TARKA (TRANDOLAPRIL/VERAPAMIL HCL)
- Hypertension
- Trandolapril-verapamil Tablet, Immed - Ext Release 24Hr
- Trandolapril-verapamil Er Tablet,extended Release 24 Hr Mp
- Tarka Tablet,extended Release
- Tarka Tablet, Extended Release
- By Indication
trandolapril 1 mg-verapamil ER 240 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
trandolapril 2 mg-verapamil ER 180 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
trandolapril 2 mg-verapamil ER 240 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
trandolapril 4 mg-verapamil ER 240 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
trandolapril 1 mg-verapamil ER 240 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
trandolapril 2 mg-verapamil ER 180 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
trandolapril 2 mg-verapamil ER 240 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
trandolapril 4 mg-verapamil ER 240 mg tablet,immed-exten release 24 hr
- 1 tablet by oral route once daily with food
2 mg-180 mg tablet, extended release
- 1 tablet by oral route once daily with food
2 mg-240 mg tablet, extended release
- 1 tablet by oral route once daily with food
4 mg-240 mg tablet, extended release
- 1 tablet by oral route once daily with food
2 mg-180 mg tablet, extended release
- 1 tablet by oral route once daily with food
2 mg-240 mg tablet, extended release
- 1 tablet by oral route once daily with food
4 mg-240 mg tablet, extended release
- 1 tablet by oral route once daily with food
Hypertension
- 1 tablet by oral route once daily with food
- dofetilide
- ezetimibe-simvastatin
- Juxtapid
- lomitapide
- niacin-simvastatin
- Simcor
- Tikosyn
- Vytorin 10-20
- Vytorin 10-40
- Vytorin 10-80
Contraindicated
- abobotulinumtoxinA
- aliskiren
- aliskiren-amlodipin-hcthiazide
- aliskiren-amlodipine
- aliskiren-hydrochlorothiazide
- amiodarone
- amiodarone in dextrose,iso-osm
- amoxicil-clarithromy-lansopraz
- Amturnide
- Anectine
- Anzemet
- atracurium
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- Bosulif
- bosutinib
- Botox
- Botox Cosmetic
- cisatracurium
- clarithromycin
- colchicine
- colchicine-probenecid
- Colcrys
- Cordarone
- Curad Enema
- Dantrium
- dantrolene
- Digox
- digoxin
- Disposable Enema
- dolasetron
- Dysport
- Enema
- Enema Disposable
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- fingolimod
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- Gilenya
- guanfacine
- Hycamtin
- ibrutinib
- Imbruvica
- incobotulinumtoxinA
- Intuniv Er
- Ketek
- Lanoxin
- Lanoxin Pediatric
- lithium carbonate
- lithium citrate
- Lithobid
- midazolam
- midazolam (PF)
- Myobloc
- Nexterone
- Nimbex
- Olysio
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- onabotulinumtoxinA
- Oral Saline Laxative
- Orap
- Osmoprep
- Pacerone
- pancuronium
- Phosphate Laxative
- pimozide
- Preparation Cleansing
- Prevpac
- Quelicin
- Ready-to-use Enema
- Revonto
- rimabotulinumtoxinB
- rocuronium
- Samsca
- simeprevir
- sod phos mono-sod phos dibasic
- sodium phosphates
- succinylcholine chloride
- Tekamlo
- Tekturna
- Tekturna Hct
- telithromycin
- Tenex
- tizanidine
- tolvaptan
- topotecan
- triazolam
- vecuronium bromide
- Xeomin
- Zanaflex
- Zemuron
Severe
Moderate
- Abstral
- acebutolol
- Actiq
- Added Strength Headache Relief
- Added Strength Pain Reliever
- Advicor
- afatinib
- Afinitor
- Afinitor Disperz
- Alfenta
- alfentanil
- Alka-seltzer
- Alka-seltzer Extra Strength
- Alka-seltzer Original
- Alka-seltzer Plus C/c(pe,dm)
- Alka-seltzer Plus Cold (pe)
- Alka-seltzer Plus Day-night
- Alka-seltzer Plus Night
- Alka-seltzer Pm
- Altoprev
- amlodipine-atorvastatin
- Anacin
- Anacin Maximum Strength
- Analgesic
- Angeliq
- Antacid & Pain Relief
- Anti-diarrhea
- Anti-diarrheal (lope)-anti-gas
- Anti-diarrheal (loperamide)
- ASA-acetaminophen-caff-buffers
- ASA-acetaminophen-salicyl-caff
- Ascomp With Codeine
- Aspir-trin
- aspirin
- aspirin, buffered
- aspirin-acetaminophen-caffeine
- aspirin-caffeine
- aspirin-diphenhydramine
- aspirin-diphenhydramine citrat
- aspirin-sod bicarb-citric acid
- Astagraf Xl
- atenolol
- atenolol-chlorthalidone
- atorvastatin
- avanafil
- Azasan
- azathioprine
- azathioprine sodium
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Back & Body Pain Reliever
