LOXAPINE (LOXAPINE SUCCINATE)

Moderate

• Alagesic Lq

• amobarbital

• Amytal

• Anaspaz

• Aplenzin

• Ascomp With Codeine

• Atropen

• atropine

• belladonna alkaloids-opium

• Belladonna-opium

• Belladonna-phenobarbital

• Bentyl

• benztropine

• Bupap

• Buproban

• bupropion HBr

• bupropion HCl

• butabarbital

• Butalbital Compound W/codeine

• Butalbital Compound-codeine

• butalbital-acetaminop-caf-cod

• butalbital-acetaminophen

• butalbital-acetaminophen-caff

• butalbital-aspirin-caffeine

• Butisol

• Cantil

• Capacet

• chlordiazepoxide-clidinium

• chlorphen-pseudoeph-bellad alk

• codeine-butalbital-ASA-caff

• Cogentin

• Cuvposa

• dicyclomine

• diphenoxylate-atropine

• Ditropan Xl

• Donnatal

• Duodote

• Ed-spaz

• edrophonium Cl-atropine

• Enlon-plus

• Esgic

• Fioricet

• Fioricet With Codeine

• Fiorinal

• Fiorinal-codeine #3

• flavoxate

• Forfivo Xl

• Gelnique

• Glycate

• glycopyrrolate

• Hydrocodone Compound

• hydrocodone-homatropine

• Hydromet

• Hyophen

• hyoscyamine sulfate

• Hyosyne

• Levbid

• Levsin

• Levsin/sl

• Librax (with Clidinium)

• Lomotil

• Luminal

• Margesic

• Marten-tab

• mepenzolate bromide

• methen-hyos-me blue-ba-salicyl

• methen-hyosc-m.blue-sal-naphos

• methen-sod phos-meth blue-hyos

• methscopolamine

• mth-me blue-sod phos-phsal-hyo

• Mysoline

• Nembutal Sodium

• Nulev

• Oscimin

• Oscimin Sl

• Oscimin Sr

• oxybutynin

• oxybutynin chloride

• Oxytrol

• Oxytrol For Women

• Pamine

• Pamine Forte

• pentobarbital sodium

• phenobarb-hyoscy-atropine-scop

• phenobarbital

• phenobarbital sodium

• Phosphasal

• pralidoxime-atropine

• primidone

• propantheline

• Prosed/ds (atropine Free)

• Respa-ar

• Robinul

• Robinul Forte

• scopolamine base

• scopolamine HBr

• secobarbital sodium

• Seconal Sodium

• Symax Duotab

• Symax Fastabs

• Symax-sl

• Symax-sr

• Tencon

• Transderm-scop

• trihexyphenidyl

• Tussigon

• Ur N-c

• Urelle

• Uretron D-s

• Uribel

• Urimar-t

• Urin Ds

• Urogesic-blue

• Uryl

• Ustell

• Uta

• Wellbutrin

• Wellbutrin Sr

• Wellbutrin Xl

• Zebutal

• Zyban

Moderate

• Glaucoma

• Hyperprolactinemia

• Pigmentary retinopathy

• Seizure disorder

• Severe cardiovascular disease

• Urinary retention

Loxapine

• Severity Level:

  C

• Additional Notes: Neonate complications (resp, gi, cns) with exposure in 3rd trimester

Contraindicated

None

General	Excretion Potential	Effect on Infant	Notes
			None

Precaution Exists

Loxapine

Insufficient human data; manufacturer does not recommend

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Unknown	Not known; no or inclusive data	Insufficient human data; manufacturer does not recommend

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Loxapine

Neuro/Psych-Higher risk of tardive dyskinesia in the elderly. Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Increased risk of death in senile dementia. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	Y	Y	N	N

BEERS: Y     HEDIS: Y     STOPP: Y

No Known Risk

None

0-9	A-Z
F20	Schizophrenia
F20.0	Paranoid schizophrenia
F20.1	Disorganized schizophrenia
F20.2	Catatonic schizophrenia
F20.3	Undifferentiated schizophrenia
F20.5	Residual schizophrenia
F20.8	Other schizophrenia
F20.81	Schizophreniform disorder
F20.89	Other schizophrenia
F20.9	Schizophrenia, unspecified