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ZOLADEX (GOSERELIN ACETATE)
- Advanced prostatic carcinoma
- Advanced prostatic carcinoma
- Hormone receptor positive breast cancer
- Prostatic carcinoma
- Endometrial ablation adjunct
- Endometriosis
10.8 mg subcutaneous implant
- Inject 10.8 mg by subcutaneous route every 12 weeks
3.6 mg subcutaneous implant
- Inject 3.6 mg by subcutaneous route every 28 days
Advanced prostatic carcinoma
- Inject 3.6 mg by subcutaneous route every 28 days
- Inject 10.8 mg by subcutaneous route every 12 weeks
Endometrial ablation adjunct
- Inject 3.6 mg by subcutaneous route every 28 days
- Inject 3.6 mg by subcutaneous route x1 dose
- Inject 3.6 mg by subcutaneous route every 28 days x2 doses
Endometriosis
- Inject 3.6 mg by subcutaneous route every 28 days
- Inject 3.6 mg by subcutaneous route every 28 days for 6 months
- None
Contraindicated
- None
Severe
Moderate
- None
- Pregnancy
Contraindicated
- Congenital long QT syndrome
- Hypocalcemia
- Hypokalemia
- Hypomagnesemia
- Prolonged QT interval
Severe
Moderate
- Acute myocardial infarction
- Bone metastases
- Cerebrovascular accident
- Chronic heart failure
- Diabetes mellitus
- Hypercalcemia
- Hypercholesterolemia
- Hypertension
- Increased cardiovascular event risk
- Obesity
- Tobacco smoker
- Urinary tract obstruction
ZOLADEX (GOSERELIN ACETATE)
- Advanced prostatic carcinoma
- Advanced prostatic carcinoma
- Hormone receptor positive breast cancer
- Prostatic carcinoma
- Endometrial ablation adjunct
- Endometriosis
- Angina
- Diabetes mellitus
- Dyspnea
- Acne vulgaris
- Arthralgias
- Breast size decreased
- Depression
- Drug-induced hot flash
- Erectile dysfunction
- Flu-like symptoms
- Headache disorder
- Hyperglycemia
- Hyperhidrosis
- Injection site sequelae
- Libido changes
- Mood changes
- Peripheral edema
- Seborrhea
- Urinary incontinence
- Urinary retention
- Vaginitis
More Frequent
Severe
Less Severe
- Anemia
- Bone pain
- Cardiac arrhythmia
- Chronic heart failure
- Gout
- Hypercalcemia
- Hypertension
- Kidney disease with reduction in GFR
- Osteoporosis
- Peripheral vascular disease
- Pneumonia
- Severe chronic obstructive pulmonary disease
- Skin rash
- Abdominal distension
- Acute abdominal pain
- Alopecia
- Anorexia
- Breast engorgement
- Constipation
- Cough
- Cramps in legs
- Diarrhea
- Dizziness
- Dry eye
- Dry skin
- Dyspareunia
- Edema
- Fatigue
- Fever
- General weakness
- Gynecomastia
- Herpes simplex infection
- Hypertonia
- Hypotension
- Insomnia
- Lethargy
- Malaise
- Mastalgia
- Myalgias
- Nausea
- Pain
- Palpitations
- Paresthesia
- Pelvic pain
- Pruritus of skin
- Symptoms of anxiety
- Upper respiratory infection
- Urinary tract infection
- Vomiting
- Weight gain
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Anaphylaxis
- Cerebrovascular accident
- Deep venous thrombosis
- Drug-induced psychosis
- Hematuria
- Hemorrhage
- Ovarian cyst
- Ovarian hyperstimulation syndrome
- Pituitary apoplexy
- Pituitary neoplasm
- Pulmonary thromboembolism
- Seizure disorder
- Sepsis
- Spinal cord compression
- Urinary tract obstruction
- Urticaria
Less Severe
- Ecchymosis
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Goserelin
No safety and efficacy established.
- 1 Day – 18 Years
- No safety and efficacy established.
