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BORTEZOMIB (BORTEZOMIB)
- Mantle cell lymphoma
- Multiple myeloma
3.5 mg intravenous solution
- Dosage information is not available
Mantle cell lymphoma
- Inject 1.3 mg/m2 by intravenous route on days 1, 4, 8 and 11 of a 21 day cycle
- Inject 1.3 mg/m2 by intravenous route on days 1, 8, 15 and 22 of a 35Day cycle
Multiple myeloma
- Inject 1.3 mg/m2 by intravenous route on days 1, 4, 8, 11, 22, 25, 29And 32 of a 42 day cycle
- Inject 1.3 mg/m2 by intravenous route on days 1, 8, 22 and 29 of a 42Day cycle
- Inject 1.3 mg/m2 by intravenous route on days 1, 4, 8 and 11 of a 21 day cycle
- Inject 1.3 mg/m2 by intravenous route on days 1, 8, 15 and 22 of a 35Day cycle
- BCG vaccine, live (PF)
- adenovirus vaccine live type-7
- adenovirus vaccine live type-4
- adenovirus vac live type-4 & 7
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- typhoid vaccine
- Tysabri
- varicella virus vacc live (PF)
- Varivax (pf)
- Vivotif Berna Vaccine
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- Conceptionxr Motility
- Conceptionxr Reproductive
- Coromega
- Corvita 150
- Corvite 150
- Corvite Free
- Cosamin Ds
- cran-vitC-D mannose-inuln-brom
- Cranberry Urinary Comfort
- Decubi Vite
- deferiprone
- Diabetes Health Pack
- Dialyvite Supreme D
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- Duet Dha Balanced
- Duet Dha Ec-om 3
- Duet Dha With Omega-3
- Ecee Plus
- Effervescent Formula
- Eldercaps
- Elite-ob
- Elite-ob 400
- enzalutamide
- Epitol
- Equetro
- Concept Ob
- Complete Natal Dha
- Cold & Flu Fighter
- coenzyme Q10-L-carni-vit C & E
- cod liver oil-ascorbic acid
- Cod Liver Oil Conc With Vit C
- Clozaril
- clozapine
- Citranatal Rx (new Formula)
- Citranatal Dha (new Formula)
- Citranatal B-calm (fe Gluc)
- Citranatal Assure
- Citranatal 90 Dha (new Formula
- Children's Sour Gummies
- Children's Multi-vit Gummies
- Children's Chewables With Iron
- Children's Chewables Extra C
- Chewable Multivit-a,b,d,e,k,zn
- Cerebyx
- Cavan-ec Sod Dha
- Carni Q-gel Forte
- Carbatrol
- carbamazepine
- calcium-mag-B complex-D3-hrb61
- cal phos-mag hydrx-C & D3-phos
- C-Zn-K.ginseng-rose hips-hrb62
- C-rutin-hesper-bioflav-butchbr
- C-nate Dha
- C-500
- C-250
- C-1000 With Rose Hips
- C-1000
- C Complex
- C 500 Timed Released
- C 1000-bioflavonoids-rose Hips
- Brain Might-dha-co Q10
- Bioflex
- Belladonna-phenobarbital
- Bcomplex#4-vit D3-C-FA-zinc ox
- Balanced B Complex-vit C
- Bal-care Dha Essential
- Bal-care Dha
- Bacmin
- B3-B6-C-FA-coppr-Mg-Zn-alip ac
- B cplx-C-St.Johnwrt-K.&S.ginsg
- B complex & C no.20-folic acid
- Atabex Ec
- ascorbic acid-mv, min cmb#18
- ascorbic acid-multivit-min
- ascorbic acid-collagen
- ascorbic acid-bioflavonoids
- ascorbic acid-ascorbate ca
- Ascorbic Acid With Rose Hips
- ascorbic acid
