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LIQREV (sildenafil citrate)
- pulmonary arterial hypertension
10 mg/mL oral suspension
- 2 milliliters (20 mg) by oral route 3 times per day
Default screening record
- 2 milliliters (20 mg) by oral route 3 times per day
- Adempas
- atazanavir
- Bidil
- boceprevir
- Crixivan
- Dilatrate-sr
- elvitegr-cobicist-emtric-tenof
- fosamprenavir
- Imdur
- Incivek
- indinavir
- Isochron
- Isoditrate
- isosorbide dinitrate
- isosorbide mononitrate
- isosorbide-hydralazine
- Kaletra
- Korlym
- Lexiva
- lopinavir-ritonavir
- Mifeprex
- mifepristone
- Minitran
- nelfinavir
- Nithiodote
- Nitro-bid
- Nitro-dur
- Nitro-time
- nitroglycerin
- nitroglycerin in 5 % dextrose
- Nitrolingual
- Nitromist
- Nitropress
- nitroprusside
- Nitrostat
- Norvir
- Norvir Soft Gelatin
- Reyataz
- riociguat
- ritonavir
- sodium nitrite
- sodium nitrite-sod thiosulfate
- Stribild
- telaprevir
- Victrelis
- Viracept
Contraindicated
- None
Severe
Moderate
- alfuzosin
- Cardura
- Cardura Xl
- Cipro
- Cipro In D5W
- Cipro Xr
- ciprofloxacin
- ciprofloxacin (mixture)
- ciprofloxacin in D5W
- delavirdine
- Dibenzyline
- doxazosin
- dutasteride-tamsulosin
- Flomax
- Jalyn
- Minipress
- phenoxybenzamine
- phentolamine
- prazosin
- Rescriptor
- tamsulosin
- terazosin
- Uroxatral
- Pulmonary veno-occlusive disease
Contraindicated
- Acute myocardial infarction
- Anterior ischemic optic neuropathy
- Esophageal dysmotility
- Hypertrophic cardiomyopathy
- Life-threatening cardiac arrhythmias
Severe
Moderate
- Aortic valve stenosis
- Cerebrovascular accident
- Chronic heart failure
- Fibrosis of corpus cavernosum
- Hearing loss
- Hereditary retinal dystrophy
- Hypotension
- Leukemia
- Multiple myeloma
- Penile angulation
- Peyronie's disease
- Pigmentary retinopathy
- Severe autonomic insufficiency
- Severe uncontrolled hypertension
- Sickle cell disease
- Unstable angina pectoris
LIQREV (sildenafil citrate)
- pulmonary arterial hypertension
- None
- Back pain
- Dizziness
- Dyspepsia
- Edema
- Epistaxis
- Flushing
- Headache disorder
- Nasal congestion
- Nausea
More Frequent
Severe
Less Severe
- Upper respiratory infection
- Visual changes
- Diarrhea
- Dyspnea
- Erythema
- Fever
- Flu-like symptoms
- Insomnia
- Rhinitis
- Sinusitis
- Skin rash
- Urinary tract infection
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Anemia
- Angina
- Anterior ischemic optic neuropathy
- Ataxia
- Atrioventricular block
- Cardiac arrest
- Cardiomyopathy
- Cataracts
- Cerebral thrombosis
- Chest pain
- Chronic heart failure
- Cystitis
- Depression
- Esophagitis
- Exfoliative dermatitis
- Hearing loss
- Hyperglycemia
- Hypernatremia
- Hypertension
- Hypertonia
- Hyperuricemia
- Hypoglycemic disorder
- Hypotension
- Intracerebral hemorrhage
- Leukopenia
- Myocardial ischemia
- Ocular hemorrhage
- Ocular hypertension
- Orthostatic hypotension
- Pain
- Palpitations
- Peripheral edema
- Priapism
- Pulmonary hemorrhage
- Rectal bleeding
- Retinal edema
- Retinal hemorrhage
- Seizure disorder
- Shock
- Syncope
- Tachycardia
- Tendon rupture
- Transient cerebral ischemia
- Uncontrolled diabetes mellitus
- Urinary incontinence
- Ventricular arrhythmias
- Vision loss
- Vitreous detachment
Less Severe
- Abnormal sexual function
- Acute abdominal pain
- Arthritis
- Asthma
- Bone pain
- Bronchitis
- Chills
- Colitis
- Conjunctivitis
- Contact dermatitis
- Cough
- Disorder of ejaculation
- Dream disorder
- Drowsy
- Dry eye
- Dysphagia
- Earache
- Edema of male genital organs
- Facial edema
- Gastritis
- Gastroenteritis
- General weakness
- Gingivitis
- Glossitis
- Gout
- Gynecomastia
- Hematuria
- Hyperhidrosis
- Hypoesthesia
- Hyporeflexia
- Increased sputum
- Increased urinary frequency
- Laryngitis
- Migraine
- Muscle weakness
- Myalgia
- Mydriasis
- Neuralgia
- Nocturia
- Ocular pain
- Orgasm disorder
- Paresthesia
- Peripheral sensory neuropathy
- Pharyngitis
- Photophobia
- Polydipsia
- Pruritus of skin
- Skin photosensitivity
- Skin ulcer
- Stomatitis
- Symptoms of anxiety
- Synovitis
- Tenosynovitis
- Testicular swelling
- Tinnitus
- Transient global amnesia
- Tremor
- Urticaria
- Vertigo
- Vomiting
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Sildenafil (PAH)
Safety and effectiveness not established in pediatric patients age < 1 year.
- 1 Day – 364 Days
- Safety and effectiveness not established in pediatric patients age < 1 year.
Sildenafil
- Severity Level:
2
- Additional Notes: Insufficient human data; consider maternal benefit vs. pot fetal/neonatal risks
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Sildenafil
Limited data suggest minimal excretion, with unknown effect on infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest minimal excretion, with unknown effect on infant |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Sildenafil
Hepatic-Consider dose reduction with hepatic impairment. Renal-Consider dose reduction with severe renal impairment.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Pulmonary arterial hypertension | |
| I27.0 | Primary pulmonary hypertension |
| I27.21 | Secondary pulmonary arterial hypertension |
| 0-9 | A-Z |
|---|---|
| I27.0 | Primary pulmonary hypertension |
| I27.21 | Secondary pulmonary arterial hypertension |
Formulary Reference Tool