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DESFLURANE (desflurane)
- Administration of general anesthesia
100 % inhalation liquid
- Dosage information is not available
100 % inhalation liquid
- Dosage information is not available
- None
Contraindicated
- 12 Hour Nasal Relief Spray
- 12 Hour Nasal Spray
- abobotulinumtoxinA
- Acta-tabs Pe
- Adderall
- Adderall Xr
- Adipex-p
- Adrenalin
- Adult Robitussin M-s Cold
- Adult Robitussin Night M-s Cld
- Adult Robitussin Peak Cold M-s
- Adult Tussin Multi-symp Cold
- Advair Diskus
- Advair Hfa
- Advil Allergy-congestion Rlf
- Advil Congestion Relief
- Afrin (oxymetazoline)
- Afrin Sinus
- Afrin Sinus No Drip
- Ala-hist Dm
- Ala-hist Pe
- albuterol sulfate
- Aldex D
- Aldex-ct
- Alka-seltzer Plus C/c(pe,dm)
- Alka-seltzer Plus Cold (pe)
- Alka-seltzer Plus Cold/cough
- Alka-seltzer Plus Day
- Alka-seltzer Plus Day-night
- Alka-seltzer Plus Flu
- Alka-seltzer Plus Night
- Alka-seltzer Plus Sin-allg-cgh
- Alka-seltzer Plus Sinus-cough
- Allergy M-s Nighttime
- Allergy Multi-symptom
- Allergy Plus Severe Sinus Ha
- Allergy Relief Multi-symptom
- Allergy Relief(chlorphen-acet)
- Allergy Relief-sinus Headache
- Allergy Sinus Headache
- Allergy Sinus Pe
- Allergy-d
- Allergy-sinus
- Altipres
- Altipres Pediatric
- Altipres-b
- Ambi 10Peh-4Cpm
- Ambi 10Peh-4Cpm-20Dm
- amikacin
- Amphetamine Salt Combo
- Anectine
- Anefrin
- Anoro Ellipta
- Ap-hist Dm
- Arcapta Neohaler
- arformoterol
- Asthmanefrin Refill
- Asthmanefrin Starter Kit
- atracurium
- Baciim
- bacitracin
- Balamine Dm
- benzphetamine
- Bethkis
- Bio T Pres
- Bio T Pres Pediatric
- Bio T Pres-b
- Bio-b Kids
- Bio-s-pres Dx
- Biobron Dx
- Biobron Sf
- Biocotron-d
- Biodesp Dm
- Biogil
- Biogtuss Nf
- Bionatuss Dxp
- Bontril Pdm
- Botox
- Botox Cosmetic
- Breo Ellipta
- Brohist D
- brompheniramin-phenylephrin-DM
- brompheniramine-PE-chlophedian
- brompheniramine-PE-codeine
- brompheniramine-phenylephrine
- Bronchial Asthma Relief
- Bronchial Mist
- Bronchial Mist Refill
- Broncotron Ped
- Bronkaid Dual Action
- Bronkids
- Brontuss Sf
- Brovana
- Brovex Peb
- Brovex Peb Dm
- budesonide-formoterol
- bupivacaine-epinephrine
- bupivacaine-epinephrine (PF)
- bupivacaine-epinephrine bitart
- Capcof
- Carbaphen Ch
- Carbaphen Ped Ch
- Cardec
- Cardec Dm
- Ccp Caffeine Free
- Centergy
- Centergy Dm
- Chest Congestion Relief Pe
- Chest-sinus Congestion Relief
- Child Delsym Cough+cold
- Child Dometuss-da
- Child Mucinex Congestion-cough
- Child Mucinex Stuffy Nose-cold
- Child Multi-symptom Cold/cough
- Child Wal-tap Cold-allergy
- Child's Benadryl-d Allergy-sin
- Child's Mucus Relief M-s Cold
- Children Night Time Cold-cough
- Children's Cold & Allergy
- Children's Cold & Cough
- Children's Cold & Cough Dm
- Children's Cold-cough-sore
- Children's Dibromm Cold & Alle
- Children's Dibromm Dm Cold & C
- Children's Dimetapp Cold &Flu
