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AMIODARONE HCL (AMIODARONE HCL)
- Life-threatening ventricular tachycardia
- Ventricular fibrillation
- Prevention of ventricular fibrillation
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day
200 mg tablet
- 1 tablet (200 mg) by oral route once daily
400 mg tablet
- 1 tablet (400 mg) by oral route once daily
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day
200 mg tablet
- 1 tablet (200 mg) by oral route once daily
400 mg tablet
- 1 tablet (400 mg) by oral route once daily
amiodarone 100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day
amiodarone 200 mg tablet
- 1 tablet (200 mg) by oral route once daily
amiodarone 400 mg tablet
- 1 tablet (400 mg) by oral route once daily
Cardioversion of atrial fibrillation
- 1 tablet (200 mg) by oral route once daily
Prevention of recurrent atrial fibrillation
- 1 tablet (200 mg) by oral route once daily
Prevention of ventricular fibrillation
- 1 tablet (100 mg) by oral route 2 times per day
- 2 tablets (200 mg) by oral route once daily
- 1 tablet (200 mg) by oral route 2 times per day
- 1 tablet (200 mg) by oral route once daily
- 2 tablets (400 mg) by oral route once daily
- 1 tablet (400 mg) by oral route once daily
Ventricular fibrillation
- 1 tablet (100 mg) by oral route 2 times per day
- 1 tablet (100 mg) by oral route once daily
- 2 tablets (200 mg) by oral route once daily
- 1 tablet (200 mg) by oral route 2 times per day
- 2 tablets (200 mg) by oral route 2 times per day
- 2 tablets (400 mg) by oral route once daily
- 1 tablet (400 mg) by oral route once daily
- agalsidase beta
- Apokyn
- apomorphine
- Aptivus
- arsenic trioxide
- artemether-lumefantrine
- bedaquiline
- Betapace
- Betapace Af
- Caprelsa
- Celexa
- chloroquine phosphate
- chlorpromazine
- citalopram
- Coartem
- Corvert
- Crixivan
- dasatinib
- dextromethorphan-quinidine
- Diflucan
- Diskets
- disopyramide
- dofetilide
- Dolophine
- dronedarone
- droperidol
- escitalopram oxalate
- ezetimibe-simvastatin
- Fabrazyme
- fingolimod
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- fosamprenavir
- Geodon
- Gilenya
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- ibutilide fumarate
- indinavir
- Invega
- Invega Sustenna
- Invirase
- isradipine
- itraconazole
- Ketek
- ketoconazole
- Lexapro
- Lexiva
- methadone
- Methadone Intensol
- Methadose
- miconazole
- Multaq
- Nebupent
- nelfinavir
- nilotinib
- Norpace
- Norpace Cr
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Nuedexta
- Onmel
- Orap
- Oravig
- paliperidone
- paliperidone palmitate
- pasireotide
- Pentam
- pentamidine
- pimozide
- posaconazole
- propafenone
- quinidine gluconate
- quinidine sulfate
- ritonavir
- Rythmol
- saquinavir mesylate
- Signifor
- Sirturo
- Sorine
- sotalol
- Sotalol Af
- Sporanox
- Sporanox Pulsepak
- Sprycel
- Tasigna
- telithromycin
- Tikosyn
- tipranavir
- Trisenox
- vandetanib
- Vfend
- Vfend Iv
- Viracept
- voriconazole
- Vytorin 10-40
- Vytorin 10-80
- ziprasidone HCl
- ziprasidone mesylate
Contraindicated
- Abstral
- Actiq
- Advair Diskus
- Advair Hfa
- alfuzosin
- Aloxi
- amantadine HCl
- Anzemet
- arformoterol
- Astagraf Xl
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Belladonna-phenobarbital
- Brovana
- budesonide-formoterol
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- Butrans
- calcium-mag-B complex-D3-hrb61
- carbamazepine
- Carbatrol
- Cardene Iv
- Cardene Iv In Dextrose
- Cardene Iv In Sodium Chloride
- Cardene Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Cerebyx
- clozapine
- Clozaril
- Cold & Flu Fighter
- Complera
- Coumadin
- crizotinib
- Digox
- digoxin
- Dilacor Xr
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Dilt-xr
- diltiazem HCl
- dolasetron
- Donnatal
- Dulera
- Duragesic
- Edurant
- Effexor Xr
- emtricitab-rilpivirine-tenofov
- Eovist
- Epitol
- Equetro
- eribulin
- ezogabine
- Fareston
- Fatigue Relief Complex
- Fazaclo
- felbamate
- Felbatol
- fentanyl
- fentanyl citrate
- fentanyl citrate (PF)
- Fentora
- flecainide
- fluticasone-salmeterol
- Foradil Aerolizer
- formoterol fumarate
- foscarnet
- Foscavir
- fosphenytoin
- gadoxetate
- granisetron
- granisetron (PF)
- Granisol
- Halaven
- Hecoria
- Hycamtin
- indapamide
- isoniazid-rifamp-pyrazinamide
- Istodax
- Jantoven
- Lanoxin
- Lanoxin Pediatric
- lapatinib
- Lazanda
- Levitra
- lithium carbonate
- lithium citrate
- Lithobid
- Luminal
- Matzim La
- moexipril
