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FLUTAMIDE (FLUTAMIDE)
- Prostatic carcinoma
125 mg capsule
- 2 capsules (250 mg) by oral route every 8 hours
Prostatic carcinoma
- 2 capsules (250 mg) by oral route every 8 hours
- 2 capsules (250 mg) by oral route 3 times per day at 8-hour intervals
- natalizumab
- Tysabri
Contraindicated
- None
Severe
Moderate
- None
- Glucose-6-phosphate dehydrogenase (g6Pd) deficiency
- Hemolytic anemia from PK and g6PD deficiencies
- Hepatic failure
- Hyperbilirubinemia
- Lactating mother
- Severe hepatic disease
Contraindicated
- Abnormal hepatic function tests
- Disease of liver
- Methemoglobinemia
- NADH methemoglobin reductase deficiency
- Pregnancy
Severe
Moderate
- None
FLUTAMIDE (FLUTAMIDE)
- Prostatic carcinoma
- None
- Diarrhea
- Drug-induced hot flash
- Erectile dysfunction
- Gynecomastia
- Libido changes
More Frequent
Severe
Less Severe
- Anemia
- Hypertension
- Leukopenia
- Thrombocytopenic disorder
- Anorexia
- Drowsy
- Edema
- Nausea
- Nervousness
- Symptoms of anxiety
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Hemolytic anemia
- Hepatic failure
- Hepatitis
- Jaundice
- Methemoglobinemia
Less Severe
- Skin photosensitivity
- Urine discoloration
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Flutamide
No pediatric safety information; not studied.
- 1 Day – 18 Years
- No pediatric safety information; not studied.
Flutamide
- Severity Level:
D
- Additional Notes: Not indicated for use in women
Contraindicated
Flutamide
Drug not indicated in women.
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Drug not indicated in women. |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Rarely, flutamide has caused severe (sometimes fatal) liver problems. Immediately tell your doctor if you develop symptoms of liver problems (such as loss of appetite, persistent nausea/vomiting, persistent stomach/abdominal pain, severe tiredness, dark urine, yellowing eyes/skin, aching muscles, joint pain). Liver problems can happen at any time while taking flutamide, but they occur most often during the first 3 months of treatment.<br /><br />Your doctor will tell you whether to stop or continue flutamide. Your doctor will monitor your liver function with blood tests while you take flutamide. Keep all medical and laboratory appointments. Avoid alcohol while taking flutamide.
| Prostatic carcinoma | |
| C61 | Malignant neoplasm of prostate |
| 0-9 | A-Z |
|---|---|
| C61 | Malignant neoplasm of prostate |
Formulary Reference Tool