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ENALAPRIL MALEATE (ENALAPRIL MALEATE)
- Asymptomatic left ventricular dysfunction
- Chronic heart failure
- Hypertension
10 mg tablet
- 1 tablet (10 mg) by oral route once daily
2.5 mg tablet
- 1 tablet (2.5 mg) by oral route once daily
20 mg tablet
- 1 tablet (20 mg) by oral route once daily
5 mg tablet
- 1 tablet (5 mg) by oral route once daily
10 mg tablet
- 1 tablet (10 mg) by oral route once daily
2.5 mg tablet
- 1 tablet (2.5 mg) by oral route once daily
20 mg tablet
- 1 tablet (20 mg) by oral route once daily
5 mg tablet
- 1 tablet (5 mg) by oral route once daily
Chronic heart failure
- 2 tablets (5 mg) by oral route 2 times per day
- 1 tablet (5 mg) by oral route 2 times per day
- 2 tablets (5 mg) by oral route once daily
- 1 tablet (5 mg) by oral route once daily
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route 2 times per day
- 2 tablets (10 mg) by oral route 2 times per day
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route 2 times per day
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route 2 times per day
- 1 tablet (2.5 mg) by oral route once daily
- 1 tablet (2.5 mg) by oral route 2 times per day
Hypertension
- 2 tablets (5 mg) by oral route 2 times per day
- 1 tablet (5 mg) by oral route 2 times per day
- 2 tablets (5 mg) by oral route once daily
- 1 tablet (5 mg) by oral route once daily
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route 2 times per day
- 2 tablets (10 mg) by oral route 2 times per day
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route 2 times per day
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route 2 times per day
- 2 tablets (40 mg) by oral route once daily
- 1 tablet (2.5 mg) by oral route once daily
- 1 tablet (2.5 mg) by oral route 2 times per day
- None
Contraindicated
- aliskiren
- aliskiren-amlodipin-hcthiazide
- aliskiren-amlodipine
- aliskiren-hydrochlorothiazide
- Amturnide
- Curad Enema
- Disposable Enema
- Enema
- Enema Disposable
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- lithium carbonate
- lithium citrate
- Lithobid
- Oral Saline Laxative
- Osmoprep
- Phosphate Laxative
- Preparation Cleansing
- Ready-to-use Enema
- sod phos mono-sod phos dibasic
- sodium phosphates
- Tekamlo
- Tekturna
- Tekturna Hct
Severe
Moderate
- Added Strength Headache Relief
- Added Strength Pain Reliever
- Alka-seltzer
- Alka-seltzer Extra Strength
- Alka-seltzer Original
- Alka-seltzer Plus C/c(pe,dm)
- Alka-seltzer Plus Cold (pe)
- Alka-seltzer Plus Day-night
- Alka-seltzer Plus Night
- Alka-seltzer Pm
- Anacin
- Anacin Maximum Strength
- Analgesic
- Angeliq
- Antacid & Pain Relief
- ASA-acetaminophen-caff-buffers
- ASA-acetaminophen-salicyl-caff
- Ascomp With Codeine
- Aspir-trin
- aspirin
- aspirin, buffered
- aspirin-acetaminophen-caffeine
- aspirin-caffeine
- aspirin-diphenhydramine
- aspirin-diphenhydramine citrat
- aspirin-sod bicarb-citric acid
- Azasan
- azathioprine
- azathioprine sodium
- Back & Body Pain Reliever
- Bactrim
- Bactrim Ds
- Bayer Advanced
- Bayer Aspirin
- Bayer Aspirin (with Caffeine)
- Bayer Back & Body
- Bayer Plus Extra Strength
- Bayer Pm
- Bc
- Bc Arthritis
- Beyaz
- Buffered Aspirin
- Bufferin
- bumetanide
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-aspirin-caffeine
- carisoprodol-ASA-codeine
- carisoprodol-aspirin
- chlorphen-phenyleph-DM-aspirin
- chlorphenir-phenylephrn-aspirn
- codeine-butalbital-ASA-caff
- Cold Relief
- Cold Relief Plus
- Demadex
- dihydrocodeine-aspirin-caff
- doxylamine-phenylep-DM-aspirin
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- E.c. Prin
- Ecotrin
- Efferves Pain Relief Antacid
- Effervescent Antacid
- Effervescent Pain Relief
- Effervescent Pain Reliever
- Endodan
- ethacrynate sodium
- Excedrin Extra Strength
- Excedrin Migraine
- Extra Strength Bayer
- Fiorinal
- Fiorinal-codeine #3
- furosemide
- Gianvi (28)
- Goody's Extra Strength
- Goody's Migraine Relief
- Headache Formula
- Headache Formula Added Str
- Headache Relief
- Imuran
- Lasix
- Levacet
- Lite Coat Aspirin
- Loryna (28)
- Medi-seltzer
- mercaptopurine
- Migraine Formula
- Migraine Pain Reliever
- Migraine Relief
- Ocella