- moexipril-hydrochlorothiazide
- mometasone-formoterol
- Mysoline
- Nexavar
- nicardipine
- nicardipine in dextrose,iso-os
- nicardipine in NaCl (iso-os)
- octreotide acetate
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- palonosetron
- pazopanib
- Perforomist
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Potiga
- primidone
- Prograf
- Qualaquin
- quetiapine
- quinine sulfate
- quinupristin-dalfopristin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- rilpivirine
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- romidepsin
- salmeterol
- Sancuso
- Sandostatin
- Sandostatin Lar Depot
- Serevent Diskus
- Seroquel
- Seroquel Xr
- Soltamox
- sorafenib
- St. John's wort
- Sublimaze (pf)
- Suboxone
- Subsys
- Symbicort
- Synercid
- tacrolimus
- tamoxifen
- Taztia Xt
- Tegretol
- Tegretol Xr
- telavancin
- tetrabenazine
- thioridazine
- Tiazac
- tizanidine
- topotecan
- toremifene
- Tykerb
- Uniretic
- Univasc
- Uroxatral
- vardenafil
- vemurafenib
- venlafaxine
- Versacloz
- Vibativ
- vit C-St. John wort-elder-hb30
- Votrient
- warfarin
- Women's Complex
- Xalkori
- Xenazine
- Zanaflex
- Zelboraf
- Zofran
- Zofran Odt
- Zubsolv
- Zuplenz
Severe
Moderate
- Advicor
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- afatinib
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- Altoprev
- amlodipine-atorvastatin
- Anaprox
- Anaprox Ds
- Ansaid
- Anti-diarrhea
- Anti-diarrheal (lope)-anti-gas
- Anti-diarrheal (loperamide)
- Arthrotec 50
- atazanavir
- atorvastatin
- Bystolic
- Caduet
- Caldolor
- Cambia
- Cataflam
- Celebrex
- celecoxib
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- cyclosporine
- cyclosporine modified
- darunavir
- Detrol
- Detrol La
- Diamode
- diclofenac epolamine
- diclofenac potassium
- diclofenac sodium
- diclofenac submicronized
- diclofenac-misoprostol
- Duexis
- Dutoprol
- Ec-naprosyn
- ethotoin
- ezetimibe-atorvastatin
- Feldene
- Flanax
- Flector
- flurbiprofen
- Gengraf
- Gilotrif
- hydrocodone-ibuprofen
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Imodium Multi-symptom Relief
- Inderal La
- Inderal Xl
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- Innopran Xl
- Juxtapid
- Kaletra
- Lipitor
- Liptruzet
- Lo-peramide
- lomitapide
- loperamide
- loperamide-simethicone
- lopinavir-ritonavir
- Lopressor
- Lopressor Hct
- lovastatin
- Medi-profen
- Mediproxen
- meloxicam
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Mevacor
- Midol (naproxen)
- Mobic
- Motrin Ib
- Motrin Pm
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- nebivolol
- Neoprofen (ibuprofen Lysn)(pf)
- Neoral
- niacin-lovastatin
- niacin-simvastatin
- Peganone
- piroxicam
- Prezista
- procainamide
- propranolol
- propranolol-hydrochlorothiazid
- Provil
- pseudoephedrine-ibuprofen
- Rapamune
- Reprexain
- Reyataz
- rivaroxaban
- Sandimmune
- Simcor
- simvastatin
- Sinus & Cold-d
- sirolimus
- sunitinib
- Sutent
- tolterodine
- Toprol Xl
- Ultra A-d
- Vicoprofen
- Vimovo
- Voltaren-xr
- Vytorin 10-10
- Vytorin 10-20
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Xarelto
- Zipsor
- Zocor
- Zorvolex
- Bradycardia
- Cardiogenic shock
- Complete atrioventricular block
- Lactating mother
- Refractive keratoplasty by laser surgery
- Second degree atrioventricular heart block
- Sinus node dysfunction
- Syncope due to bradycardia
Contraindicated
- Alveolar hemorrhage
- Chronic pulmonary disease
- Congenital long QT syndrome
- Drug-induced hepatitis
- Eosinophilic pneumonia
- Hypersensitivity pneumonitis
- Hyperthyroidism
- Hypokalemia
- Hypomagnesemia
- Hypothyroidism
- Interstitial pneumonitis
- Optic neuritis
- Optic neuropathy
- Pregnancy
- Prolonged QT interval
- Thyrotoxicosis
- Torsades de pointes
Severe
Moderate
- Abnormal hepatic function tests
- Corneal deposits
- Disease of liver
- Invasive surgical procedure
- Peripheral neuropathy
AMIODARONE HCL (AMIODARONE HCL)
- Life-threatening ventricular tachycardia
- Ventricular fibrillation
- Prevention of ventricular fibrillation
- Abnormal hepatic function tests
- Alveolitis
- Hypotension
- Interstitial pneumonitis
- Pulmonary fibrosis
- Skin photosensitivity
- Anorexia
- Ataxia
- Constipation
- Fatigue
- Malaise
- Nausea
- Tremor
- Vomiting
More Frequent
Severe
Less Severe
- Blurred vision
- Cardiac arrhythmia
- Chronic heart failure
- Corneal deposits
- Dyschromia
- Hyperthyroidism
- Hypothyroidism
- Optic neuritis
- Optic neuropathy
- Prolonged QT interval