- Bactrim
- Bactrim Ds
- Bayer Advanced
- Bayer Aspirin
- Bayer Aspirin (with Caffeine)
- Bayer Back & Body
- Bayer Plus Extra Strength
- Bayer Pm
- Bc
- Bc Arthritis
- Betapace
- Betapace Af
- Betimol
- Beyaz
- boceprevir
- bosentan
- brimonidine-timolol
- Buffered Aspirin
- Bufferin
- bumetanide
- buspirone
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-aspirin-caffeine
- Bystolic
- Caduet
- calcium-mag-B complex-D3-hrb61
- carbamazepine
- Carbatrol
- carisoprodol-ASA-codeine
- carisoprodol-aspirin
- chlorphen-phenyleph-DM-aspirin
- chlorphenir-phenylephrn-aspirn
- cilostazol
- codeine-butalbital-ASA-caff
- Cold & Flu Fighter
- Cold Relief
- Cold Relief Plus
- Combigan
- Corgard
- Corzide
- Cosopt
- Cosopt Pf
- cyclosporine
- cyclosporine modified
- Demadex
- dextromethorphan-quinidine
- Diamode
- dihydrocodeine-aspirin-caff
- dorzolamide-timolol
- dorzolamide-timolol (PF)
- doxylamine-phenylep-DM-aspirin
- dronedarone
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- Duragesic
- dutasteride-tamsulosin
- Dutoprol
- E.c. Prin
- Ecotrin
- Efferves Pain Relief Antacid
- Effervescent Antacid
- Effervescent Pain Relief
- Effervescent Pain Reliever
- Endocet
- Endodan
- Epitol
- eplerenone
- Equetro
- ethacrynate sodium
- Etopophos
- etoposide
- etoposide phosphate
- everolimus
- Excedrin Extra Strength
- Excedrin Migraine
- Extra Strength Bayer
- ezetimibe-atorvastatin
- Fatigue Relief Complex
- fentanyl
- fentanyl citrate
- fentanyl citrate (PF)
- Fentora
- Fiorinal
- Fiorinal-codeine #3
- Flomax
- furosemide
- Gengraf
- Gianvi (28)
- Gilotrif
- Goody's Extra Strength
- Goody's Migraine Relief
- Headache Formula
- Headache Formula Added Str
- Headache Relief
- Hecoria
- ibuprofen-oxycodone
- Imodium Multi-symptom Relief
- Imuran
- Incivek
- Inderal La
- Inderal Xl
- Innopran Xl
- Inspra
- isoniazid-rifamp-pyrazinamide
- Istalol
- ivacaftor
- Jalyn
- Kalydeco
- ketoconazole
- labetalol
- Lasix
- Latuda
- Lazanda
- Levacet
- Levitra
- Lipitor
- Liptruzet
- Lite Coat Aspirin
- Lo-peramide
- loperamide
- loperamide-simethicone
- Lopressor
- Lopressor Hct
- Loryna (28)
- lovastatin
- lurasidone
- Medi-seltzer
- mercaptopurine
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Mevacor
- Migraine Formula
- Migraine Pain Reliever
- Migraine Relief
- Minipress
- Multaq
- Mycobutin
- nadolol
- nadolol-bendroflumethiazide
- nebivolol
- Neoral
- niacin-lovastatin
- Nuedexta
- Ocella
- Orphenadrine Compound Forte
- Orphenadrine Compound-ds
- orphenadrine-ASA-caffeine
- Oxecta
- oxycodone
- oxycodone-acetaminophen
- oxycodone-aspirin
- Oxycontin
- Pain Relief
- Pain Relief Extra Strength
- Pain Reliever
- Pain Reliever Extra Strength
- Pain Reliever Plus
- Pain-off
- Pamprin Max
- PE-DM-ASA/doxyla-PE-DM-ASA
- Percocet
- Percodan
- pindolol
- Pletal
- prazosin
- Priftin
- Primlev
- Primsol
- Prograf
- propranolol
- propranolol-hydrochlorothiazid
- Purinethol
- quinidine gluconate
- quinidine sulfate
- Rapamune
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- Roxicet
- Safyral
- Sandimmune
- Sectral
- simvastatin
- sirolimus
- Sodium Edecrin
- Sorine
- sotalol
- Sotalol Af
- St. John's wort
- Stendra
- Sublimaze (pf)
- Subsys
- sulfamethoxazole-trimethoprim
- Sulfatrim
- Super Pain Relief
- Syeda
- Synalgos-dc
- tacrolimus
- tamsulosin
- Tegretol
- Tegretol Xr
- telaprevir
- temsirolimus
- Tenoretic 100
- Tenoretic 50
- Tenormin
- terazosin
- timolol
- timolol maleate
- timolol maleate (PF)
- Timoptic
- Timoptic Ocudose (pf)
- Timoptic-xe
- Toposar
- Toprol Xl
- Torisel
- torsemide
- Tracleer
- Trandate
- Tri-buffered Aspirin
- trimethoprim
- Ultra A-d
- Vanquish
- vardenafil
- Vestura (28)
- Victrelis
- vit C-St. John wort-elder-hb30
- Vytorin 10-10
- Women's Complex
- Xartemis Xr
- Yasmin (28)
- Yaz 28
- Zarah
- Zocor
- Zortress
- Cardiogenic shock
- Complete atrioventricular block
- Low cardiac output
- Lown-ganong-levine syndrome
- Pregnancy
- Second degree atrioventricular heart block
- Severe chronic heart failure
- Severe hypotension
- Wolff-parkinson-white pattern
Contraindicated
- Abnormal hepatic function tests
- Angioedema
- Bradycardia
- Chronic idiopathic constipation
- Dehydration
- Disease of liver
- Duchenne muscular dystrophy
