NIGHTTIME SLEEP-AID (DOXYLAMINE SUCCINATE)
- Urticaria
- Allergic conjunctivitis
- Allergic rhinitis
- Dermatographic urticaria
- Nasal congestion
- Pruritus of skin
- Rhinorrhea
- Sneezing
- Wal-som (doxylamine) Tablet
- Unisom (doxylamine) Tablet
- Sleep Aid (doxylamine) Tablet
- Nighttime Sleep-aid (doxylamine) Tablet
(doxylamine) 25 mg tablet
- Dosage information is not available
(doxylamine) 25 mg tablet
- Dosage information is not available
(doxylamine) 25 mg tablet
- Dosage information is not available
(doxylamine) 25 mg tablet
- Dosage information is not available
Nighttime Sleep-Aid (doxylamine) 25 mg tablet
- Dosage information is not available
- Azilect
- Eldepryl
- isocarboxazid
- linezolid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- rasagiline
- selegiline HCl
- tranylcypromine
- Zelapar
- Zyvox
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- Angle-closure glaucoma
- Benign prostatic hyperplasia
- Bladder outflow obstruction
- Chronic idiopathic constipation
- Stenosing peptic ulcer
- Urinary retention
Severe
Moderate
- Hypertension
- Hyperthyroidism
- Ocular hypertension
NIGHTTIME SLEEP-AID (DOXYLAMINE SUCCINATE)
- Urticaria
- Allergic conjunctivitis
- Allergic rhinitis
- Dermatographic urticaria
- Nasal congestion
- Pruritus of skin
- Rhinorrhea
- Sneezing
- None
- Dizziness
- Drowsy
- Thick bronchial secretions
More Frequent
Severe
Less Severe
- None
- Sedation
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Blood dyscrasias
- Extrasystoles
- Hallucinations
- Hemolytic anemia
- Hypotension
- Seizure disorder
Less Severe
- Abdominal distension
- Acute abdominal pain
- Acute confusion
- Anorexia
- Ataxia
- Blurred vision
- Chest discomfort
- Chills
- Constipation
- Diarrhea
- Diplopia
- Dry nose
- Dry throat
- Dyspnea
- Dysuria
- Euphoria
- Excitement
- Fatigue
- Headache disorder
- Hyperhidrosis
- Insomnia
- Irritability
- Maculopapular rash
- Malaise
- Migraine
- Nervousness
- Nightmares
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin photosensitivity
- Skin rash
- Symptoms of anxiety
- Tachycardia
- Tinnitus
- Tremor
- Urinary retention
- Urticaria
- Vertigo
- Visual changes
- Wheezing
- Xerostomia
Contraindicated
Doxylamine
CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.
- 1 Day – 2 Years
- 1 CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.
Severe Precaution
Doxylamine
CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.
- 2 Years – 6 Years
- CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.
Management or Monitoring Precaution
Doxylamine (Sedative_Hypnotic)
Not recommended age < 12 years as a sleep aid. Risk of paradoxical CNS stimulation.
- 6 Years – 12 Years
- Not recommended age < 12 years as a sleep aid. Risk of paradoxical CNS stimulation.
Doxylamine
- Severity Level:
2
- Additional Notes: Compatible per briggs;overwhelming human and animal data suggests compatibility
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Doxylamine
Low molec wt. possible excretion; not recom; may cause paradoxical excitation
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Low molec wt. possible excretion; not recom; may cause paradoxical excitation |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Doxylamine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Non-sedating antihistamine preferred. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | N | N | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- None
Allergic conjunctivitis | |
H10.1 | Acute atopic conjunctivitis |
H10.10 | Acute atopic conjunctivitis, unspecified eye |
H10.11 | Acute atopic conjunctivitis, right eye |
H10.12 | Acute atopic conjunctivitis, left eye |
H10.13 | Acute atopic conjunctivitis, bilateral |
H10.44 | Vernal conjunctivitis |
H10.45 | Other chronic allergic conjunctivitis |
H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
Allergic rhinitis | |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
Dermatographic urticaria | |
L50.3 | Dermatographic urticaria |
Nasal congestion | |
R09.81 | Nasal congestion |
Pruritus of skin | |
L29.8 | Other pruritus |
L29.9 | Pruritus, unspecified |
Rhinorrhea | |
R09.82 | Postnasal drip |
Sneezing | |
R06.7 | Sneezing |
Urticaria | |
L50 | Urticaria |
L50.0 | Allergic urticaria |
L50.1 | Idiopathic urticaria |
L50.2 | Urticaria due to cold and heat |
L50.3 | Dermatographic urticaria |
L50.4 | Vibratory urticaria |
L50.5 | Cholinergic urticaria |
L50.6 | Contact urticaria |
L50.8 | Other urticaria |
L50.9 | Urticaria, unspecified |
L56.3 | Solar urticaria |
O26.86 | Pruritic urticarial papules and plaques of pregnancy (PUPPp) |
0-9 | A-Z |
---|---|
H10.1 | Acute atopic conjunctivitis |
H10.10 | Acute atopic conjunctivitis, unspecified eye |
H10.11 | Acute atopic conjunctivitis, right eye |
H10.12 | Acute atopic conjunctivitis, left eye |
H10.13 | Acute atopic conjunctivitis, bilateral |
H10.44 | Vernal conjunctivitis |
H10.45 | Other chronic allergic conjunctivitis |
H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
J30.1 | Allergic rhinitis due to pollen |
J30.2 | Other seasonal allergic rhinitis |
J30.5 | Allergic rhinitis due to food |
J30.8 | Other allergic rhinitis |
J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
J30.89 | Other allergic rhinitis |
J30.9 | Allergic rhinitis, unspecified |
L29.8 | Other pruritus |
L29.9 | Pruritus, unspecified |
L50 | Urticaria |
L50.0 | Allergic urticaria |
L50.1 | Idiopathic urticaria |
L50.2 | Urticaria due to cold and heat |
L50.3 | Dermatographic urticaria |
L50.3 | Dermatographic urticaria |
L50.4 | Vibratory urticaria |
L50.5 | Cholinergic urticaria |
L50.6 | Contact urticaria |
L50.8 | Other urticaria |
L50.9 | Urticaria, unspecified |
L56.3 | Solar urticaria |
O26.86 | Pruritic urticarial papules and plaques of pregnancy (PUPPp) |
R06.7 | Sneezing |
R09.81 | Nasal congestion |
R09.82 | Postnasal drip |