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COSENTYX (2 SYRINGES) (secukinumab)
- moderate to severe plaque psoriasis
- psoriasis associated with arthritis
- rheumatic disease causing pain & stiffness in backbone
- juvenile enthesitis-related arthritis
- non-radiographic axial spondyloarthritis
150 mg/mL subcutaneous syringe
- Inject 2 milliliters (300 mg) by subcutaneous route every 4 weeks in the abdomen, thigh, or outer area of upper arm (rotate sites)
75 mg/0.5 mL subcutaneous syringe
- Dosage information is not available
Cosentyx 150 mg/mL subcutaneous syringe
- Inject 2 milliliters (300 mg) by subcutaneous route every 4 weeks in the abdomen, thigh, or outer area of upper arm (rotate sites)
Cosentyx 75 mg/0.5 mL subcutaneous syringe
- Dosage information is not available
Cosentyx 300 mg/2 Syringes (150 mg/mL) subcutaneous
- Inject 2 milliliters (300 mg) by subcutaneous route every 4 weeks in the abdomen, thigh, or outer area of upper arm (rotate sites)
Default screening record
- Inject 1 milliliter (150 mg) by subcutaneous route every 4 weeks in the abdomen, thigh, or outer area of upper arm (rotate sites)
- Inject 1 milliliter (150 mg) by subcutaneous route once weekly for 5 weeks, followed by 1 ml (150 mg) every 4 weeks in the abdomen, thighs,or outer area of upper arm rotating injection sites
- Inject 2 milliliters (300 mg) by subcutaneous route once weekly for 5Weeks, followed by 2 ml (300 mg) every 4 weeks in the abdomen, thighs, or outer area of upper arm rotating injection sites
- Inject 2 milliliters (300 mg) by subcutaneous route every 4 weeks in the abdomen, thigh, or outer area of upper arm (rotate sites)
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- BCG vaccine, live (PF)
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- tofacitinib
- typhoid vaccine
- Tysabri
- varicella virus vacc live (PF)
- Varivax (pf)
- Vivotif Berna Vaccine
- Xeljanz
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- None
Severe
Moderate
- None
- Active tuberculosis
Contraindicated
- Crohn's disease
- Inactive tuberculosis
- Severe infection
Severe
Moderate
- None
COSENTYX (2 SYRINGES) (secukinumab)
- moderate to severe plaque psoriasis
- psoriasis associated with arthritis
- rheumatic disease causing pain & stiffness in backbone
- juvenile enthesitis-related arthritis
- non-radiographic axial spondyloarthritis
- None
- Diarrhea
- Pharyngitis
- Upper respiratory infection
More Frequent
Severe
Less Severe
- Colitis
- Gastritis
- Infection
- Acute abdominal pain
- Herpes simplex infection
- Injection site sequelae
- Mucocutaneous candidiasis
- Rhinitis
- Rhinorrhea
- Urticaria
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Anaphylaxis
- Bloody stools
- Hypersensitivity drug reaction
- Inflammatory bowel disease
- Neutropenic disorder
Less Severe
- Conjunctivitis
- Impetigo
- Oral candidiasis
- Otitis
- Sinusitis
- Tinea pedis
- Tonsillitis
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Secukinumab
Safety and effectiveness not established in pediatric patients < 2 years.
- 1 Day – 2 Years
- Safety and effectiveness not established in pediatric patients < 2 years.
Secukinumab
- Severity Level:
2
- Additional Notes: Insufficient human data avail; animal data sug no known developmental tox
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Secukinumab
Insufficient human data available
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
Ankylosing spondylitis | |
M08.1 | Juvenile ankylosing spondylitis |
M45 | Ankylosing spondylitis |
M45.0 | Ankylosing spondylitis of multiple sites in spine |
M45.1 | Ankylosing spondylitis of occipito-atlanto-axial region |
M45.2 | Ankylosing spondylitis of cervical region |
M45.3 | Ankylosing spondylitis of cervicothoracic region |
M45.4 | Ankylosing spondylitis of thoracic region |
M45.5 | Ankylosing spondylitis of thoracolumbar region |
M45.6 | Ankylosing spondylitis lumbar region |
M45.7 | Ankylosing spondylitis of lumbosacral region |
M45.8 | Ankylosing spondylitis sacral and sacrococcygeal region |
M45.9 | Ankylosing spondylitis of unspecified sites in spine |
Enthesitis-related juvenile idiopathic arthritis | |
M08.8 | Other juvenile arthritis |
M08.80 | Other juvenile arthritis, unspecified site |
M08.85 | Other juvenile arthritis, hip |
M08.851 | Other juvenile arthritis, right hip |
M08.852 | Other juvenile arthritis, left hip |
M08.859 | Other juvenile arthritis, unspecified hip |
M08.86 | Other juvenile arthritis, knee |