- Aquadeks Pediatric
- antiox#13-min-FA-lutein-zeaxan
- antiox#12-om3-dha-epa-lut-zean
- antiox#10-om3-dha-epa-lut-zeax
- Airborne (with Lysine Acetate)
- Airborne (with Folic Acid)
- Airborne (lysine Hcl)
- Airborne (ascorbate Sodium)
- Active Ob
- Acerola C-500
- Acerola C
- Abatron Af
- AA-prot-arginine-C-zinc-copper
- Escavite
- Escavite Lq
- Essence C
- Ester-c With Bioflavonoids
- Eye Health Formula
- Fatigue Relief Complex
- Fazaclo
- Fe 90 Plus
- Fe C
- Fe C Plus
- Feriva
- Ferivafa
- Ferocon
- Ferotrinsic
- Ferralet 90 Dual-iron Delivery
- Ferraplus 90
- Ferrex 28
- Ferriprox
- Ferrogels Forte
- ferrous fum-B12-C-stomach conc
- ferrous fum-vit C-vit B12-FA
- fish oil-omega-3-vit C-vit E
- Flexgen
- Flexi Joint
- Flintstones Multi-vit Gummies
- Flintstones Plus Iron
- Flintstones Tab Chew
- Folivane-f
- Folivane-ob
- Folivane-plus
- fosphenytoin
- Fruit C
- Fruit C-100
- Fruit C-200
- Fruit C-500
- Fruitivits
- Germ Defense Pm
- Gesticare Dha
- glu-chon-MSM#1-D3-C-Mn-bos-bor
- gluc-chon-msm#1-C-mang-bos-bor
- gluc-chon-msm#1-vit C-mang-bor
- gluc-chon-MSM#2-C-D3-mang-born
- glucos-msm-C-Mn-ginger-willow
- glucos-msm-C-Mn-herb#21
- glucos-msm-collagen-C-Mn-hrb21
- Glucosam-chond-msm(with Boron)
- Glucosam-chondr-msm With Vit D
- glucosam-chondroit-C-manganese
- glucosam-chondroitin-vit C-Mn
- glucosam-msm-chondr-vit C-hyal
- glucosamine &chondroit-mv-min3
- Glucosamine 1500 Complex
- Glucosamine Chondroitin Maxstr
- Glucosamine Complex-msm
- Glucosamine-chond-msm Complex
- glucosamine-chond-msm-vit C-Mn
- glucosamine-chondroit-vit C-Mn
- Glucosamine-chondroitin 3X
- Glucosamine-chondroitin Complx
- Glucosamine-chondroitin Ds
- Glucosamine-chondroitin Max St
- Glucosamine-chondroitin-msm
- Glucosamine-msm Complex
- glucosamine-msm-magnesium-vitC
- Glucoten
- Gummy Dinos
- Healthy Eyes Supervision
- Hematogen
- Hematogen Fa
- Hematogen Forte
- I-caps
- I-vite Protect
- Icaps Areds
- Icar-c
- Icar-c Plus
- Immune Support Complex
- Inatal Advance
- Inatal Ultra
- Infuvite Pediatric
- Integra
- Integra F
- Integra Plus
- Iro-plex (iron Carbonyl)
- Iro-plex (iron Polysaccharide)
- Iron 100 Plus
- iron ag&fum-C-FA-mv cmb11-Ca
- iron fum & p-FA-vit B & C no.9
- iron fum & ps cmp-FA-vit C-B3
- iron fum & ps cmp-vit C-niacin
- iron fum-vit C-ascorbate sod
- iron fumarate-B12&IFC-vit C-FA
- iron gly&fum-C-B12-me-thfolate
- iron ps cmplx-folic acid-vit C
- iron, carb-FA-C-B6-B12-zinc
- iron, cbn & gluc-FA-B12-C-DSS
- iron-C-B12-B6-E-FA-IF-senna
- iron-FA#6-C-B12-biot-coppr-DSS
- iron-FA-B12-C-docusat sodium
- iron-FA-C-E-B12-bio-copper-DSS
- iron-folic acid-C-B12-biotin
- iron-vit C-vit B12-folic acid
- iron-vitC-B12-B6-E-FA-IF-senna
- isoniazid-rifamp-pyrazinamide
- Kids Cod Liver Oil & Vit D
- Lipotriad
- Luminal
- M.v.i. Adult
- Macular Benefits
- Marnatal-f
- Maxaron Forte
