Levothyroxine Sodium

LEVOTHYROXINE SODIUM (levothyroxine sodium)

Myxedema coma

Levothyroxine Iv Solution
Levothyroxine Intravenous Solution
By Indication

levothyroxine 100 mcg intravenous powder for solution

Inject 50 mcg by intravenous route once daily

levothyroxine 200 mcg intravenous powder for solution

Inject 50 mcg by intravenous route once daily

levothyroxine 500 mcg intravenous powder for solution

Inject 50 mcg by intravenous route once daily

levothyroxine 100 mcg intravenous powder for solution

Inject 50 mcg by intravenous route once daily

levothyroxine 200 mcg intravenous powder for solution

Inject 50 mcg by intravenous route once daily

levothyroxine 500 mcg intravenous powder for solution

Inject 50 mcg by intravenous route once daily

Myxedema coma

Inject 50 mcg by intravenous route once daily

Inject 100 mcg by intravenous route once daily

Inject 100 mcg by intravenous route once

Inject 300 mcg by intravenous route once

Inject 500 mcg by intravenous route once

More Frequent & Less Frequent(results - 2) (results - 3)
Rare / Very Rare(results 37)

LEVOTHYROXINE SODIUM (levothyroxine sodium)

Myxedema coma

More Frequent

Severe

None

Less Severe

Female infertility

Less Frequent

Severe

Osteopenia

Less Severe

Hypertension
Weight loss

Rare / Very Rare

Severe

Abnormal hepatic function tests

Acute myocardial infarction

Allergic dermatitis

Angina

Angioedema

Cardiac arrest

Cardiac arrhythmia

Dyspnea

Heart failure

Idiopathic intracranial hypertension

Mood changes

Seizure disorder

Skin rash

Tachycardia

Urticaria

Less Severe

Abdominal pain with cramps

Alopecia

Diarrhea

Fatigue

Fever

Flushing

Headache disorder

Heat intolerance

Hyperhidrosis

Increased appetite

Insomnia

Irregular menstrual periods

Irritability

Menstrual disorder

Muscle spasm

Muscle weakness

Nervousness

Palpitations

Pulse changes

Symptoms of anxiety

Tremor

Vomiting

Contraindicated

None

Severe Precaution

None

Management or Monitoring Precaution

Levothyroxine

Monitor closely to avoid adverse effects on intellectual development, brain maturation, and linear growth due to overtreatment or undertreatment. Rare reports of pseudotumor cerebri and slipped capital femoral epiphysis.

1 Day – 18 Years
Monitor closely to avoid adverse effects on intellectual development, brain maturation, and linear growth due to overtreatment or undertreatment. Rare reports of pseudotumor cerebri and slipped capital femoral epiphysis.

Levothyroxine Sodium

Severity Level:
2
Additional Notes: Human data suggest no known dev tox; monitor tsh for possible dose increases

Contraindicated

None

General	Excretion Potential	Effect on Infant	Notes
			None

Precaution Exists

None

General	Excretion Potential	Effect on Infant	Notes
			None

No Known Risk

Levothyroxine Sodium

Limited data suggest no adverse effects on infant

General	Excretion Potential	Effect on Infant	Notes
No known risks; does not adversely affect lactation	Excreted	No adverse effect	Limited data suggest no adverse effects on infant

Contraindicated

None

Precaution Exists

Levothyroxine

General-Elderly may be more sensitive to l-thyroxine. Start at lower dose. Cardiovascular-Use caution and start at lower doses in those patients with cardiac disease, particularly atrial fibrillation.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	N	N	Y	Y	N	Y

BEERS: N HEDIS: N STOPP: N

No Known Risk

None