- Children's Flu Relief
- Children's Mucinex Cold-fever
- Children's Mucinex Multi-symp
- Children's Mucinex Night Time
- Children's Plus Flu
- Children's Sudafed Pe Cough
- Children's Sudafed Pe Nasal
- Childrens Plus Cold
- Childs Plus Cold & Allergy
- Childs Triacting Cold & Cough
- chlorcyclizine-phenylephrine
- chlorphen-PE-DM-acetaminophen
- chlorphen-phenyleph-DM-aspirin
- chlorphen-phenyleph-ibuprofen
- chlorphenir-phenylephrn-aspirn
- chlorpheniram-PE-chlophedianol
- chlorpheniramine-PE-codeine
- chlorpheniramine-phenyleph-DM
- chlorpheniramine-phenylephrine
- cisatracurium
- Codituss Dm
- Cold & Allergy
- Cold & Allergy Pe
- Cold & Cough
- Cold & Cough Dm
- Cold & Cough Elixir
- Cold & Flu Severe
- Cold Head Congestion
- Cold Head Congestion Day/nite
- Cold Multi-symptom
- Cold Multi-symptom Day/night
- Cold Multi-symptom Daytime
- Cold Multi-symptom Nighttime
- Cold Relief
- Cold Relief M/s Day/night
- Cold Relief Plus
- Cold Severe Congestion
- Cold-cough Sinus Relief Pe
- Cold-flu Relief
- Cold-flu Relief, Day/night
- Combivent Respimat
- Complete Sinus Relief
- Concerta
- Congest-eze Pe
- Contac Cold-flu Day And Night
- Contac Cold-flu Max Strength
- Cough & Cold
- Cough & Cold Mucus Relief Cf
- Cough & Severe Cold
- cpm-phenyleph-acetaminophen
- Dallergy (chlorcyclizine-pe)
- Dallergy (chlorpheniramine-pe)
- Dallergy (dexbrompheniramn-pe)
- Day Time Pe
- Daytime
- Daytime & Nighttime Cold
- Daytime & Nitetime Sinus
- Daytime Cold & Flu Relief
- Daytime Cold-flu
- Daytime Sinus
- Daytime-nighttime
- Daytime-nighttime Cold-flu
- Daytrana
- Deconex Dmx
- Deconex Ir
- Decorel Forte Plus
- Delsym Cough+cold Daytime
- Delsym Cough+cold Nighttime
- Desgen
- Desgen Dm
- Desoxyn
- Despec
- Despec Eda Cough & Cold Drops
- Despec-dm
- dexbromphen-phenyleph-acetamin
- dexbrompheniramine-phenylep-DM
- dexbrompheniramine-phenyleph
- dexchlorphen-phenyleph-codeine
- dexchlorpheniram-phenylephrine
- Dexedrine Spansule
- dexmethylphenidate
- dextroamphetamine
- dextroamphetamine-amphetamine
- Didrex
- diethylpropion
- Dimaphen (pe)
- Dimaphen Dm
- Dimetapp Cold-allergy (pe)
- Dimetapp Cold-congestion
- Dimetapp Dm Cold-cough (pe)
- diphenhy HCl-PE-DM-acetamin-GG
- diphenhyd-PE-acetaminophen
- diphenhyd-PE-DM-acetaminophen
- diphenhydram-PE-acetaminoph-GG
- diphenhydramine-phenylephrine
- DM-PE-acetam/DM-acetam-doxylam
- dobutamine
- dobutamine in D5W
- Dometuss G
- Dometuss-dmx
- Donatussin Pediatric
- dopamine
- dopamine in D5W
- doxylam-PE-DM-acetaminophen-GG
- doxylam-phenylephrine-acetamin
- doxylamine-PE-DM-acetaminophen
- doxylamine-phenylep-DM-aspirin
- doxylamine-phenylephrine
- Dristan Cold
- Dristan Long Lasting
- Dulera
- Duoneb
- Duravent Dm
- Duravent Pe
- Dysport
- Ed A-hist
- Ed A-hist Dm
- Ed Bron Gp
- Ed Chlorped D
- Effervescent Cold Relief Plus
- Endacof - Dm
- Endacon
- Entex Lq
- Entre-b
- ephedrine sulfate
