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NIACIN (niacin)
- Niacin deficiency
- High density lipoprotein deficiency
- Hypercholesterolemia
- Hyperlipidemia
- Niacin deficiency
- Hypertriglyceridemia
- Mixed hyperlipidemia
- Myocardial reinfarction prevention
- Pellagra
- Treatment to slow progression of coronary artery disease
- Niacinamide Tablet
- Niacin Tablet
- Niacin Tab
- Niacin Er Capsule,extended Release
- Niacin (niacinamide) Tablet
- By Indication
500 mg tablet
- Dosage information is not available
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day with meals
250 mg tablet
- Dosage information is not available
50 mg tablet
- 1 tablet (50 mg) by oral route once daily
500 mg tablet
- 1 tablet (500 mg) by oral route 3 times per day
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day with meals
250 mg tablet
- Dosage information is not available
50 mg tablet
- 1 tablet (50 mg) by oral route once daily
500 mg tablet
- 1 tablet (500 mg) by oral route 3 times per day
ER 250 mg capsule,extended release
- 1 capsule (250 mg) by oral route once daily
ER 500 mg capsule,extended release
- 1 capsule (500 mg) by oral route once daily
(amide) 500 mg tablet
- Dosage information is not available
High density lipoprotein deficiency
- 2 tablets (1,000 mg) by oral route 3 times per day
- 2 tablets (1,000 mg) by oral route 2 times per day
- 1 tablet (1,000 mg) by oral route once daily at bedtime
- 2 tablets (2,000 mg) by oral route once daily at bedtime
- 1 tablet (500 mg) by oral route 3 times per day
Hypercholesterolemia
- 2 tablets (1,000 mg) by oral route 3 times per day
- 2 tablets (1,000 mg) by oral route 2 times per day
- 1 tablet (500 mg) by oral route 3 times per day
Hyperlipidemia
- 2 tablets (1,000 mg) by oral route 3 times per day
- 2 tablets (1,000 mg) by oral route 2 times per day
- 1 tablet (1,000 mg) by oral route 3 times per day
- 10 tablets (1,000 mg) by oral route 3 times per day
- 2 tablets (2,000 mg) by oral route 3 times per day
- 1 capsule (250 mg) by oral route once daily
- 1 tablet (500 mg) by oral route once daily
- 1 tablet (500 mg) by oral route 3 times per day
- 1 capsule (500 mg) by oral route once daily
- 2 capsules (500 mg) by oral route once daily
- 1 tablet (750 mg) by oral route once daily
Hypertriglyceridemia
- 2 tablets (1,000 mg) by oral route 3 times per day
- 2 tablets (1,000 mg) by oral route 2 times per day
- 1 tablet (500 mg) by oral route 3 times per day
Mixed hyperlipidemia
- 2 tablets (1,000 mg) by oral route 3 times per day
- 2 tablets (1,000 mg) by oral route 2 times per day
- 1 tablet (500 mg) by oral route 3 times per day
Niacin deficiency
- 1 tablet (100 mg) by oral route 2 times per day with meals
- 1 tablet (100 mg) by oral route 3 times per day with meals
- None
Contraindicated
- Advicor
- Altoprev
- amlodipine-atorvastatin
- atorvastatin
- Caduet
- Crestor
- ezetimibe-atorvastatin
- ezetimibe-simvastatin
- Lipitor
- Liptruzet
- Livalo
- lovastatin
- Mevacor
- niacin-lovastatin
- niacin-simvastatin
- pitavastatin
- Pravachol
- pravastatin
- rosuvastatin
- Simcor
- simvastatin
- Vytorin 10-10
- Vytorin 10-20
- Vytorin 10-40
- Vytorin 10-80
- Zocor
Severe
Moderate
- None
- Acute cerebral infarction
- Acute myocardial infarction
- Arterial hemorrhage
- Cerebrovascular accident
- Disease of liver
- Peptic ulcer
Contraindicated
- Abnormal hepatic function tests
- Alcoholism
- Disease of liver
- Increased risk of bleeding due to coagulation disorder
- Rhabdomyolysis
- Unstable angina pectoris
Severe
Moderate
- 30 day risk period post-myocardial infarction
- Cerebrovascular insufficiency
- Diabetes mellitus
- Gout
- Hypophosphatemia
- Hypotension
- Increased risk of bleeding due to coagulation disorder
NIACIN (niacin)
- Niacin deficiency
- High density lipoprotein deficiency
- Hypercholesterolemia
- Hyperlipidemia
- Niacin deficiency
- Hypertriglyceridemia
- Mixed hyperlipidemia
- Myocardial reinfarction prevention
- Pellagra
- Treatment to slow progression of coronary artery disease
- None
- Cough
- Diarrhea
- Dyspepsia
- Flatulence
- Flushing
- Heartburn
- Nausea
- Pruritus of skin
- Stinging of skin
- Vomiting
More Frequent
Severe
Less Severe
- None
- Abdominal pain with cramps
- Cardiac arrhythmia
- Diarrhea
- Dizziness
- Dry eye
- Dry skin
- Exacerbation of peptic ulcer
- Flushing
- Headache disorder
- Hyperglycemia
- Hyperuricemia
- Hypophosphatemia
- Hypotension
- Myalgias
- Nausea
- Pruritus of skin
- Skin rash
- Syncope
- Tachycardia
- Thrombocytopenic disorder
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Anaphylaxis
- Angioedema
- Drug-induced hepatitis
- Dyspnea
- Edema
- Jaundice
- Laryngismus
- Macular retinal edema
- Myopathy
- Paresthesia
- Urticaria
Less Severe
- Abdominal distension
- Blurred vision
- Cardiac arrhythmia
