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FANAPT (ILOPERIDONE)
- Schizophrenia
1mg(2)-2 mg(2)-4mg(2)-6 mg(2) tablets in a dose pack
- Dosage information is not available
1 mg tablet
- 1 tablet (1 mg) by oral route 2 times per day
10 mg tablet
- 1 tablet (10 mg) by oral route 2 times per day
12 mg tablet
- 1 tablet (12 mg) by oral route 2 times per day
2 mg tablet
- 3 tablets (6 mg) by oral route 2 times per day
4 mg tablet
- 2 tablets (8 mg) by oral route 2 times per day
6 mg tablet
- 1 tablet (6 mg) by oral route 2 times per day
8 mg tablet
- 1 tablet (8 mg) by oral route 2 times per day
Schizophrenia
- 1 tablet (1 mg) by oral route 2 times per day
- 1 tablet (1 mg) by oral route once daily
- 2 tablets (2 mg) by oral route 2 times per day
- 1 tablet (2 mg) by oral route 2 times per day
- 3 tablets (3 mg) by oral route 2 times per day
- 1 tablet (4 mg) by oral route 2 times per day
- 2 tablets (4 mg) by oral route 2 times per day
- 1 tablet (6 mg) by oral route 2 times per day
- 3 tablets (6 mg) by oral route 2 times per day
- 2 tablets (8 mg) by oral route 2 times per day
- 1 tablet (8 mg) by oral route 2 times per day
- 1 tablet (10 mg) by oral route 2 times per day
- 2 tablets (12 mg) by oral route 2 times per day
- 1 tablet (12 mg) by oral route 2 times per day
- amiodarone
- amiodarone in dextrose,iso-osm
- artemether-lumefantrine
- Coartem
- Cordarone
- disopyramide
- dronedarone
- droperidol
- metoclopramide HCl
- Metozolv Odt
- Multaq
- Nexterone
- Norpace
- Norpace Cr
- Pacerone
- Reglan
Contraindicated
- Apokyn
- apomorphine
- arsenic trioxide
- bedaquiline
- Betapace
- Betapace Af
- cabergoline
- Caprelsa
- Celexa
- chloroquine phosphate
- chlorpromazine
- citalopram
- Corvert
- dasatinib
- dextromethorphan-quinidine
- Diskets
- dofetilide
- Dolophine
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- escitalopram oxalate
- Fareston
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- ibutilide fumarate
- Invega
- Invega Sustenna
- isradipine
- Lexapro
- methadone
- Methadone Intensol
- Methadose
- Nebupent
- nilotinib
- norfloxacin
- Noroxin
- Nuedexta
- paliperidone
- paliperidone palmitate
- pasireotide
- Pentam
- pentamidine
- propafenone
- Qualaquin
- quinidine gluconate
- quinidine sulfate
- quinine sulfate
- Rythmol
- Signifor
- Sirturo
- Sorine
- sotalol
- Sotalol Af
- Sprycel
- Tasigna
- thioridazine
- Tikosyn
- toremifene
- Trisenox
- vandetanib
Severe
Moderate
- Ablavar
- Advair Diskus
- Advair Hfa
- alfuzosin
- Aloxi
- amantadine HCl
- Anzemet
- asenapine
- Astagraf Xl
- Avelox
- Avelox Abc Pack
- Avelox In Nacl (iso-osmotic)
- azithromycin
- budesonide-formoterol
- carbidopa-levodopa
- carbidopa-levodopa-entacapone
- Cardene Iv
- Cardene Iv In Dextrose
- Cardene Iv In Sodium Chloride
- Cardene Sr
- clozapine
- Clozaril
- Complera
- Comtan
- crizotinib
- dolasetron
- Dulera
- Edurant
- Effexor Xr
- emtricitab-rilpivirine-tenofov
- entacapone
- Eovist
- eribulin
- ezogabine
- Fazaclo
- felbamate
- Felbatol
- fingolimod
- flecainide
- fluticasone-salmeterol
- Foradil Aerolizer
- formoterol fumarate
- foscarnet
- Foscavir
- gadofosveset trisodium
- gadoxetate
- Geodon
- Gilenya
- granisetron
- granisetron (PF)
- Granisol
- Halaven
- Hecoria
- indapamide
- Istodax
- lapatinib
- Levaquin
- Levaquin In 5 % Dextrose
- Levitra
- levofloxacin
- levofloxacin in D5W
- lithium carbonate
- lithium citrate
- Lithobid
- Mirapex
- Mirapex Er
- moexipril
- moexipril-hydrochlorothiazide
- mometasone-formoterol
- moxifloxacin
- moxifloxacin in NaCl (iso-osm)
- Nexavar
- nicardipine
- nicardipine in dextrose,iso-os
- nicardipine in NaCl (iso-os)
- Noxafil
- octreotide acetate
- ofloxacin
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- palonosetron
- pazopanib
- Perforomist
- posaconazole
- Potiga
- pramipexole
- Prograf
- quetiapine
- Requip
- Requip Xl
- rilpivirine
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- romidepsin
- ropinirole
- salmeterol
- Sancuso
- Sandostatin
- Sandostatin Lar Depot
- Saphris
- Saphris (black Cherry)
- Serevent Diskus
- Seroquel
- Seroquel Xr
- Sinemet
- Sinemet Cr
- Soltamox
- sorafenib
- Stalevo 100
- Stalevo 125
- Stalevo 150
- Stalevo 200
- Stalevo 50
- Stalevo 75
- sunitinib
- Sutent
- Symbicort
- tacrolimus
- tamoxifen
- telavancin
- tetrabenazine
- tizanidine
- Tykerb
- Uniretic
- Univasc
- Uroxatral
- vardenafil
- vemurafenib
- venlafaxine
- Versacloz
- Vibativ
- Votrient
- Xalkori
- Xenazine
- Zanaflex
