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METHSCOPOLAMINE BROMIDE (methscopolamine bromide)
- Peptic ulcer
2.5 mg tablet
- 1 tablet (2.5 mg) by oral route 3 times per day before meals then 1 tablet (2.5 mg) by oral route at bedtime
5 mg tablet
- 1 tablet (5 mg) 30 minutes before meals and at bedtime by oral route 4 times per day
methscopolamine 2.5 mg tablet
- 1 tablet (2.5 mg) by oral route 3 times per day before meals then 1 tablet (2.5 mg) by oral route at bedtime
methscopolamine 5 mg tablet
- 1 tablet (5 mg) 30 minutes before meals and at bedtime by oral route 4 times per day
Peptic ulcer
- 1 tablet (5 mg) 30 minutes before meals and at bedtime by oral route 4 times per day
- 1 tablet (2.5 mg) by oral route 3 times per day before meals then 1 tablet (2.5 mg) by oral route at bedtime
- 1 tablet (2.5 mg) by oral route 3 times per day before meals then 2 tablets (5 mg) by oral route at bedtime
- pramlintide
- Symlinpen 120
- Symlinpen 60
Contraindicated
- K-tab
- Klor-con
- Klor-con 10
- Klor-con M10
- Klor-con M15
- Klor-con M20
- Medi-lyte
- potassium chloride
- potassium citrate
- potassium Cl-calcium phos-mag
- sodium Cl-potassium chloride
- Thermotabs
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
Severe
Moderate
- Adasuve
- chlorpromazine
- Compazine
- Compro
- fluphenazine decanoate
- fluphenazine HCl
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- loxapine
- loxapine succinate
- Loxitane
- perphenazine
- perphenazine-amitriptyline
- Phenadoz
- Phenergan
- prochlorperazine
- prochlorperazine Edisylate
- prochlorperazine maleate
- promethazine
- Promethazine Vc
- Promethazine Vc-codeine
- promethazine-codeine
- promethazine-DM
- promethazine-phenyleph-codeine
- promethazine-phenylephrine
- Promethegan
- thioridazine
- trifluoperazine
- Achalasia of esophagus
- Angle-closure glaucoma
- Atony of colon
- Hemorrhagic shock
- Myasthenia gravis
- Paralytic ileus
- Pyloroduodenal obstruction
- Severe ulcerative colitis
- Toxic megacolon
Contraindicated
- Autonomic dysreflexia
- Benign prostatic hyperplasia
- Gastric ulcer
- Gastrointestinal obstruction
- Hiatal hernia
- Reflux esophagitis
- Sinus tachycardia
- Toxin-mediated diarrhea
- Ulcerative colitis
- Urinary retention
- Urinary tract obstructive uropathy
Severe
Moderate
- Chronic heart failure
- Chronic pulmonary disease
- Coronary artery disease
- Disease of liver
- Down's syndrome
- Drowsy
- Hypertension
- Hyperthyroidism
- Kidney disease with reduction in GFR
- Salivary secretion disorder
METHSCOPOLAMINE BROMIDE (methscopolamine bromide)
- Peptic ulcer
- None
- Constipation
- Decreased sweating
- Xerostomia
More Frequent
Severe
Less Severe
- None
- Breast milk flow decreased
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute confusion
- Allergic dermatitis
- Ocular hypertension
- Skin rash
- Urticaria
Less Severe
- Blurred vision
- Drowsy
- Dysuria
- Fatigue
- Flatulence
- General weakness
- Headache disorder
- Memory impairment
- Mydriasis
- Nausea
- Vomiting
Contraindicated
Scopolamine Or Methscopolamine
More sensitive to adverse effects. Avoid use for cough and cold symptoms.
- 1 Day – 6 Years
- 1 More sensitive to adverse effects. Avoid use for cough and cold symptoms.
Severe Precaution
(Meth)scopolamine
Infants and children are more sensitive to anticholinergic and adverse effects.
- 6 Years – 18 Years
- Infants and children are more sensitive to anticholinergic and adverse effects.
Management or Monitoring Precaution
None
Scopolamine
- Severity Level:
2
- Additional Notes: Limited data suggest seizures in pre-eclamptic women exposed to scopolamine.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Scopolamine
Insufficient data available; long term use may decrease milk production
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Insufficient data available; long term use may decrease milk production |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Methscopolamine
Neuro/Psych-Anticholinergic effects may cause sedation, hallucinations, dizziness, worsen cognitive impairment and increase fall risk. Non-sedating agents preferred. Gastrointestinal-Avoid with gastrointestinal ileus. May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- None
| Peptic ulcer | |
| K27 | Peptic ulcer, site unspecified |
| K27.0 | Acute peptic ulcer, site unspecified, with hemorrhage |
| K27.1 | Acute peptic ulcer, site unspecified, with perforation |
| K27.2 | Acute peptic ulcer, site unspecified, with both hemorrhage and perforation |
| K27.3 | Acute peptic ulcer, site unspecified, without hemorrhage or perforation |
| K27.4 | Chronic or unspecified peptic ulcer, site unspecified, with hemorrhage |
| K27.5 | Chronic or unspecified peptic ulcer, site unspecified, with perforation |
| K27.6 | Chronic or unspecified peptic ulcer, site unspecified, with both hemorrhage and perforation |
| K27.7 | Chronic peptic ulcer, site unspecified, without hemorrhage or perforation |
| K27.9 | Peptic ulcer, site unspecified, unspecified as acute or chronic, without hemorrhage or perforation |
| P78.82 | Peptic ulcer of newborn |
| 0-9 | A-Z |
|---|---|
| K27 | Peptic ulcer, site unspecified |
| K27.0 | Acute peptic ulcer, site unspecified, with hemorrhage |
| K27.1 | Acute peptic ulcer, site unspecified, with perforation |
| K27.2 | Acute peptic ulcer, site unspecified, with both hemorrhage and perforation |
| K27.3 | Acute peptic ulcer, site unspecified, without hemorrhage or perforation |
| K27.4 | Chronic or unspecified peptic ulcer, site unspecified, with hemorrhage |
| K27.5 | Chronic or unspecified peptic ulcer, site unspecified, with perforation |
| K27.6 | Chronic or unspecified peptic ulcer, site unspecified, with both hemorrhage and perforation |
| K27.7 | Chronic peptic ulcer, site unspecified, without hemorrhage or perforation |
| K27.9 | Peptic ulcer, site unspecified, unspecified as acute or chronic, without hemorrhage or perforation |
| P78.82 | Peptic ulcer of newborn |
Formulary Reference Tool