ELYXYB (celecoxib)
- migraine headache
120 mg/4.8 mL (25 mg/mL) oral solution
- 4.8 milliliters (120 mg) by oral route once as needed
Default screening record
- 2.4 milliliters (60 mg) by oral route once
- 2.4 milliliters (60 mg) by oral route once as needed
- 4.8 milliliters (120 mg) by oral route once
- 4.8 milliliters (120 mg) by oral route once as needed
- cidofovir
- ketorolac
- Sprix
- Vistide
Contraindicated
- Alimta
- apixaban
- colistin (colistimethate Na)
- Coly-mycin M Parenteral
- Coumadin
- Curad Enema
- Disposable Enema
- Eliquis
- Enema
- Enema Disposable
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- Folotyn
- Jantoven
- Korlym
- Methotrexate (anti-rheumatic)
- methotrexate sodium
- methotrexate sodium (PF)
- mifepristone
- Oral Saline Laxative
- Osmoprep
- pemetrexed
- Phosphate Laxative
- pralatrexate
- Preparation Cleansing
- Ready-to-use Enema
- Rheumatrex
- rivaroxaban
- sod phos mono-sod phos dibasic
- sodium phosphates
- Trexall
- warfarin
- Xarelto
Severe
Moderate
- A-hydrocort
- A-methapred
- abciximab
- Accolate
- Accupril
- Accuretic
- acebutolol
- Aceon
- adefovir
- Adult Low Dose Aspirin
- Aggrenox
- Alka-seltzer
- Alka-seltzer Extra Strength
- Alka-seltzer Original
- Alka-seltzer Pm
- Altace
- amiloride
- amiloride-hydrochlorothiazide
- amiodarone
- amiodarone in dextrose,iso-osm
- amlodipine-benazepril
- amlodipine-olmesartan
- amlodipine-valsartan
- amlodipine-valsartan-hcthiazid
- Angeliq
- Antacid & Pain Relief
- Anucort-hc
- Anusol-hc
- Aristospan Intra-articular
- Aristospan Intralesional
- Arixtra
- ASA-acetaminophen-caff-buffers
- Aspir-81
- Aspir-low
- Aspir-trin
- aspirin
- Aspirin Childrens
- Aspirin Low Dose
- Aspirin Low-strength
- aspirin, buffered
- aspirin-calcium carbonate
- aspirin-diphenhydramine
- aspirin-sod bicarb-citric acid
- Astagraf Xl
- Atacand
- Atacand Hct
- atenolol
- atenolol-chlorthalidone
- Atripla
- Avalide
- Avapro
- azilsartan med-chlorthalidone
- azilsartan medoxomil
- Azor
- Bayer Advanced
- Bayer Aspirin
- Bayer Chewable Aspirin
- Bayer Childrens Aspirin
- Bayer Plus Extra Strength
- benazepril
- benazepril-hydrochlorothiazide
- Benicar
- Benicar Hct
- betamethasone acet & sod phos
- Betapace
- Betapace Af
- betaxolol
- Beyaz
- bisoprolol fumarate
- bisoprolol-hydrochlorothiazide
- Brevibloc
- Brevibloc In Nacl (iso-osm)
- Brilinta
- Brintellix
- Brisdelle
- budesonide
- Buffered Aspirin
- Bufferin
- bumetanide
- Bystolic
- candesartan
- candesartan-hydrochlorothiazid
- captopril
- captopril-hydrochlorothiazide
- Celestone Soluspan
- Celexa
- Child Aspirin
- Children's Aspirin
- cilostazol
- cisplatin
- citalopram
- clopidogrel
- colchicine-probenecid
- Colocort
- Complera
- Cordarone
- Corgard
- Cortef
- Cortenema
- Cortifoam
- cortisone
- Corzide
- Cozaar
- cyclosporine
- cyclosporine modified
- Cymbalta
- Daflonex-xl
- dalteparin (porcine)
- Demadex
- Depo-medrol
- desvenlafaxine
- desvenlafaxine fumarate
- desvenlafaxine succinate
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Diflucan
- diosmin complex no.1
- Diovan Hct
- dipyridamole-aspirin
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- duloxetine
- Dutoprol
- Dyazide
- Dyrenium
- E.c. Prin
- Ecotrin
- Ecotrin Low Strength
- Edarbi
- Edarbyclor
- efavirenz-emtricitabin-tenofov
- Efferves Pain Relief Antacid
- Effervescent Antacid
- Effervescent Pain Relief
- Effervescent Pain Reliever
- Effexor Xr
- Elmiron
- elvitegr-cobicist-emtric-tenof
- emtricitab-rilpivirine-tenofov
- emtricitabine-tenofovir
- enalapril maleate
- enalapril-hydrochlorothiazide
- enalaprilat
- enoxaparin
- Enteric Coated Aspirin
- Entocort Ec
