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FENTANYL CITRATE (FENTANYL CITRATE/PF)
- Administration of general anesthesia
- General anesthesia adjunct
- Postoperative acute pain
- Regional anesthesia for postoperative pain
- Regional anesthesia for surgery
- Fentanyl (pf) Intravenous Syringe
- Fentanyl (pf) Intravenous Solution
- Fentanyl (pf) Intravenous Pca Syringe
fentanyl (PF) 100 mcg/2 mL (50 mcg/mL) intravenous syringe
- Dosage information is not available
fentanyl (PF) 250 mcg/5 mL (50 mcg/mL) intravenous syringe
- Dosage information is not available
fentanyl (PF) 50 mcg/mL intravenous syringe
- Dosage information is not available
fentanyl (PF) 500 mcg/10 mL (50 mcg/mL) intravenous syringe
- Dosage information is not available
fentanyl (PF) 50 mcg/mL intravenous solution
- Dosage information is not available
fentanyl (PF) 1,250 mcg/25 mL (50 mcg/mL) intravenous PCA syringe
- Dosage information is not available
fentanyl (PF) 1,500 mcg/30 mL (50 mcg/mL) intravenous PCA syringe
- Dosage information is not available
fentanyl (PF) 2,500 mcg/50 mL (50 mcg/mL) intravenous PCA syringe
- Dosage information is not available
fentanyl (PF) 2,750 mcg/55 mL (50 mcg/mL) intravenous PCA syringe
- Dosage information is not available
fentanyl (PF) 400 mcg/8 mL (50 mcg/mL) intravenous PCA syringe
- Dosage information is not available
- Azilect
- Depade
- Eldepryl
- isocarboxazid
- linezolid
- Marplan
- Matulane
- methylene blue (antidote)
- naltrexone
- naltrexone microspheres
- Nardil
- Parnate
- phenelzine
- procarbazine
- rasagiline
- Revia
- selegiline HCl
- tranylcypromine
- Vivitrol
- Zelapar
- Zyvox
Contraindicated
- amiodarone
- amiodarone in dextrose,iso-osm
- amoxicil-clarithromy-lansopraz
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- boceprevir
- clarithromycin
- conivaptan in 5 % dextrose
- Cordarone
- Crixivan
- Diflucan
- elvitegr-cobicist-emtric-tenof
- enzalutamide
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- Incivek
- indinavir
- Invirase
- itraconazole
- Kaletra
- Ketek
- ketoconazole
- lopinavir-ritonavir
- nefazodone
- nelfinavir
- Nexterone
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Onmel
- Pacerone
- posaconazole
- Prevpac
- ritonavir
- saquinavir mesylate
- sodium oxybate
- Sporanox
- Sporanox Pulsepak
- Stribild
- telaprevir
- telithromycin
- Vaprisol
- Vfend
- Vfend Iv
- Victrelis
- Viracept
- voriconazole
- Xtandi
- Xyrem
Severe
Moderate
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Anafranil
- aprepitant
- atazanavir
- Brintellix
- Brisdelle
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- butorphanol tartrate
- Butrans
- Calan
- Calan Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Celexa
- cimetidine
- Cipro
- Cipro In D5W
- Cipro Xr
- ciprofloxacin
- ciprofloxacin (mixture)
- ciprofloxacin in D5W
- citalopram
- clomipramine
- Cymbalta
- darunavir
- desvenlafaxine
- desvenlafaxine fumarate
- desvenlafaxine succinate
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- Diprivan
- dronedarone
- duloxetine
- Effexor Xr
- Emend
- escitalopram oxalate
- Fanatrex
- Fetzima
- fluoxetine
- fluvoxamine
- fosamprenavir
- fosaprepitant
- gabapentin
- gabapentin enacarbil
- Gleevec
- Gralise
- Gralise 30-day Starter Pack
- Heartburn Relief
- Horizant
- imatinib
- isoniazid-rifamp-pyrazinamide
- Khedezla
- levomilnacipran
- Lexapro
- Lexiva
- Luvox Cr
- Matzim La
- milnacipran
- Multaq
- nalbuphine
- Neurontin
- olanzapine-fluoxetine
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- Pexeva
- Prezista
- Pristiq
- propofol
- Prozac
- Prozac Weekly
- Reyataz
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- Sarafem
- Savella
- sertraline
- Suboxone
- Symbyax
- Tagamet Hb
- Tarka
- Taztia Xt
- Tiazac
- trandolapril-verapamil
- venlafaxine
- verapamil
- Verelan
- Verelan Pm
- Viibryd
- vilazodone
- vortioxetine
- Zoloft
- Zubsolv
- Acute asthma attack
- Paralytic ileus
- Sleep apnea
Contraindicated
- Adrenal cortical insufficiency
- Cardiogenic shock
- Cor pulmonale
- History of opioid overdose
- Inflammatory bowel disease
- Kidney disease with reduction in GFR
- Respiratory depression
Severe
Moderate
- Alcoholism
- Benign prostatic hyperplasia
- Biliary tract disorder
- Bradycardia
- Chronic obstructive pulmonary disease
- Disease of liver
- Drug abuse
- Intracranial hypertension
- Lower seizure threshold
- Seizure disorder
- Urethral stricture
FENTANYL CITRATE (FENTANYL CITRATE/PF)
- Administration of general anesthesia
- General anesthesia adjunct
- Postoperative acute pain
- Regional anesthesia for postoperative pain
- Regional anesthesia for surgery
- Bradycardia
- Hypotension
- Respiratory depression
- Drowsy
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- Cardiac arrhythmia
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute confusion
- Allergic dermatitis
- Bronchospastic pulmonary disease
- Circulatory depression
- Delirium
- Depression
- Disorder of adrenal gland
- Excitement
- Laryngismus
- Paresthesia
- Pruritus of skin
- Serotonin syndrome
- Skin rash
- Tonic clonic seizure
- Urticaria
Less Severe
- Biliary spasm
- Blurred vision
- Chills
- CNS depression
- Constipation
- Diplopia
- Erectile dysfunction
- Infertility
- Libido changes
- Orthostatic hypotension
- Ureteral spasm
- Visual changes
Contraindicated
None
Severe Precaution
Narcotic Analgesics, Systemic
Potential increased sensitivity to effects, adverse CNS effects and respiratory depression.
- 1 Day – 2 Years
- Potential increased sensitivity to effects, adverse CNS effects and respiratory depression.
Management or Monitoring Precaution
None
Fentanyl
- Severity Level:
2
- Additional Notes: Neonatal withdrawal/resp.depress. w/chronic or high dose
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Fentanyl
Insufficient data avail; low levels excreted with short term use
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Insufficient data avail; low levels excreted with short term use |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Fentanyl (systemic)
General-Consider adding naloxone Rx. Pulmonary-Life threatening respiratory depression risk with high doses, cachexia, or debilitation due to altered pharmacokinetics (poor fat stores, muscle wasting, or altered clearance). Monitor closely at initiation and dose titration. Neuro/Psych-Risk for increased confusion and delirium. May increase fall risk. Avoid treatment with 3 or more CNS active drugs. Gastrointestinal-Constipation risk. Urogenital-Urinary retention risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | Y | Y | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- None
| Postoperative acute pain | |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| Regional anesthesia for postoperative pain | |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| 0-9 | A-Z |
|---|---|
| G89.12 | Acute post-thoracotomy pain |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| G89.18 | Other acute postprocedural pain |
Formulary Reference Tool