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VANTAS (HISTRELIN ACETATE)
- Advanced prostatic carcinoma
50 mg (50 mcg/day) implant kit
- Dosage information is not available
50 mg (65 mcg/day) implant kit
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- None
- Pregnancy
Contraindicated
- Chronic heart failure
- Congenital long QT syndrome
- Hypokalemia
- Hypomagnesemia
- Prolonged QT interval
Severe
Moderate
- Acute myocardial infarction
- Cerebrovascular accident
- Diabetes mellitus
- Hypercholesterolemia
- Hypertension
- Increased cardiovascular event risk
- Obesity
- Tobacco smoker
- Vertebral metastases
VANTAS (HISTRELIN ACETATE)
- Advanced prostatic carcinoma
- None
- Bruising
- Drug-induced hot flash
- Fatigue
- Flushing
- Treatment site sequelae
More Frequent
Severe
Less Severe
- Depression
- Pain
- Constipation
- Dizziness
- Erectile dysfunction
- Erythema
- Genital organ pruritus
- Gynecomastia
- Headache disorder
- Hematoma
- Increased urinary frequency
- Insomnia
- Libido changes
- Skin inflammation
- Testicular atrophy
- Tremor
- Weight gain
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Anemia
- Arthralgias
- Back pain
- Body fluid retention
- Bone pain
- Cerebrovascular accident
- Diabetes mellitus
- Disease of liver
- Dyspnea
- Dysuria
- Hematuria
- Hypercalcemia
- Kidney disease with reduction in GFR
- Kidney stone
- Mastalgia
- Myalgias
- Neck pain
- Palpitations
- Pituitary apoplexy
- Pruritus of skin
- Seizure disorder
- Spinal cord compression
- Tonic clonic seizure
- Twitching
- Urinary retention
- Ventricular premature beats
Less Severe
- Abnormal sexual function
- Acute abdominal pain
- Dysmenorrhea
- General weakness
- Hypercholesterolemia
- Hyperglycemia
- Hyperhidrosis
- Increased appetite
- Infection
- Irritability
- Lethargy
- Limb pain
- Malaise
- Nausea
- Night sweats
- Peripheral edema
- Sensation of cold
- Skin swelling
- Weight loss
Contraindicated
None
Severe Precaution
Histrelin
No safety and efficacy age < 2 years. Not recommended.
- 1 Day – 2 Years
- No safety and efficacy age < 2 years. Not recommended.
Management or Monitoring Precaution
None
Histrelin
- Severity Level:
1
- Additional Notes: Based on drug pharmacology developmental toxicity is possible.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Histrelin
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Advanced prostatic carcinoma | |
| C61 | Malignant neoplasm of prostate |
| 0-9 | A-Z |
|---|---|
| C61 | Malignant neoplasm of prostate |
Formulary Reference Tool