- Zelboraf
- ziprasidone HCl
- ziprasidone mesylate
- Zithromax
- Zithromax Tri-pak
- Zithromax Z-pak
- Zmax
- Zofran
- Zofran Odt
- Zuplenz
- Agranulocytosis
- Congenital long QT syndrome
- Lactating mother
- Neuroleptic malignant syndrome
- Torsades de pointes
Contraindicated
- Acute myocardial infarction
- Acutely decompensated chronic heart failure
- Bradycardia
- Cardiac arrhythmia
- CYp2d6 poor metabolizer
- Disease of liver
- Dysphagia
- Hypokalemia
- Hypomagnesemia
- Increased cardiovascular event risk
- Parkinsonism
- Pregnancy
- Priapism
- Senile dementia
- Severe hepatic disease
- Severe neutropenic disorder
- Suicidal
- Tardive dyskinesia
Severe
Moderate
- Acute confusion
- Carcinoma of breast
- Diabetes mellitus
- Hyperlipidemia
- Hyperprolactinemia
- Leukopenia
- Lower seizure threshold
- Neutropenic disorder
- Obesity
- Orthostatic hypotension
- Seizure disorder
- Weight gain
FANAPT (ILOPERIDONE)
- Schizophrenia
- Aggressive behavior
- Dizziness
- Extrapyramidal disease
- Libido changes
- Orthostatic hypotension
- Tachycardia
- Conjunctivitis
- Drowsy
- Fatigue
- Muscle spasm
- Myalgias
- Nasal congestion
- Nausea
- Urinary incontinence
- Weight gain
- Xerostomia
More Frequent
Severe
Less Severe
- Akathisia
- Amenorrhea
- Blurred vision
- Dyspnea
- Galactorrhea not associated with childbirth
- Hypotension
- Skin rash
- Tremor
- Acute abdominal pain
- Acute confusion
- Arthralgias
- Diarrhea
- Erectile dysfunction
- Hyperlipidemia
- Hyperprolactinemia
- Nervousness
- Palpitations
- Pharyngitis
- Upper respiratory infection
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Agranulocytosis
- Altered mental status
- Anaphylaxis
- Angioedema
- Biliary calculus
- Cerebral ischemia
- Cerebrovascular accident
- Chronic heart failure
- Delusional disorder
- Diabetes mellitus
- Edema
- Esophageal dysmotility
- Fever
- Hostility
- Hyperglycemia
- Leukopenia
- Manic disorder
- Memory impairment
- Menorrhagia
- Mood changes
- Neuroleptic malignant syndrome
- Neutropenic disorder
- Parkinsonism
- Priapism
- Prolonged QT interval
- Syncope
- Tardive dyskinesia
- Throat constriction
Less Severe
- Acquired dystonia
- Anemia
- Appetite changes
- Cataracts
- Conjunctival hyperemia
- Dry eye
- Edema of the oral soft tissue
- Epistaxis
- Eyelid edema
- Facial edema
- Gastritis
- Menstrual disorder
- Nystagmus
- Paresthesia
- Pruritus of skin
- Retrograde ejaculation
- Rhinitis
- Sialorrhea
- Stomatitis
- Tinnitus
- Urticaria
- Vertigo
- Weight loss
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Iloperidone
Safety and efficacy not established.
- 1 Day – 18 Years
- Safety and efficacy not established.
Iloperidone
- Severity Level:
D
- Additional Notes: Non-teratogenic complications (resp, gi,cns) with exposure during 3rd trimester
Contraindicated
Iloperidone
Mfr recommends avoiding breastfeeding
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Mfr recommends avoiding breastfeeding |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Iloperidone
Neuro/Psych-Increased risk of CVA, TIA and all cause mortality in senile dementia. Risk of impaired psychomotor function, tardive dyskinesia. Cardiovascular-May cause orthostatic hypotension, dizziness. Titrate dosage upward slowly. QT prolongation risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | Y | N | Y |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- There may be a slightly increased risk of serious, possibly fatal side effects (such as stroke, heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor. If you are using iloperidone in combination with other medication to treat depression, also carefully read the drug information for the other medication.
| Schizophrenia | |
| F20 | Schizophrenia |
| F20.0 | Paranoid schizophrenia |
| F20.1 | Disorganized schizophrenia |
| F20.2 | Catatonic schizophrenia |
| F20.3 | Undifferentiated schizophrenia |
| F20.5 | Residual schizophrenia |
| F20.8 | Other schizophrenia |
| F20.81 | Schizophreniform disorder |
| F20.89 | Other schizophrenia |
| F20.9 | Schizophrenia, unspecified |
| 0-9 | A-Z |
|---|---|
| F20 | Schizophrenia |
| F20.0 | Paranoid schizophrenia |
| F20.1 | Disorganized schizophrenia |
| F20.2 | Catatonic schizophrenia |
| F20.3 | Undifferentiated schizophrenia |
| F20.5 | Residual schizophrenia |
| F20.8 | Other schizophrenia |
| F20.81 | Schizophreniform disorder |
| F20.89 | Other schizophrenia |
| F20.9 | Schizophrenia, unspecified |
Formulary Reference Tool