- Memory Complex
- Minus Weight Plus Energy
- Moviprep
- Msm Glucosamine Complex
- multivit, iron, min. cmb. 5-FA
- multivit, iron, min. cmb. 6-FA
- multivit, iron, min. no.7-FA
- multivit, min cmb#20-iron-FA
- multivit, min no.21-folic acid
- multivit-folic acid-zinc-vit C
- mv & min#10-FA-D3-alip acd-lut
- mv, min cmb #6-FA-lut-lyco-Q10
- mv, min cmb no.24-Fe ps cmp-FA
- mv, min cmb#16-FA-lutein-lycop
- mv, min cmb#43-lut-om3-dha-epa
- mv-K-om3-D3-Mg-C-ala-grn t-chr
- mv-min#22-lutein-omeg3-dha-epa
- mv-min-FA-C-Glu-Lys HCl-hc124
- mv-min-vit C-Glu-Lys ac-hb124
- mv-min-vit C-Glu-Lys HCl-hb124
- mv-mn-vitC-asbNa-Glu-Lys-hc124
- Mvc-fluoride
- mvi, adult no.1 with vit K
- mvi, adult no.2 without vit K
- mvi, pedi no.1 with vit K
- Mycobutin
- Mykidz Iron
- Mykidz Iron Fluoride
- Mynatal Advance
- Mysoline
- Nano Vm 1-3
- Nano Vm 4-8
- Nano Vm T/f
- Natachew (fe Bis-glycinate)
- Natalvirt 90 Dha
- Natalvirt Ca
- Natalvirt Flt
- Nephplex Rx
- Nephro-vite Rx
- Nephrocaps Qt
- Nicadan
- Novaferrum
- nut sup, glucose intolerant #1
- nut. tx for PKU with iron #2
- nut.tx, metab.dis, mv & min #4
- nut.tx, metab.dis, mv & min #6
- Ob Complete
- Ob Complete One
- Ob Complete Premier
- Ob Complete With Dha
- Obstetrix Dha
- Obtrex Dha
- Ocuvite
- Ocuvite Lutein & Zeaxanthin
- Optisource
- Osteo Bi-flex Triple Strength
- Pan-c 500
- ped multivit #17-iron fumarate
- ped mv A,C,D3 #21 w-fluoride
- ped mv A,C,D3 #38 w-fluoride
- pedi multivit #37 w-fluoride
- pedi multivit #37-fluor & iron
- pedi multivit #40-phytonadione
- pedi multivit A,C,&D3 no.21
- pedi multivit comb 9-iron-FA
- pedi multivit no.7-folic acid
- pedi multivit-iron, A, C,& D3
- pedi multivit-iron-Fl-A,C,& D3
- pedi mv A,C,D3 #21 with iron
- pedi mv#57-fluoride-iron
- pedi mvi no.12-sod fluoride
- pedi mvi no.16 with fluoride
- pedi mvi no.17 with fluoride
- pediatric multivit #14-iron-FA
- pediatric multivit #15-iron-FA
- pediatric multivit #17-iron
- pediatric multivit #18-iron-FA
- pediatric multivit #24-iron-FA
- pediatric multivit cmb #11-FA
- pediatric multivit comb #23-FA
- pediatric multivit comb no.2
- pediatric multivit comb no.20
- pediatric multivit comb#19-FA
- pediatric multivit no.22-D3-K
- pediatric multivit no.45-iron
- pediatric multivit no.46-iron
- pediatric MV #47 w-Fe&fluoride
- peg 3350-electrolytes-vit C
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- PN85-iron cb&asp g-FA-dha-fish
- PNV #28-iron fumarate-folic ac
- PNV #30-iron carb&aspg-FA-om3
- PNV 11-iron fum-folic acid-om3
- PNV cmb#95-ferrous fumarate-FA
- PNV comb #2-iron-FA-omega 3
- PNV Comb no.78-iron-folic acid
- PNV comb#19-iron-FA-omega 3
- PNV comb#48-iron-FA-omega 3
- PNV comb.no.44-iron-folic acid
- PNV comb.no43-iron,carb-FA-DSS
- PNV comb.no76-iron,carbonyl-FA
- PNV comb.no84-iron,carb-FA-dha
- PNV no.22-iron cbn&gluc-FA-DSS