- Sinus bradycardia
- Torsades de pointes
- Visual halos
- Abnormal sexual function
- Acute abdominal pain
- Dizziness
- Dry eye
- Dysgeusia
- Ecchymosis
- Flushing
- Headache disorder
- Insomnia
- Libido changes
- Paresthesia
- Photophobia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute pancreatitis
- Acute respiratory distress syndrome
- Acute respiratory insufficiency
- Agranulocytosis
- Allergic dermatitis
- Anaphylaxis
- Angioedema
- Aplastic anemia
- Atrial fibrillation
- Atrioventricular block
- Bradycardia
- Bronchiolitis obliterans
- Bronchospastic pulmonary disease
- Bullous dermatitis
- Cholestasis
- Cholestatic hepatitis
- Corneal degeneration
- Demyelination
- DRESS syndrome
- Dyspnea
- Edema
- Eosinophilic pneumonia
- Epididymitis
- Erythema multiforme
- Exfoliative dermatitis
- Hallucinations
- Heart block
- Hemolytic anemia
- Hemoptysis
- Hepatitis
- Hypersensitivity pneumonitis
- Hypoxia
- Idiopathic intracranial hypertension
- Injection site sequelae
- Kidney disease with reduction in GFR
- Lupus-like syndrome
- Lymphadenopathy
- Malignant neoplasm of skin
- Myopathy
- Neutropenic disorder
- Pancytopenia
- Papilledema
- Parkinsonism
- Paroxysmal ventricular tachycardia
- Peripheral demyelinating neuropathy
- Peripheral neuropathy
- Pleural effusions
- Pleuritis
- Pulmonary edema
- Pulmonary hemorrhage
- Renal failure
- Rhabdomyolysis
- Scotomata
- Shock
- SIADH syndrome
- Sinus arrest
- Sinus node dysfunction
- Skin rash
- Stevens-johnson syndrome
- Thrombocytopenic disorder
- Thyroid carcinoma
- Tissue necrosis
- Toxic epidermal necrolysis
- Vasculitis
Less Severe
- Acute confusion
- Alopecia
- Back pain
- Bradykinesia
- Cough
- Delirium
- Eczema
- Eosinophilia
- Erectile dysfunction
- Facial edema
- Fever
- Gait abnormality
- Involuntary muscle movement
- Muscle spasm
- Muscle weakness
- Sialorrhea
- Sleep disorder
- Urticaria
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Amiodarone (Oral)
Risk of AV block, bradycardia, hypotension. Safety and efficacy not established per manufacturer.
- 1 Day – 18 Years
- Risk of AV block, bradycardia, hypotension. Safety and efficacy not established per manufacturer.
Amiodarone
- Severity Level:
D
- Additional Notes: Incr risk of fetal adverse effects
Contraindicated
Amiodarone
Possible hypothyroidism & cv effects;Consider long t1/2 of drug(15-142 days)
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Excreted | Not known; no or inclusive data | Possible hypothyroidism & cv effects;Consider long t1/2 of drug(15-142 days) |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Amiodarone
Cardiovascular-Risk for Torsades de pointes. Follow QTc intervals. Endocrine-Monitor for hyperthyroidism. Pulmonary-Toxicity has been reported days to weeks after drug initiation. Preexisting pulmonary disease incurs a poorer prognosis if toxicity develops. Monitor for cough and progressive dyspnea. Hepatic-Elevated hepatic transaminases are common. Neuro/Psych-Monitor for peripheral neuropathy, coordination and gait deficits. Optic neuropathy and neuritis has been reported.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | Y | Y | Y |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- Though this medication often gives great benefits to people with irregular heartbeat, it may rarely worsen an irregular heartbeat or cause serious (sometimes fatal) side effects. When starting treatment with this drug, your doctor may have you stay in the hospital for proper monitoring. Amiodarone may take 2 weeks or longer to have an effect in your body.<br /><br />Also, this drug stays in your body for weeks to months, even after you are no longer taking it. Therefore, serious side effects may occur weeks to months after taking amiodarone. Serious side effects may include lung or liver problems. Tell your doctor right away if you notice any symptoms of lung or liver problems such as cough, shortness of breath, chest pain, coughing up blood, persistent nausea/vomiting, dark urine, severe stomach/abdominal pain, or yellowing eyes/skin.
| Life-threatening ventricular tachycardia | |
| I47.2 | Ventricular tachycardia |
| Prevention of ventricular fibrillation | |
| I49.01 | Ventricular fibrillation |
| Ventricular fibrillation | |
| I49.01 | Ventricular fibrillation |
| 0-9 | A-Z |
|---|---|
| I47.2 | Ventricular tachycardia |
| I49.01 | Ventricular fibrillation |
| I49.01 | Ventricular fibrillation |
Formulary Reference Tool