- ephedrine sulfate-guaifenesin
- ephedrine-guaifenesin
- Ephrine
- epinephrine
- epinephrine (PF)
- epinephrine base (refill)
- epinephrine HCl
- Exactuss
- Fast Acting Nasal
- Fenesin Pe Ir
- Flu & Severe Cold-daytime
- Flu & Severe Cold-nighttime
- Flu & Sore Throat
- Flu & Sore Throat Relief
- Flu Formula Daytime-nighttime
- Flu Relief Therapy Cold-chest
- Flu Relief Therapy Daytime
- Flu Relief Therapy Nighttime
- Flu-severe Cold-cough
- fluticasone-salmeterol
- fluticasone-vilanterol
- Focalin
- Focalin Xr
- Foradil Aerolizer
- formoterol fumarate
- G-p-tuss Dxp
- G-supress Dx
- G-tron Ped
- G-tusicof
- gentamicin
- gentamicin in NaCl (iso-osm)
- gentamicin sulfate (ped) (PF)
- gentamicin sulfate (PF)
- Gilphex Tr
- Giltuss
- Giltuss Pediatric
- Giltuss Tr
- Head Congestion Cold Relief
- Histex Dm
- Histex Pe
- ibuprofen-phenylephrine HCl
- incobotulinumtoxinA
- indacaterol
- Intense Cold & Flu
- ipratropium-albuterol
- isometh-dichloral-acetaminophn
- isomethepten-caf-acetaminophen
- isoproterenol HCl
- Isuprel
- J-max
- levalbuterol HCl
- levalbuterol tartrate
- levmetamfetamine
- Levophed (bitartrate)
- lidocaine-epinephrine
- lidocaine-epinephrine (PF)
- lidocaine-epinephrine bit
- Liquibid D-r
- Liquibid Pd-r
- lisdexamfetamine
- Little Noses
- Lohist Peb Dm
- Lohist-dm
- Lohist-peb
- Long Acting Nasal Spray
- M-end Pe
- Mapap Cold Formula
- Mapap Sinus Max Strength (pe)
- Marcaine-epinephrine
- Marcaine-epinephrine (pf)
- Maxiphen
- Maxiphen Dm
- Maxiphen Dmx
- Medi-phenyl
- Medicidin-d
- Metadate Cd
- Metadate Er
- metaproterenol
- methamphetamine
- Methylin
- methylphenidate
- midodrine
- Migragesic Ida
- mometasone-formoterol
- Mucaphed
- Mucinex Cold & Sinus
- Mucinex Cold-flu & Sore Throat
- Mucinex Fast-max Cold-flu
- Mucinex Fast-max Cold-sinus
- Mucinex Fast-max Congest-cold
- Mucinex Fast-max Congest-cough
- Mucinex Fast-max Nite Cold-flu
- Mucinex Sinus-max Day-night
- Mucinex Sinus-max Pressur-pain
- Mucinex Sinus-max Sev Congest
- Mucus Relief
- Mucus Relief Cold & Sinus
- Mucus Relief Cold-flu-sore Thr
- Mucus Relief D (phenylephrine)
- Mucus Relief Pe
- Mucus Relief Plus
- Mucus Relief Sev Congest-cold
- Mucus Relief Sinus
- Multi-symptom Cold (pe & Cpm)
- Multi-symptom Cold (pe)
- Multi-symptom Cold Daytime
- Multi-symptom Cold Night Time
- Myobloc
- Nasal Decongestant
- Nasal Decongestant (oxymetazl)
- Nasal Decongestant (pe)
- Nasal Four
- Nasal Relief
- Nasal Spray (oxymetazoline)
- Nasal Spray 12 Hour
- Nasal Spray 12 Hour Sinus
- Nasal Spray Extra Moisturizing
- Nasal Spray Long Acting
- Nasal Spray Moisturizing
- Nasal Spray Sinus
- Nasal Spray X-moist
- Nasohist
- Nasohist Dm
- Nasopen Pe
- Neo-synephrine (phenylephrine)
- Neo-synephrine 12 H Spr (oxym)
- neomycin
- Neotuss Plus
- Neotuss-d (improved Formula)
- Night Time Cold
- Nighttime Cough-cold
- Nighttime Sinus
- Nimbex
- No Drip
- No Drip Nasal Relief
