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METHADONE HCL (methadone HCl)
- Chronic pain
- Opioid dependence
- Severe pain
- Opioid withdrawal symptoms
- Methadose Soluble Tablet
- Methadose Oral Concentrate
- Methadone Tablet
- Methadone Soluble Tablet
- Methadone Oral Solution
- Methadone Oral Concentrate
- Methadone Intensol Oral Concentrate
- Dolophine Tablet
- Diskets Soluble Tablet
- By Indication
40 mg soluble tablet
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route once daily
10 mg/mL oral concentrate
- 1 milliliter (10 mg) by oral route every 8 hours
10 mg tablet
- 1 tablet (10 mg) by oral route every 8 hours
5 mg tablet
- 1 tablet (5 mg) by oral route every 8 hours
methadone 10 mg tablet
- 1 tablet (10 mg) by oral route every 8 hours
methadone 5 mg tablet
- 1 tablet (5 mg) by oral route every 8 hours
methadone 40 mg soluble tablet
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route once daily
methadone 10 mg/5 mL oral solution
- 1.25 milliliters (2.5 mg) by oral route every 12 hours
methadone 5 mg/5 mL oral solution
- 2.5 milliliters (2.5 mg) by oral route every 8 hours
methadone 10 mg/mL oral concentrate
- 1 milliliter (10 mg) by oral route every 8 hours
10 mg/mL oral concentrate
- 1 milliliter (10 mg) by oral route every 8 hours
Dolophine 10 mg tablet
- 1 tablet (10 mg) by oral route every 8 hours
Dolophine 5 mg tablet
- 1 tablet (5 mg) by oral route every 8 hours
40 mg soluble tablet
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route once daily
Chronic pain
- 1 tablet (5 mg) by oral route every 8 hours
- 1 tablet (5 mg) by oral route every 12 hours
- 2 tablets (10 mg) by oral route every 8 hours
- 2 tablets (10 mg) by oral route every 12 hours
- 1 tablet (10 mg) by oral route every 12 hours
- 1 tablet (10 mg) by oral route every 8 hours
- 1 milliliter (10 mg) by oral route every 8 hours
- 1 milliliter (10 mg) by oral route every 12 hours
- 10 milliliters (10 mg) by oral route every 12 hours
- 10 milliliters (10 mg) by oral route every 8 hours
- 5 milliliters (10 mg) by oral route every 8 hours
- 5 milliliters (10 mg) by oral route every 12 hours
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route every 12 hours
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route every 8 hours
- 2.5 milliliters (2.5 mg) by oral route every 8 hours
- 2.5 milliliters (2.5 mg) by oral route every 12 hours
- 1.25 milliliters (2.5 mg) by oral route every 12 hours
- 1.25 milliliters (2.5 mg) by oral route every 8 hours
Opioid dependence
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route once daily
Severe pain
- 1 tablet (5 mg) by oral route every 8 hours
- 1 tablet (5 mg) by oral route every 12 hours
- 2 tablets (10 mg) by oral route every 8 hours
- 2 tablets (10 mg) by oral route every 12 hours
- 1 tablet (10 mg) by oral route every 12 hours
- 1 tablet (10 mg) by oral route every 8 hours
- 1 milliliter (10 mg) by oral route every 8 hours
- 1 milliliter (10 mg) by oral route every 12 hours
- 10 milliliters (10 mg) by oral route every 12 hours
- 10 milliliters (10 mg) by oral route every 8 hours
- 5 milliliters (10 mg) by oral route every 8 hours
- 5 milliliters (10 mg) by oral route every 12 hours
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route every 12 hours
- 1 tablet (40 mg) dissolved in at least 6 ounces of cool water orjuice by oral route every 8 hours
- 2.5 milliliters (2.5 mg) by oral route every 8 hours
- 2.5 milliliters (2.5 mg) by oral route every 12 hours
- 1.25 milliliters (2.5 mg) by oral route every 12 hours
- 1.25 milliliters (2.5 mg) by oral route every 8 hours
- amiodarone
- amiodarone in dextrose,iso-osm
- artemether-lumefantrine
- Coartem
- Cordarone
- Depade
- didanosine
- disopyramide
- dronedarone
- droperidol
- itraconazole
- ketoconazole
- Multaq
- naltrexone
- naltrexone microspheres
- Nexterone
- Norpace
- Norpace Cr
- Onmel
- Orap
- Pacerone
- pimozide
- Revia
- Sporanox
- Sporanox Pulsepak
- Videx 2 Gram Pediatric
- Videx 4 Gram Pediatric
- Vivitrol
Contraindicated
- Betapace
- Betapace Af
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- butorphanol tartrate
- Butrans
- Caprelsa
- Corvert
- Diflucan
- dofetilide
- Fareston
- flecainide
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- Geodon
- ibutilide fumarate
- Invega
- Invega Sustenna
- Invirase
- Kaletra
- lopinavir-ritonavir
- nalbuphine
- nilotinib
- paliperidone
- paliperidone palmitate
- procainamide
- propafenone
- Qualaquin
- quinine sulfate
- Rythmol
- saquinavir mesylate
- sodium oxybate
- Sorine
- sotalol
- Sotalol Af
- Suboxone
- Tasigna
- tetrabenazine
- thioridazine
- Tikosyn
- toremifene
- vandetanib
- Vfend
- Vfend Iv
- voriconazole
- Xenazine
- Xyrem
- ziprasidone HCl
- ziprasidone mesylate
- Zubsolv
Severe
Moderate
- abacavir-lamivudine-zidovudine
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Advair Diskus
- Advair Hfa
- alfuzosin
- amantadine HCl
- Anzemet
- Apokyn
- apomorphine
- arformoterol
- arsenic trioxide
- Astagraf Xl
- Atripla
- Avelox
- Avelox Abc Pack
- Avelox In Nacl (iso-osmotic)
- azithromycin
- Brovana
- budesonide-formoterol
- Cardene Iv
- Cardene Iv In Dextrose
- Cardene Iv In Sodium Chloride
- Cardene Sr
- chloroquine phosphate
- chlorpromazine
- cimetidine
- clozapine
- Clozaril
- Combivir
- Complera
- dasatinib
- dolasetron
- Dulera
- Edurant
- efavirenz
- efavirenz-emtricitabin-tenofov
- Effexor Xr
- emtricitab-rilpivirine-tenofov
- Eovist
- Fanatrex
- Fazaclo
- felbamate
- Felbatol
- fingolimod
- fluticasone-salmeterol
- fluvoxamine
- Foradil Aerolizer
- formoterol fumarate
- foscarnet
- Foscavir
- gabapentin
- gabapentin enacarbil
- gadoxetate
- Gilenya
- Gralise
- Gralise 30-day Starter Pack
- granisetron
- granisetron (PF)
- Granisol
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- Heartburn Relief
- Hecoria
- Horizant
- Incivek
- indapamide
- isoniazid-rifamp-pyrazinamide
- isradipine
- lamivudine-zidovudine
- lapatinib
- Levaquin
- Levaquin In 5 % Dextrose
- Levitra
- levofloxacin
- levofloxacin in D5W
- lithium carbonate
- lithium citrate
- Lithobid
- Luvox Cr
- moexipril
- moexipril-hydrochlorothiazide
- mometasone-formoterol
- moxifloxacin
- moxifloxacin in NaCl (iso-osm)
- Nebupent
- nelfinavir
- Neurontin
- nevirapine
- nicardipine
- nicardipine in dextrose,iso-os
- nicardipine in NaCl (iso-os)
- norfloxacin
- Noroxin
- Norvir
- Norvir Soft Gelatin
- Noxafil
- octreotide acetate
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- pasireotide
- pazopanib
- Pentam
- pentamidine
- Perforomist
- posaconazole
- Prograf
- quetiapine
- Retrovir
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- rilpivirine
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- ritonavir
- salmeterol
- Sancuso
- Sandostatin
- Sandostatin Lar Depot
- Serevent Diskus
- Seroquel
- Seroquel Xr
- Signifor
- Soltamox
- Sprycel
- stavudine
- sunitinib
- Sustiva
- Sutent
- Symbicort
- tacrolimus
- Tagamet Hb
- tamoxifen
- telaprevir
- tizanidine
- Trisenox
- Trizivir
- Tykerb
- Uniretic
- Univasc
- Uroxatral
- vardenafil
- venlafaxine
- Versacloz
- Videx Ec
- Viracept
- Viramune
- Viramune Xr
- Votrient
- Zanaflex
- Zerit
- zidovudine
- Zithromax
- Zithromax Tri-pak
- Zithromax Z-pak
- Zmax
- Zofran
- Zofran Odt
- Zuplenz
- Acute asthma attack
- Coma
- Congenital long QT syndrome
- Gastrointestinal obstruction
- Torsades de pointes
Contraindicated
- Acute pancreatitis
- Alcohol intoxication
- Alcoholism
- Drug abuse
- Hypokalemia
- Hypomagnesemia
- Intracranial hypertension
- Kidney disease with likely reduction in GFR
- Prolonged QT interval
- Respiratory depression
Severe
Moderate
- Adrenal cortical insufficiency
- Biliary tract disorder
- Cachexia
- Chronic obstructive pulmonary disease
- Constipation
- Cor pulmonale
- Debilitation
- Disease of liver
- Hypotension
- Left ventricular hypertrophy
- Seizure disorder
- Urinary retention
METHADONE HCL (methadone HCl)
- Chronic pain
- Opioid dependence
- Severe pain
- Opioid withdrawal symptoms
- Hypotension
- Constipation
- Dizziness
- Drowsy
- General weakness
- Nausea
- Syncope
- Vomiting
More Frequent
Severe
Less Severe
- Acute confusion
- Bradycardia
- Dyspnea
- Respiratory depression
- Tachycardia
- Abdominal pain with cramps
- Anorexia
- Biliary spasm
- False sense of well-being
- Headache disorder
- Hyperhidrosis
- Insomnia
- Nervousness
- Oliguria
- Orthostatic hypotension
- Ureteral spasm
- Visual changes
- Xerostomia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute respiratory insufficiency
- Adrenal cortical insufficiency
- Anaphylaxis
- Androgen deficiency
- Cardiac arrest
- Cardiac arrhythmia
- Hallucinations
- Heart failure
- Hyperprolactinemia
- Hypokalemia
- Hypomagnesemia
- Increased cerebrospinal fluid pressure
- Prolonged QT interval
- Pruritus of skin
- Pulmonary edema
- Rhabdomyolysis
- Seizure disorder
- Serotonin syndrome
- Shock
- Skin rash
- Torsades de pointes
- Urticaria
- Ventricular fibrillation
Less Severe
- Agitation
- Amenorrhea
- Asthenozoospermia
- Edema
- Erectile dysfunction
- Flushing
- Glossitis
- Infertility
- Libido changes
- Male hypogonadism
- Oligospermia
- Palpitations
- Phlebitis after infusion
- Urinary hesitancy
- Urinary retention
- Weight gain
Contraindicated
None
Severe Precaution
Narcotic Analgesics, Systemic
Potential increased sensitivity to effects, adverse CNS effects and respiratory depression.
- 1 Day – 2 Years
- Potential increased sensitivity to effects, adverse CNS effects and respiratory depression.
Management or Monitoring Precaution
None
Methadone
- Severity Level:
2
- Additional Notes: Neonatal withdrawal/resp.depress. w/chronic or high dose
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Methadone
Monitor infant for respiratory depression, drowsiness, withdrawal symptoms
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Drug shown to have adverse effect | Monitor infant for respiratory depression, drowsiness, withdrawal symptoms |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Methadone
Pulmonary-DO NOT use in opioid intolerance. Increased risk of fatal respiratory depression due to altered pharmacokinetics. Monitor closely at initiation and dose titration and when giving with other drugs that cause respiratory depression. Consider naloxone Rx. Renal-Start with low dose for renal impairment. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Cardiovascular-QT prolongation risk; syncope risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | Y | Y | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- Methadone has a risk for abuse and addiction, which can lead to overdose and death. Methadone may also cause severe, possibly fatal, breathing problems and heartbeat problems. To lower your risk, your doctor should have you take the smallest dose of methadone that works, and take it for the shortest possible time.<br /><br />Do not increase your dose or take this medication more often than directed. See also How to Use section for more information about addiction. The risk for severe breathing problems or heartbeat problems is higher when you start this medication, when you are switching from another opioid to methadone, after a dose increase, or if you take the wrong dose/strength.<br /><br />Breathing problems from methadone may not happen right away after taking a dose. Most heartbeat problems have happened in people using large doses of methadone for pain relief, but this problem can also occur in people taking smaller doses to treat opioid addiction. Taking this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause very serious side effects, including death.<br /><br />Also, other medications can affect the removal of methadone from your body, which may affect how methadone works. Be sure you know how to take methadone and what other drugs you should avoid taking with it. See also Drug Interactions section.<br /><br />Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up, fast/irregular heartbeat, fainting. Keep this medicine in a safe place to prevent theft, misuse, or abuse. If someone accidentally swallows this drug, get medical help right away.<br /><br /> Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits. Pregnancy may affect the amount of this drug in your body, so tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed.<br /><br />It may slightly increase the risk of birth defects if used during the first two months of pregnancy. Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby. To lessen the risk, take the smallest effective dose for the shortest possible time.<br /><br /> Babies born to mothers who use this drug for a long time may develop severe (possibly fatal) withdrawal symptoms. Tell the doctor right away if you notice any symptoms in your newborn baby such as crying that doesn't stop, slow/shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight.
| Chronic pain | |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.21 | Chronic pain due to trauma |
| G89.22 | Chronic post-thoracotomy pain |
| G89.28 | Other chronic postprocedural pain |
| G89.29 | Other chronic pain |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| Opioid dependence | |
| F11.2 | Opioid dependence |
| F11.20 | Opioid dependence, uncomplicated |
| F11.21 | Opioid dependence, in remission |
| F11.22 | Opioid dependence with intoxication |
| F11.220 | Opioid dependence with intoxication, uncomplicated |
| F11.221 | Opioid dependence with intoxication delirium |
| F11.222 | Opioid dependence with intoxication with perceptual disturbance |
| F11.229 | Opioid dependence with intoxication, unspecified |
| F11.23 | Opioid dependence with withdrawal |
| F11.24 | Opioid dependence with opioid-induced mood disorder |
| F11.25 | Opioid dependence with opioid-induced psychotic disorder |
| F11.250 | Opioid dependence with opioid-induced psychotic disorder with delusions |
| F11.251 | Opioid dependence with opioid-induced psychotic disorder with hallucinations |
| F11.259 | Opioid dependence with opioid-induced psychotic disorder, unspecified |
| F11.28 | Opioid dependence with other opioid-induced disorder |
| F11.281 | Opioid dependence with opioid-induced sexual dysfunction |
| F11.282 | Opioid dependence with opioid-induced sleep disorder |
| F11.288 | Opioid dependence with other opioid-induced disorder |
| F11.29 | Opioid dependence with unspecified opioid-induced disorder |
| Opioid withdrawal symptoms | |
| F11.23 | Opioid dependence with withdrawal |
| F11.93 | Opioid use, unspecified with withdrawal |
| Severe pain | |
| G89 | Pain, not elsewhere classified |
| G89.1 | Acute pain, not elsewhere classified |
| G89.11 | Acute pain due to trauma |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.21 | Chronic pain due to trauma |
| G89.22 | Chronic post-thoracotomy pain |
| G89.28 | Other chronic postprocedural pain |
| G89.29 | Other chronic pain |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| M25.5 | Pain in joint |
| M25.50 | Pain in unspecified joint |
| M25.51 | Pain in shoulder |
| M25.511 | Pain in right shoulder |
| M25.512 | Pain in left shoulder |
| M25.519 | Pain in unspecified shoulder |
| M25.52 | Pain in elbow |
| M25.521 | Pain in right elbow |
| M25.522 | Pain in left elbow |
| M25.529 | Pain in unspecified elbow |
| M25.53 | Pain in wrist |
| M25.531 | Pain in right wrist |
| M25.532 | Pain in left wrist |
| M25.539 | Pain in unspecified wrist |
| M25.54 | Pain in joints of hand |
| M25.541 | Pain in joints of right hand |
| M25.542 | Pain in joints of left hand |
| M25.549 | Pain in joints of unspecified hand |
| M25.55 | Pain in hip |
| M25.551 | Pain in right hip |
| M25.552 | Pain in left hip |
| M25.559 | Pain in unspecified hip |
| M25.56 | Pain in knee |
| M25.561 | Pain in right knee |
| M25.562 | Pain in left knee |
| M25.569 | Pain in unspecified knee |
| M25.57 | Pain in ankle and joints of foot |
| M25.571 | Pain in right ankle and joints of right foot |
| M25.572 | Pain in left ankle and joints of left foot |
| M25.579 | Pain in unspecified ankle and joints of unspecified foot |
| M26.62 | Arthralgia of temporomandibular joint |
| M54.5 | Low back pain |
| M54.6 | Pain in thoracic spine |
| M79.6 | Pain in limb, hand, foot, fingers and toes |
| M79.60 | Pain in limb, unspecified |
| M79.601 | Pain in right arm |
| M79.602 | Pain in left arm |
| M79.603 | Pain in arm, unspecified |
| M79.604 | Pain in right leg |
| M79.605 | Pain in left leg |
| M79.606 | Pain in leg, unspecified |
| M79.609 | Pain in unspecified limb |
| M79.62 | Pain in upper arm |
| M79.621 | Pain in right upper arm |
| M79.622 | Pain in left upper arm |
| M79.629 | Pain in unspecified upper arm |
| M79.63 | Pain in forearm |
| M79.631 | Pain in right forearm |
| M79.632 | Pain in left forearm |
| M79.639 | Pain in unspecified forearm |
| M79.64 | Pain in hand and fingers |
| M79.641 | Pain in right hand |
| M79.642 | Pain in left hand |
| M79.643 | Pain in unspecified hand |
| M79.644 | Pain in right finger(s) |
| M79.645 | Pain in left finger(s) |
| M79.646 | Pain in unspecified finger(s) |
| M79.65 | Pain in thigh |
| M79.651 | Pain in right thigh |
| M79.652 | Pain in left thigh |
| M79.659 | Pain in unspecified thigh |
| M79.66 | Pain in lower leg |
| M79.661 | Pain in right lower leg |
| M79.662 | Pain in left lower leg |
| M79.669 | Pain in unspecified lower leg |
| M79.67 | Pain in foot and toes |
| M79.671 | Pain in right foot |
| M79.672 | Pain in left foot |
| M79.673 | Pain in unspecified foot |
| M79.674 | Pain in right toe(s) |
| M79.675 | Pain in left toe(s) |
| M79.676 | Pain in unspecified toe(s) |
| R07.82 | Intercostal pain |
| R10.0 | Acute abdomen |
| R10.1 | Pain localized to upper abdomen |
| R10.10 | Upper abdominal pain, unspecified |
| R10.11 | Right upper quadrant pain |
| R10.12 | Left upper quadrant pain |
| R10.2 | Pelvic and perineal pain |
| R10.3 | Pain localized to other parts of lower abdomen |
| R10.30 | Lower abdominal pain, unspecified |
| R10.31 | Right lower quadrant pain |
| R10.32 | Left lower quadrant pain |
| R10.33 | Periumbilical pain |
| R10.8 | Other abdominal pain |
| R10.84 | Generalized abdominal pain |
| R10.9 | Unspecified abdominal pain |
| R52 | Pain, unspecified |
| R68.84 | Jaw pain |
| 0-9 | A-Z |
|---|---|
| F11.2 | Opioid dependence |
| F11.20 | Opioid dependence, uncomplicated |
| F11.21 | Opioid dependence, in remission |
| F11.22 | Opioid dependence with intoxication |
| F11.220 | Opioid dependence with intoxication, uncomplicated |
| F11.221 | Opioid dependence with intoxication delirium |
| F11.222 | Opioid dependence with intoxication with perceptual disturbance |
| F11.229 | Opioid dependence with intoxication, unspecified |
| F11.23 | Opioid dependence with withdrawal |
| F11.23 | Opioid dependence with withdrawal |
| F11.24 | Opioid dependence with opioid-induced mood disorder |
| F11.25 | Opioid dependence with opioid-induced psychotic disorder |
| F11.250 | Opioid dependence with opioid-induced psychotic disorder with delusions |
| F11.251 | Opioid dependence with opioid-induced psychotic disorder with hallucinations |
| F11.259 | Opioid dependence with opioid-induced psychotic disorder, unspecified |
| F11.28 | Opioid dependence with other opioid-induced disorder |
| F11.281 | Opioid dependence with opioid-induced sexual dysfunction |
| F11.282 | Opioid dependence with opioid-induced sleep disorder |
| F11.288 | Opioid dependence with other opioid-induced disorder |
| F11.29 | Opioid dependence with unspecified opioid-induced disorder |
| F11.93 | Opioid use, unspecified with withdrawal |
| G89 | Pain, not elsewhere classified |
| G89.1 | Acute pain, not elsewhere classified |
| G89.11 | Acute pain due to trauma |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.21 | Chronic pain due to trauma |
| G89.21 | Chronic pain due to trauma |
| G89.22 | Chronic post-thoracotomy pain |
| G89.22 | Chronic post-thoracotomy pain |