- Chills
- Dyschromia
- Eructation
- Flatulence
- General weakness
- Headache disorder
- Hyperhidrosis
- Hypoprothrombinemia
- Hypotension
- Insomnia
- Migraine
- Muscle weakness
- Nervousness
- Orthostatic hypotension
- Palpitations
- Skin pigmentation enhancement
- Skin rash
- Syncope
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Niacin Extended Release
No established safety and efficacy age < 16 years.
- 1 Day – 16 Years
- No established safety and efficacy age < 16 years.
Niacin (> 50 Mg)
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Niacin
Potential adverse effect on infant with lipid altering dose
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Potential adverse effect on infant with lipid altering dose |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| High density lipoprotein deficiency | |
| E78.6 | Lipoprotein deficiency |
| Hypercholesterolemia | |
| E78.0 | Pure hypercholesterolemia |
| E78.00 | Pure hypercholesterolemia, unspecified |
| E78.01 | Familial hypercholesterolemia |
| Hyperlipidemia | |
| E78.2 | Mixed hyperlipidemia |
| E78.4 | Other hyperlipidemia |
| E78.49 | Other hyperlipidemia |
| E78.5 | Hyperlipidemia, unspecified |
| Hypertriglyceridemia | |
| E78.1 | Pure hyperglyceridemia |
| E78.2 | Mixed hyperlipidemia |
| Mixed hyperlipidemia | |
| E78.2 | Mixed hyperlipidemia |
| Myocardial reinfarction prevention | |
| I21 | Acute myocardial infarction |
| I21.0 | ST elevation (STEMi) myocardial infarction of anterior wall |
| I21.01 | ST elevation (STEMi) myocardial infarction involving left main coronary artery |
| I21.02 | ST elevation (STEMi) myocardial infarction involving left anterior descending coronary artery |
| I21.09 | ST elevation (STEMi) myocardial infarction involving other coronary artery of anterior wall |
| I21.1 | ST elevation (STEMi) myocardial infarction of inferior wall |
| I21.11 | ST elevation (STEMi) myocardial infarction involving right coronary artery |
| I21.19 | ST elevation (STEMi) myocardial infarction involving other coronary artery of inferior wall |
| I21.2 | ST elevation (STEMi) myocardial infarction of other sites |
| I21.21 | ST elevation (STEMi) myocardial infarction involving left circumflex coronary artery |
| I21.29 | ST elevation (STEMi) myocardial infarction involving other sites |
| I21.3 | ST elevation (STEMi) myocardial infarction of unspecified site |
| I21.4 | Non-ST elevation (NSTEMi) myocardial infarction |
| I21.9 | Acute myocardial infarction, unspecified |
| I21.A | Other type of myocardial infarction |
| I21.A1 | Myocardial infarction type 2 |
| I21.A9 | Other myocardial infarction type |
| I22 | Subsequent ST elevation (STEMi) and non-ST elevation (NSTEMi) myocardial infarction |
| I22.0 | Subsequent ST elevation (STEMi) myocardial infarction of anterior wall |
| I22.1 | Subsequent ST elevation (STEMi) myocardial infarction of inferior wall |
| I22.2 | Subsequent non-ST elevation (NSTEMi) myocardial infarction |
| I22.8 | Subsequent ST elevation (STEMi) myocardial infarction of other sites |
| I22.9 | Subsequent ST elevation (STEMi) myocardial infarction of unspecified site |
| I25.2 | Old myocardial infarction |
| Niacin deficiency | |
| E52 | Niacin deficiency [pellagra] |
| Pellagra | |
| E52 | Niacin deficiency [pellagra] |
| Treatment to slow progression of coronary artery disease | |
| I25 | Chronic ischemic heart disease |
| I25.1 | Atherosclerotic heart disease of native coronary artery |
| I25.10 | Atherosclerotic heart disease of native coronary artery without angina pectoris |
| I25.11 | Atherosclerotic heart disease of native coronary artery with angina pectoris |
| I25.110 | Atherosclerotic heart disease of native coronary artery with unstable angina pectoris |
| I25.111 | Atherosclerotic heart disease of native coronary artery with angina pectoris with documented spasm |
| I25.118 | Atherosclerotic heart disease of native coronary artery with other forms of angina pectoris |
| I25.119 | Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris |
| I25.7 | Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris |
| I25.70 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris |
| I25.700 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris |
| I25.701 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris with documented spasm |
| I25.708 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with other forms of angina pectoris |
| I25.709 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unspecified angina pectoris |
| I25.71 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris |
| I25.710 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unstable angina pectoris |
