TRIAMTERENE-HYDROCHLOROTHIAZID (TRIAMTERENE/HYDROCHLOROTHIAZIDE)
- Edema
- Hypertension
- Triamterene-hydrochlorothiazide Tablet
- Triamterene-hydrochlorothiazide Capsule
- Maxzide-25Mg Tablet
- Maxzide Tablet
- Dyazide Capsule
- By Indication
triamterene 37.5 mg-hydrochlorothiazide 25 mg tablet
- 1 tablet by oral route once daily
triamterene 75 mg-hydrochlorothiazide 50 mg tablet
- 1 tablet by oral route once daily
triamterene 37.5 mg-hydrochlorothiazide 25 mg capsule
- 1 capsule by oral route once daily
Maxzide-25mg 37.5 mg-25 mg tablet
- 1 tablet by oral route once daily
75 mg-50 mg tablet
- 1 tablet by oral route once daily
37.5 mg-25 mg capsule
- 1 capsule by oral route once daily
Edema
- 1 tablet by oral route once daily
- 1 capsule by oral route once daily
- 2 tablets by oral route once daily
- 2 capsules by oral route once daily
Hypertension
- 1 tablet by oral route once daily
- 1 capsule by oral route once daily
- 2 tablets by oral route once daily
- 2 capsules by oral route once daily
- Neoral
- Hecoria
- Gengraf
- dofetilide
- cyclosporine modified
- cyclosporine
- Astagraf Xl
- Prograf
- Sandimmune
- tacrolimus
- Tikosyn
Contraindicated
- Nutrilyte Ii
- Oral Saline Laxative
- Osmoprep
- Pedialyte
- Pediatric Electrolyte
- pediatric multivit #18-iron-FA
- PEG 3350-bowel 2,two part prep
- Phosphate Laxative
- pot & sod citrate-citric acid
- potassium
- potassium bicarb & chloride
- potassium bicarb-citric acid
- potassium chlorid-D5-0.45%NaCl
- potassium chloride
- potassium chloride in 0.9%NaCl
- Nano Vm T/f
- methenamine mand-sod biphos
- Medi-lyte
- Lithobid
- lithium citrate
- lithium carbonate
- Klor-con/ef
- Klor-con M20
- Klor-con M15
- Klor-con M10
- Klor-con 10
- Klor-con
- Kaochlor
- K-tab
- K-effervescent
- Inspra
- Hyperlyte Cr
- Fleet Pediatric
- Fleet Enema Extra
- Fleet Enema
- eplerenone
- Enema Disposable
- Enema
- Effer-k
- DM-GG-potassium citrate
- Disposable Enema
- Cytra-k
- Cytra-3
- Cytra K Crystals
- Curad Enema
- Cerasport Ex1
- Cerasport
- Ceraors 75
- Ceralyte-70
- Alka-seltzer Gold
- potassium chloride in D5W
- potassium chloride in LR-D5
- potassium chloride-0.45 % NaCl
- potassium chloride-D5-0.2%NaCl
- potassium chloride-D5-0.3%NaCl
- potassium chloride-D5-0.9%NaCl
- potassium citrate
- potassium citrate-citric acid
- potassium Cl-calcium phos-mag
- potassium gluconate
- potassium phosphate dibasic
- Preparation Cleansing
- Ready-to-use Enema
- Reclast
- sod & pot chlorid-sod cit-rice
- sod phos mono-sod phos dibasic
- sodium & potassium bicarbonate
- sodium Cl-potassium chloride
- sodium phosphates
- sodium-K+-mag-Ca-chlor-acetate
- sodium-potas-chloride-dextrose
- Sorbutuss
- Suclear
- Taron-crystals
- Theralith Xr
- Thermotabs
- Tpn Electrolytes
- Tpn Electrolytes Ii
- Tricitrates
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
- Uroqid-acid No.2
- vit B6-mag cit & ox-potass cit
- zoledronic acid
- zoledronic acid-mannitol-water
- Zometa
Severe
Moderate
- Novolin R
- Novolog
- Novolog Flexpen
- Novolog Mix 70-30
- Novolog Mix 70-30 Flexpen
- Novolog Penfill
- NPH insulin human recomb
- Ocella
- olmesartan
- olmesartan-amlodipin-hcthiazid
- olmesartan-hydrochlorothiazide
- oxaprozin
- Pennsaid
- perindopril erbumine