Goserelin
- Severity Level:
X
- Additional Notes: Fda cat d for treatment of advanced breast cancer in pre/post-menopausal women
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Goserelin
Insufficient data available
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
Advanced prostatic carcinoma | |
C61 | Malignant neoplasm of prostate |
Endometriosis | |
N80 | Endometriosis |
N80.0 | Endometriosis of uterus |
N80.1 | Endometriosis of ovary |
N80.2 | Endometriosis of fallopian tube |
N80.3 | Endometriosis of pelvic peritoneum |
N80.4 | Endometriosis of rectovaginal septum and vagina |
N80.5 | Endometriosis of intestine |
N80.6 | Endometriosis in cutaneous scar |
N80.8 | Other endometriosis |
N80.9 | Endometriosis, unspecified |
Hormone receptor positive breast cancer | |
C50 | Malignant neoplasm of breast |
C50.1 | Malignant neoplasm of central portion of breast |
C50.11 | Malignant neoplasm of central portion of breast, female |
C50.111 | Malignant neoplasm of central portion of right female breast |
C50.112 | Malignant neoplasm of central portion of left female breast |
C50.119 | Malignant neoplasm of central portion of unspecified female breast |
C50.12 | Malignant neoplasm of central portion of breast, male |
C50.121 | Malignant neoplasm of central portion of right male breast |
C50.122 | Malignant neoplasm of central portion of left male breast |
C50.129 | Malignant neoplasm of central portion of unspecified male breast |
C50.2 | Malignant neoplasm of upper-inner quadrant of breast |
C50.21 | Malignant neoplasm of upper-inner quadrant of breast, female |
C50.211 | Malignant neoplasm of upper-inner quadrant of right female breast |
C50.212 | Malignant neoplasm of upper-inner quadrant of left female breast |
C50.219 | Malignant neoplasm of upper-inner quadrant of unspecified female breast |
C50.22 | Malignant neoplasm of upper-inner quadrant of breast, male |
C50.221 | Malignant neoplasm of upper-inner quadrant of right male breast |
C50.222 | Malignant neoplasm of upper-inner quadrant of left male breast |
C50.229 | Malignant neoplasm of upper-inner quadrant of unspecified male breast |
C50.3 | Malignant neoplasm of lower-inner quadrant of breast |
C50.31 | Malignant neoplasm of lower-inner quadrant of breast, female |
C50.311 | Malignant neoplasm of lower-inner quadrant of right female breast |
C50.312 | Malignant neoplasm of lower-inner quadrant of left female breast |
C50.319 | Malignant neoplasm of lower-inner quadrant of unspecified female breast |
C50.32 | Malignant neoplasm of lower-inner quadrant of breast, male |
C50.321 | Malignant neoplasm of lower-inner quadrant of right male breast |
C50.322 | Malignant neoplasm of lower-inner quadrant of left male breast |
C50.329 | Malignant neoplasm of lower-inner quadrant of unspecified male breast |
C50.4 | Malignant neoplasm of upper-outer quadrant of breast |
C50.41 | Malignant neoplasm of upper-outer quadrant of breast, female |
C50.411 | Malignant neoplasm of upper-outer quadrant of right female breast |
C50.412 | Malignant neoplasm of upper-outer quadrant of left female breast |
C50.419 | Malignant neoplasm of upper-outer quadrant of unspecified female breast |
C50.42 | Malignant neoplasm of upper-outer quadrant of breast, male |
C50.421 | Malignant neoplasm of upper-outer quadrant of right male breast |
C50.422 | Malignant neoplasm of upper-outer quadrant of left male breast |
C50.429 | Malignant neoplasm of upper-outer quadrant of unspecified male breast |
C50.5 | Malignant neoplasm of lower-outer quadrant of breast |
C50.51 | Malignant neoplasm of lower-outer quadrant of breast, female |
C50.511 | Malignant neoplasm of lower-outer quadrant of right female breast |
C50.512 | Malignant neoplasm of lower-outer quadrant of left female breast |
C50.519 | Malignant neoplasm of lower-outer quadrant of unspecified female breast |
C50.52 | Malignant neoplasm of lower-outer quadrant of breast, male |
C50.521 | Malignant neoplasm of lower-outer quadrant of right male breast |
C50.522 | Malignant neoplasm of lower-outer quadrant of left male breast |
C50.529 | Malignant neoplasm of lower-outer quadrant of unspecified male breast |
C50.6 | Malignant neoplasm of axillary tail of breast |
C50.61 | Malignant neoplasm of axillary tail of breast, female |
C50.611 | Malignant neoplasm of axillary tail of right female breast |
C50.612 | Malignant neoplasm of axillary tail of left female breast |
C50.619 | Malignant neoplasm of axillary tail of unspecified female breast |
C50.62 | Malignant neoplasm of axillary tail of breast, male |
C50.621 | Malignant neoplasm of axillary tail of right male breast |
C50.622 | Malignant neoplasm of axillary tail of left male breast |
C50.629 | Malignant neoplasm of axillary tail of unspecified male breast |
C50.8 | Malignant neoplasm of overlapping sites of breast |
C50.81 | Malignant neoplasm of overlapping sites of breast, female |
C50.811 | Malignant neoplasm of overlapping sites of right female breast |
C50.812 | Malignant neoplasm of overlapping sites of left female breast |
C50.819 | Malignant neoplasm of overlapping sites of unspecified female breast |
C50.82 | Malignant neoplasm of overlapping sites of breast, male |
C50.821 | Malignant neoplasm of overlapping sites of right male breast |
C50.822 | Malignant neoplasm of overlapping sites of left male breast |
C50.829 | Malignant neoplasm of overlapping sites of unspecified male breast |
C50.9 | Malignant neoplasm of breast of unspecified site |
C50.91 | Malignant neoplasm of breast of unspecified site, female |
C50.911 | Malignant neoplasm of unspecified site of right female breast |
C50.912 | Malignant neoplasm of unspecified site of left female breast |
C50.919 | Malignant neoplasm of unspecified site of unspecified female breast |
C50.92 | Malignant neoplasm of breast of unspecified site, male |
C50.921 | Malignant neoplasm of unspecified site of right male breast |
C50.922 | Malignant neoplasm of unspecified site of left male breast |
C50.929 | Malignant neoplasm of unspecified site of unspecified male breast |
Z17.0 | Estrogen receptor positive status [Er+] |
Z19.1 | Hormone sensitive malignancy status |
Prostatic carcinoma | |
C61 | Malignant neoplasm of prostate |
0-9 | A-Z |
---|---|
C50 | Malignant neoplasm of breast |
C50.1 | Malignant neoplasm of central portion of breast |
C50.11 | Malignant neoplasm of central portion of breast, female |
C50.111 | Malignant neoplasm of central portion of right female breast |
C50.112 | Malignant neoplasm of central portion of left female breast |
C50.119 | Malignant neoplasm of central portion of unspecified female breast |
C50.12 | Malignant neoplasm of central portion of breast, male |
C50.121 | Malignant neoplasm of central portion of right male breast |
C50.122 | Malignant neoplasm of central portion of left male breast |
C50.129 | Malignant neoplasm of central portion of unspecified male breast |
C50.2 | Malignant neoplasm of upper-inner quadrant of breast |
C50.21 | Malignant neoplasm of upper-inner quadrant of breast, female |
C50.211 | Malignant neoplasm of upper-inner quadrant of right female breast |
C50.212 | Malignant neoplasm of upper-inner quadrant of left female breast |
C50.219 | Malignant neoplasm of upper-inner quadrant of unspecified female breast |
C50.22 | Malignant neoplasm of upper-inner quadrant of breast, male |
C50.221 | Malignant neoplasm of upper-inner quadrant of right male breast |
C50.222 | Malignant neoplasm of upper-inner quadrant of left male breast |
C50.229 | Malignant neoplasm of upper-inner quadrant of unspecified male breast |
C50.3 | Malignant neoplasm of lower-inner quadrant of breast |
C50.31 | Malignant neoplasm of lower-inner quadrant of breast, female |
C50.311 | Malignant neoplasm of lower-inner quadrant of right female breast |
C50.312 | Malignant neoplasm of lower-inner quadrant of left female breast |
C50.319 | Malignant neoplasm of lower-inner quadrant of unspecified female breast |
C50.32 | Malignant neoplasm of lower-inner quadrant of breast, male |
