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MINOXIDIL (MINOXIDIL)
- Alopecia
- Hypertension
- Rogaine Topical Solution
- Rogaine Extra Strength For Men Topical Solution
- Minoxidil Topical Solution
- Minoxidil Topical Soln
- Minoxidil Tablet
- Hair Regrowth Treatment Topical Solution
- Hair Regrowth Treatment Topical Soln
- By Indication
2 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
Extra Strength for Men 5 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
2 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
5 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
2 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
5 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
10 mg tablet
- 1 tablet (10 mg) by oral route once daily
2.5 mg tablet
- 2 tablets (5 mg) by oral route once daily
2 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
5 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
Treatment 2 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
Treatment 5 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
2 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
5 % topical solution
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
Alopecia
- Apply 1 milliliter by topical route 2 times per day , every day, directly onto the scalp in the hair loss area
Hypertension
- 2 tablets (5 mg) by oral route once daily
- 2 tablets (5 mg) by oral route 2 times per day
- 4 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route 2 times per day
- 1 tablet (10 mg) by oral route once daily
- 4 tablets (10 mg) by oral route 2 times per day
- 2 tablets (20 mg) by oral route 2 times per day
- 2 tablets (20 mg) by oral route once daily
- 4 tablets (40 mg) by oral route once daily
- None
Contraindicated
- None
Severe
Moderate
- None
- Dermatosis of the scalp
- Pheochromocytoma
Contraindicated
- 30 day risk period post-myocardial infarction
- Angina
- Chronic heart failure
- Pericardial effusion
- Pericardial tamponade
- Pericarditis
Severe
Moderate
- Cerebrovascular disorder
- Kidney disease with reduction in GFR
MINOXIDIL (MINOXIDIL)
- Alopecia
- Hypertension
- Body fluid retention
- Cardiac arrhythmia
- Edema
- Hirsutism
More Frequent
Severe
Less Severe
- Angina
- Chest pain
- Dermatitis due to topical drug
- Pericarditis
- Pruritus of skin
- Skin rash
- Urticaria
- Dry skin
- Erythema
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal ECG
- Abnormal sexual function
- Allergic dermatitis
- Alopecia
- Angioedema
- Body fluid retention
- Bullous dermatitis
- Cardiac arrhythmia
- Chest pain
- Dizziness
- Eczema
- Edema
- Folliculitis
- Head sensation disturbance
- Headache disorder
- Hypotension
- Leukopenia
- Neuralgia
- Pericardial effusion
- Pericardial tamponade
- Pruritus of skin
- Pulmonary hypertension
- Reduced visual acuity
- Stevens-johnson syndrome
- Tachycardia
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Visual changes
Less Severe
- Mastalgia
- Nausea
- Skin rash
- Vasodilation of blood vessels
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Minoxidil (Oral)
Limited safety data available for infants.
Safety and efficacy not established in children less than 18 years.
- 1 Day – 364 Days
- Limited safety data available for infants.
- 1 Day – 18 Years
- Limited safety data available for infants.
Minoxidil(Top)
Limited safety data available for infants.
Safety and efficacy not established in children less than 18 years.
- 1 Day – 364 Days
- Safety and efficacy not established in children less than 18 years.
- 1 Day – 18 Years
- Safety and efficacy not established in children less than 18 years.
Minoxidil (oral)
- Severity Level:
C
- Additional Notes: Insuff human data avail; animal data suggests fetal reabsorption at 5x mrhd
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Minoxidil
Insufficient data available; systemic effects unlikely with topical use
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Insufficient data available; systemic effects unlikely with topical use |
No Known Risk
Minoxidil (topical)
Small amount absorbed systemically, unlikely to cause adverse effects
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Small amount absorbed systemically, unlikely to cause adverse effects |
Contraindicated
None
Precaution Exists
Minoxidil
Renal-Risk of fluid retention, CHF, pericardial effusion increased with impaired renal function.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- Minoxidil may cause serious heart problems or worsen chest pain (angina). Therefore, this medication is only used when other treatments have not worked well or cannot be taken. Your doctor should direct you to also take other medications to reduce the side effects of minoxidil.<br /><br />These medications include a "water pill" (diuretic) to prevent the body from holding on to too much water and salt and a heart medication (such as a beta blocker including propranolol) to prevent the heart from working too hard or beating too fast. Your doctor will follow you closely while you are taking this medication. Keep all regular medical and laboratory appointments.
| Alopecia | |
| A51.32 | Syphilitic alopecia |
| L63 | Alopecia areata |
| L63.0 | Alopecia (capitis) totalis |
| L63.1 | Alopecia universalis |
| L63.2 | Ophiasis |
| L63.8 | Other alopecia areata |
| L63.9 | Alopecia areata, unspecified |
| L64 | Androgenic alopecia |
| L64.0 | Drug-induced androgenic alopecia |
| L64.8 | Other androgenic alopecia |
| L64.9 | Androgenic alopecia, unspecified |
| L65 | Other nonscarring hair loss |
| L65.0 | Telogen effluvium |
| L65.2 | Alopecia mucinosa |
| L65.8 | Other specified nonscarring hair loss |
| L65.9 | Nonscarring hair loss, unspecified |
| L66 | Cicatricial alopecia [scarring hair loss] |
| L66.0 | Pseudopelade |
| L66.1 | Lichen planopilaris |
| L66.2 | Folliculitis decalvans |
| L66.3 | Perifolliculitis capitis abscedens |
| L66.4 | Folliculitis ulerythematosa reticulata |
| L66.8 | Other cicatricial alopecia |
| L66.9 | Cicatricial alopecia, unspecified |
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| A51.32 | Syphilitic alopecia |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| L63 | Alopecia areata |
| L63.0 | Alopecia (capitis) totalis |
| L63.1 | Alopecia universalis |
| L63.2 | Ophiasis |
| L63.8 | Other alopecia areata |
| L63.9 | Alopecia areata, unspecified |
| L64 | Androgenic alopecia |
| L64.0 | Drug-induced androgenic alopecia |
| L64.8 | Other androgenic alopecia |
| L64.9 | Androgenic alopecia, unspecified |
| L65 | Other nonscarring hair loss |
| L65.0 | Telogen effluvium |
| L65.2 | Alopecia mucinosa |
| L65.8 | Other specified nonscarring hair loss |
| L65.9 | Nonscarring hair loss, unspecified |
| L66 | Cicatricial alopecia [scarring hair loss] |
| L66.0 | Pseudopelade |
| L66.1 | Lichen planopilaris |
| L66.2 | Folliculitis decalvans |
| L66.3 | Perifolliculitis capitis abscedens |
| L66.4 | Folliculitis ulerythematosa reticulata |
| L66.8 | Other cicatricial alopecia |
| L66.9 | Cicatricial alopecia, unspecified |
Formulary Reference Tool