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TRECATOR (ETHIONAMIDE)
- Active tuberculosis
- Pulmonary tuberculosis
250 mg tablet
- 1 tablet (250 mg) by oral route every 12 hours
Atypical mycobacterial infection
- 15 mg/kg by oral route once daily not to exceed 1 g in 24 hrs
- 20 mg/kg by oral route once daily not to exceed 1 g in 24 hrs
- 1 tablet (250 mg) by oral route every 8 hours
- 1 tablet (250 mg) by oral route every 12 hours
Leprosy
- 1 tablet (250 mg) by oral route once daily
- 1 tablet (250 mg) by oral route every 8 hours
- 1 tablet (250 mg) by oral route every 12 hours
- 2 tablets (500 mg) by oral route once daily
Pulmonary tuberculosis
- 15 mg/kg by oral route once daily not to exceed 1 g in 24 hrs
- 20 mg/kg by oral route once daily not to exceed 1 g in 24 hrs
- 1 tablet (250 mg) by oral route every 8 hours
- 1 tablet (250 mg) by oral route every 12 hours
Tuberculosis meningitis
- 15 mg/kg by oral route once daily not to exceed 1 g in 24 hrs
- 20 mg/kg by oral route once daily not to exceed 1 g in 24 hrs
- 1 tablet (250 mg) by oral route every 8 hours
- 1 tablet (250 mg) by oral route every 12 hours
- typhoid vaccine
- Vivotif Berna Vaccine
Contraindicated
- BCG live
- BCG vaccine, live (PF)
- Tice Bcg
Severe
Moderate
- None
- Pregnancy
- Severe hepatic disease
Contraindicated
- Alcoholism
- Disease of liver
Severe
Moderate
- Diabetes mellitus
- Hypothyroidism
TRECATOR (ETHIONAMIDE)
- Active tuberculosis
- Pulmonary tuberculosis
- Stomatitis
- Acute abdominal pain
- Anorexia
- Diarrhea
- Dysgeusia
- Nausea
- Orthostatic hypotension
- Vomiting
More Frequent
Severe
Less Severe
- Blurred vision
- Hepatitis
- Jaundice
- Peripheral neuropathy
- Psychiatric disorder
- Dizziness
- Drowsy
- Headache disorder
- Nervousness
- Sialorrhea
- Weight loss
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Depression
- Diplopia
- Drug-induced psychosis
- Goiter
- Hypersensitivity drug reaction
- Hypoglycemic disorder
- Hypothyroidism
- Optic neuritis
- Purpura
- Skin rash
- Thrombocytopenic disorder
Less Severe
- Acne vulgaris
- Erectile dysfunction
- Gynecomastia
- Skin photosensitivity
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Ethionamide
Reserve use for resistant cases, systemic dissemination or life threatening complication of TB. Limited safety data.
- 1 Day – 12 Years
- Reserve use for resistant cases, systemic dissemination or life threatening complication of TB. Limited safety data.
