Acticarnitine Sf

Drug overview for ACTICARNITINE SF (levocarnitine):

Generic name: levocarnitine (lee-voh-KAR-nih-teen)
Drug class: Levocarnitine
Therapeutic class: Electrolyte Balance-Nutritional Products

Amino acid derivative; naturally occurring substance required in mammalian energy metabolism.

No enhanced Uses information available for this drug.

DRUG IMAGES

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The following indications for ACTICARNITINE SF (levocarnitine) have been approved by the FDA:

Indications:
None.

Professional Synonyms:
None.

Contraindication List
Chronic kidney disease stage 5 (failure) GFr<15 ml/min

Moderate List
Seizure disorder

The following adverse reaction information is available for ACTICARNITINE SF (levocarnitine):

Overview
Severe
Less Severe

Adverse reaction overview.

Oral therapy: Transient nausea and vomiting, abdominal cramps, diarrhea, body odor. Parenteral therapy: Transient nausea and vomiting, body odor, gastritis. Patients on chronic hemodialysis may experience injection site reactions, headache, pain, diarrhea, flu syndrome, pharyngitis, infection, hypertension, vomiting, abdominal pain, hypotension, dizziness, increased cough, chest pain, hypercalcemia, accidental injury, asthenia, nausea, fever, anemia, hypervolemia, paresthesia, rhinitis, or dyspnea.

Seizures reported in patients, with or without preexisting seizure activity, receiving either oral or IV levocarnitine. Increased seizure frequency and/or severity also reported in patients with preexisting seizure activity.

There are 5 severe adverse reactions.

More Frequent	Less Frequent
None.	None.

Rare/Very Rare
Anaphylaxis Bronchospastic pulmonary disease Laryngeal edema Muscle weakness Seizure disorder

There are 9 less severe adverse reactions.

More Frequent	Less Frequent
Abdominal pain with cramps Diarrhea Nausea Vomiting	Body odor Gastritis

Rare/Very Rare
Facial edema Skin rash Urticaria

The following precautions are available for ACTICARNITINE SF (levocarnitine):

Pediatric
Pregnant
Lactation
Geriatric

Dosage of levocarnitine in pediatric patients <=18 years of age was based on specific patient case record observations rather than on studies that specifically defined age by protocol.

Contraindicated

None

Severe Precaution

None

Management or Monitoring Precaution

None

Category B.

Distributed into milk in cows; not known whether levocarnitine distributes into human milk. Consider discontinuance of nursing or the drug.

No enhanced Geriatric Use information available for this drug.