TYLENOL COLD MAX (DEXTROMETHORPHAN HBR/PHENYLEPHRINE/ACETAMINOPHEN/DOXYLAMINE)

Contraindicated



• Azilect
• Eldepryl
• isocarboxazid
• linezolid
• Marplan
• Matulane
• methylene blue (antidote)
• Nardil
• Parnate
• phenelzine
• procarbazine
• rasagiline
• selegiline HCl
• tranylcypromine
• Zelapar
• Zyvox

Severe



• bromocriptine
• cabergoline
• Cafergot
• Compound 347
• Cycloset
• D.h.e.45
• dihydroergotamine
• enflurane
• ergoloid
• Ergomar
• ergotamine tartrate
• ergotamine-caffeine
• Forane
• isoflurane
• methylergonovine
• Migergot
• Migranal
• Parlodel
• sevoflurane
• Sojourn
• Terrell
• Ultane

Contraindicated



• Acetaminophen overdose
• Acute hepatic failure
• Acute hepatitis C
• Acute myocardial infarction
• Arterial thrombosis
• Severe uncontrolled hypertension
• Ventricular tachycardia

Severe



• Acute hepatitis
• Acute pancreatitis
• Angle-closure glaucoma
• Benign prostatic hyperplasia
• Bladder outflow obstruction
• Bradycardia
• Chronic idiopathic constipation
• Coronary artery disease
• Disease of liver
• Hypertension
• Hyperthyroidism
• Incomplete AV heart block
• Protein-calorie malnutrition
• Severe arteriosclerotic vascular disease
• Severe renal impairment
• Shock
• Stenosing peptic ulcer
• Systemic mastocytosis
• Urinary retention

Contraindicated

Dextromethorphan (OTC)

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 1 Day – 2 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.

Doxylamine

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.
• 1 Day – 2 Years
• 1 CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Phenylephrine (Oral,Rectal)

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Risk of CNS excitation. Do not use age <6 years without clinician consult.

• 1 Day – 6 Years
• 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
• 1 Day – 2 Years
• 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.

Severe Precaution

Doxylamine

CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.

• 2 Years – 6 Years
• CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.

Management or Monitoring Precaution

Acetaminophen (oral,rectal)

Use weight based dosing in children less than 12 years.

• 1 Day – 12 Years
• Use weight based dosing in children less than 12 years.