| G89.28 | Other chronic postprocedural pain |
| G89.28 | Other chronic postprocedural pain |
| G89.29 | Other chronic pain |
| G89.29 | Other chronic pain |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| M25.5 | Pain in joint |
| M25.50 | Pain in unspecified joint |
| M25.51 | Pain in shoulder |
| M25.511 | Pain in right shoulder |
| M25.512 | Pain in left shoulder |
| M25.519 | Pain in unspecified shoulder |
| M25.52 | Pain in elbow |
| M25.521 | Pain in right elbow |
| M25.522 | Pain in left elbow |
| M25.529 | Pain in unspecified elbow |
| M25.53 | Pain in wrist |
| M25.531 | Pain in right wrist |
| M25.532 | Pain in left wrist |
| M25.539 | Pain in unspecified wrist |
| M25.54 | Pain in joints of hand |
| M25.541 | Pain in joints of right hand |
| M25.542 | Pain in joints of left hand |
| M25.549 | Pain in joints of unspecified hand |
| M25.55 | Pain in hip |
| M25.551 | Pain in right hip |
| M25.552 | Pain in left hip |
| M25.559 | Pain in unspecified hip |
| M25.56 | Pain in knee |
| M25.561 | Pain in right knee |
| M25.562 | Pain in left knee |
| M25.569 | Pain in unspecified knee |
| M25.57 | Pain in ankle and joints of foot |
| M25.571 | Pain in right ankle and joints of right foot |
| M25.572 | Pain in left ankle and joints of left foot |
| M25.579 | Pain in unspecified ankle and joints of unspecified foot |
| M26.62 | Arthralgia of temporomandibular joint |
| M54.5 | Low back pain |
| M54.6 | Pain in thoracic spine |
| M79.6 | Pain in limb, hand, foot, fingers and toes |
| M79.60 | Pain in limb, unspecified |
| M79.601 | Pain in right arm |
| M79.602 | Pain in left arm |
| M79.603 | Pain in arm, unspecified |
| M79.604 | Pain in right leg |
| M79.605 | Pain in left leg |
| M79.606 | Pain in leg, unspecified |
| M79.609 | Pain in unspecified limb |
| M79.62 | Pain in upper arm |
| M79.621 | Pain in right upper arm |
| M79.622 | Pain in left upper arm |
| M79.629 | Pain in unspecified upper arm |
| M79.63 | Pain in forearm |
| M79.631 | Pain in right forearm |
| M79.632 | Pain in left forearm |
| M79.639 | Pain in unspecified forearm |
| M79.64 | Pain in hand and fingers |
| M79.641 | Pain in right hand |
| M79.642 | Pain in left hand |
| M79.643 | Pain in unspecified hand |
| M79.644 | Pain in right finger(s) |
| M79.645 | Pain in left finger(s) |
| M79.646 | Pain in unspecified finger(s) |
| M79.65 | Pain in thigh |
| M79.651 | Pain in right thigh |
| M79.652 | Pain in left thigh |
| M79.659 | Pain in unspecified thigh |
| M79.66 | Pain in lower leg |
| M79.661 | Pain in right lower leg |
| M79.662 | Pain in left lower leg |
| M79.669 | Pain in unspecified lower leg |
| M79.67 | Pain in foot and toes |
| M79.671 | Pain in right foot |
| M79.672 | Pain in left foot |
| M79.673 | Pain in unspecified foot |
| M79.674 | Pain in right toe(s) |
| M79.675 | Pain in left toe(s) |
| M79.676 | Pain in unspecified toe(s) |
| R07.82 | Intercostal pain |
| R10.0 | Acute abdomen |
| R10.1 | Pain localized to upper abdomen |
| R10.10 | Upper abdominal pain, unspecified |
| R10.11 | Right upper quadrant pain |
| R10.12 | Left upper quadrant pain |
| R10.2 | Pelvic and perineal pain |
| R10.3 | Pain localized to other parts of lower abdomen |
| R10.30 | Lower abdominal pain, unspecified |
| R10.31 | Right lower quadrant pain |
| R10.32 | Left lower quadrant pain |
| R10.33 | Periumbilical pain |
| R10.8 | Other abdominal pain |
| R10.84 | Generalized abdominal pain |
| R10.9 | Unspecified abdominal pain |
| R52 | Pain, unspecified |
| R68.84 | Jaw pain |
Formulary Reference Tool