- Nodolor
- Nohist-dm
- Nohist-lq
- Non-aspirin Severe Congest M-s
- Non-aspirin Sinus
- Non-drying Sinus
- Non-pseudo Cold Relief
- Non-pseudo Sinus Pain-pressure
- Norel Ad
- Norel Cs
- norepinephrine bitartrate
- Nose Drops
- Nose Drops Extra Strength
- Nose Spray
- Nrs Nasal Relief
- Nu Way
- Nu-copd
- onabotulinumtoxinA
- Original Nasal Spray
- oxymetazoline
- Pain Relief Allergy Sinus
- Pain Relief Cold
- Pain Relief Sinus Pe
- pancuronium
- PE-acetam/doxylamine-PE-acetam
- PE-DM-ASA/doxyla-PE-DM-ASA
- Pediacare Decongestant (pe)
- Pediacare Multi-symptom Cold
- Perforomist
- Phenabid Dm
- Phenagil
- Phenagil Ch
- phendimetrazine tartrate
- pheniramine-phenyleph-acetamin
- phentermine
- phentermine-topiramate
- phenyleph-DM-acetamin-guaifen
- phenylephrine HCl
- phenylephrine-acetaminophen
- phenylephrine-acetaminophen-GG
- phenylephrine-chlophedianol-GG
- phenylephrine-DM
- phenylephrine-DM-acetaminophen
- phenylephrine-DM-guaifenesin
- phenylephrine-guaifenesin
- phenylephrine-pyrilamine
- Poly Hist Forte (doxylamine)
- Poly-hist Dm (thonzylamine)
- Poly-tussin Ac
- polymyxin B sulfate
- Pres Gen
- Pres Gen Pediatric
- Presgen B
- Pressure & Pain
- Primatene Asthma
- Pro-chlo
- Pro-red Ac (w/ Dexchlorphenir)
- Proair Hfa
- Procentra
- Prodrin
- Promethazine Vc
- Promethazine Vc-codeine
- promethazine-phenyleph-codeine
- promethazine-phenylephrine
- Proventil Hfa
- pyrilamine-PE-chlophedianol
- pyrilamine-phenylephrine-DM
- Pyrroxate Cold & Congest
- Qsymia
- Quelicin
- Quillivant Xr
- racepinephrine
- Refenesen Pe
- Regimex
- Rescon-gg
- rimabotulinumtoxinB
- Ritalin
- Ritalin La
- Ritalin Sr
- Robafen Cf
- Robitussin Cold-flu Day
- Robitussin Cough & Cold Cf
- Ru-hist D
- Ru-hist-d (with Pyrilamine)
- Rymed
- Rynex Dm
- Rynex Pe
- S2 Racepinephrine
- salmeterol
- Sensorcaine-mpf/epinephrine
- Sensorcaine/epinephrine
- Serevent Diskus
- Severe Allergy-sinus Headache
- Severe Cold
- Severe Cold (diphen-pe-acetam)
- Severe Cold Multi-symptom
- Severe Cold Pe
- Severe Congestion
- Severe Congestion & Cough Max
- Sinex Ultra Fine Mist 12-hour
- Sinus & Allergy
- Sinus & Allergy Pe
- Sinus Cong & Pain Day-night
- Sinus Congestion & Pain
- Sinus Daytime-nightime
- Sinus Decongestant (pe)
- Sinus Formula Daytime
- Sinus Headache Pe
- Sinus Maximum Strength
- Sinus Nasal Spray
- Sinus Nighttime
- Sinus Pain Relief
- Sinus Relief (non-drowsy)
- Sinus Relief (oxymetazoline)
- Sinutrol Pe
- sodium oxybate
- streptomycin
- succinylcholine chloride
- Sudafed Pe Pressure+pain+cold
- Sudafed Pe Pressure+pain+cough
- Sudogest Pe
- Suphedrine Pe
- Suphedrine Pe Cold & Allergy
- Suphedrine Pe Day-night
- Suphedrine Pe Sinus & Allergy
- Suphedrine Pe Sinus Headache
- Suprenza
- Supress A
- Supress Dx
- Supress-pe
- Symbicort
- terbutaline
- tetrahydrozoline
- Tg 10Peh-380Gfn
- Tg 10Peh-380Gfn-15Dm
- Theraflu Daytime Cold-cough