M08.861 | Other juvenile arthritis, right knee |
M08.862 | Other juvenile arthritis, left knee |
M08.869 | Other juvenile arthritis, unspecified knee |
M08.87 | Other juvenile arthritis, ankle and foot |
M08.871 | Other juvenile arthritis, right ankle and foot |
M08.872 | Other juvenile arthritis, left ankle and foot |
M08.879 | Other juvenile arthritis, unspecified ankle and foot |
M08.88 | Other juvenile arthritis, other specified site |
M08.89 | Other juvenile arthritis, multiple sites |
Moderate to severe plaque psoriasis | |
L40.0 | Psoriasis vulgaris |
L40.8 | Other psoriasis |
L40.9 | Psoriasis, unspecified |
Non-radiographic axial spondyloarthritis | |
M45.A | Non-radiographic axial spondyloarthritis |
M45.A0 | Non-radiographic axial spondyloarthritis of unspecified sites in spine |
M45.A1 | Non-radiographic axial spondyloarthritis of occipito-atlanto-axial region |
M45.A2 | Non-radiographic axial spondyloarthritis of cervical region |
M45.A3 | Non-radiographic axial spondyloarthritis of cervicothoracic region |
M45.A4 | Non-radiographic axial spondyloarthritis of thoracic region |
M45.A5 | Non-radiographic axial spondyloarthritis of thoracolumbar region |
M45.A6 | Non-radiographic axial spondyloarthritis of lumbar region |
M45.A7 | Non-radiographic axial spondyloarthritis of lumbosacral region |
M45.A8 | Non-radiographic axial spondyloarthritis of sacral and sacrococcygeal region |
M45.AB | Non-radiographic axial spondyloarthritis of multiple sites in spine |
Psoriatic arthritis | |
L40.5 | Arthropathic psoriasis |
L40.50 | Arthropathic psoriasis, unspecified |
L40.51 | Distal interphalangeal psoriatic arthropathy |
L40.52 | Psoriatic arthritis mutilans |
L40.53 | Psoriatic spondylitis |
L40.54 | Psoriatic juvenile arthropathy |
L40.59 | Other psoriatic arthropathy |
0-9 | A-Z |
---|---|
L40.0 | Psoriasis vulgaris |
L40.5 | Arthropathic psoriasis |
L40.50 | Arthropathic psoriasis, unspecified |
L40.51 | Distal interphalangeal psoriatic arthropathy |
L40.52 | Psoriatic arthritis mutilans |
L40.53 | Psoriatic spondylitis |
L40.54 | Psoriatic juvenile arthropathy |
L40.59 | Other psoriatic arthropathy |
L40.8 | Other psoriasis |
L40.9 | Psoriasis, unspecified |
M08.1 | Juvenile ankylosing spondylitis |
M08.8 | Other juvenile arthritis |
M08.80 | Other juvenile arthritis, unspecified site |
M08.85 | Other juvenile arthritis, hip |
M08.851 | Other juvenile arthritis, right hip |
M08.852 | Other juvenile arthritis, left hip |
M08.859 | Other juvenile arthritis, unspecified hip |
M08.86 | Other juvenile arthritis, knee |
M08.861 | Other juvenile arthritis, right knee |
M08.862 | Other juvenile arthritis, left knee |
M08.869 | Other juvenile arthritis, unspecified knee |
M08.87 | Other juvenile arthritis, ankle and foot |
M08.871 | Other juvenile arthritis, right ankle and foot |
M08.872 | Other juvenile arthritis, left ankle and foot |
M08.879 | Other juvenile arthritis, unspecified ankle and foot |
M08.88 | Other juvenile arthritis, other specified site |
M08.89 | Other juvenile arthritis, multiple sites |
M45 | Ankylosing spondylitis |
M45.0 | Ankylosing spondylitis of multiple sites in spine |
M45.1 | Ankylosing spondylitis of occipito-atlanto-axial region |
M45.2 | Ankylosing spondylitis of cervical region |
M45.3 | Ankylosing spondylitis of cervicothoracic region |
M45.4 | Ankylosing spondylitis of thoracic region |
M45.5 | Ankylosing spondylitis of thoracolumbar region |
M45.6 | Ankylosing spondylitis lumbar region |
M45.7 | Ankylosing spondylitis of lumbosacral region |
M45.8 | Ankylosing spondylitis sacral and sacrococcygeal region |
M45.9 | Ankylosing spondylitis of unspecified sites in spine |
M45.A | Non-radiographic axial spondyloarthritis |
M45.A0 | Non-radiographic axial spondyloarthritis of unspecified sites in spine |
M45.A1 | Non-radiographic axial spondyloarthritis of occipito-atlanto-axial region |
M45.A2 | Non-radiographic axial spondyloarthritis of cervical region |
M45.A3 | Non-radiographic axial spondyloarthritis of cervicothoracic region |
M45.A4 | Non-radiographic axial spondyloarthritis of thoracic region |
M45.A5 | Non-radiographic axial spondyloarthritis of thoracolumbar region |
M45.A6 | Non-radiographic axial spondyloarthritis of lumbar region |
M45.A7 | Non-radiographic axial spondyloarthritis of lumbosacral region |
M45.A8 | Non-radiographic axial spondyloarthritis of sacral and sacrococcygeal region |
M45.AB | Non-radiographic axial spondyloarthritis of multiple sites in spine |
Formulary Reference Tool