Ethionamide
- Severity Level:
1
- Additional Notes: Fda c; animal studies demonstrate teratogenic potential; not recommended.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Ethionamide
No data available. molecular wt low enough for possible breastmilk excretion
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | No data available. molecular wt low enough for possible breastmilk excretion |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Active tuberculosis | |
| A15 | Respiratory tuberculosis |
| A15.0 | Tuberculosis of lung |
| A15.4 | Tuberculosis of intrathoracic lymph nodes |
| A15.5 | Tuberculosis of larynx, trachea and bronchus |
| A15.6 | Tuberculous pleurisy |
| A15.7 | Primary respiratory tuberculosis |
| A15.8 | Other respiratory tuberculosis |
| A15.9 | Respiratory tuberculosis unspecified |
| A17 | Tuberculosis of nervous system |
| A17.0 | Tuberculous meningitis |
| A17.1 | Meningeal tuberculoma |
| A17.8 | Other tuberculosis of nervous system |
| A17.81 | Tuberculoma of brain and spinal cord |
| A17.82 | Tuberculous meningoencephalitis |
| A17.83 | Tuberculous neuritis |
| A17.89 | Other tuberculosis of nervous system |
| A17.9 | Tuberculosis of nervous system, unspecified |
| A18 | Tuberculosis of other organs |
| A18.0 | Tuberculosis of bones and joints |
| A18.01 | Tuberculosis of spine |
| A18.02 | Tuberculous arthritis of other joints |
| A18.03 | Tuberculosis of other bones |
| A18.09 | Other musculoskeletal tuberculosis |
| A18.1 | Tuberculosis of genitourinary system |
| A18.10 | Tuberculosis of genitourinary system, unspecified |
| A18.11 | Tuberculosis of kidney and ureter |
| A18.12 | Tuberculosis of bladder |
| A18.13 | Tuberculosis of other urinary organs |
| A18.14 | Tuberculosis of prostate |
| A18.15 | Tuberculosis of other male genital organs |
| A18.16 | Tuberculosis of cervix |
| A18.17 | Tuberculous female pelvic inflammatory disease |
| A18.18 | Tuberculosis of other female genital organs |
| A18.2 | Tuberculous peripheral lymphadenopathy |
| A18.3 | Tuberculosis of intestines, peritoneum and mesenteric glands |
| A18.31 | Tuberculous peritonitis |
| A18.32 | Tuberculous enteritis |
| A18.39 | Retroperitoneal tuberculosis |
| A18.4 | Tuberculosis of skin and subcutaneous tissue |
| A18.5 | Tuberculosis of eye |
| A18.50 | Tuberculosis of eye, unspecified |
| A18.51 | Tuberculous episcleritis |
| A18.52 | Tuberculous keratitis |
| A18.53 | Tuberculous chorioretinitis |
| A18.54 | Tuberculous iridocyclitis |
| A18.59 | Other tuberculosis of eye |
| A18.6 | Tuberculosis of (inner) (middle) ear |
| A18.7 | Tuberculosis of adrenal glands |
| A18.8 | Tuberculosis of other specified organs |
| A18.81 | Tuberculosis of thyroid gland |
| A18.82 | Tuberculosis of other endocrine glands |
| A18.83 | Tuberculosis of digestive tract organs, not elsewhere classified |
| A18.84 | Tuberculosis of heart |
| A18.85 | Tuberculosis of spleen |
| A18.89 | Tuberculosis of other sites |
| A19 | Miliary tuberculosis |
| A19.0 | Acute miliary tuberculosis of a single specified site |
| A19.1 | Acute miliary tuberculosis of multiple sites |
| A19.2 | Acute miliary tuberculosis, unspecified |
| A19.8 | Other miliary tuberculosis |
| A19.9 | Miliary tuberculosis, unspecified |
| O98.0 | Tuberculosis complicating pregnancy, childbirth and the puerperium |
| O98.01 | Tuberculosis complicating pregnancy |
| O98.011 | Tuberculosis complicating pregnancy, first trimester |
| O98.012 | Tuberculosis complicating pregnancy, second trimester |
| O98.013 | Tuberculosis complicating pregnancy, third trimester |
| O98.019 | Tuberculosis complicating pregnancy, unspecified trimester |
| O98.02 | Tuberculosis complicating childbirth |
| O98.03 | Tuberculosis complicating the puerperium |