| I25.711 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.718 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.719 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.72 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris |
| I25.720 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unstable angina pectoris |
| I25.721 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.728 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.729 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.73 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris |
| I25.730 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unstable angina pectoris |
| I25.731 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.738 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.739 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.75 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris |
| I25.750 | Atherosclerosis of native coronary artery of transplanted heart with unstable angina |
| I25.751 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.758 | Atherosclerosis of native coronary artery of transplanted heart with other forms of angina pectoris |
| I25.759 | Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris |
| I25.76 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris |
| I25.760 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unstable angina |
| I25.761 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.768 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with other forms of angina pectoris |
| I25.769 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unspecified angina pectoris |
| I25.79 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris |
| I25.790 | Atherosclerosis of other coronary artery bypass graft(s) with unstable angina pectoris |
| I25.791 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.798 | Atherosclerosis of other coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.799 | Atherosclerosis of other coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.8 | Other forms of chronic ischemic heart disease |
| I25.81 | Atherosclerosis of other coronary vessels without angina pectoris |
| I25.810 | Atherosclerosis of coronary artery bypass graft(s) without angina pectoris |
| I25.811 | Atherosclerosis of native coronary artery of transplanted heart without angina pectoris |
| I25.812 | Atherosclerosis of bypass graft of coronary artery of transplanted heart without angina pectoris |
| I25.82 | Chronic total occlusion of coronary artery |
| I25.83 | Coronary atherosclerosis due to lipid rich plaque |
| I25.84 | Coronary atherosclerosis due to calcified coronary lesion |
| I25.89 | Other forms of chronic ischemic heart disease |
| I25.9 | Chronic ischemic heart disease, unspecified |
| 0-9 | A-Z |
|---|---|
| E52 | Niacin deficiency [pellagra] |
| E52 | Niacin deficiency [pellagra] |
| E78.0 | Pure hypercholesterolemia |
| E78.00 | Pure hypercholesterolemia, unspecified |
| E78.01 | Familial hypercholesterolemia |
| E78.1 | Pure hyperglyceridemia |
| E78.2 | Mixed hyperlipidemia |
| E78.2 | Mixed hyperlipidemia |
| E78.2 | Mixed hyperlipidemia |
| E78.4 | Other hyperlipidemia |
| E78.49 | Other hyperlipidemia |
| E78.5 | Hyperlipidemia, unspecified |
| E78.6 | Lipoprotein deficiency |
| I21 | Acute myocardial infarction |
| I21.0 | ST elevation (STEMi) myocardial infarction of anterior wall |
| I21.01 | ST elevation (STEMi) myocardial infarction involving left main coronary artery |
| I21.02 | ST elevation (STEMi) myocardial infarction involving left anterior descending coronary artery |
| I21.09 | ST elevation (STEMi) myocardial infarction involving other coronary artery of anterior wall |
| I21.1 | ST elevation (STEMi) myocardial infarction of inferior wall |
| I21.11 | ST elevation (STEMi) myocardial infarction involving right coronary artery |
| I21.19 | ST elevation (STEMi) myocardial infarction involving other coronary artery of inferior wall |
| I21.2 | ST elevation (STEMi) myocardial infarction of other sites |
| I21.21 | ST elevation (STEMi) myocardial infarction involving left circumflex coronary artery |
| I21.29 | ST elevation (STEMi) myocardial infarction involving other sites |
| I21.3 | ST elevation (STEMi) myocardial infarction of unspecified site |
| I21.4 | Non-ST elevation (NSTEMi) myocardial infarction |
| I21.9 | Acute myocardial infarction, unspecified |
| I21.A | Other type of myocardial infarction |
| I21.A1 | Myocardial infarction type 2 |
| I21.A9 | Other myocardial infarction type |
| I22 | Subsequent ST elevation (STEMi) and non-ST elevation (NSTEMi) myocardial infarction |
| I22.0 | Subsequent ST elevation (STEMi) myocardial infarction of anterior wall |
| I22.1 | Subsequent ST elevation (STEMi) myocardial infarction of inferior wall |
| I22.2 | Subsequent non-ST elevation (NSTEMi) myocardial infarction |