- First degree atrioventricular heart block
- Hemodialysis with high-flux membrane
- Hyperkalemia
- Hyponatremia
- Hypotension
- Left ventricular failure
- Myasthenia gravis
- Neuromuscular transmission deficiency
- Sick sinus syndrome
- Ventricular tachycardia
Severe
Moderate
- Agranulocytosis
- Bone marrow depression
- Disease of liver
- Kidney disease with reduction in GFR
- Neutropenic disorder
- Renal artery stenosis
TARKA (TRANDOLAPRIL/VERAPAMIL HCL)
- Hypertension
- None
- Constipation
- Dizziness
- Flu-like symptoms
- Headache disorder
- Infection
- Peripheral edema
- Pharyngitis
- Sinusitis
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Bradycardia
- Chronic heart failure
- Dizziness
- Dyspnea
- Hypotension
- Pulmonary edema
- Cough
- Diarrhea
- Dyspepsia
- Edema
- Fatigue
- General weakness
- Nausea
- Rhinitis
- Skin rash
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal ECG
- Abnormal hepatic function tests
- Acute myocardial infarction
- Acute renal failure
- Agranulocytosis
- Anaphylaxis
- Angioedema
- Atrioventricular block
- Bradycardia
- Cardiac arrhythmia
- Cerebrovascular accident
- Drug-induced psychosis
- Dyspnea
- Eosinophilic pneumonia
- Erythema multiforme
- Extrapyramidal disease
- Galactorrhea not associated with childbirth
- Gingival hyperplasia
- Gout
- Head and neck angioedema
- Hepatic necrosis
- Hepatitis
- Hepatocellular damage
- Hyperbilirubinemia
- Hyperkalemia
- Hyperprolactinemia
- Hypocalcemia
- Hyponatremia
- Hypotension
- Increased alanine transaminase
- Increased aspartate transaminase
- Intermittent claudication
- Intestinal angioedema
- Intracerebral hemorrhage
- Jaundice
- Laryngeal edema
- Leukopenia
- Neutropenic disorder
- Obstructive hyperbilirubinemia
- Pancreatitis
- Pemphigus
- Severe hypotension
- Stevens-johnson syndrome
- Syncope
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Transient cerebral ischemia
Less Severe
- Abdominal distension
- Abdominal pain with cramps
- Acute confusion
- Alopecia
- Arthralgias
- Blurred vision
- Bronchitis
- Constipation
- Cramps
- Depression
- Diarrhea
- Drowsy
- Dyspepsia
- Ecchymosis
- Edema
- Epistaxis
- Erectile dysfunction
- Fever
- Flushing
- Gastritis
- General weakness
- Gynecomastia
- Hallucinations
- Hyperbilirubinemia
- Hyperhidrosis
- Increased urinary frequency
- Insomnia
- Libido changes
- Limb pain
- Malaise
- Menstrual disorder
- Myalgias
- Nausea
- Palpitations
- Paresthesia
- Pruritus of skin
- Purpura
- Skin rash
- Symptoms of anxiety
- Tinnitus
- Tremor
- Vertigo
- Vomiting
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Trandolapril
Safety and efficacy not established.
Safety and efficacy of oral dose form not established. Dosing guidelines available.
- 1 Day – 18 Years
- Safety and efficacy not established.
Verapamil (Oral)
Safety and efficacy not established.
Safety and efficacy of oral dose form not established. Dosing guidelines available.
- 1 Day – 18 Years
- Safety and efficacy of oral dose form not established. Dosing guidelines available.
Trandolapril
- Severity Level:
1
- Additional Notes: Fetal death/morbidity w/use in 2nd & 3rd trimester, stop when pregnancy detected
Verapamil Hydrochloride
- Severity Level:
C
- Additional Notes:
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Trandolapril
Excreted in rats; insufficient human data available; mfr does not rec
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Excreted in rats; insufficient human data available; mfr does not rec |
No Known Risk
Verapamil Hydrochloride
Limited data suggest infant levels are low with no resulting adverse effects
General | Excretion Potential | Effect on Infant | Notes |
No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Limited data suggest infant levels are low with no resulting adverse effects |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Trandolapril can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this product. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this product. If you are planning pregnancy, become pregnant, or think you may be pregnant, tell your doctor right away.
Hypertension | |
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |
0-9 | A-Z |
---|---|
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |