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ALMOTRIPTAN MALATE (ALMOTRIPTAN MALATE)
- Migraine
12.5 mg tablet
- 1 tablet (12.5 mg) by oral route ; if headache returns, the dosemay be repeated after 2 hours, no more than two doses per 24 hrs
6.25 mg tablet
- 1 tablet (6.25 mg) by oral route once ; if headache returns, thedose may be repeated after 2 hours, no more than two doses per 24 hrs
Migraine
- 2 tablets (12.5 mg) by oral route ; if headache returns, the dose may be repeated after 2 hours, no more than two doses per 24 hrs
- 1 tablet (12.5 mg) by oral route ; if headache returns, the dosemay be repeated after 2 hours, but no more than two doses should be given within a 24-hour period.
- 2 tablets (12.5 mg) by oral route ; if headache returns, the dose may be repeated after 2 hours, but no more than two doses should be given within a 24-hour period.
- 1 tablet (12.5 mg) by oral route ; if headache returns, the dosemay be repeated after 2 hours, no more than two doses per 24 hrs
- 1 tablet (6.25 mg) by oral route once ; if headache returns, thedose may be repeated after 2 hours, no more than two doses per 24 hrs
- 1 tablet (6.25 mg) by oral route once ; if headache returns, thedose may be repeated after 2 hours, but no more than two doses shouldbe given within a 24-hour period.
- bromocriptine
- Cafergot
- Cycloset
- D.h.e.45
- dihydroergotamine
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- methylergonovine
- Migergot
- Migranal
- Parlodel
Contraindicated
- Conzip
- Nucynta
- Nucynta Er
- Synapryn
- tapentadol
- tramadol
- tramadol-acetaminophen
- tramadol-glucosamine
- Ultracet
- Ultram
- Ultram Er
Severe
Moderate
- Azilect
- Brintellix
- Brisdelle
- Celexa
- citalopram
- Cymbalta
- desvenlafaxine
- desvenlafaxine fumarate
- desvenlafaxine succinate
- duloxetine
- Effexor Xr
- Eldepryl
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- escitalopram oxalate
- Fetzima
- fluoxetine
- fluvoxamine
- isocarboxazid
- itraconazole
- Kaletra
- ketoconazole
- Khedezla
- levomilnacipran
- Lexapro
- linezolid
- lopinavir-ritonavir
- Luvox Cr
- Marplan
- Matulane
- methylene blue (antidote)
- milnacipran
- Nardil
- Norvir
- Norvir Soft Gelatin
- olanzapine-fluoxetine
- Onmel
- Parnate
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- Pexeva
- phenelzine
- Pristiq
- procarbazine
- Prozac
- Prozac Weekly
- rasagiline
- ritonavir
- Sarafem
- Savella
- selegiline HCl
- sertraline
- Sporanox
- Sporanox Pulsepak
- Symbyax
- tranylcypromine
- venlafaxine
- Viibryd
- vilazodone
- vortioxetine
- Zelapar
- Zoloft
- Zyvox
- Acute myocardial infarction
- Angina
- Cerebral ischemia
- Cerebrovascular accident
- Coronary artery disease
- Hemiplegic migraine
- Myocardial ischemia
- Peripheral vascular disease
- Prinzmetal angina
- Serotonin syndrome
- Severe uncontrolled hypertension
Contraindicated
- Cardiac arrhythmia
- Disease of liver
- Familial history of ischemic heart disease
- Increased cardiovascular event risk
- Ischemic bowel disease
- Severe renal impairment
Severe
Moderate
- Raynaud's phenomenon
ALMOTRIPTAN MALATE (ALMOTRIPTAN MALATE)
- Migraine
- None
- Dizziness
- Drowsy
- Headache disorder
- Nausea
- Paresthesia
- Xerostomia
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Chest pain
- Conjunctivitis
- Dyspnea
- Erythema
- Laryngismus
- Neck pain
- Ocular irritation
- Palpitations
- Pruritus of skin
- Skin rash
- Tachycardia
- Abdominal pain with cramps
- Back pain
- Bronchitis
- Chills
- Diarrhea
- Dysgeusia
- Dysmenorrhea
- Dyspepsia
- Earache
- Epistaxis
- Fatigue
- General weakness
- Hyperacusis
- Hyperhidrosis
- Insomnia
- Medication overuse headache
- Muscle weakness
- Myalgias
- Nervousness
- Pharyngitis
- Rhinitis
- Sinusitis
- Symptoms of anxiety
- Tremor
- Vasodilation of blood vessels
- Vertigo
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute bacterial otitis media
- Acute myocardial infarction
- Anaphylaxis
- Angina
- Angioedema
- Cerebrovascular accident
