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LEVOCETIRIZINE DIHYDROCHLORIDE (LEVOCETIRIZINE DIHYDROCHLORIDE)
- Allergic rhinitis
- Chronic idiopathic urticaria
- Xyzal Tablet
- Xyzal Tab
- Xyzal Oral Solution
- Xyzal Oral Soln
- Levocetirizine Tablet
- Levocetirizine Oral Solution
- Allergy Relief (levocetirizine) Tablet
- 24Hr Allergy Relief Tablet
- By Indication
5 mg tablet
- 1 tablet (5 mg) by oral route once daily in the evening
5 mg tablet
- 1 tablet (5 mg) by oral route once daily in the evening
2.5 mg/5 mL oral solution
- 10 milliliters (5 mg) by oral route once daily in the evening
2.5 mg/5 mL oral solution
- 10 milliliters (5 mg) by oral route once daily in the evening
5 mg tablet
- 1 tablet (5 mg) by oral route once daily in the evening
levocetirizine 5 mg tablet
- 1 tablet (5 mg) by oral route once daily in the evening
2.5 mg/5 mL oral solution
- 10 milliliters (5 mg) by oral route once daily in the evening
levocetirizine 2.5 mg/5 mL oral solution
- 10 milliliters (5 mg) by oral route once daily in the evening
(levocetirizine) 5 mg tablet
- 1 tablet (5 mg) by oral route once daily in the evening
5 mg tablet
- 1 tablet (5 mg) by oral route once daily in the evening
Allergic rhinitis
- 1 tablet (5 mg) by oral route once daily in the evening
- 1 tablet (5 mg) by oral route once daily at bedtime
- 10 milliliters (5 mg) by oral route once daily in the evening
Chronic idiopathic urticaria
- 1 tablet (5 mg) by oral route once daily in the evening
- 1 tablet (5 mg) by oral route once daily at bedtime
- 10 milliliters (5 mg) by oral route once daily in the evening
- None
Contraindicated
- None
Severe
Moderate
- None
- End-stage renal disease
- Hemodialysis with high-flux membrane
Contraindicated
- Benign prostatic hyperplasia with lower urinary tract sx
- Renal disease with moderate to severe impairment
- Urinary retention
Severe
Moderate
- None
LEVOCETIRIZINE DIHYDROCHLORIDE (LEVOCETIRIZINE DIHYDROCHLORIDE)
- Allergic rhinitis
- Chronic idiopathic urticaria
- None
- Cough
- Drowsy
- Epistaxis
- Fatigue
- General weakness
- Pharyngitis
More Frequent
Severe
Less Severe
- None
- Fever
- Xerostomia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acquired dystonia
- Acute generalized exanthematous pustulosis
- Anaphylaxis
- Angioedema
- Cholestasis
- Extrapyramidal disease
- Glomerulonephritis
- Hepatitis
- Seizure disorder
- Suicidal ideation
Less Severe
- Aggressive behavior
- Agitation
- Arthralgias
- Blurred vision
- Constipation
- Depression
- Diarrhea
- Dizziness
- Dysgeusia
- Dyskinesia
- Dyspnea
- Dysuria
- Edema
- Hallucinations
- Hypotension
- Increased appetite
- Insomnia
- Motor tic disorder
- Myalgias
- Myoclonus
- Nausea
- Nightmares
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin rash
- Syncope
- Tachycardia
- Tremor
- Urinary retention
- Urticaria
- Vertigo
- Visual changes
- Vomiting
- Weight gain
Contraindicated
None
Severe Precaution
Levocetirizine
Not indicated age < 6 months.
- 1 Day – 179 Days
- Not indicated age < 6 months.
Management or Monitoring Precaution
None
Levocetirizine
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Levocetirizine
Active enantiomer of cetirizine, cetirizine is excreted. insuff human data
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Active enantiomer of cetirizine, cetirizine is excreted. insuff human data |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Levocetirizine
Renal-Adjust dose for age associated renal impairment. Avoid if CrCL<10 mL/min. Urogenital-Use caution in patients prone to urinary retention; discontinue if retention occurs.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Allergic rhinitis | |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| Chronic idiopathic urticaria | |
| L50.1 | Idiopathic urticaria |
| 0-9 | A-Z |
|---|---|
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| L50.1 | Idiopathic urticaria |
Formulary Reference Tool