
- 5 milliliters by oral route every 4-6 hours as needed
- 10 milliliters by oral route every 4 hours not to exceed 40Ml in24Hrs
- Azilect
- Eldepryl
- isocarboxazid
- linezolid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- rasagiline
- selegiline HCl
- tranylcypromine
- Zelapar
- Zyvox
Contraindicated
- bromocriptine
- cabergoline
- Cafergot
- Compound 347
- Cycloset
- D.h.e.45
- dihydroergotamine
- enflurane
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- Forane
- isoflurane
- K-tab
- Klor-con
- Klor-con 10
- Klor-con M10
- Klor-con M15
- Klor-con M20
- Medi-lyte
- methylergonovine
- Migergot
- Migranal
- Parlodel
- potassium chloride
- potassium citrate
- potassium Cl-calcium phos-mag
- sevoflurane
- sodium Cl-potassium chloride
- Sojourn
- Terrell
- Thermotabs
- Ultane
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
Severe
Moderate
- methyldopa
- methyldopa-hydrochlorothiazide
- methyldopate
- reserpine
- Severe uncontrolled hypertension
Contraindicated
- Angle-closure glaucoma
- Benign prostatic hyperplasia
- Bladder outflow obstruction
- Chronic idiopathic constipation
- Coronary artery disease
- Hypertension
- Hyperthyroidism
- Stenosing peptic ulcer
- Systemic mastocytosis
- Urinary retention
Severe
Moderate
- Chronic heart failure
- Hypertension
- Hyperthyroidism
- Ocular hypertension
ALTIPRES-B (brompheniramine maleate/phenylephrine HCl/dextromethorphan)
- cold symptoms
- cough
- inflammation of the nose due to an allergy
- runny nose
- stuffy nose
- vasomotor rhinitis
- None
- Dizziness
- Drowsy
- Thick bronchial secretions
More Frequent
Severe
Less Severe
- None
- Sedation
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Blood dyscrasias
- Cardiac arrhythmia
- Dizziness
- Extrasystoles
- Hallucinations
- Headache disorder
- Hemolytic anemia
- Hyperhidrosis
- Hypersensitivity drug reaction
- Hypotension
- Insomnia
- Nervousness
- Pallor
- Seizure disorder
- Tachycardia
- Tremor
- Vomiting
Less Severe
- Abdominal distension
- Abdominal pain with cramps
- Acute abdominal pain
- Acute confusion
- Anorexia
- Anticholinergic toxicity
- Ataxia
- Blurred vision
- Chest discomfort
- Chills
- Constipation
- Diarrhea
- Diplopia
- Dizziness
- Drowsy
- Dry nose
- Dry throat
- Dyspnea
- Dysuria
- Euphoria
- Excitement
- Fatigue
- Headache disorder
- Hyperhidrosis
- Increased urinary frequency
- Insomnia
- Irritability
- Maculopapular rash
- Malaise
- Migraine
- Nausea
- Nervousness
- Nightmares
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin photosensitivity
- Skin rash
- Symptoms of anxiety
- Tachycardia
- Tinnitus
- Tremor
- Urinary retention
- Urticaria
- Vertigo
- Visual changes
- Vomiting
- Wheezing
- Xerostomia
Contraindicated
Brompheniramine
Possible CNS excitation, convulsions in newborns.
Risk of serious and life-threatening adverse effects of CNS depression or excitation. Not recommended age <2 years. Avoid using with underlying asthma.
Do not use in pediatrics <6 years of age unless clinician consultation.
Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 1 Day – 29 Days
- 1 Possible CNS excitation, convulsions in newborns.
- 1 Risk of serious and life-threatening adverse effects of CNS depression or excitation. Not recommended age <2 years. Avoid using with underlying asthma.
- 30 Days – 2 Years
- 1 Possible CNS excitation, convulsions in newborns.
- 1 Risk of serious and life-threatening adverse effects of CNS depression or excitation. Not recommended age <2 years. Avoid using with underlying asthma.
- 1 Day – 6 Years
- 1 Possible CNS excitation, convulsions in newborns.
- 1 Risk of serious and life-threatening adverse effects of CNS depression or excitation. Not recommended age <2 years. Avoid using with underlying asthma.
Dextromethorphan (OTC, Select)
Possible CNS excitation, convulsions in newborns.
Risk of serious and life-threatening adverse effects of CNS depression or excitation. Not recommended age <2 years. Avoid using with underlying asthma.
Do not use in pediatrics <6 years of age unless clinician consultation.
Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 1 Day – 29 Days
- 1 Do not use in pediatrics <6 years of age unless clinician consultation.
- 30 Days – 2 Years
- 1 Do not use in pediatrics <6 years of age unless clinician consultation.
- 1 Day – 6 Years
- 1 Do not use in pediatrics <6 years of age unless clinician consultation.
Phenylephrine (oral)
Possible CNS excitation, convulsions in newborns.
Risk of serious and life-threatening adverse effects of CNS depression or excitation. Not recommended age <2 years. Avoid using with underlying asthma.
Do not use in pediatrics <6 years of age unless clinician consultation.
Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 1 Day – 29 Days
- 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 30 Days – 2 Years
- 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 1 Day – 6 Years
- 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
Severe Precaution
Brompheniramine
Risk of CNS excitation and respiratory depression. Avoid using with underlying asthma. Consult healthcare provider.
- 2 Years – 6 Years
- Risk of CNS excitation and respiratory depression. Avoid using with underlying asthma. Consult healthcare provider.
Management or Monitoring Precaution
None
Brompheniramine
- Severity Level:
2
- Additional Notes: Low risk, premature infant at risk of retrolental fibroplasia
Dextromethorphan
- Severity Level:
2
- Additional Notes: Available human data show no increased risk for major birth defects
Phenylephrine
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Brompheniramine
Not recommended. may cause paradoxical excitation/inhibit lactation.
Insufficient data available; molecular wt low enough for possible excretion
Oral bioavailability low; infant exposure may be minimal
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Not recommended. may cause paradoxical excitation/inhibit lactation. |
Dextromethorphan
Not recommended. may cause paradoxical excitation/inhibit lactation.
Insufficient data available; molecular wt low enough for possible excretion
Oral bioavailability low; infant exposure may be minimal
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available; molecular wt low enough for possible excretion |
Phenylephrine
Not recommended. may cause paradoxical excitation/inhibit lactation.
Insufficient data available; molecular wt low enough for possible excretion
Oral bioavailability low; infant exposure may be minimal
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Not known; no or inclusive data | Oral bioavailability low; infant exposure may be minimal |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Brompheniramine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
Phenylephrine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
Allergic rhinitis | |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
Cold symptoms | |
J00 | Acute nasopharyngitis [common cold] |
Cough | |
R05 | Cough |
R05.1 | Acute cough |
R05.2 | Subacute cough |
R05.3 | Chronic cough |
R05.9 | Cough, unspecified |
Nasal congestion | |
R09.81 | Nasal congestion |
Rhinorrhea | |
R09.82 | Postnasal drip |
Vasomotor rhinitis | |
J30.0 | Vasomotor rhinitis |
0-9 | A-Z |
---|---|
J00 | Acute nasopharyngitis [common cold] |
J30.0 | Vasomotor rhinitis |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
R05 | Cough |
R05.1 | Acute cough |
R05.2 | Subacute cough |
R05.3 | Chronic cough |
R05.9 | Cough, unspecified |
R09.81 | Nasal congestion |
R09.82 | Postnasal drip |