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COSENTYX (secukinumab)
- moderate to severe plaque psoriasis
- psoriasis associated with arthritis
- rheumatic disease causing pain & stiffness in backbone
- juvenile enthesitis-related arthritis
- non-radiographic axial spondyloarthritis
Default screening record
- Infuse 6 mg/kg by intravenous route once at week 0
- Infuse 1.75 mg/kg by intravenous route every 4 weeks not to exceed 300 mg per infusion
- None
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- None
Severe
Moderate
- None
COSENTYX (secukinumab)
- moderate to severe plaque psoriasis
- psoriasis associated with arthritis
- rheumatic disease causing pain & stiffness in backbone
- juvenile enthesitis-related arthritis
- non-radiographic axial spondyloarthritis
- None
- None
More Frequent
Severe
Less Severe
- None
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- None
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Secukinumab
- Severity Level:
2
- Additional Notes: Insufficient human data avail; animal data sug no known developmental tox
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Ankylosing spondylitis | |
| M08.1 | Juvenile ankylosing spondylitis |
| M45 | Ankylosing spondylitis |
| M45.0 | Ankylosing spondylitis of multiple sites in spine |
| M45.1 | Ankylosing spondylitis of occipito-atlanto-axial region |
| M45.2 | Ankylosing spondylitis of cervical region |
| M45.3 | Ankylosing spondylitis of cervicothoracic region |
| M45.4 | Ankylosing spondylitis of thoracic region |
| M45.5 | Ankylosing spondylitis of thoracolumbar region |
| M45.6 | Ankylosing spondylitis lumbar region |
| M45.7 | Ankylosing spondylitis of lumbosacral region |
| M45.8 | Ankylosing spondylitis sacral and sacrococcygeal region |
| M45.9 | Ankylosing spondylitis of unspecified sites in spine |
| Enthesitis-related juvenile idiopathic arthritis | |
| M08.8 | Other juvenile arthritis |
| M08.80 | Other juvenile arthritis, unspecified site |
| M08.85 | Other juvenile arthritis, hip |
| M08.851 | Other juvenile arthritis, right hip |
| M08.852 | Other juvenile arthritis, left hip |
| M08.859 | Other juvenile arthritis, unspecified hip |
| M08.86 | Other juvenile arthritis, knee |
| M08.861 | Other juvenile arthritis, right knee |
| M08.862 | Other juvenile arthritis, left knee |
| M08.869 | Other juvenile arthritis, unspecified knee |
| M08.87 | Other juvenile arthritis, ankle and foot |
| M08.871 | Other juvenile arthritis, right ankle and foot |
| M08.872 | Other juvenile arthritis, left ankle and foot |
| M08.879 | Other juvenile arthritis, unspecified ankle and foot |
| M08.88 | Other juvenile arthritis, other specified site |
| M08.89 | Other juvenile arthritis, multiple sites |
| Moderate to severe plaque psoriasis | |
| L40.0 | Psoriasis vulgaris |
| L40.8 | Other psoriasis |
| L40.9 | Psoriasis, unspecified |
| Non-radiographic axial spondyloarthritis | |
| M45.A | Non-radiographic axial spondyloarthritis |
| M45.A0 | Non-radiographic axial spondyloarthritis of unspecified sites in spine |
| M45.A1 | Non-radiographic axial spondyloarthritis of occipito-atlanto-axial region |
| M45.A2 | Non-radiographic axial spondyloarthritis of cervical region |
| M45.A3 | Non-radiographic axial spondyloarthritis of cervicothoracic region |
| M45.A4 | Non-radiographic axial spondyloarthritis of thoracic region |
| M45.A5 | Non-radiographic axial spondyloarthritis of thoracolumbar region |
