MEKINIST (TRAMETINIB DIMETHYL SULFOXIDE)

0.5 mg tablet

• 2 tablets (1 mg) by oral route once daily at least 1 hour beforeor 2 hours after meals

2 mg tablet

• 1 tablet (2 mg) by oral route once daily at least 1 hour before or 2 hours after meals

Anaplastic thyroid carcinoma with BRAF v600E mutation

• 2 tablets (1 mg) by oral route once daily at least 1 hour beforeor 2 hours after meals

• 1 tablet (2 mg) by oral route once daily at least 1 hour before or 2 hours after meals

Malignant melanoma with BRAF v600E mutation

• 2 tablets (1 mg) by oral route once daily at least 1 hour beforeor 2 hours after meals

• 1 tablet (2 mg) by oral route once daily at least 1 hour before or 2 hours after meals

Malignant melanoma with BRAF v600K mutation

• 2 tablets (1 mg) by oral route once daily at least 1 hour beforeor 2 hours after meals

• 1 tablet (2 mg) by oral route once daily at least 1 hour before or 2 hours after meals

Non-small cell lung cancer with BRAF v600E mutation

• 2 tablets (1 mg) by oral route once daily at least 1 hour beforeor 2 hours after meals

• 1 tablet (2 mg) by oral route once daily at least 1 hour before or 2 hours after meals