Vicectin

Drug overview for VICECTIN (ginger root/pyridoxine hcl (vitamin b6)):

Generic name: ginger root/pyridoxine HCl (vitamin B6)
Drug class:
Therapeutic class: Alternative Therapy

Vitamin B6 (as pyridoxine, pyridoxal, and pyridoxamine) is a water-soluble, B complex vitamin.

No enhanced Uses information available for this drug.

DRUG IMAGES

No Image Available

The following indications for VICECTIN (ginger root/pyridoxine hcl (vitamin b6)) have been approved by the FDA:

Indications:
None.

Professional Synonyms:
None.

The following drug interaction information is available for VICECTIN (ginger root/pyridoxine hcl (vitamin b6)):

Contraindicated
Severe
Moderate

There are 0 contraindications.

There are 0 severe interactions.

There are 1 moderate interactions. The clinician should assess the patient’s characteristics and take action as needed. Actions required for moderate interactions include, but are not limited to, discontinuing one or both agents, adjusting dosage, altering administration.

Drug Interaction	Drug Names
Levodopa/Pyridoxine SEVERITY LEVEL: 3-Moderate Interaction: Assess the risk to the patient and take action as needed. MECHANISM OF ACTION: Pyridoxine increases levodopa metabolism, decreasing the amount of levodopa available to the central nervous system. CLINICAL EFFECTS: The pharmacologic effects of levodopa may be decreased. PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: Avoid pyridoxine in patients receiving levodopa alone; however, the interaction can be minimized by giving levodopa with a peripheral decarboxylase inhibitor (e.g. carbidopa, benserazide). DISCUSSION: In patients with Parkinson's disease, as little as 10 mg of pyridoxine may reverse the clinical benefits as well as the adverse effects of levodopa. Coadministration of levodopa with either carbidopa or benserazide has minimized the effects of this interaction.	INBRIJA, LEVODOPA

Drug Interaction

Drug Names

Levodopa/Pyridoxine

SEVERITY LEVEL: 3-Moderate Interaction: Assess the risk to the patient and take action as needed.

MECHANISM OF ACTION: Pyridoxine increases levodopa metabolism, decreasing the amount of levodopa available to the central nervous system.

CLINICAL EFFECTS: The pharmacologic effects of levodopa may be decreased.

PREDISPOSING FACTORS: None determined.

PATIENT MANAGEMENT: Avoid pyridoxine in patients receiving levodopa alone; however, the interaction can be minimized by giving levodopa with a peripheral decarboxylase inhibitor (e.g. carbidopa, benserazide).

DISCUSSION: In patients with Parkinson's disease, as little as 10 mg of pyridoxine may reverse the clinical benefits as well as the adverse effects of levodopa. Coadministration of levodopa with either carbidopa or benserazide has minimized the effects of this interaction.

INBRIJA, LEVODOPA

Moderate List
Biliary calculus
Diabetes mellitus
Increased risk of bleeding due to coagulation disorder
Invasive surgical procedure

More Frequent	Less Frequent
None.	None.

Rare/Very Rare
Bruising Diarrhea Dizziness Drowsy Dyspepsia Flushing Heartburn Sedation Urticaria

The following precautions are available for VICECTIN (ginger root/pyridoxine hcl (vitamin b6)):

Pediatric
Pregnant
Lactation
Geriatric

No enhanced Pediatric Use information available for this drug.

Contraindicated

None

Severe Precaution

None

Management or Monitoring Precaution

None

No enhanced Pregnancy information available for this drug.

No enhanced Lactation information available for this drug.

No enhanced Geriatric Use information available for this drug.