- Orphenadrine Compound Forte
- Orphenadrine Compound-ds
- orphenadrine-ASA-caffeine
- oxycodone-aspirin
- Pain Relief
- Pain Relief Extra Strength
- Pain Reliever
- Pain Reliever Extra Strength
- Pain Reliever Plus
- Pain-off
- Pamprin Max
- PE-DM-ASA/doxyla-PE-DM-ASA
- Percodan
- Primsol
- Purinethol
- Safyral
- Sodium Edecrin
- sulfamethoxazole-trimethoprim
- Sulfatrim
- Super Pain Relief
- Syeda
- Synalgos-dc
- torsemide
- Tri-buffered Aspirin
- trimethoprim
- Vanquish
- Vestura (28)
- Yasmin (28)
- Yaz 28
- Zarah
- Angioedema
- Hereditary angioedema
- Pregnancy
Contraindicated
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Chronic kidney disease stage 5 (failure) GFr<15 ml/min
- Hemodialysis with high-flux membrane
- Hyperkalemia
- Hyponatremia
- Hypotension
- Renal artery stenosis
Severe
Moderate
- Aortic valve stenosis
- Bone marrow depression
- Cerebrovascular insufficiency
- Disease of liver
- Hypertrophic cardiomyopathy
- Immunosuppression
- Neutropenic disorder
ENALAPRIL MALEATE (ENALAPRIL MALEATE)
- Asymptomatic left ventricular dysfunction
- Chronic heart failure
- Hypertension
- Hypotension
- Cough
- Dizziness
More Frequent
Severe
Less Severe
- Fever
- Hyperkalemia
- Arthralgias
- Bronchitis
- Diarrhea
- Dysgeusia
- Dyspnea
- Fatigue
- General weakness
- Headache disorder
- Orthostatic hypotension
- Skin rash
- Syncope
- Vertigo
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Acute pancreatitis
- Acute renal failure
- Agranulocytosis
- Anaphylaxis
- Angioedema
- Atrial fibrillation
- Bradycardia
- Bronchospastic pulmonary disease
- Chest pain
- Drug-induced hepatitis
- Eosinophilia
- Eosinophilic pneumonia
- Erythema multiforme
- Exfoliative dermatitis
- Head and neck angioedema
- Ileus
- Intestinal angioedema
- Laryngeal edema
- Leukocytosis
- Myositis
- Neutropenic disorder
- Obstructive hyperbilirubinemia
- Pemphigus
- Pharyngeal edema
- Pulmonary edema
- Pulmonary thromboembolism
- Stevens-johnson syndrome
- Tachycardia
- Thrombocytopenic disorder
- Tongue swelling
- Toxic epidermal necrolysis
- Vasculitis
Less Severe
- Acute confusion
- Anorexia
- Ataxia
- Black tarry stools
- Blurred vision
- Conjunctivitis
- Constipation
- Cramps
- Depression
- Drowsy
- Dyspepsia
- Erectile dysfunction
- Flushing
- Glossitis
- Gynecomastia
- Hyperhidrosis
- Loss of sense of smell
- Myalgias
- Pruritus of skin
- Raynaud's phenomenon
- Skin photosensitivity
- Stomatitis
- Tinnitus
- Urticaria
Contraindicated
None
Severe Precaution
Enalapril (Oral)
Not recommended in neonates or with CrCL <30mL/min.
- 1 Day – 29 Days
- Not recommended in neonates or with CrCL <30mL/min.
Management or Monitoring Precaution
None
Enalapril
- Severity Level:
1
- Additional Notes: Fetal death/morbidity w/use in 2nd & 3rd trimester, stop when pregnancy detected
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Enalapril
Limited data suggest minimal excretion resulting in no adv effects in infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest minimal excretion resulting in no adv effects in infant |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Enalapril
Cardiovascular-Monitor for hypotension. Renal-May increase serum creatinine. Hyperkalemia risk increases with renal insufficiency. Adjust dose for CrCL <31 mL/minute.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor right away.
| Asymptomatic left ventricular dysfunction | |
| I51.9 | Heart disease, unspecified |
| Chronic heart failure | |
| I50.22 | Chronic systolic (congestive) heart failure |
| I50.32 | Chronic diastolic (congestive) heart failure |
| I50.42 | Chronic combined systolic (congestive) and diastolic (congestive) heart failure |
| I50.812 | Chronic right heart failure |
| I50.814 | Right heart failure due to left heart failure |
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| I50.22 | Chronic systolic (congestive) heart failure |
| I50.32 | Chronic diastolic (congestive) heart failure |
| I50.42 | Chronic combined systolic (congestive) and diastolic (congestive) heart failure |
| I50.812 | Chronic right heart failure |
| I50.814 | Right heart failure due to left heart failure |
| I51.9 | Heart disease, unspecified |
Formulary Reference Tool