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CILOSTAZOL (CILOSTAZOL)
- Intermittent claudication
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day 1/2 hour before or 2 hours after breakfast and dinner
50 mg tablet
- 1 tablet (50 mg) by oral route 2 times per day 1/2 hour before or 2 hours after breakfast and dinner
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day 1/2 hour before or 2 hours after breakfast and dinner
50 mg tablet
- 1 tablet (50 mg) by oral route 2 times per day 1/2 hour before or 2 hours after breakfast and dinner
Intermittent claudication
- 1 tablet (50 mg) by oral route 2 times per day 1/2 hour before or 2 hours after breakfast and dinner
- 2 tablets (100 mg) by oral route 2 times per day 1/2 hour beforeor 2 hours after breakfast and dinner
- 1 tablet (100 mg) by oral route 2 times per day 1/2 hour before or 2 hours after breakfast and dinner
- amiodarone
- amiodarone in dextrose,iso-osm
- artemether-lumefantrine
- Coartem
- Cordarone
- disopyramide
- droperidol
- Mifeprex
- mifepristone
- Nexterone
- Norpace
- Norpace Cr
- Orap
- Pacerone
- pimozide
Contraindicated
- apixaban
- Aptivus
- Avelox
- Avelox Abc Pack
- Avelox In Nacl (iso-osmotic)
- Caprelsa
- dofetilide
- Eliquis
- Fareston
- Geodon
- Invega
- Invega Sustenna
- Kaletra
- lopinavir-ritonavir
- moxifloxacin
- moxifloxacin in NaCl (iso-osm)
- paliperidone
- paliperidone palmitate
- propafenone
- Qualaquin
- quetiapine
- quinine sulfate
- rivaroxaban
- Rythmol
- Seroquel
- Seroquel Xr
- tetrabenazine
- thioridazine
- Tikosyn
- tipranavir
- toremifene
- vandetanib
- Xarelto
- Xenazine
- ziprasidone HCl
- ziprasidone mesylate
Severe
Moderate
- Activase
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- alfuzosin
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- alteplase
- Anaprox
- Anaprox Ds
- Ansaid
- Anzemet
- Apokyn
- apomorphine
- Arixtra
- Arthrotec 50
- Brintellix
- Brisdelle
- Caldolor
- Cambia
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Cataflam
- Celexa
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- citalopram
- clozapine
- Clozaril
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Complera
- Coumadin
- Cymbalta
- dalteparin (porcine)
- dasatinib
- Daypro
- desvenlafaxine
- desvenlafaxine fumarate
- desvenlafaxine succinate
- diclofenac epolamine
- diclofenac potassium
- diclofenac sodium
- diclofenac submicronized
- diclofenac-misoprostol
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- dolasetron
- Duexis
- duloxetine
- Ec-naprosyn
- Edurant
- Effexor Xr
- Elmiron
- emtricitab-rilpivirine-tenofov
- enoxaparin
- eptifibatide
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- escitalopram oxalate
- esomeprazole magnesium
- esomeprazole sodium
- esomeprazole strontium
- etodolac
- Fazaclo
- Feldene
- fenoprofen
- Fetzima
- First-omeprazole
- Flanax
- Flector
- fluoxetine
- flurbiprofen
- fluvoxamine
- fondaparinux
- Fragmin
- heparin (porcine)
- heparin (porcine) in D5W
- heparin(porcine) in 0.45% NaCl
- heparin, porcine (PF)
- hydrocodone-ibuprofen
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- Integrilin
- Jantoven
- Juxtapid
- ketoprofen
- ketorolac
- Khedezla
- lapatinib
- lepirudin
- levomilnacipran
- Lexapro
- lomitapide
- Lovenox
- Luvox Cr
- Matzim La
- Medi-profen
- Mediproxen
- mefenamic acid
- meloxicam
- Midol (naproxen)
- milnacipran
- Mobic
- Motrin Ib
- Motrin Pm
- nabumetone
- Nalfon
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- Neoprofen (ibuprofen Lysn)(pf)
- Nexium
- Nexium Iv
- Nexium Packet
- norfloxacin
- Noroxin
- olanzapine-fluoxetine
- Omeclamox-pak
- omeprazole
- omeprazole magnesium
- Omeprazole+syrspend Sf Alka
- omeprazole-clarith-amoxicillin
- omeprazole-sodium bicarbonate
- oxaprozin
- paroxetine HCl
- paroxetine mesylate
- pasireotide
- Paxil
- Paxil Cr
- pazopanib
- Pennsaid
- pentosan polysulfate sodium
- Pexeva
- piroxicam
- Ponstel
- Prilosec
- Prilosec Otc
- Pristiq
- Provil
- Prozac
- Prozac Weekly
- pseudoephedrine-ibuprofen
- Refludan
- Reprexain
- Retavase
- reteplase
- rilpivirine
- Sarafem
- Savella
- sertraline
- Signifor
- Sinus & Cold-d
- Solaraze
- Sprix
- Sprycel
- sulindac
- Symbyax
- Taztia Xt
- tenecteplase
- Tiazac
- Tnkase
- tolmetin
- Tykerb
- Uroxatral
- venlafaxine
- Versacloz
- Vicoprofen
- Viibryd
- vilazodone
- Vimovo
- Voltaren-xr
- vortioxetine
- Votrient
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- warfarin
- Zegerid
- Zegerid Otc
- Zipsor
- Zoloft
- Zorvolex
- Chronic heart failure
- Congenital long QT syndrome
- Hemorrhage
- Torsades de pointes
Contraindicated
- Leukopenia
- Prolonged QT interval
- Thrombocytopenic disorder
- Tobacco smoker
Severe
Moderate
- Angina
- Left ventricular outflow obstruction
- Tachyarrhythmia
CILOSTAZOL (CILOSTAZOL)
- Intermittent claudication
- Infection
- Diarrhea
- Dizziness
- Headache disorder
- Loose stools
- Palpitations
- Peripheral edema
- Rhinitis
More Frequent
Severe
Less Severe
- Duodenal ulcer
- Epistaxis
- Ocular hemorrhage
- Peptic ulcer
- Purpura
- Rectal bleeding
- Retinal hemorrhage
- Sinusitis
- Syncope
- Tachycardia
- Tongue swelling
- Acute abdominal pain
- Arthralgias
- Back pain
- Bone pain
- Colitis
- Cough
- Dyspepsia
- Edema
- Esophagitis
- Fever
- Flatulence
- Gastritis
- Myalgias
- Nausea
- Orthostatic hypotension
- Pharyngitis
- Vertigo
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Abnormal vaginal bleeding
- Acute eruptions of skin
- Agranulocytosis
- Anaphylaxis
- Anemia
- Angina
- Angioedema
- Aplastic anemia
- Atrial fibrillation
- Cerebral ischemia
- Cerebrovascular accident
- Chest pain
- Gastrointestinal hemorrhage
- Granulocytopenic disorder
- Hematuria
- Hemoptysis
- Hemorrhage
- Hyperglycemia
- Hypertension
- Hyperuricemia
- Hypotension
- Increased risk of bleeding
- Interstitial pneumonitis
- Intracerebral hemorrhage
- Jaundice
- Left ventricular outflow obstruction
- Leukopenia
- Neck stiffness
- Pancytopenia
- Paresthesia
- Prolonged QT interval
- Pruritus of skin
- Pulmonary hemorrhage
- Skin rash
- Stevens-johnson syndrome
- Subdural intracranial hemorrhage
- Thrombocytopenic disorder
- Torsades de pointes
- Ventricular tachycardia
Less Severe
- Anorexia
- Black tarry stools
- Bursitis
- Cramps in legs
- Ecchymosis
- Flushing