- Epaned
- eprosartan
- eprosartan-hydrochlorothiazide
- eptifibatide
- erlotinib
- escitalopram oxalate
- esmolol
- esmolol in NaCl (iso-osm)
- ethacrynate sodium
- Exforge
- Exforge Hct
- Extra Strength Bayer
- Ez Use Joint-tunnel-trigger
- Fetzima
- First-duke's
- First-mary's Mouthwash
- Flo-pred
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- fludrocortisone
- fluoxetine
- fluvoxamine
- fondaparinux
- fosinopril
- fosinopril-hydrochlorothiazide
- Fragmin
- furosemide
- Gengraf
- Gianvi (28)
- Grx Hicort 25
- Hecoria
- Hemril-30
- heparin (porcine)
- heparin (porcine) in D5W
- heparin(porcine) in 0.45% NaCl
- heparin, porcine (PF)
- Hepsera
- hesp-diosm hyd-Ca dobe-diosmin
- hesperid-diosmin-grape seed xt
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- Hyzaar
- Inderal La
- Inderal Xl
- Innopran Xl
- Integrilin
- irbesartan
- irbesartan-hydrochlorothiazide
- Kenalog
- ketoconazole
- Khedezla
- Lasix
- Levatol
- levomilnacipran
- Lexapro
- lisinopril
- lisinopril-hydrochlorothiazide
- Lite Coat Aspirin
- lithium carbonate
- lithium citrate
- Lithobid
- Lo-dose Aspirin
- Lopressor
- Lopressor Hct
- Loryna (28)
- losartan
- losartan-hydrochlorothiazide
- Lotensin
- Lotrel
- Lovenox
- Luvox Cr
- Mavik
- Maxzide
- Maxzide-25Mg
- Medi-seltzer
- Medrol
- Medrol (pak)
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Micardis
- Micardis Hct
- miconazole
- Millipred
- Millipred Dp
- milnacipran
- moexipril
- moexipril-hydrochlorothiazide
- nadolol
- nadolol-bendroflumethiazide
- nebivolol
- Neoral
- Nexterone
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Ocella
- olanzapine-fluoxetine
- olmesartan
- olmesartan-amlodipin-hcthiazid
- olmesartan-hydrochlorothiazide
- Orapred
- Orapred Odt
- Oravig
- Oxandrin
- oxandrolone
- Pacerone
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- Pediapred
- penbutolol
- pentosan polysulfate sodium
- perindopril erbumine
- Pexeva
- Physicians Ez Use M-pred
- pindolol
- Plavix
- Pletal
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- Prinivil
- Pristiq
- probenecid
- Proctocort
- Prograf
- propranolol
- propranolol-hydrochlorothiazid
- Prozac
- Prozac Weekly
- quinapril
- quinapril-hydrochlorothiazide
- ramipril
- Rapamune
- Rayos
- Rectacort-hc
- Reopro
- Safyral
- Sandimmune
- Sarafem
- Savella
- Sectral
- sertraline
- sirolimus
- Sodium Edecrin
- Soltamox
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Sorine
- sotalol
- Sotalol Af
- St Joseph Aspirin
- St. Joseph Aspirin
- Stribild
- Syeda
- Symbyax
- tacrolimus
- tamoxifen
- Tarceva
- Tarka
- telmisartan
- telmisartan-amlodipine
- telmisartan-hydrochlorothiazid
- tenofovir disoproxil fumarate
- Tenoretic 100
- Tenoretic 50
- Tenormin
- Teveten
- Teveten Hct
- ticagrelor
- timolol maleate
- Toprol Xl
- torsemide
- trandolapril
- trandolapril-verapamil
- Tri-buffered Aspirin
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- triamterene
- triamterene-hydrochlorothiazid
- Tribenzor
- Trombonex-d
- Truvada
- Twynsta
- Uceris
- Uniretic
- Univasc
- valsartan-hydrochlorothiazide
- Vanquish
- Vasculera
- Vaseretic
- Vasoflex Hd
- Vasotec
- Venaliv
- venlafaxine
- Veripred 20
- Vestura (28)
- Vfend
- Vfend Iv
- Viibryd
- vilazodone
- Viread
- vit C-but.broom-hesperidn-dios
- vit C-dios-rut-bioflav-butc br
- voriconazole
- vortioxetine
- Women's Aspirin With Calcium
- Yasmin (28)
- Yaz 28
- zafirlukast
- Zarah
- Zebeta
- Zestoretic
- Zestril
- Ziac
- Zoloft
- Aspirin exacerbated respiratory disease
- Cerebrovascular accident
- History of kidney donation
- History of roux-en-Y gastric bypass
- Post-operative from CABG surgery
- Pregnancy