- Theraflu Flu-sore Throat
- Theraflu Multi-symptom Cold
- Theraflu Nighttime Cold-cough
- thonzylamine-phenyl-chlophed
- thonzylamine-phenylephrine
- thonzylamine-phenylephrine-DM
- Tl-hist Dm
- Tobi
- Tobi Podhaler
- tobramycin
- tobramycin in 0.225 % NaCl
- tobramycin in 0.9 % NaCl
- tobramycin sulfate
- Trexbrom
- Tri-dex Pe
- Triaminic Cold & Cough (pe)
- Triaminic Cold & Cough Nt (pe)
- Triaminic Cold- Allergy Pe
- Trigofen Dm
- triprolidine-phenylephrine
- triprolidine-phenylephrine-DM
- Tusicof
- Tussi Pres-b
- Tussi-pres
- Tussi-pres Pediatric
- Tussin Cf
- Tussin Cf Cough-cold
- Tussin Cf Max
- Tussin Cough-cold-flu
- Tussin Pe
- Tusslin
- Tylenol Cold & Flu Severe
- Tylenol Cold Head Congest Sevr
- Tylenol Cold Multi-sympt Night
- Tylenol Cold Multi-symptom Day
- Tylenol Sinus Congestion Pain
- Tyzine
- umeclidinium-vilanterol
- Vanacof Ape
- Vanacof Dm
- Vanacof Gpe
- Vapor Inhaler
- Vazobid-pd
- Vazotab (pyrilamine)
- vecuronium bromide
- Ventolin Hfa
- Vicks Dayquil
- Vicks Dayquil Cold&Flu Relief
- Vicks Dayquil Severe Cold-flu
- Vicks Dayquil Sinex
- Vicks Dayquil-nyquil
- Vicks Dayquil-nyquil Cold-flu
- Vicks Dayquil-nyquil Severe
- Vicks Nature Fusion
- Vicks Nyquil Severe Cold-flu
- Vicks Nyquil Sinex
- Vicks Sinex 12-hour
- Virdec
- Virdec Dm
- Vospire Er
- Vyvanse
- Wal-dryl Severe Allergy-sinus
- Wal-dryl-d Allergy & Sinus
- Wal-flu Night Severe Cold
- Wal-flu Night Time
- Wal-flu Severe Cold
- Wal-flu Severe Cold-cough
- Wal-four
- Wal-phed Pe
- Wal-phed Pe Cold-cough
- Wal-phed Pe Nighttime Cold
- Wal-phed Pe Severe Cold
- Wal-phed Pe Sinus & Allergy
- Wal-tap
- Wal-tap Dm
- Wal-tussin Cough & Cold Cf
- Xeomin
- Xopenex
- Xopenex Concentrate
- Xopenex Hfa
- Xylocaine-epinephrine
- Xylocaine-mpf/epinephrine
- Xyrem
- Zenzedi
Severe
Moderate
- None
- Malignant hyperthermia
Contraindicated
- Disease of liver
- Duchenne muscular dystrophy
- Hepatic cirrhosis
- Hyperkalemia
- Neuromuscular disease
- Viral hepatitis B
- Viral hepatitis C
Severe
Moderate
- Congenital long QT syndrome
- Coronary artery disease
- Familial periodic paralysis
DESFLURANE (desflurane)
- Administration of general anesthesia
- Apnea
- Increased bronchial secretions
- Laryngismus
- Pharyngitis
- Cough
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- Abnormal ECG
- Bradycardia
- Hypertension
- Hypotension
- Tachycardia
- Dyspnea
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute hepatic failure
- Acute myocardial infarction
- Acute pancreatitis
- Acute respiratory insufficiency
- Agitation
- Asthma
- Atrial fibrillation
- Bronchospastic pulmonary disease
- Cardiac arrest
- Cholestasis
- Encephalopathy
- Heart failure
- Hemorrhage
- Hepatic necrosis
- Hepatitis
- Hyperbilirubinemia
- Hyperkalemia
- Hypokalemia
- Hypoxia
- Increased risk of bleeding due to coagulation disorder
- Jaundice
- Malignant hyperthermia
- Metabolic acidosis
