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BISOPROLOL FUMARATE (BISOPROLOL FUMARATE)
- Hypertension
10 mg tablet
- 1 tablet (10 mg) by oral route once daily
5 mg tablet
- 1 tablet (5 mg) by oral route once daily
Hypertension
- 1 tablet (5 mg) by oral route once daily
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route once daily
- one-half tablet (2.5 mg) by oral route once daily
- None
Contraindicated
- Catapres
- Catapres-tts-1
- Catapres-tts-2
- Catapres-tts-3
- clonidine
- clonidine (PF)
- clonidine-chlorthalidone
- Clorpres
- Corlopam
- Duraclon (pf)
- fenoldopam
- fingolimod
- Gilenya
- Kapvay
Severe
Moderate
- Adalat Cc
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Afeditab Cr
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- Anaprox
- Anaprox Ds
- Ansaid
- Calan
- Calan Sr
- Caldolor
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- Duexis
- Ec-naprosyn
- Feldene
- Flanax
- flurbiprofen
- hydrocodone-ibuprofen
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- Matzim La
- Medi-profen
- Mediproxen
- meloxicam
- Midol (naproxen)
- Mobic
- Motrin Ib
- Motrin Pm
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- Neoprofen (ibuprofen Lysn)(pf)
- Nifedical Xl
- nifedipine
- piroxicam
- Procardia
- Procardia Xl
- Provil
- pseudoephedrine-ibuprofen
- Reprexain
- Sinus & Cold-d
- sulindac
- Tarka
- Taztia Xt
- Tiazac
- trandolapril-verapamil
- verapamil
- Verelan
- Verelan Pm
- Vicoprofen
- Vimovo
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Acute asthma attack
- Acute decompensated heart failure
- Cardiogenic shock
- Complete atrioventricular block
- Pregnancy
- Second degree atrioventricular heart block
Contraindicated
- Pheochromocytoma
- Renal disease with moderate to severe impairment
- Severe chronic obstructive pulmonary disease
- Sinus bradycardia
Severe
Moderate
- Asthma
- Depression
- Diabetes mellitus
- Disease of liver
- Myasthenia gravis
- Peripheral vascular disease
- Psoriasis
- Raynaud's phenomenon
BISOPROLOL FUMARATE (BISOPROLOL FUMARATE)
- Hypertension
- None
- Fatigue
- General weakness
More Frequent
Severe
Less Severe
- Arthralgias
- Bronchospastic pulmonary disease
- Chest pain
- Diarrhea
- Drowsy
- Dyspnea
- Insomnia
- Nasal congestion
- Nausea
- Nervousness
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute confusion
- Agranulocytosis
- Bradycardia
- Cardiac arrhythmia
- Chronic heart failure
- Gastritis
- Gout
- Hallucinations
- Ischemic colitis
- Laryngismus
- Leukopenia
- Orthostatic hypotension
- Peptic ulcer
- Peripheral vasoconstriction
- Peyronie's disease
- Psoriasiform eruption
- Purpura
- Renal colic
- Thrombocytopenic disorder
Less Severe
- Abdominal pain with cramps
- Abnormal hepatic function tests
- Constipation
- Cramps
- Cystitis
- Dizziness
- Dream disorder
- Dry eye
- Dysgeusia
- Dyspepsia
- Erectile dysfunction
- Hearing loss
- Hypesthesia
- Libido changes
- Mood changes
- Ocular irritation
- Polyuria
- Pruritus of skin
- Symptoms of anxiety
- Tinnitus
- Upper respiratory infection
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Bisoprolol
Safety and efficacy not established in pediatrics.
- 1 Day – 18 Years
- Safety and efficacy not established in pediatrics.
Bisoprolol
- Severity Level:
1
- Additional Notes: Fda c, reports of intrauterine growth retard;monitor fetus/infant for b-blockade
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Bisoprolol
Excret in animal studies;Monitor for signs of b-block:Bradycardia,hypotension
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Excret in animal studies;Monitor for signs of b-block:Bradycardia,hypotension |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Bisoprolol
Cardiovascular-Minimize dose to decrease dizziness and falls. Renal-Renal elimination; use caution in starting dose and dose escalation.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool