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WAL-FEX D 24 HOUR (FEXOFENADINE HCL/PSEUDOEPHEDRINE HCL)
- Allergic conjunctivitis
- Allergic rhinitis
- Sneezing
- Wal-fex D 24 Hour Tablet,extended Release
- Fexofenadine-pseudoephedrine Er Tablet,ext.release 24 Hr
- Allegra-d 24 Hour Tablet,extended Release
- Allegra-d 24 Hour Tab
- By Indication
180 mg-240 mg tablet,extended release
- 1 tablet by oral route once daily on an empty stomach with glassof water
fexofenadine-pseudoephedrine ER 180 mg-240 mg tablet,ext.release 24 hr
- 1 tablet by oral route once daily on an empty stomach with glassof water
180 mg-240 mg tablet,extended release
- 1 tablet by oral route once daily on an empty stomach with glassof water
180 mg-240 mg tablet,extended release
- 1 tablet by oral route once daily on an empty stomach with glassof water
Allergic conjunctivitis
- 1 tablet by oral route once daily on an empty stomach with glassof water
Allergic rhinitis
- 1 tablet by oral route once daily on an empty stomach with glassof water
Sneezing
- 1 tablet by oral route once daily on an empty stomach with glassof water
- isocarboxazid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- tranylcypromine
Contraindicated
- Azilect
- bromocriptine
- cabergoline
- Cafergot
- Cycloset
- D.h.e.45
- dihydroergotamine
- Eldepryl
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- linezolid
- methylergonovine
- Migergot
- Migranal
- Parlodel
- rasagiline
- selegiline HCl
- Zelapar
- Zyvox
Severe
Moderate
- methyldopa
- methyldopa-hydrochlorothiazide
- methyldopate
- reserpine
- Angle-closure glaucoma
- Severe coronary artery disease
- Severe uncontrolled hypertension
- Urinary retention
Contraindicated
- Benign prostatic hyperplasia
- Diabetes mellitus
- Hypertension
- Hyperthyroidism
Severe
Moderate
- Kidney disease with reduction in GFR
WAL-FEX D 24 HOUR (FEXOFENADINE HCL/PSEUDOEPHEDRINE HCL)
- Allergic conjunctivitis
- Allergic rhinitis
- Sneezing
- None
- Headache disorder
- Insomnia
More Frequent
Severe
Less Severe
- None
- Agitation
- Anorexia
- Back pain
- Dizziness
- Drowsy
- Dysmenorrhea
- Dyspepsia
- Dysuria
- Fatigue
- General weakness
- Headache disorder
- Myalgias
- Nausea
- Nervousness
- Pallor
- Pharyngitis
- Sinusitis
- Skin rash
- Tachycardia
- Tremor
- Viral infection
- Vomiting
- Xerostomia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute bacterial otitis media
- Acute generalized exanthematous pustulosis
- Anaphylaxis
- Dyspnea
- Hallucinations
- Hypersensitivity drug reaction
- Hypertension
- Ischemic colitis
- Seizure disorder
- Upper respiratory infection
- Urticaria
- Vomiting
Less Severe
- Abdominal pain with cramps
- Agitation
- Cardiac arrhythmia
- Cough
- Dyspepsia
- Earache
- Excitement
- Fever
- Hyperhidrosis
- Insomnia
- Nervousness
- Nightmares
- Pain
- Palpitations
- Pruritus of skin
- Symptoms of anxiety
Contraindicated
Pseudoephedrine (SR or High Dose)
Increased sensitivity to side effects. Dose form or strength not appropriate.
- 1 Day – 12 Years
- 1 Increased sensitivity to side effects. Dose form or strength not appropriate.
Severe Precaution
None
Management or Monitoring Precaution
Fexofenadine
Safety & efficacy in children less than 6 months not established.
Increased incidence of vomiting, diarrhea, somnolence, rhinorrhea age < 5 years.
- 1 Day – 179 Days
- Safety & efficacy in children less than 6 months not established.
- Increased incidence of vomiting, diarrhea, somnolence, rhinorrhea age < 5 years.
- 180 Days – 5 Years
- Safety & efficacy in children less than 6 months not established.
- Increased incidence of vomiting, diarrhea, somnolence, rhinorrhea age < 5 years.
Fexofenadine
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Pseudoephedrine
- Severity Level:
C
- Additional Notes: Fda c w/combo prod; poss risk of gastroschisis/sia with 1st trimester exposure
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Fexofenadine
Insufficient data available; limited data suggest minimal amounts excreted
May decrease milk supply, and cause irritability
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Insufficient data available; limited data suggest minimal amounts excreted |
Pseudoephedrine
Insufficient data available; limited data suggest minimal amounts excreted
May decrease milk supply, and cause irritability
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Drug shown to have adverse effect | May decrease milk supply, and cause irritability |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Fexofenadine
Decrease daily dose for declining renal function (CLCR<80ml/min).
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
Pseudoephedrine
Decrease daily dose for declining renal function (CLCR<80ml/min).
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Allergic conjunctivitis | |
| H10.1 | Acute atopic conjunctivitis |
| H10.10 | Acute atopic conjunctivitis, unspecified eye |
| H10.11 | Acute atopic conjunctivitis, right eye |
| H10.12 | Acute atopic conjunctivitis, left eye |
| H10.13 | Acute atopic conjunctivitis, bilateral |
| H10.44 | Vernal conjunctivitis |
| H10.45 | Other chronic allergic conjunctivitis |
| H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
| H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
| H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
| H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
| H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
| Allergic rhinitis | |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| Sneezing | |
| R06.7 | Sneezing |
| 0-9 | A-Z |
|---|---|
| H10.1 | Acute atopic conjunctivitis |
| H10.10 | Acute atopic conjunctivitis, unspecified eye |
| H10.11 | Acute atopic conjunctivitis, right eye |
| H10.12 | Acute atopic conjunctivitis, left eye |
| H10.13 | Acute atopic conjunctivitis, bilateral |
| H10.44 | Vernal conjunctivitis |
| H10.45 | Other chronic allergic conjunctivitis |
| H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
| H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
| H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
| H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
| H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| R06.7 | Sneezing |
Formulary Reference Tool