- pioglitazone-glimepiride
- piroxicam
- Ponstel
- Novolin N
- Novolin 70/30
- Neoprofen (ibuprofen Lysn)(pf)
- nateglinide
- naproxen-pseudoephedrine
- naproxen-esomeprazole
- naproxen sodium
- naproxen
- Naprosyn
- Naprelan Cr
- Nalfon
- nabumetone
- Motrin Pm
- Motrin Ib
- moexipril-hydrochlorothiazide
- moexipril
- Mobic
- miglitol
- Midol (naproxen)
- Micardis Hct
- Micardis
- meloxicam
- mefenamic acid
- Mediproxen
- Medi-profen
- Mavik
- Lotrel
- Lotensin
- losartan-hydrochlorothiazide
- losartan
- Loryna (28)
- lisinopril-hydrochlorothiazide
- lisinopril
- Levemir Flexpen
- Levemir
- Lantus Solostar
- Lantus
- Lanoxin Pediatric
- Lanoxin
- ketorolac
- ketoprofen
- irbesartan-hydrochlorothiazide
- irbesartan
- insulin regular human
- insulin regular hum U-500 conc
- insulin NPH and regular human
- insulin lispro protam-lispro
- insulin lispro
- insulin glulisine
- insulin glargine
- insulin detemir
- insulin aspart
- insulin asp prt-insulin aspart
- Infants Profenib
- Infants Ibu-drops
- Infant's Motrin
- Infant's Medi-profen
- Infant's Ibuprofen
- indomethacin sodium
- indomethacin
- Indocin
- ibuprofen-phenylephrine HCl
- ibuprofen-oxycodone
- ibuprofen-famotidine
- ibuprofen-diphenhydramine HCl
- ibuprofen-diphenhydramine
- Ibuprofen Pm
- ibuprofen lysine (PF)
- Ibuprofen Jr Strength
- Ibuprofen Ib
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Cold
- ibuprofen
- Ibudone
- Ibu-drops
- I-prin
- Hyzaar
- hydrocodone-ibuprofen
- Humulin R U-500 "Concentrated"
- Humulin R
- Humulin N Kwikpen
- Humulin N
- Humulin 70/30
- Humalog Mix 75-25 Kwikpen
- Humalog Mix 75-25
- Humalog Mix 50-50 Kwikpen
- Humalog Mix 50-50
- Humalog Kwikpen
- Humalog
- Glyset
- Glynase
- glyburide-metformin
- glyburide micronized
- glyburide
- Glucovance
- Glucotrol Xl
- Glucotrol
- glipizide-metformin
- glipizide
- glimepiride
- Gianvi (28)
- fosinopril-hydrochlorothiazide
- fosinopril
- flurbiprofen
- Flector
- Flanax
- fenoprofen
- Feldene
- Exforge Hct
- Exforge
- etodolac
- eprosartan-hydrochlorothiazide
- eprosartan
- Epaned
- enalaprilat
- enalapril-hydrochlorothiazide
- enalapril maleate
- Edarbyclor
- Edarbi
- Ec-naprosyn
- Duexis
- Duetact
- drospirenone-ethinyl estradiol
- drospirenone-estradiol
- drospirenone-e.estradiol-lm.FA
- Diovan Hct
- digoxin
- Digox
- diclofenac-misoprostol
- diclofenac submicronized
- diclofenac sodium
- diclofenac potassium
- diclofenac epolamine
- diazoxide
- Diabeta
- Daypro
- Cozaar
- colestipol
- Colestid Flavored
- Colestid
- Cold-sinus Relief
- Cold & Sinus Pain Relief
- cholestyramine-aspartame
- Cholestyramine Light
- cholestyramine (with sugar)
- chlorphen-pseudoeph-ibuprofen
- chlorphen-phenyleph-ibuprofen
- Children's Profen Ib
- Children's Motrin
- Children's Medi-profen
- Children's Ibuprofen
- Children's Ibu-drops
- Children's Advil
- Child Ibuprofen
- celecoxib
- Celebrex
- Cataflam
- captopril-hydrochlorothiazide
- captopril
- candesartan-hydrochlorothiazid
- candesartan
- Cambia
- Caldolor
- Beyaz
- Benicar Hct
- Benicar
- benazepril-hydrochlorothiazide
- benazepril
- Azor
- azilsartan medoxomil
- azilsartan med-chlorthalidone
- Avapro
- Avalide
- Atacand Hct
- Atacand
- Arthrotec 50
- Apidra Solostar
- Apidra
- Ansaid
- Angeliq