- PNV no.51-iron-FA-om-3-dha-epa
- PNV no.66-iron,carbonyl-FA-dha
- PNV no12-iron-FA-DSS-om-3
- PNV no15-iron fum & ps cmp-FA
- Pnv Ob+dha
- PNV with Ca no.65-iron poly-FA
- PNV with Ca,no.60-iron-FA-dha
- PNV with Ca,no.71-iron-FA
- PNV with Ca,no.72-iron,carb-FA
- PNV with Ca,no.73-iron-FA
- PNV with Ca,no.74-iron-FA
- PNV with calcium no.72-iron-FA
- pnv with calcium#63-iron-FA-B6
- PNV#102-iron-FA-dha-lutein
- PNV#17-iron-FA-fish oil-dha-om
- PNV& Ca#8-iron ps-FA-Lmefolate
- Pnv-ferrous Fumarate-docu-fa
- Pnv-iron
- Pnv-total
- PNV100-iron EDTA&ps-FA-omega 3
- PNV103-Fe-FA-dha-epa-other om3
- PNV106-iron-FA-om3-dha-epa
- PNV107-iron-FA-om3-dha-epa
- PNV115-iron fumarate-FA-DSS
- PNV117-iron-FA-om3-dha-epa
- PNV119-iron fumarate-FA-DSS
- PNV22-iron cbn&gluc-FA-DSS-dha
- PNV38-iron cbn&gluc-FA-DSS-dha
- PNV53-iron b-g HCl-p-FA-omega3
- PNV54-iron b-g HCl-p-FA-omega3
- PNV55-iron bg hc&succ#2-FA-om3
- PNV55-iron bg HCl suc-p-FA-om3
- PNV55-iron fum & bisgly-FA
- PNV64-iron cbn&gluc-FA-DSS-dha
- PNV77-sod iron EDTA& ps-FA-om3
- PNV81-sod iron EDTA& ps-FA-om3
- PNV83-iron &iron aspart gly-FA
- PNV94-sod iron EDTA& ps-FA-om3
- Poly-vi-flor
- Poly-vi-flor With Iron
- Poly-vi-sol
- Poly-vi-sol With Iron
- Poly-vita
- Poly-vita (iron)
- Pr Natal 400
- Pr Natal 400 Ec
- Pr Natal 430
- Pr Natal 430 Ec
- Prenaissance 90 Dha
- Prenaissance Dha
- Prenaissance Promise
- Prenaplus
- Prenata
- Prenatabs Fa
- Prenatabs Rx
- Prenatal
- prenatal #115-iron-folic acid
- prenatal #48-iron cb&glu-FA-B6
- Prenatal + Dha
- Prenatal 19
- Prenatal 19 (with Docusate)
- Prenatal Ad
- Prenatal Low Iron
- Prenatal Multi + Dha
- Prenatal One
- Prenatal Plus
- Prenatal Plus (calcium Carb)
- Prenatal Plus With Iron (ca)
- prenatal vit #108-iron-FA
- prenatal vit #32-iron-FA-dha
- prenatal vit #7-iron-FA-DSS
- prenatal vit no.91-iron-FA-dha
- prenatal vit no.92-iron-FA-dha
- prenatal vit#103-iron-FA
- prenatal vit#96-ferrous fum-FA
- prenatal vit37-iron-folic acid
- Preservision Areds
- Preservision Areds 2
- Preservision Lutein
- Prevent
- primidone
- Pro-cal
- Protect Iron
- Proteinex Wc
- Protexin
- R-natal Ob
- Red Wine Complex
- Red Wine Extract
- Red Wine Extract Plus
- Relnate Dha
- Rena-vite Rx
- Req49+
- Resource Diabetishield
- resver-red-bfl-grpsd-pol-C-pom
- resver-wine-bfl-grpsd-pc-C-grp
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- Se-natal 19 (with Docusate)
- Setonet
- Setonet-ec
- Similac Prenatal
- Soothing Pureway-c
- Sourcecf Multivit With Zinc
- Span C
- St. John's wort
- Strawberry C
- Stress Formula With Iron
- Stress Formula With Iron(sulf)
- Strovite
- Strovite Forte
- Strovite One
- Strovite Plus
- Stuart Prenatal + Dha
- Super B Complex + C
- Super Energy Booster
- Supervite (ec)
- Taron-bc
- Tart Cherry
- Tegretol
- Tegretol Xr
- Theranatal
