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ESTAZOLAM (ESTAZOLAM)
- Insomnia
1 mg tablet
- 1 tablet (1 mg) by oral route once daily at bedtime as needed
2 mg tablet
- 1 tablet (2 mg) by oral route once daily at bedtime as needed
Insomnia
- 1 tablet (1 mg) by oral route once daily at bedtime as needed
- 1 tablet (1 mg) by oral route once daily at bedtime
- 2 tablets (2 mg) by oral route once daily at bedtime
- 1 tablet (2 mg) by oral route once daily at bedtime
- 2 tablets (2 mg) by oral route once daily at bedtime as needed
- 1 tablet (2 mg) by oral route once daily at bedtime as needed
- itraconazole
- ketoconazole
- Onmel
- sodium oxybate
- Sporanox
- Sporanox Pulsepak
- Xyrem
Contraindicated
- clozapine
- Clozaril
- Dehydrated Alcohol
- ethanol (ethyl alcohol)
- ethyl alcohol-herbal drugs
- Fazaclo
- Lydia Pinkham Herbal
- Versacloz
Severe
Moderate
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- buprenorphine-naloxone
- cimetidine
- Diflucan
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- Heartburn Relief
- Noxafil
- posaconazole
- Suboxone
- Tagamet Hb
- Vfend
- Vfend Iv
- voriconazole
- Zubsolv
- Lactating mother
- Pregnancy
Contraindicated
- Alcohol intoxication
Severe
Moderate
- Depression
- Disease of liver
- Drug abuse
- Kidney disease with reduction in GFR
- Myasthenia gravis
- Psychotic disorder
- Severe chronic obstructive pulmonary disease
- Sleep apnea
ESTAZOLAM (ESTAZOLAM)
- Insomnia
- Muscle weakness
- Ataxia
- Dizziness
- Drowsy
- Dyspepsia
- Slurred speech
More Frequent
Severe
Less Severe
- Acute confusion
- Behavioral disorders
- CNS depression
- Diarrhea
- Fatigue
- General weakness
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Accidental fall
- Agranulocytosis
- Anaphylaxis
- Anemia
- Angioedema
- Aplastic anemia
- Apnea
- Coma
- Dehydration
- Depression
- Disease of liver
- Drug-induced psychosis
- Eosinophilia
- Hallucinations
- Hemolytic anemia
- Hepatomegaly
- Hostility
- Hypotension
- Jaundice
- Leukocytosis
- Leukopenia
- Manic disorder
- Memory impairment
- Neutropenic disorder
- Respiratory depression
- Seizure disorder
- Skin rash
- Sleep walking disorder
- Suicidal ideation
- Thrombocytopenic disorder
- Urinary retention
Less Severe
- Aggressive behavior
- Agitation
- Alopecia
- Anorexia
- Aphonia
- Blurred vision
- Bronchial congestion
- Complex sleep behavior
- Concentration difficulty
- Conjunctivitis
- Constipation
- Contact dermatitis
- Cramps
- Delirium
- Depersonalization
- Diplopia
- Disturbance in thinking
- Dream disorder
- Drug dependence
- Dry eye
- Dry skin
- Dysarthria
- Dyspnea
- Dysuria
- Excitement
- Eyes vertical deviation
- Facial edema
- Gastritis
- Gingival pain
- Glossitis
- Headache disorder
- Hiccups
- Hirsutism
- Increased appetite
- Irritability
- Libido changes
- Loss of taste
- Lymphadenopathy
- Menstrual disorder
- Myalgias
- Nausea
- Nervousness
- Nightmares
- Nocturia
- Nystagmus
- Orthostatic hypotension
- Palpitations
- Paranoid disorder
- Polydipsia
- Pruritus of skin
- Rhinorrhea
- Sialorrhea
- Sleep disorder
- Sneezing
- Sore tongue
- Stomatitis
- Swelling of ankles or feet
- Syncope
- Tachycardia
- Tremor
- Urinary incontinence
- Urine discoloration
- Vertigo
- Visual changes
- Visual field defect
- Vomiting
- Weight gain
- Weight loss
- Xerostomia
- Yawning
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Estazolam
Risk of respiratory depression, CNS impairment. No safety and efficacy in pediatrics.
- 1 Day – 18 Years
- Risk of respiratory depression, CNS impairment. No safety and efficacy in pediatrics.
Estazolam
- Severity Level:
X
- Additional Notes:
Contraindicated
Estazolam
Excreted in rat studies;Possible sedation,apnea. long term neuro eff unknown
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Excreted in rat studies;Possible sedation,apnea. long term neuro eff unknown |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Estazolam
Neuro/Psych-Increased risk of cognitive impairment, delirium, falls, fractures, and motor vehicle crashes. If used, limit dose to 0.5-1 mg/day for short term use only.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- Taking estazolam with opioid medications (such as codeine, hydrocodone) may increase your risk of very serious side effects, including death. To lower your risk, your doctor should have you take the smallest dose of estazolam that works, and take it for the shortest possible time. Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up.
| Insomnia | |
| F51.0 | Insomnia not due to a substance or known physiological condition |
| F51.01 | Primary insomnia |
| F51.02 | Adjustment insomnia |
| F51.03 | Paradoxical insomnia |
| F51.04 | Psychophysiologic insomnia |
| F51.05 | Insomnia due to other mental disorder |
| F51.09 | Other insomnia not due to a substance or known physiological condition |
| G47.0 | Insomnia |
| G47.00 | Insomnia, unspecified |
| G47.01 | Insomnia due to medical condition |
| G47.09 | Other insomnia |
| 0-9 | A-Z |
|---|---|
| F51.0 | Insomnia not due to a substance or known physiological condition |
| F51.01 | Primary insomnia |
| F51.02 | Adjustment insomnia |
| F51.03 | Paradoxical insomnia |
| F51.04 | Psychophysiologic insomnia |
| F51.05 | Insomnia due to other mental disorder |
| F51.09 | Other insomnia not due to a substance or known physiological condition |
| G47.0 | Insomnia |
| G47.00 | Insomnia, unspecified |
| G47.01 | Insomnia due to medical condition |
| G47.09 | Other insomnia |
Formulary Reference Tool