- Anaprox Ds
- Anaprox
- amlodipine-valsartan-hcthiazid
- amlodipine-valsartan
- amlodipine-olmesartan
- amlodipine-benazepril
- Amaryl
- Altace
- All Day Relief
- All Day Pain Relief Sinus & Co
- All Day Pain Relief
- Aleve-d Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve Sinus & Headache
- Aleve Cold & Sinus
- Aleve
- Advil Pm Liqui-gels
- Advil Pm
- Advil Migraine
- Advil Liqui-gel
- Advil Congestion Relief
- Advil Cold & Sinus
- Advil Allergy-congestion Rlf
- Advil Allergy Sinus
- Advil
- Aceon
- Accuretic
- Accupril
- acarbose
- Precose
- Prevalite
- Prinivil
- Proglycem
- Provil
- pseudoephedrine-ibuprofen
- Questran
- Questran Light
- quinapril
- quinapril-hydrochlorothiazide
- ramipril
- Reprexain
- Safyral
- Sinus & Cold-d
- Solaraze
- Sprix
- Starlix
- sulindac
- Syeda
- Tarka
- telmisartan
- telmisartan-amlodipine
- telmisartan-hydrochlorothiazid
- Teveten
- Teveten Hct
- tolazamide
- tolbutamide
- tolmetin
- trandolapril
- trandolapril-verapamil
- Tribenzor
- Twynsta
- Uniretic
- Univasc
- valsartan-hydrochlorothiazide
- Vaseretic
- Vasotec
- Vestura (28)
- Vicoprofen
- Vimovo
- Voltaren-xr
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Yasmin (28)
- Yaz 28
- Zarah
- Zestoretic
- Zestril
- Zipsor
- Zorvolex
- Anuria
- Hyperkalemia
- Pregnancy
- Severe hepatic disease
- Severe renal impairment
Contraindicated
- Acidosis
- Acute pancreatitis
- Azotemia
- Dehydration
- Gout
- Hepatic failure
- Hyperuricemia
- Hypochloremic alkalosis
- Hypokalemia
- Hypomagnesemia
- Hyponatremia
- Hypovolemia
- Kidney disease with reduction in GFR
- Kidney stone
- Neonatal hyperbilirubinemia
- Secondary angle-closure glaucoma
Severe
Moderate
- Basal cell carcinoma of skin
- Diabetes mellitus
- Disease of liver
- Folic acid deficient megaloblastic anemia
- Hypercalcemia
- Hypercholesterolemia
- Hyperparathyroidism
- Hyperuricemia
- Squamous cell carcinoma of skin
- Sympathectomy
- Systemic lupus erythematosus
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
TRIAMTERENE-HYDROCHLOROTHIAZID (TRIAMTERENE/HYDROCHLOROTHIAZIDE)
- Edema
- Hypertension
- Hypochloremic alkalosis
- Hypokalemia
- Hyponatremia
- Hypotension
- None
More Frequent
Severe
Less Severe
- Hyperglycemia
- Hyperkalemia
- Hypomagnesemia
- Kidney disease with reduction in GFR
- Abdominal pain with cramps
- Abnormal sexual function
- Anorexia
- Diarrhea
- Dizziness
- Fatigue
- Headache disorder
- Hyponatremia
- Nausea
- Orthostatic hypotension
- Skin photosensitivity
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute pancreatitis
- Acute renal failure
- Agranulocytosis
- Anaphylaxis
- Aplastic anemia
- Erythema multiforme
- Exfoliative dermatitis
- Gout
- Hemolytic anemia
- Hepatitis
- Hypercalcemia
- Hyperparathyroidism
- Hypersensitivity angiitis
- Hypersensitivity drug reaction
- Hyperuricemia
- Interstitial nephritis
- Interstitial pneumonitis
- Jaundice
- Kidney stone
- Leukopenia
- Megaloblastic anemia
- Metabolic acidosis
- Myopia
- Neutropenic disorder
- Obstructive hyperbilirubinemia
- Purpura
- Secondary angle-closure glaucoma
- Skin rash
- Squamous cell carcinoma of skin
- Stevens-johnson syndrome
- Systemic lupus erythematosus
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Vasculitis