- Theranatal Complete
- Tl Icon
- Tl-fluorivite
- Tl-icare
- Tozal
- Tri-vi-flor
- Tri-vi-floro
- Tri-vi-sol With Iron
- Tri-vita
- Triadvance
- Tricare
- Tricare Prenatal Compleat
- Tricon
- Trigels-f Forte
- Trinatal Gt
- Trinate
- Triveen-duo Dha
- Trombonex
- Trust Natal Dha
- Ultra Inflamx Plus 360
- Ultra Potent-c
- Uti-stat
- V-c Forte
- Vasoflex
- Vasoflex Forte
- Vasoflex Hd
- Vena-bal Dha
- Venatal Complete Dha
- Venatal-fa
- Versacloz
- Vic-forte
- Vinacal
- Vinacal B
- Vinate Gt
- Vinate Pn Care
- Vinate Ultra
- Virt-bal Dha
- Virt-bal Dha Plus
- Virt-caps
- vit A-vit C-zinc-propolis
- vit B cmplex 3-FA-C-biot-Zn ox
- vit B cmplx & C #11-ca-dha-Q10
- vit B cmplx 3-FA-vit C-biotin
- vit B comp-C-FA-iron sulf-vitE
- vit B comp-C-FA-iron-vit E
- vit B complex & C no.13-FA-D3
- vit C,E-Zn-coppr-lutein-zeaxan
- vit c-ascorbate Ca-ascorb sod
- vit C-B6-B5-magnesium-hrb #173
- vit C-bioflav-hesp-rutin-hb196
- vit C-but.broom-hesperidn-dios
- vit C-butchers broom-hesperidn
- vit C-cherry-celery-grape
- vit C-D3-E-FA-Zn-sel-lyc-L-car
- vit C-E-FA-zinc-selenium-lycop
- vit C-hesperidin-bioflavonoids
- vit C-St. John wort-elder-hb30
- vit C-vit E-copper-ZnOx-lutein
- vit C-vit E-lutein-min-om-3
- vit C-vit E-Se-ginkgo biloba
- vit E- vit C-magnesium-zinc
- Vita-c
- Vital-d Rx
- Vitaspire
- vitC-dietary combo. no.18
- Vitron-c
- vits A,C,E-lutein-zeax-zn-copp
- Viva Dha
- Vol-care Rx
- Vol-nate
- Vol-plus
- Vol-tab Rx
- Women's Complex
- Xphe Maxamum Drink
- Xtandi
- Xydra Ef
- Zinc (with A & C) Lozenges
- Zinc Plus
- Zoo Friends
- Zoo Friends Complete
Severe
Moderate
- Diskets
- Dolophine
- Betapace Af
- Betapace
- bedaquiline
- arsenic trioxide
- Ablavar
- eribulin
- ezogabine
- gadofosveset trisodium
- Halaven
- Istodax
- methadone
- Methadone Intensol
- Methadose
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- Potiga
- romidepsin
- Sirturo
- Sorine
- sotalol
- Sotalol Af
- telavancin
- Trisenox
- Vibativ
- Zofran
- Zofran Odt
- Zuplenz
- Acute respiratory distress syndrome
- Lactating mother
- Posterior reversible encephalopathy syndrome
Contraindicated
- Chronic heart failure
- Dehydration
- Disease of liver
- Hypotension
- Ileus
- Interstitial pneumonitis
- Neutropenic disorder
- Peripheral neuropathy
- Pneumonia
- Pregnancy
- Pulmonary hypertension
- Thrombocytopenic disorder
- Thrombotic thrombocytopenic purpura
Severe
Moderate
- Diabetes mellitus
- Orthostatic hypotension
BORTEZOMIB (BORTEZOMIB)
- Mantle cell lymphoma
- Multiple myeloma
- Anemia
- Dehydration
- Dysesthesia
- Dyspnea
- Herpes zoster
- Hypokalemia
- Hypotension
- Neutropenic disorder
- Paresthesia
- Peripheral edema
- Pneumonia
- Thrombocytopenic disorder
- Upper respiratory infection
- Acute abdominal pain
- Anorexia
- Arthralgias
- Back pain
- Blurred vision
- Bone pain
- Chills
- Constipation