| M45.A6 | Non-radiographic axial spondyloarthritis of lumbar region |
| M45.A7 | Non-radiographic axial spondyloarthritis of lumbosacral region |
| M45.A8 | Non-radiographic axial spondyloarthritis of sacral and sacrococcygeal region |
| M45.AB | Non-radiographic axial spondyloarthritis of multiple sites in spine |
| Psoriatic arthritis | |
| L40.5 | Arthropathic psoriasis |
| L40.50 | Arthropathic psoriasis, unspecified |
| L40.51 | Distal interphalangeal psoriatic arthropathy |
| L40.52 | Psoriatic arthritis mutilans |
| L40.53 | Psoriatic spondylitis |
| L40.54 | Psoriatic juvenile arthropathy |
| L40.59 | Other psoriatic arthropathy |
| 0-9 | A-Z |
|---|---|
| L40.0 | Psoriasis vulgaris |
| L40.5 | Arthropathic psoriasis |
| L40.50 | Arthropathic psoriasis, unspecified |
| L40.51 | Distal interphalangeal psoriatic arthropathy |
| L40.52 | Psoriatic arthritis mutilans |
| L40.53 | Psoriatic spondylitis |
| L40.54 | Psoriatic juvenile arthropathy |
| L40.59 | Other psoriatic arthropathy |
| L40.8 | Other psoriasis |
| L40.9 | Psoriasis, unspecified |
| M08.1 | Juvenile ankylosing spondylitis |
| M08.8 | Other juvenile arthritis |
| M08.80 | Other juvenile arthritis, unspecified site |
| M08.85 | Other juvenile arthritis, hip |
| M08.851 | Other juvenile arthritis, right hip |
| M08.852 | Other juvenile arthritis, left hip |
| M08.859 | Other juvenile arthritis, unspecified hip |
| M08.86 | Other juvenile arthritis, knee |
| M08.861 | Other juvenile arthritis, right knee |
| M08.862 | Other juvenile arthritis, left knee |
| M08.869 | Other juvenile arthritis, unspecified knee |
| M08.87 | Other juvenile arthritis, ankle and foot |
| M08.871 | Other juvenile arthritis, right ankle and foot |
| M08.872 | Other juvenile arthritis, left ankle and foot |
| M08.879 | Other juvenile arthritis, unspecified ankle and foot |
| M08.88 | Other juvenile arthritis, other specified site |
| M08.89 | Other juvenile arthritis, multiple sites |
| M45 | Ankylosing spondylitis |
| M45.0 | Ankylosing spondylitis of multiple sites in spine |
| M45.1 | Ankylosing spondylitis of occipito-atlanto-axial region |
| M45.2 | Ankylosing spondylitis of cervical region |
| M45.3 | Ankylosing spondylitis of cervicothoracic region |
| M45.4 | Ankylosing spondylitis of thoracic region |
| M45.5 | Ankylosing spondylitis of thoracolumbar region |
| M45.6 | Ankylosing spondylitis lumbar region |
| M45.7 | Ankylosing spondylitis of lumbosacral region |
| M45.8 | Ankylosing spondylitis sacral and sacrococcygeal region |
| M45.9 | Ankylosing spondylitis of unspecified sites in spine |
| M45.A | Non-radiographic axial spondyloarthritis |
| M45.A0 | Non-radiographic axial spondyloarthritis of unspecified sites in spine |
| M45.A1 | Non-radiographic axial spondyloarthritis of occipito-atlanto-axial region |
| M45.A2 | Non-radiographic axial spondyloarthritis of cervical region |
| M45.A3 | Non-radiographic axial spondyloarthritis of cervicothoracic region |
| M45.A4 | Non-radiographic axial spondyloarthritis of thoracic region |
| M45.A5 | Non-radiographic axial spondyloarthritis of thoracolumbar region |
| M45.A6 | Non-radiographic axial spondyloarthritis of lumbar region |
| M45.A7 | Non-radiographic axial spondyloarthritis of lumbosacral region |
| M45.A8 | Non-radiographic axial spondyloarthritis of sacral and sacrococcygeal region |
| M45.AB | Non-radiographic axial spondyloarthritis of multiple sites in spine |
Formulary Reference Tool