Less Severe
- Basal cell carcinoma of skin
- Blurred vision
- Constipation
- Diarrhea
- Erectile dysfunction
- Fatigue
- Fever
- Gastrointestinal irritation
- General weakness
- Headache disorder
- Hypercholesterolemia
- Hypertriglyceridemia
- Hyperuricemia
- Muscle spasm
- Nausea and vomiting
- Nervousness
- Paresthesia
- Sialoadenitis
- Skin rash
- Urticaria
- Vertigo
- Xanthopsia
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Hydrochlorothiazide
- Severity Level:
B
- Additional Notes: Not recommended in pre-eclampsia and other pregnancy-induced hypertension.
Triamterene
- Severity Level:
1
- Additional Notes: Fda category c. quadruples risk of cardiovascular defects and oral cleft.
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Hydrochlorothiazide
Limited amounts excreted with no known adverse effects in infant.
Insufficient human data available; excreted in animal studies
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited amounts excreted with no known adverse effects in infant. |
Triamterene
Limited amounts excreted with no known adverse effects in infant.
Insufficient human data available; excreted in animal studies
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available; excreted in animal studies |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Hydrochlorothiazide
Cardiovascular-Increased sensitivity to effects on blood pressure. Metabolic-More likely to develop hypokalemia, hypomagnesemia, or hyponatremia. Endocrine-May exacerbate SIADH. May worsen glucose control in patients with diabetes. Renal-Not effective with CrCL < 30mL/min.
Renal-Increased risk for hyperkalemia and hyponatremia in patients with severe renal impairment due to potassium sparing effects. May increase risk of kidney injury Stages IV and V CKD. Avoid with CrCl <30 mL/min.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | N | Y | N | N | Y |
BEERS: Y HEDIS: N STOPP: Y
Triamterene
Cardiovascular-Increased sensitivity to effects on blood pressure. Metabolic-More likely to develop hypokalemia, hypomagnesemia, or hyponatremia. Endocrine-May exacerbate SIADH. May worsen glucose control in patients with diabetes. Renal-Not effective with CrCL < 30mL/min.
Renal-Increased risk for hyperkalemia and hyponatremia in patients with severe renal impairment due to potassium sparing effects. May increase risk of kidney injury Stages IV and V CKD. Avoid with CrCl <30 mL/min.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- This medication can raise your body's potassium levels. The risk for this is higher for people with diabetes or kidney disease, older adults, or during severe illness. High potassium levels can cause serious (rarely fatal) side effects. Tell your doctor right away if you have any of these serious side effects: muscle weakness, slow/irregular heartbeat.
Edema | |
R60 | Edema, not elsewhere classified |
R60.0 | Localized edema |
R60.1 | Generalized edema |
R60.9 | Edema, unspecified |
Hypertension | |
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |
0-9 | A-Z |
---|---|
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |
R60 | Edema, not elsewhere classified |
R60.0 | Localized edema |
R60.1 | Generalized edema |
R60.9 | Edema, unspecified |