C50.321 | Malignant neoplasm of lower-inner quadrant of right male breast |
C50.322 | Malignant neoplasm of lower-inner quadrant of left male breast |
C50.329 | Malignant neoplasm of lower-inner quadrant of unspecified male breast |
C50.4 | Malignant neoplasm of upper-outer quadrant of breast |
C50.41 | Malignant neoplasm of upper-outer quadrant of breast, female |
C50.411 | Malignant neoplasm of upper-outer quadrant of right female breast |
C50.412 | Malignant neoplasm of upper-outer quadrant of left female breast |
C50.419 | Malignant neoplasm of upper-outer quadrant of unspecified female breast |
C50.42 | Malignant neoplasm of upper-outer quadrant of breast, male |
C50.421 | Malignant neoplasm of upper-outer quadrant of right male breast |
C50.422 | Malignant neoplasm of upper-outer quadrant of left male breast |
C50.429 | Malignant neoplasm of upper-outer quadrant of unspecified male breast |
C50.5 | Malignant neoplasm of lower-outer quadrant of breast |
C50.51 | Malignant neoplasm of lower-outer quadrant of breast, female |
C50.511 | Malignant neoplasm of lower-outer quadrant of right female breast |
C50.512 | Malignant neoplasm of lower-outer quadrant of left female breast |
C50.519 | Malignant neoplasm of lower-outer quadrant of unspecified female breast |
C50.52 | Malignant neoplasm of lower-outer quadrant of breast, male |
C50.521 | Malignant neoplasm of lower-outer quadrant of right male breast |
C50.522 | Malignant neoplasm of lower-outer quadrant of left male breast |
C50.529 | Malignant neoplasm of lower-outer quadrant of unspecified male breast |
C50.6 | Malignant neoplasm of axillary tail of breast |
C50.61 | Malignant neoplasm of axillary tail of breast, female |
C50.611 | Malignant neoplasm of axillary tail of right female breast |
C50.612 | Malignant neoplasm of axillary tail of left female breast |
C50.619 | Malignant neoplasm of axillary tail of unspecified female breast |
C50.62 | Malignant neoplasm of axillary tail of breast, male |
C50.621 | Malignant neoplasm of axillary tail of right male breast |
C50.622 | Malignant neoplasm of axillary tail of left male breast |
C50.629 | Malignant neoplasm of axillary tail of unspecified male breast |
C50.8 | Malignant neoplasm of overlapping sites of breast |
C50.81 | Malignant neoplasm of overlapping sites of breast, female |
C50.811 | Malignant neoplasm of overlapping sites of right female breast |
C50.812 | Malignant neoplasm of overlapping sites of left female breast |
C50.819 | Malignant neoplasm of overlapping sites of unspecified female breast |
C50.82 | Malignant neoplasm of overlapping sites of breast, male |
C50.821 | Malignant neoplasm of overlapping sites of right male breast |
C50.822 | Malignant neoplasm of overlapping sites of left male breast |
C50.829 | Malignant neoplasm of overlapping sites of unspecified male breast |
C50.9 | Malignant neoplasm of breast of unspecified site |
C50.91 | Malignant neoplasm of breast of unspecified site, female |
C50.911 | Malignant neoplasm of unspecified site of right female breast |
C50.912 | Malignant neoplasm of unspecified site of left female breast |
C50.919 | Malignant neoplasm of unspecified site of unspecified female breast |
C50.92 | Malignant neoplasm of breast of unspecified site, male |
C50.921 | Malignant neoplasm of unspecified site of right male breast |
C50.922 | Malignant neoplasm of unspecified site of left male breast |
C50.929 | Malignant neoplasm of unspecified site of unspecified male breast |
C61 | Malignant neoplasm of prostate |
C61 | Malignant neoplasm of prostate |
N80 | Endometriosis |
N80.0 | Endometriosis of uterus |
N80.1 | Endometriosis of ovary |
N80.2 | Endometriosis of fallopian tube |
N80.3 | Endometriosis of pelvic peritoneum |
N80.4 | Endometriosis of rectovaginal septum and vagina |
N80.5 | Endometriosis of intestine |
N80.6 | Endometriosis in cutaneous scar |
N80.8 | Other endometriosis |
N80.9 | Endometriosis, unspecified |
Z17.0 | Estrogen receptor positive status [Er+] |
Z19.1 | Hormone sensitive malignancy status |
Formulary Reference Tool