- Furunculosis
- General weakness
- Increased urinary frequency
- Insomnia
- Malaise
- Proteinuria
- Skin inflammation
- Tinnitus
- Urticaria
- Varicose veins
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Cilostazol
No safety and efficacy established.
- 1 Day – 18 Years
- No safety and efficacy established.
Cilostazol
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Cilostazol
None
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Cilostazol
Cardiovascular-Avoid in patients with heart failure of any severity due to cilostazol-induced fluid retention.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | N | N | N |
BEERS: Y HEDIS: N STOPP: N
No Known Risk
None
- Medications similar to cilostazol have caused serious (possibly fatal) problems in people with a certain type of heart disease (heart failure). Therefore, do not use cilostazol if you have heart failure.
| Intermittent claudication | |
| I70.21 | Atherosclerosis of native arteries of extremities with intermittent claudication |
| I70.211 | Atherosclerosis of native arteries of extremities with intermittent claudication, right leg |
| I70.212 | Atherosclerosis of native arteries of extremities with intermittent claudication, left leg |
| I70.213 | Atherosclerosis of native arteries of extremities with intermittent claudication, bilateral legs |
| I70.218 | Atherosclerosis of native arteries of extremities with intermittent claudication, other extremity |
| I70.219 | Atherosclerosis of native arteries of extremities with intermittent claudication, unspecified extremity |
| I70.31 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication |
| I70.311 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.312 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.313 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.318 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.319 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.41 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication |
| I70.411 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.412 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.413 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.418 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.419 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.51 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities intermittent claudication |
| I70.511 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.512 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.513 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.518 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.519 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.61 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication |
| I70.611 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.612 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.613 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.618 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.619 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.71 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication |
| I70.711 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.712 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.713 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.718 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.719 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| 0-9 | A-Z |
|---|---|
| I70.21 | Atherosclerosis of native arteries of extremities with intermittent claudication |
| I70.211 | Atherosclerosis of native arteries of extremities with intermittent claudication, right leg |
| I70.212 | Atherosclerosis of native arteries of extremities with intermittent claudication, left leg |
| I70.213 | Atherosclerosis of native arteries of extremities with intermittent claudication, bilateral legs |
| I70.218 | Atherosclerosis of native arteries of extremities with intermittent claudication, other extremity |
| I70.219 | Atherosclerosis of native arteries of extremities with intermittent claudication, unspecified extremity |
| I70.31 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication |
| I70.311 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.312 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.313 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.318 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.319 | Atherosclerosis of unspecified type of bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.41 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication |
| I70.411 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.412 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.413 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.418 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.419 | Atherosclerosis of autologous vein bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.51 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities intermittent claudication |
| I70.511 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.512 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.513 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.518 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.519 | Atherosclerosis of nonautologous biological bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.61 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication |
| I70.611 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.612 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.613 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.618 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.619 | Atherosclerosis of nonbiological bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
| I70.71 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication |
| I70.711 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, right leg |
| I70.712 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, left leg |
| I70.713 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, bilateral legs |
| I70.718 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, other extremity |
| I70.719 | Atherosclerosis of other type of bypass graft(s) of the extremities with intermittent claudication, unspecified extremity |
Formulary Reference Tool