- Colitis
- Coronary artery spasm
- Fever
- Gastritis
- Gastroenteritis
- Gastroesophageal reflux disease
- Hemiplegia
- Hypertension
- Hyperventilation
- Ischemic bowel disease
- Myocardial ischemia
- Ocular pain
- Scotomata
- Seizure disorder
- Serotonin syndrome
- Syncope
- Tongue swelling
- Ventricular fibrillation
Less Severe
- Acute confusion
- Arthralgias
- Arthritis
- Ataxia
- Blepharospasm
- Concentration difficulty
- Depression
- Diplopia
- Dry eye
- Euphoria
- Hyperglycemia
- Hyperreflexia
- Hypertonia
- Hypesthesia
- Laryngitis
- Malaise
- Mastalgia
- Myopathy
- Nightmares
- Nystagmus
- Parosmia
- Peripheral sensory neuropathy
- Sensation of cold
- Sialorrhea
- Skin photosensitivity
- Sneezing
- Tinnitus
- Visual changes
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Almotriptan
Safety and efficacy not established age < 12 years.
- 1 Day – 12 Years
- Safety and efficacy not established age < 12 years.
Almotriptan
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Almotriptan
Insufficient human data available; drug excreted in rat studies
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available; drug excreted in rat studies |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Almotriptan
Renal-The drug is partially cleared renally. Reduce dose to 6.25mg for severe renal impairment (CrCL<30 mL/min.) Hepatic-Elderly patients are more likely to have decreased hepatic function thus potentially decreasing drug clearance. Cardiovascular-Hypertensive effects may be more pronounced in the elderly and increase the risk for cardiovascular events in those with cardiovascular disease. Avoid use of the drug in any patient with a cerebrovascular syndrome.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Migraine | |
| G43 | Migraine |
| G43.0 | Migraine without aura |
| G43.00 | Migraine without aura, not intractable |
| G43.001 | Migraine without aura, not intractable, with status migrainosus |
| G43.009 | Migraine without aura, not intractable, without status migrainosus |
| G43.01 | Migraine without aura, intractable |
| G43.011 | Migraine without aura, intractable, with status migrainosus |
| G43.019 | Migraine without aura, intractable, without status migrainosus |
| G43.1 | Migraine with aura |
| G43.10 | Migraine with aura, not intractable |
| G43.101 | Migraine with aura, not intractable, with status migrainosus |
| G43.109 | Migraine with aura, not intractable, without status migrainosus |
| G43.11 | Migraine with aura, intractable |
| G43.111 | Migraine with aura, intractable, with status migrainosus |
| G43.119 | Migraine with aura, intractable, without status migrainosus |
| G43.4 | Hemiplegic migraine |
| G43.40 | Hemiplegic migraine, not intractable |
| G43.41 | Hemiplegic migraine, intractable |
| G43.7 | Chronic migraine without aura |
| G43.70 | Chronic migraine without aura, not intractable |
| G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
| G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
| G43.71 | Chronic migraine without aura, intractable |
| G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
| G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
| G43.8 | Other migraine |
| G43.80 | Other migraine, not intractable |
| G43.801 | Other migraine, not intractable, with status migrainosus |
| G43.809 | Other migraine, not intractable, without status migrainosus |
| G43.81 | Other migraine, intractable |
| G43.811 | Other migraine, intractable, with status migrainosus |
| G43.819 | Other migraine, intractable, without status migrainosus |
| G43.82 | Menstrual migraine, not intractable |
| G43.821 | Menstrual migraine, not intractable, with status migrainosus |
| G43.829 | Menstrual migraine, not intractable, without status migrainosus |
| G43.83 | Menstrual migraine, intractable |
| G43.831 | Menstrual migraine, intractable, with status migrainosus |
| G43.839 | Menstrual migraine, intractable, without status migrainosus |
