ALTIPRES-B (brompheniramine maleate/phenylephrine hcl/dextromethorphan)


Drug overview for ALTIPRES-B (brompheniramine maleate/phenylephrine hcl/dextromethorphan):

Generic name: brompheniramine maleate/phenylephrine HCl/dextromethorphan
Drug class: Amphetamines/Anorexiants/Stimulants
Therapeutic class: Respiratory Therapy Agents

Brompheniramine and dexbrompheniramine are alkylamine Dextromethorphan, a derivative of levorphanol, is an antitussive agent. Phenylephrine hydrochloride is a sympathomimetic amine that predominantly (propylamine)-derivative first generation antihistamines. acts by a direct effect on alpha1-adrenergic receptors.

Brompheniramine and dexbrompheniramine share the actions and uses of other Dextromethorphan is used for the temporary relief of coughs caused by minor antihistamines. Preparations containing brompheniramine maleate or throat and bronchial irritation such as may occur with common colds or with dexbrompheniramine maleate in fixed combination with other agents (e.g., inhaled irritants. Dextromethorphan is most effective in the treatment of chronic, nonproductive cough. The drug is a common ingredient in commercial dextromethorphan, guaifenesin, phenylephrine, pseudoephedrine) are used for cough mixtures available without prescription. relief of rhinorrhea, sneezing, lacrimation, itching eyes, oronasopharyngeal itching, and/or other symptoms (e.g., nasal/sinus Although cough and cold preparations that contain cough suppressants congestion, cough) associated with allergic rhinitis (e.g., hay fever), (including dextromethorphan), nasal decongestants, antihistamines, and/or other upper respiratory allergies, or the common cold.

Combination expectorants commonly are used in pediatric patients younger than 2 years preparations generally should only be used when symptoms amenable to each ingredient are present concurrently. of age, systematic reviews of controlled trials have concluded that nonprescription (over-the-counter, OTC) cough and cold preparations are not more effective than placebo in reducing acute cough and other symptoms of upper respiratory tract infection in these patients. Furthermore, adverse events, including deaths, have been (and continue to be) reported in pediatric patients younger than 2 years of age receiving these preparations.

(See Cautions: Pediatric Precautions and see Acute Toxicity: Manifestations.) For information on abuse of dextromethorphan, see Cautions. For use of dextromethorphan hydrobromide in fixed combination with quinidine sulfate in the treatment of pseudobulbar affect (PBA), see Dextromethorphan Hydrobromide and Quinidine Sulfate 28:92.
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The following indications for ALTIPRES-B (brompheniramine maleate/phenylephrine hcl/dextromethorphan) have been approved by the FDA:

Indications:
Allergic rhinitis
Cold symptoms
Cough
Nasal congestion
Rhinorrhea
Vasomotor rhinitis


Professional Synonyms:
Nasal stuffiness