DIPENTUM (OLSALAZINE SODIUM)
- Ulcerative colitis remission
250 mg capsule
- 2 capsules (500 mg) by oral route 2 times per day
Ulcerative colitis remission
- 2 capsules (500 mg) by oral route 2 times per day
- None
Contraindicated
- Coumadin
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- Jantoven
- Methotrexate (anti-rheumatic)
- methotrexate sodium
- methotrexate sodium (PF)
- Rheumatrex
- Trexall
- varicella virus vacc live (PF)
- Varivax (pf)
- warfarin
Severe
Moderate
- A-hydrocort
- A-methapred
- acetazolamide
- acetazolamide sodium
- Amaryl
- Anucort-hc
- Anusol-hc
- Aristospan Intra-articular
- Aristospan Intralesional
- Arixtra
- betamethasone acet & sod phos
- budesonide
- Celestone Soluspan
- colchicine-probenecid
- Colocort
- Cortef
- Cortenema
- Cortifoam
- cortisone
- dalteparin (porcine)
- Depacon
- Depakene
- Depakote
- Depakote Er
- Depakote Sprinkles
- Depo-medrol
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Diabeta
- Diamox Sequels
- divalproex
- Duetact
- Elmiron
- enoxaparin
- Entocort Ec
- Ez Use Joint-tunnel-trigger
- First-duke's
- First-mary's Mouthwash
- Flo-pred
- fludrocortisone
- fondaparinux
- Fragmin
- glimepiride
- glipizide
- glipizide-metformin
- Glucotrol
- Glucotrol Xl
- Glucovance
- glyburide
- glyburide micronized
- glyburide-metformin
- Glynase
- Grx Hicort 25
- Hemril-30
- heparin (porcine)
- heparin (porcine) in D5W
- heparin(porcine) in 0.45% NaCl
- heparin, porcine (PF)
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- Kenalog
- Lovenox
- Medrol
- Medrol (pak)
- methazolamide
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- Millipred
- Millipred Dp
- nateglinide
- Neptazane
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Orapred
- Orapred Odt
- Pediapred
- pentosan polysulfate sodium
- Physicians Ez Use M-pred
- pioglitazone-glimepiride
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- probenecid
- Proctocort
- Rayos
- Rectacort-hc
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Starlix
- Stavzor
- tolazamide
- tolbutamide
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- Uceris
- valproate sodium
- valproic acid
- valproic acid (as sodium salt)
- Veripred 20
- None
Contraindicated
- None
Severe
Moderate
- Allergic rhinitis
- Asthma
- Diarrhea
- Disease of liver
- Kidney disease with reduction in GFR
DIPENTUM (OLSALAZINE SODIUM)
- Ulcerative colitis remission
- None
- Diarrhea
- Gastrointestinal irritation
More Frequent
Severe
Less Severe
- Skin rash
- Stomatitis
- Abdominal distension
- Arthralgias
- Depression
- Dizziness
- Drowsy
- Headache disorder
- Heartburn
- Insomnia
- Nausea
- Pruritus of skin
- Upper abdominal pain
- Upper respiratory infection
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute pancreatitis
- Anemia
- Angioedema
- Aplastic anemia
- Blurred vision
- Bronchospastic pulmonary disease
- Chest pain
- Chills
- Disease of liver
- Dry eye
- Erythema nodosum
- Exacerbation of ulcerative colitis
- Hematuria
- Hemolytic anemia
- Hepatitis
- Hypertension
- Interstitial lung disease
- Interstitial nephritis
- Leukopenia
- Myocarditis
- Pancytopenia
- Pericarditis
- Peripheral edema
- Tachycardia
- Thrombocytopenic disorder
- Tinnitus
Less Severe
- Abnormal hepatic function tests
- Alopecia
- Anorexia
- Cramps
- Dysuria
- Erectile dysfunction
- Erythema
- Fever
- Flatulence
- Increased urinary frequency
- Menorrhagia
- Mood changes
- Myalgias
- Orthostatic hypotension
- Palpitations
- Paresthesia
- Peripheral neuropathy
- Tremor
- Xerostomia
Contraindicated
None
Severe Precaution
Olsalazine Sodium
Not recommended in febrile pediatric or adolescent patients.
- 1 Day – 18 Years
- Not recommended in febrile pediatric or adolescent patients.
Management or Monitoring Precaution
None
Olsalazine
- Severity Level:
C
- Additional Notes:
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Olsalazine
Diarrhea has occurred in one infant, observe closely for stool changes.
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Drug shown to have adverse effect | Diarrhea has occurred in one infant, observe closely for stool changes. |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Olsalazine
General-Converted to mesalamine. Hematological-Greater risk of blood dyscrasias (e.g. agranulocytosis, neutropenia and pancytopenia) compared to younger patients. Consider monitoring blood counts during treatment. Renal-Monitor renal function for toxicity.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | Y | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
Ulcerative colitis remission | |
K51.00 | Ulcerative (chronic) pancolitis without complications |
K51.20 | Ulcerative (chronic) proctitis without complications |
K51.30 | Ulcerative (chronic) rectosigmoiditis without complications |
K51.40 | Inflammatory polyps of colon without complications |
K51.50 | Left sided colitis without complications |
K51.80 | Other ulcerative colitis without complications |
K51.90 | Ulcerative colitis, unspecified, without complications |
0-9 | A-Z |
---|---|
K51.00 | Ulcerative (chronic) pancolitis without complications |
K51.20 | Ulcerative (chronic) proctitis without complications |
K51.30 | Ulcerative (chronic) rectosigmoiditis without complications |
K51.40 | Inflammatory polyps of colon without complications |
K51.50 | Left sided colitis without complications |
K51.80 | Other ulcerative colitis without complications |
K51.90 | Ulcerative colitis, unspecified, without complications |