- Cough
- Cramps
- Diarrhea
- Dizziness
- Dysgeusia
- Dyspepsia
- Edema
- Fatigue
- Fever
- General weakness
- Headache disorder
- Insomnia
- Leukopenia
- Limb pain
- Lymphopenia
- Myalgias
- Nausea
- Neuralgia
- Peripheral neuropathy
- Pharyngitis
- Pruritus of skin
- Skin rash
- Symptoms of anxiety
- Vomiting
More Frequent
Severe
Less Severe
- Chronic heart failure
- Intestinal perforation
- Psychiatric disorder
- Herpes simplex infection
- Hyperglycemia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute hepatic failure
- Acute myocardial infarction
- Acute pancreatitis
- Acute respiratory distress syndrome
- Altered mental status
- Anaphylaxis
- Angina
- Angioedema
- Ascites
- Atelectasis
- Atrial fibrillation
- Atrial flutter
- Atrioventricular block
- Bacteremia
- Bacterial sepsis
- Bloody vomit
- Bradycardia
- Cerebrovascular accident
- Cholestasis
- Coma
- COPD exacerbation
- Diplopia
- Disseminated intravascular coagulation
- Encephalopathy
- Fecal impaction
- Gastritis
- Gastroenteritis
- Gastrointestinal obstruction
- Glomerulonephritis
- Hearing loss
- Hematuria
- Hemolytic uremic syndrome
- Hemoptysis
- Hemorrhagic cystitis
- Hemorrhagic stroke
- Hepatitis
- Herpes simplex meningitis
- Herpes zoster ophthalmicus
- Hyperbilirubinemia
- Hypercalcemia
- Hyperkalemia
- Hypernatremia
- Hypersensitivity angiitis
- Hypersensitivity drug reaction
- Hypertension
- Hyperuricemia
- Hypocalcemia
- Hyponatremia
- Hypoxia
- Ileus
- Interstitial pneumonitis
- Intracerebral hemorrhage
- Ischemic colitis
- Kidney stone
- Laryngeal edema
- Myocardial ischemia
- Optic neuropathy
- Paralysis
- Paralytic ileus
- Pericardial effusion
- Pericardial tamponade
- Pericarditis
- Peritonitis
- Pleural effusions
- Posterior reversible encephalopathy syndrome
- Postherpetic neuralgia
- Progressive multifocal leukoencephalopathy
- Prolonged QT interval
- Pulmonary hypertension
- Pulmonary infiltrates
- Pulmonary thromboembolism
- Renal failure
- Seizure disorder
- Sinus arrest
- Stevens-johnson syndrome
- Sudden visual loss
- Suicidal ideation
- Sweet's syndrome
- Thrombotic thrombocytopenic purpura
- Torsades de pointes
- Toxic epidermal necrolysis
- Transient cerebral ischemia
- Venous thrombosis
- Ventricular tachycardia
- Vision loss
- Worsening of chronic heart failure
Less Severe
- Acute confusion
- Agitation
- Ataxia
- Black tarry stools
- Blepharitis
- Conjunctivitis
- Dysarthria
- Dysphagia
- Epistaxis
- Facial edema
- Gastroesophageal reflux disease
- Ocular irritation
- Oral candidiasis
- Sinusitis
- Stomatitis
- Urinary incontinence
- Urinary retention
- Urinary tract infection
- Urticaria
- Vertigo
- Viral infection
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Bortezomib
Efficacy not established for pediatrics in relapsed pre-B acute lymphoblastic leukemia.