- Renal transplant
Contraindicated
- Acute myocardial infarction
- Alcoholism
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Chronic kidney disease stage 5 (failure) GFr<15 ml/min
- CYp2c9 intermediate metabolizer (activity score 1)
- CYp2c9 poor metabolizer
- Gastrointestinal hemorrhage
- Gastrointestinal perforation
- Gastrointestinal ulcer
- Increased risk of bleeding
- Kidney disease with likely reduction in GFR
- Peptic ulcer
- Systemic mastocytosis
- Thrombotic disorder
- Tobacco smoker
Severe
Moderate
- Abnormal hepatic function tests
- Anemia
- Asthma
- Chronic heart failure
- Dehydration
- Disease of liver
- Edema
- Hypertension
ELYXYB (celecoxib)
- migraine headache
- Abnormal hepatic function tests
- Accidental injury
- Increased alanine transaminase
- Increased aspartate transaminase
- Acute abdominal pain
- Diarrhea
- Dizziness
- Dysgeusia
- Dyspepsia
- Flatulence
- Peripheral edema
- Pharyngitis
- Rhinitis
- Skin rash
- Upper respiratory infection
More Frequent
Severe
Less Severe
- None
- Back pain
- Epicondylitis
- Headache disorder
- Insomnia
- Nausea
- Sinusitis
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute generalized exanthematous pustulosis
- Acute myocardial infarction
- Agranulocytosis
- Anaphylaxis
- Anemia
- Angina
- Angioedema
- Aplastic anemia
- Biliary calculus
- Bloody stools
- Bronchospastic pulmonary disease
- Cellulitis
- Cerebrovascular accident
- Conjunctival hemorrhage
- Coronary artery disease
- Cystitis
- Deep venous thrombosis
- Diverticulitis of gastrointestinal tract
- DRESS syndrome
- Edema
- Erythema multiforme
- Esophageal perforation
- Esophagitis
- Exfoliative dermatitis
- Facial edema
- Gastroesophageal reflux disease
- Gastrointestinal hemorrhage
- Gastrointestinal obstruction
- Gastrointestinal perforation
- Gastrointestinal ulcer
- Heart failure
- Hematuria
- Hemorrhage
- Hepatic failure
- Hepatic necrosis
- Hepatitis
- Hiatal hernia
- Hypercholesterolemia
- Hyperglycemia
- Hyperkalemia
- Hypernatremia
- Hypertension
- Hypoglycemic disorder
- Hypokalemia
- Hyponatremia
- Interstitial nephritis
- Intracranial bleeding
- Jaundice
- Kidney stone
- Left ventricular hypertrophy
- Leukopenia
- Nephrotoxicity
- Non-infective meningitis
- Pancreatitis
- Pancytopenia
- Pneumonia
- Proteinuria
- Renal papillary necrosis
- Sepsis
- Sinus bradycardia
- Stevens-johnson syndrome
- Syncope
- Tendon rupture
- Thrombocytopenic disorder
- Thrombocytosis
- Thrombophlebitis
- Toxic epidermal necrolysis
- Vasculitis
- Vertigo
Less Severe
- Allergic dermatitis
- Alopecia
- Anorexia
- Arthralgia
- Ataxia
- Body fluid retention
- Bronchitis
- Chest pain
- Constipation
- Contact dermatitis
- Cough
- Cramps in legs
- Depression
- Drowsy
- Dry skin
- Dysphagia
- Dyspnea
- Dysuria
- Ecchymosis
- Epistaxis
- Eructation
- Fatigue
- Fever
- Flu-like symptoms
- Flushing
- Gastritis
- Gastroenteritis
- General weakness
- Hearing loss
- Hemorrhoids
- Hyperhidrosis
- Hypertonia
- Hypoesthesia
- Increased appetite
- Increased urinary frequency
- Laryngitis
- Loss of sense of smell
- Loss of taste
- Maculopapular rash
- Medication overuse headache
- Migraine
- Myalgia
- Nervousness
- Ocular pain
- Ovarian cyst
- Pain
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin irritation
- Skin photosensitivity
- Stomatitis
- Symptoms of anxiety
- Synovitis
- Tachycardia
- Tenesmus
- Tinnitus
- Urticaria
- Vomiting
- Weight gain
- Xerostomia
Contraindicated
None
Severe Precaution
Celecoxib (migraine)
Safety and effectiveness not established in pediatric patients. Risk of disseminated intravascular coagulation in pediatric patients.
- 1 Day – 18 Years
- Safety and effectiveness not established in pediatric patients. Risk of disseminated intravascular coagulation in pediatric patients.
Management or Monitoring Precaution
None
Celecoxib
- Severity Level:
1
- Additional Notes: Not recommended near or after 20 weeks gestation
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Celecoxib
Limited data;Minimal milk and infant blood levels;No adv events yet reported.
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data;Minimal milk and infant blood levels;No adv events yet reported. |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Celecoxib
Gastrointestinal-Risk for ulceration or serious GI bleed; highest with history of PUD or GI bleed. Renal-Risk of AKI and exacerbation of CKD. Avoid with CrCl <30 mL/min. Cardiovascular-May exacerbate pre-existing hypertension or CHF. Risk of MI and stroke. This risk may occur early in treatment and increases with duration of use. Risk for reinfarction with minimal NSAID use post-MI. Contraindicated with CABG. Hepatic-Elevated hepatic transaminases may occur with chronic use.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: Y HEDIS: Y STOPP: Y
No Known Risk
None
- Nonsteroidal anti-inflammatory drugs (including celecoxib) may rarely increase the risk of a heart attack or stroke. This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater in older adults or if you have heart disease or increased risk for heart disease (for example, due to smoking, family history of heart disease, or conditions such as high blood pressure or diabetes).<br /><br />Do not take this drug right before or after heart bypass surgery (CABG). Also, this drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. This effect can occur without warning symptoms at any time while taking this drug.<br /><br /> Older adults may be at higher risk for this effect. Stop taking celecoxib and get medical help right away if you notice any of these rare but serious side effects: stomach/abdominal pain that doesn't go away, black/tarry stools, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, confusion, weakness on one side of the body, trouble speaking, sudden vision changes. Talk to your doctor or pharmacist about the benefits and risks of taking this drug.
Migraine | |
G43 | Migraine |
G43.0 | Migraine without aura |
G43.00 | Migraine without aura, not intractable |
G43.001 | Migraine without aura, not intractable, with status migrainosus |
G43.009 | Migraine without aura, not intractable, without status migrainosus |
G43.01 | Migraine without aura, intractable |
G43.011 | Migraine without aura, intractable, with status migrainosus |
G43.019 | Migraine without aura, intractable, without status migrainosus |
G43.1 | Migraine with aura |
G43.10 | Migraine with aura, not intractable |
G43.101 | Migraine with aura, not intractable, with status migrainosus |
G43.109 | Migraine with aura, not intractable, without status migrainosus |
G43.11 | Migraine with aura, intractable |
G43.111 | Migraine with aura, intractable, with status migrainosus |
G43.119 | Migraine with aura, intractable, without status migrainosus |
G43.4 | Hemiplegic migraine |
G43.40 | Hemiplegic migraine, not intractable |
G43.41 | Hemiplegic migraine, intractable |
G43.7 | Chronic migraine without aura |
G43.70 | Chronic migraine without aura, not intractable |
G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
G43.71 | Chronic migraine without aura, intractable |
G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
G43.8 | Other migraine |
G43.80 | Other migraine, not intractable |
G43.801 | Other migraine, not intractable, with status migrainosus |
G43.809 | Other migraine, not intractable, without status migrainosus |
G43.81 | Other migraine, intractable |
G43.811 | Other migraine, intractable, with status migrainosus |
G43.819 | Other migraine, intractable, without status migrainosus |
G43.82 | Menstrual migraine, not intractable |
G43.821 | Menstrual migraine, not intractable, with status migrainosus |
G43.829 | Menstrual migraine, not intractable, without status migrainosus |
G43.83 | Menstrual migraine, intractable |
G43.831 | Menstrual migraine, intractable, with status migrainosus |
G43.839 | Menstrual migraine, intractable, without status migrainosus |
G43.9 | Migraine, unspecified |
G43.90 | Migraine, unspecified, not intractable |
G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