| G43.9 | Migraine, unspecified |
| G43.90 | Migraine, unspecified, not intractable |
| G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
| G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
| G43.91 | Migraine, unspecified, intractable |
| G43.911 | Migraine, unspecified, intractable, with status migrainosus |
| G43.919 | Migraine, unspecified, intractable, without status migrainosus |
| G43.B | Ophthalmoplegic migraine |
| G43.B0 | Ophthalmoplegic migraine, not intractable |
| G43.B1 | Ophthalmoplegic migraine, intractable |
| G43.C | Periodic headache syndromes in child or adult |
| G43.C0 | Periodic headache syndromes in child or adult, not intractable |
| G43.C1 | Periodic headache syndromes in child or adult, intractable |
| G43.D | Abdominal migraine |
| G43.D0 | Abdominal migraine, not intractable |
| G43.D1 | Abdominal migraine, intractable |
| 0-9 | A-Z |
|---|---|
| G43 | Migraine |
| G43.0 | Migraine without aura |
| G43.00 | Migraine without aura, not intractable |
| G43.001 | Migraine without aura, not intractable, with status migrainosus |
| G43.009 | Migraine without aura, not intractable, without status migrainosus |
| G43.01 | Migraine without aura, intractable |
| G43.011 | Migraine without aura, intractable, with status migrainosus |
| G43.019 | Migraine without aura, intractable, without status migrainosus |
| G43.1 | Migraine with aura |
| G43.10 | Migraine with aura, not intractable |
| G43.101 | Migraine with aura, not intractable, with status migrainosus |
| G43.109 | Migraine with aura, not intractable, without status migrainosus |
| G43.11 | Migraine with aura, intractable |
| G43.111 | Migraine with aura, intractable, with status migrainosus |
| G43.119 | Migraine with aura, intractable, without status migrainosus |
| G43.4 | Hemiplegic migraine |
| G43.40 | Hemiplegic migraine, not intractable |
| G43.41 | Hemiplegic migraine, intractable |
| G43.7 | Chronic migraine without aura |
| G43.70 | Chronic migraine without aura, not intractable |
| G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
| G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
| G43.71 | Chronic migraine without aura, intractable |
| G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
| G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
| G43.8 | Other migraine |
| G43.80 | Other migraine, not intractable |
| G43.801 | Other migraine, not intractable, with status migrainosus |
| G43.809 | Other migraine, not intractable, without status migrainosus |
| G43.81 | Other migraine, intractable |
| G43.811 | Other migraine, intractable, with status migrainosus |
| G43.819 | Other migraine, intractable, without status migrainosus |
| G43.82 | Menstrual migraine, not intractable |
| G43.821 | Menstrual migraine, not intractable, with status migrainosus |
| G43.829 | Menstrual migraine, not intractable, without status migrainosus |
| G43.83 | Menstrual migraine, intractable |
| G43.831 | Menstrual migraine, intractable, with status migrainosus |
| G43.839 | Menstrual migraine, intractable, without status migrainosus |
| G43.9 | Migraine, unspecified |
| G43.90 | Migraine, unspecified, not intractable |
| G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
| G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
| G43.91 | Migraine, unspecified, intractable |
| G43.911 | Migraine, unspecified, intractable, with status migrainosus |
| G43.919 | Migraine, unspecified, intractable, without status migrainosus |
| G43.B | Ophthalmoplegic migraine |
| G43.B0 | Ophthalmoplegic migraine, not intractable |
| G43.B1 | Ophthalmoplegic migraine, intractable |
| G43.C | Periodic headache syndromes in child or adult |
| G43.C0 | Periodic headache syndromes in child or adult, not intractable |
| G43.C1 | Periodic headache syndromes in child or adult, intractable |
| G43.D | Abdominal migraine |
| G43.D0 | Abdominal migraine, not intractable |
| G43.D1 | Abdominal migraine, intractable |
Formulary Reference Tool