- 1 Day – 18 Years
- Efficacy not established for pediatrics in relapsed pre-B acute lymphoblastic leukemia.
Bortezomib
- Severity Level:
D
- Additional Notes: Based on drug pharmacology developmental toxicity is possible.
Contraindicated
Bortezomib
Potential for serious adv rxns in infant, avoid bf during & 2 months after tx
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Potential for serious adv rxns in infant, avoid bf during & 2 months after tx |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Bortezomib
General-Patients >65 years old may experience more severe toxicities. Hepatic-Dosage adjustment in hepatic insufficiency recommended.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Mantle cell lymphoma | |
| C83.1 | Mantle cell lymphoma |
| C83.10 | Mantle cell lymphoma, unspecified site |
| C83.11 | Mantle cell lymphoma, lymph nodes of head, face, and neck |
| C83.12 | Mantle cell lymphoma, intrathoracic lymph nodes |
| C83.13 | Mantle cell lymphoma, intra-abdominal lymph nodes |
| C83.14 | Mantle cell lymphoma, lymph nodes of axilla and upper limb |
| C83.15 | Mantle cell lymphoma, lymph nodes of inguinal region and lower limb |
| C83.16 | Mantle cell lymphoma, intrapelvic lymph nodes |
| C83.17 | Mantle cell lymphoma, spleen |
| C83.18 | Mantle cell lymphoma, lymph nodes of multiple sites |
| C83.19 | Mantle cell lymphoma, extranodal and solid organ sites |
| Multiple myeloma | |
| C90.0 | Multiple myeloma |
| C90.00 | Multiple myeloma not having achieved remission |
| C90.02 | Multiple myeloma in relapse |
| 0-9 | A-Z |
|---|---|
| C83.1 | Mantle cell lymphoma |
| C83.10 | Mantle cell lymphoma, unspecified site |
| C83.11 | Mantle cell lymphoma, lymph nodes of head, face, and neck |
| C83.12 | Mantle cell lymphoma, intrathoracic lymph nodes |
| C83.13 | Mantle cell lymphoma, intra-abdominal lymph nodes |
| C83.14 | Mantle cell lymphoma, lymph nodes of axilla and upper limb |
| C83.15 | Mantle cell lymphoma, lymph nodes of inguinal region and lower limb |
| C83.16 | Mantle cell lymphoma, intrapelvic lymph nodes |
| C83.17 | Mantle cell lymphoma, spleen |
| C83.18 | Mantle cell lymphoma, lymph nodes of multiple sites |
| C83.19 | Mantle cell lymphoma, extranodal and solid organ sites |
| C90.0 | Multiple myeloma |
| C90.00 | Multiple myeloma not having achieved remission |
| C90.02 | Multiple myeloma in relapse |
Formulary Reference Tool