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DUTASTERIDE-TAMSULOSIN (DUTASTERIDE/TAMSULOSIN HCL)
- Benign prostatic hyperplasia with lower urinary tract sx
- Jalyn Capsule, Extended Release
- Dutasteride-tamsulosin Er Capsule Ext.release 24Hr Multiphas
- By Indication
0.5 mg-0.4 mg capsule, extended release
- 1 capsule by oral route once daily ;30 minutes after the same meal each day
dutasteride 0.5 mg-tamsulosin ER 0.4 mg capsule ext.release 24hr mphas
- 1 capsule by oral route once daily ;30 minutes after the same meal each day
Benign prostatic hyperplasia with lower urinary tract sx
- 1 capsule by oral route once daily ;30 minutes after the same meal each day
- amoxicil-clarithromy-lansopraz
- atazanavir
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- boceprevir
- clarithromycin
- conivaptan in 5 % dextrose
- Crixivan
- elvitegr-cobicist-emtric-tenof
- fosamprenavir
- Incivek
- indinavir
- Invirase
- itraconazole
- Kaletra
- Ketek
- ketoconazole
- Lexiva
- lopinavir-ritonavir
- nefazodone
- nelfinavir
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Onmel
- posaconazole
- Prevpac
- Reyataz
- ritonavir
- saquinavir mesylate
- Sporanox
- Sporanox Pulsepak
- Stribild
- telaprevir
- telithromycin
- Vaprisol
- Vfend
- Vfend Iv
- Victrelis
- Viracept
- voriconazole
Contraindicated
- None
Severe
Moderate
- Adcirca
- avanafil
- Calan
- Calan Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Cialis
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- dronedarone
- Levitra
- Matzim La
- Multaq
- Revatio
- sildenafil
- Stendra
- tadalafil
- Tarka
- Taztia Xt
- Tiazac
- trandolapril-verapamil
- vardenafil
- verapamil
- Verelan
- Verelan Pm
- Viagra
- Lactating mother
- Pregnancy
Contraindicated
- CYp2d6 poor metabolizer
- Intraoperative floppy iris syndrome
- Orthostatic hypotension
- Priapism
- Reduced activity of cytochrome p450 CYp3a4
Severe
Moderate
- Cataract surgery
- Disease of liver
- High-grade prostate cancer
DUTASTERIDE-TAMSULOSIN (DUTASTERIDE/TAMSULOSIN HCL)
- Benign prostatic hyperplasia with lower urinary tract sx
- None
- Back pain
- Diarrhea
- Disorder of ejaculation
- Dizziness
- Erectile dysfunction
- General weakness
- Headache disorder
- Rhinitis
More Frequent
Severe
Less Severe
- Blurred vision
- High-grade prostate cancer
- Chest pain
- Cough
- Drowsy
- Infection
- Insomnia
- Libido changes
- Nausea
- Pharyngitis
- Sinusitis
- Tooth disorder
- Vertigo
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Angioedema
- Atrial fibrillation
- Cardiac arrhythmia
- Erythema multiforme
- Exfoliative dermatitis
- Gynecomastia
- Intraoperative floppy iris syndrome
- Localized edema
- Malignant tumor of male breast
- Priapism
- Skin rash
- Stevens-johnson syndrome
- Syncope
- Urticaria
Less Severe
- Constipation
- Decrease ejaculate volume
- Depression
- Dizziness
- Dyspnea
- Epistaxis
- Hypotension
- Mastalgia
- Orthostatic hypotension
- Palpitations
- Pruritus of skin
- Testicular pain
- Testicular swelling
- Urticaria
- Visual changes
- Vomiting
- Xerostomia
Contraindicated
Dutasteride
Contraindicated in children; safety and efficacy not established age <18 years.
- 1 Day – 18 Years
- 1 Contraindicated in children; safety and efficacy not established age <18 years.
Severe Precaution
None
Management or Monitoring Precaution
Tamsulosin
Efficacy not established in bladder dysfunction associated with neurologic disorders in pediatric exclusivity studies. Risk/benefit assessment suggested.
- 1 Day – 18 Years
- Efficacy not established in bladder dysfunction associated with neurologic disorders in pediatric exclusivity studies. Risk/benefit assessment suggested.
Dutasteride
- Severity Level:
X
- Additional Notes: Drug is absorbed through skin, pregnant women should not handle capsule
Tamsulosin
- Severity Level:
2
- Additional Notes: Treatment not indicated in women.insuff human data available
Contraindicated
Dutasteride
Contraindicated for use in women and children
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Contraindicated for use in women and children |
Precaution Exists
Tamsulosin
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Benign prostatic hyperplasia with lower urinary tract sx | |
| N40.1 | Benign prostatic hyperplasia with lower urinary tract symptoms |
| 0-9 | A-Z |
|---|---|
| N40.1 | Benign prostatic hyperplasia with lower urinary tract symptoms |
Formulary Reference Tool