G43.91 | Migraine, unspecified, intractable |
G43.911 | Migraine, unspecified, intractable, with status migrainosus |
G43.919 | Migraine, unspecified, intractable, without status migrainosus |
G43.B | Ophthalmoplegic migraine |
G43.B0 | Ophthalmoplegic migraine, not intractable |
G43.B1 | Ophthalmoplegic migraine, intractable |
G43.C | Periodic headache syndromes in child or adult |
G43.C0 | Periodic headache syndromes in child or adult, not intractable |
G43.C1 | Periodic headache syndromes in child or adult, intractable |
G43.D | Abdominal migraine |
G43.D0 | Abdominal migraine, not intractable |
G43.D1 | Abdominal migraine, intractable |
G43.E | Chronic migraine with aura |
G43.E0 | Chronic migraine with aura, not intractable |
G43.E01 | Chronic migraine with aura, not intractable, with status migrainosus |
G43.E09 | Chronic migraine with aura, not intractable, without status migrainosus |
G43.E1 | Chronic migraine with aura, intractable |
G43.E11 | Chronic migraine with aura, intractable, with status migrainosus |
G43.E19 | Chronic migraine with aura, intractable, without status migrainosus |
0-9 | A-Z |
---|---|
G43 | Migraine |
G43.0 | Migraine without aura |
G43.00 | Migraine without aura, not intractable |
G43.001 | Migraine without aura, not intractable, with status migrainosus |
G43.009 | Migraine without aura, not intractable, without status migrainosus |
G43.01 | Migraine without aura, intractable |
G43.011 | Migraine without aura, intractable, with status migrainosus |
G43.019 | Migraine without aura, intractable, without status migrainosus |
G43.1 | Migraine with aura |
G43.10 | Migraine with aura, not intractable |
G43.101 | Migraine with aura, not intractable, with status migrainosus |
G43.109 | Migraine with aura, not intractable, without status migrainosus |
G43.11 | Migraine with aura, intractable |
G43.111 | Migraine with aura, intractable, with status migrainosus |
G43.119 | Migraine with aura, intractable, without status migrainosus |
G43.4 | Hemiplegic migraine |
G43.40 | Hemiplegic migraine, not intractable |
G43.41 | Hemiplegic migraine, intractable |
G43.7 | Chronic migraine without aura |
G43.70 | Chronic migraine without aura, not intractable |
G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
G43.71 | Chronic migraine without aura, intractable |
G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
G43.8 | Other migraine |
G43.80 | Other migraine, not intractable |
G43.801 | Other migraine, not intractable, with status migrainosus |
G43.809 | Other migraine, not intractable, without status migrainosus |
G43.81 | Other migraine, intractable |
G43.811 | Other migraine, intractable, with status migrainosus |
G43.819 | Other migraine, intractable, without status migrainosus |
G43.82 | Menstrual migraine, not intractable |
G43.821 | Menstrual migraine, not intractable, with status migrainosus |
G43.829 | Menstrual migraine, not intractable, without status migrainosus |
G43.83 | Menstrual migraine, intractable |
G43.831 | Menstrual migraine, intractable, with status migrainosus |
G43.839 | Menstrual migraine, intractable, without status migrainosus |
G43.9 | Migraine, unspecified |
G43.90 | Migraine, unspecified, not intractable |
G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
G43.91 | Migraine, unspecified, intractable |
G43.911 | Migraine, unspecified, intractable, with status migrainosus |
G43.919 | Migraine, unspecified, intractable, without status migrainosus |
G43.B | Ophthalmoplegic migraine |
G43.B0 | Ophthalmoplegic migraine, not intractable |
G43.B1 | Ophthalmoplegic migraine, intractable |
G43.C | Periodic headache syndromes in child or adult |
G43.C0 | Periodic headache syndromes in child or adult, not intractable |
G43.C1 | Periodic headache syndromes in child or adult, intractable |
G43.D | Abdominal migraine |
G43.D0 | Abdominal migraine, not intractable |
G43.D1 | Abdominal migraine, intractable |
G43.E | Chronic migraine with aura |
G43.E0 | Chronic migraine with aura, not intractable |
G43.E01 | Chronic migraine with aura, not intractable, with status migrainosus |
G43.E09 | Chronic migraine with aura, not intractable, without status migrainosus |
G43.E1 | Chronic migraine with aura, intractable |
G43.E11 | Chronic migraine with aura, intractable, with status migrainosus |
G43.E19 | Chronic migraine with aura, intractable, without status migrainosus |