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METAXALONE (metaxalone)
- Muscle spasm
800 mg tablet
- 1 tablet (800 mg) by oral route 3 times per day as needed
400 mg tablet
- 2 tablets (800 mg) by oral route 3 times per day as needed
800 mg tablet
- 1 tablet (800 mg) by oral route 3 times per day as needed
800 mg tablet
- 1 tablet (800 mg) by oral route 3 times per day as needed
Muscle spasm
- 1 tablet (800 mg) by oral route 3-4 times daily as needed
- 1 tablet (800 mg) by oral route 3 times per day as needed
- 1 tablet (800 mg) by oral route 4 times per day as needed
- 2 tablets (800 mg) by oral route 3 times per day as needed
- 2 tablets (800 mg) by oral route 4 times per day as needed
- 2 tablets (800 mg) by oral route 3-4 times daily as needed
- None
Contraindicated
- sodium oxybate
- Xyrem
Severe
Moderate
- None
- Acute hepatic failure
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Chronic kidney disease stage 5 (failure) GFr<15 ml/min
- Hemolytic anemia
- Severe hepatic disease
Contraindicated
- None
Severe
Moderate
- None
METAXALONE (metaxalone)
- Muscle spasm
- None
- Abdominal pain with cramps
- Dizziness
- Drowsy
- Gastrointestinal irritation
- Headache disorder
- Nausea
- Nervousness
- Vomiting
More Frequent
Severe
Less Severe
- Syncope
- Insomnia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Allergic dermatitis
- Anaphylaxis
- Drug-induced hepatitis
- Dyspnea
- Hemolytic anemia
- Jaundice
- Leukopenia
- Pruritus of skin
- Serotonin syndrome
- Skin rash
- Urticaria
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Metaxalone
Safety and efficacy not established for pediatric patients less than 12 years.
- 1 Day – 12 Years
- Safety and efficacy not established for pediatric patients less than 12 years.
Metaxalone
- Severity Level:
2
- Additional Notes: Insufficient human data available
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Metaxalone
Low molecular weight,possible excretion;Monitor infant for sedation
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Low molecular weight,possible excretion;Monitor infant for sedation |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Muscle spasm | |
| M62.83 | Muscle spasm |
| M62.830 | Muscle spasm of back |
| M62.831 | Muscle spasm of calf |
| M62.838 | Other muscle spasm |
| R25.2 | Cramp and spasm |
| 0-9 | A-Z |
|---|---|
| M62.83 | Muscle spasm |
| M62.830 | Muscle spasm of back |
| M62.831 | Muscle spasm of calf |
| M62.838 | Other muscle spasm |
| R25.2 | Cramp and spasm |
Formulary Reference Tool