| P37.0 | Congenital tuberculosis |
| Pulmonary tuberculosis | |
| A15 | Respiratory tuberculosis |
| A15.0 | Tuberculosis of lung |
| A15.7 | Primary respiratory tuberculosis |
| A15.8 | Other respiratory tuberculosis |
| 0-9 | A-Z |
|---|---|
| A15 | Respiratory tuberculosis |
| A15 | Respiratory tuberculosis |
| A15.0 | Tuberculosis of lung |
| A15.0 | Tuberculosis of lung |
| A15.4 | Tuberculosis of intrathoracic lymph nodes |
| A15.5 | Tuberculosis of larynx, trachea and bronchus |
| A15.6 | Tuberculous pleurisy |
| A15.7 | Primary respiratory tuberculosis |
| A15.7 | Primary respiratory tuberculosis |
| A15.8 | Other respiratory tuberculosis |
| A15.8 | Other respiratory tuberculosis |
| A15.9 | Respiratory tuberculosis unspecified |
| A17 | Tuberculosis of nervous system |
| A17.0 | Tuberculous meningitis |
| A17.1 | Meningeal tuberculoma |
| A17.8 | Other tuberculosis of nervous system |
| A17.81 | Tuberculoma of brain and spinal cord |
| A17.82 | Tuberculous meningoencephalitis |
| A17.83 | Tuberculous neuritis |
| A17.89 | Other tuberculosis of nervous system |
| A17.9 | Tuberculosis of nervous system, unspecified |
| A18 | Tuberculosis of other organs |
| A18.0 | Tuberculosis of bones and joints |
| A18.01 | Tuberculosis of spine |
| A18.02 | Tuberculous arthritis of other joints |
| A18.03 | Tuberculosis of other bones |
| A18.09 | Other musculoskeletal tuberculosis |
| A18.1 | Tuberculosis of genitourinary system |
| A18.10 | Tuberculosis of genitourinary system, unspecified |
| A18.11 | Tuberculosis of kidney and ureter |
| A18.12 | Tuberculosis of bladder |
| A18.13 | Tuberculosis of other urinary organs |
| A18.14 | Tuberculosis of prostate |
| A18.15 | Tuberculosis of other male genital organs |
| A18.16 | Tuberculosis of cervix |
| A18.17 | Tuberculous female pelvic inflammatory disease |
| A18.18 | Tuberculosis of other female genital organs |
| A18.2 | Tuberculous peripheral lymphadenopathy |
| A18.3 | Tuberculosis of intestines, peritoneum and mesenteric glands |
| A18.31 | Tuberculous peritonitis |
| A18.32 | Tuberculous enteritis |
| A18.39 | Retroperitoneal tuberculosis |
| A18.4 | Tuberculosis of skin and subcutaneous tissue |
| A18.5 | Tuberculosis of eye |
| A18.50 | Tuberculosis of eye, unspecified |
| A18.51 | Tuberculous episcleritis |
| A18.52 | Tuberculous keratitis |
| A18.53 | Tuberculous chorioretinitis |
| A18.54 | Tuberculous iridocyclitis |
| A18.59 | Other tuberculosis of eye |
| A18.6 | Tuberculosis of (inner) (middle) ear |
| A18.7 | Tuberculosis of adrenal glands |
| A18.8 | Tuberculosis of other specified organs |
| A18.81 | Tuberculosis of thyroid gland |
| A18.82 | Tuberculosis of other endocrine glands |
| A18.83 | Tuberculosis of digestive tract organs, not elsewhere classified |
| A18.84 | Tuberculosis of heart |
| A18.85 | Tuberculosis of spleen |
| A18.89 | Tuberculosis of other sites |
| A19 | Miliary tuberculosis |
| A19.0 | Acute miliary tuberculosis of a single specified site |
| A19.1 | Acute miliary tuberculosis of multiple sites |
| A19.2 | Acute miliary tuberculosis, unspecified |
| A19.8 | Other miliary tuberculosis |
| A19.9 | Miliary tuberculosis, unspecified |
| O98.0 | Tuberculosis complicating pregnancy, childbirth and the puerperium |
| O98.01 | Tuberculosis complicating pregnancy |
| O98.011 | Tuberculosis complicating pregnancy, first trimester |
| O98.012 | Tuberculosis complicating pregnancy, second trimester |
| O98.013 | Tuberculosis complicating pregnancy, third trimester |
| O98.019 | Tuberculosis complicating pregnancy, unspecified trimester |
| O98.02 | Tuberculosis complicating childbirth |
| O98.03 | Tuberculosis complicating the puerperium |
| P37.0 | Congenital tuberculosis |
Formulary Reference Tool