- Myocardial ischemia
- Prolonged QT interval
- Rhabdomyolysis
- Seizure disorder
- Shock
- Torsades de pointes
- Urticaria
- Vasodilation of blood vessels
- Ventricular arrhythmias
- Ventricular bigeminy
Less Severe
- Acute abdominal pain
- Conjunctival hyperemia
- Conjunctivitis
- Dizziness
- Erythema
- Fever
- General weakness
- Headache disorder
- Malaise
- Myalgias
- Palpitations
- Pruritus of skin
- Scleral icterus
- Sialorrhea
- Transient blindness
Contraindicated
None
Severe Precaution
Desflurane
Contraindicated for induction of anesthesia in children. Avoid use longer than 3 hours. Risk of laryngospasm, cough, and secretions. Particular caution with asthma or recent upper airway infection. Risk of postoperative agitation.
Contraindicated for induction of anesthesia in children. Risk of laryngospasm, cough, and secretions. Particular caution with asthma or recent upper airway infection. Risk of postoperative agitation. Unknown risk of long-term cognitive deficits with duration of use exceeding 3 hours.
- 1 Day – 3 Years
- Contraindicated for induction of anesthesia in children. Avoid use longer than 3 hours. Risk of laryngospasm, cough, and secretions. Particular caution with asthma or recent upper airway infection. Risk of postoperative agitation.
- Contraindicated for induction of anesthesia in children. Risk of laryngospasm, cough, and secretions. Particular caution with asthma or recent upper airway infection. Risk of postoperative agitation. Unknown risk of long-term cognitive deficits with duration of use exceeding 3 hours.
- 3 Years – 16 Years
- Contraindicated for induction of anesthesia in children. Avoid use longer than 3 hours. Risk of laryngospasm, cough, and secretions. Particular caution with asthma or recent upper airway infection. Risk of postoperative agitation.
- Contraindicated for induction of anesthesia in children. Risk of laryngospasm, cough, and secretions. Particular caution with asthma or recent upper airway infection. Risk of postoperative agitation. Unknown risk of long-term cognitive deficits with duration of use exceeding 3 hours.
Management or Monitoring Precaution
None
Desflurane
- Severity Level:
2
- Additional Notes: Insufficient human data; animal data sug dev tox
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Desflurane
Low molecular wt,may be excreted; short t 1/2, infant exposure likely minimal
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Low molecular wt,may be excreted; short t 1/2, infant exposure likely minimal |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Desflurane
General-The minimum alveolar concentration (MAC) of desflurane decreases with increasing patient age. The average MAC in a 70 year old patient is two-thirds the MAC for a 20 year old. Adjust dose in the elderly accordingly.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
Formulary Reference Tool