LEVOTHYROXINE SODIUM (levothyroxine sodium)
- Myxedema coma
levothyroxine 100 mcg intravenous powder for solution
- Inject 50 mcg by intravenous route once daily
levothyroxine 200 mcg intravenous powder for solution
- Inject 50 mcg by intravenous route once daily
levothyroxine 500 mcg intravenous powder for solution
- Inject 50 mcg by intravenous route once daily
levothyroxine 100 mcg intravenous powder for solution
- Inject 50 mcg by intravenous route once daily
levothyroxine 200 mcg intravenous powder for solution
- Inject 50 mcg by intravenous route once daily
levothyroxine 500 mcg intravenous powder for solution
- Inject 50 mcg by intravenous route once daily
Myxedema coma
- Inject 50 mcg by intravenous route once daily
- Inject 100 mcg by intravenous route once daily
- Inject 100 mcg by intravenous route once
- Inject 300 mcg by intravenous route once
- Inject 500 mcg by intravenous route once
- None
Contraindicated
- Coumadin
- Jantoven
- warfarin
Severe
Moderate
- Digox
- digoxin
- Lanoxin
- Lanoxin Pediatric
- Thyrotoxicosis crisis
Contraindicated
- Hyperthyroidism
- Pituitary insufficiency
- Primary adrenocortical insufficiency
Severe
Moderate
- Diabetes mellitus
- Osteopenia
- Osteoporosis
LEVOTHYROXINE SODIUM (levothyroxine sodium)
- Myxedema coma
- None
- Female infertility
More Frequent
Severe
Less Severe
- Osteopenia
- Hypertension
- Weight loss
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Allergic dermatitis
- Angina
- Angioedema
- Cardiac arrest
- Cardiac arrhythmia
- Dyspnea
- Heart failure
- Idiopathic intracranial hypertension
- Mood changes
- Seizure disorder
- Skin rash
- Tachycardia
- Urticaria
Less Severe
- Abdominal pain with cramps
- Alopecia
- Diarrhea
- Fatigue
- Fever
- Flushing
- Headache disorder
- Heat intolerance
- Hyperhidrosis
- Increased appetite
- Insomnia
- Irregular menstrual periods
- Irritability
- Menstrual disorder
- Muscle spasm
- Muscle weakness
- Nervousness
- Palpitations
- Pulse changes
- Symptoms of anxiety
- Tremor
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Levothyroxine
Monitor closely to avoid adverse effects on intellectual development, brain maturation, and linear growth due to overtreatment or undertreatment. Rare reports of pseudotumor cerebri and slipped capital femoral epiphysis.
- 1 Day – 18 Years
- Monitor closely to avoid adverse effects on intellectual development, brain maturation, and linear growth due to overtreatment or undertreatment. Rare reports of pseudotumor cerebri and slipped capital femoral epiphysis.
Levothyroxine Sodium
- Severity Level:
2
- Additional Notes: Human data suggest no known dev tox; monitor tsh for possible dose increases
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
None
General | Excretion Potential | Effect on Infant | Notes |
None |
No Known Risk
Levothyroxine Sodium
Limited data suggest no adverse effects on infant
General | Excretion Potential | Effect on Infant | Notes |
No known risks; does not adversely affect lactation | Excreted | No adverse effect | Limited data suggest no adverse effects on infant |
Contraindicated
None
Precaution Exists
Levothyroxine
General-Elderly may be more sensitive to l-thyroxine. Start at lower dose. Cardiovascular-Use caution and start at lower doses in those patients with cardiac disease, particularly atrial fibrillation.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | N | N | Y | Y | N | Y |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- This medication should not be used for weight loss. Normal doses of this medication will not cause weight loss in people with normal thyroid function. Large doses of this medication may cause very serious (possibly fatal) side effects, especially when taken with diet pills.
Myxedema coma | |
E03.5 | Myxedema coma |
0-9 | A-Z |
---|---|
E03.5 | Myxedema coma |