| I22.8 | Subsequent ST elevation (STEMi) myocardial infarction of other sites |
| I22.9 | Subsequent ST elevation (STEMi) myocardial infarction of unspecified site |
| I25 | Chronic ischemic heart disease |
| I25.1 | Atherosclerotic heart disease of native coronary artery |
| I25.10 | Atherosclerotic heart disease of native coronary artery without angina pectoris |
| I25.11 | Atherosclerotic heart disease of native coronary artery with angina pectoris |
| I25.110 | Atherosclerotic heart disease of native coronary artery with unstable angina pectoris |
| I25.111 | Atherosclerotic heart disease of native coronary artery with angina pectoris with documented spasm |
| I25.118 | Atherosclerotic heart disease of native coronary artery with other forms of angina pectoris |
| I25.119 | Atherosclerotic heart disease of native coronary artery with unspecified angina pectoris |
| I25.2 | Old myocardial infarction |
| I25.7 | Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris |
| I25.70 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris |
| I25.700 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unstable angina pectoris |
| I25.701 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with angina pectoris with documented spasm |
| I25.708 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with other forms of angina pectoris |
| I25.709 | Atherosclerosis of coronary artery bypass graft(s), unspecified, with unspecified angina pectoris |
| I25.71 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris |
| I25.710 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unstable angina pectoris |
| I25.711 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.718 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.719 | Atherosclerosis of autologous vein coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.72 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris |
| I25.720 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unstable angina pectoris |
| I25.721 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.728 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.729 | Atherosclerosis of autologous artery coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.73 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris |
| I25.730 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unstable angina pectoris |
| I25.731 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.738 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.739 | Atherosclerosis of nonautologous biological coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.75 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris |
| I25.750 | Atherosclerosis of native coronary artery of transplanted heart with unstable angina |
| I25.751 | Atherosclerosis of native coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.758 | Atherosclerosis of native coronary artery of transplanted heart with other forms of angina pectoris |
| I25.759 | Atherosclerosis of native coronary artery of transplanted heart with unspecified angina pectoris |
| I25.76 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris |
| I25.760 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unstable angina |
| I25.761 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with angina pectoris with documented spasm |
| I25.768 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with other forms of angina pectoris |
| I25.769 | Atherosclerosis of bypass graft of coronary artery of transplanted heart with unspecified angina pectoris |
| I25.79 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris |
| I25.790 | Atherosclerosis of other coronary artery bypass graft(s) with unstable angina pectoris |
| I25.791 | Atherosclerosis of other coronary artery bypass graft(s) with angina pectoris with documented spasm |
| I25.798 | Atherosclerosis of other coronary artery bypass graft(s) with other forms of angina pectoris |
| I25.799 | Atherosclerosis of other coronary artery bypass graft(s) with unspecified angina pectoris |
| I25.8 | Other forms of chronic ischemic heart disease |
| I25.81 | Atherosclerosis of other coronary vessels without angina pectoris |
| I25.810 | Atherosclerosis of coronary artery bypass graft(s) without angina pectoris |
| I25.811 | Atherosclerosis of native coronary artery of transplanted heart without angina pectoris |
| I25.812 | Atherosclerosis of bypass graft of coronary artery of transplanted heart without angina pectoris |
| I25.82 | Chronic total occlusion of coronary artery |
| I25.83 | Coronary atherosclerosis due to lipid rich plaque |
| I25.84 | Coronary atherosclerosis due to calcified coronary lesion |
| I25.89 | Other forms of chronic ischemic heart disease |
| I25.9 | Chronic ischemic heart disease, unspecified |
Formulary Reference Tool