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ZAFEMY (norelgestromin/ethinyl estradiol)
- birth control
150 mcg-35 mcg/24 hr transdermal patch
- Apply 1 patch by transdermal route once weekly
150 mcg-35 mcg/24 hr transdermal patch
- Apply 1 patch by transdermal route once weekly
Default screening record
- Apply 1 patch by transdermal route once weekly
- Apply 1 patch by transdermal route once weekly for 3 weeks
- anastrozole
- Arimidex
- Aromasin
- Cyklokapron
- exemestane
- Femara
- letrozole
- Lysteda
- sodium tetradecyl sulfate
- Sotradecol
- tranexamic acid
Contraindicated
- Alagesic Lq
- amobarbital
- Amytal
- Aptiom
- artemether-lumefantrine
- Ascomp With Codeine
- Atripla
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Banzel
- Belladonna-phenobarbital
- boceprevir
- bosentan
- Brevital
- Bupap
- butabarbital
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-acetaminop-caf-cod
- butalbital-acetaminophen
- butalbital-acetaminophen-caff
- butalbital-aspirin-caffeine
- Butisol
- calcium-mag-B complex-D3-hrb61
- Capacet
- carbamazepine
- Carbatrol
- Cellcept
- Cellcept Intravenous
- Cerebyx
- chloramphenicol sod succinate
- clobazam
- Coartem
- codeine-butalbital-ASA-caff
- Cold & Flu Fighter
- dabrafenib
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- efavirenz
- efavirenz-emtricitabin-tenofov
- elvitegr-cobicist-emtric-tenof
- Epitol
- Equetro
- Esgic
- eslicarbazepine
- ethotoin
- Fatigue Relief Complex
- felbamate
- Felbatol
- Fioricet
- Fioricet With Codeine
- Fiorinal
- Fiorinal-codeine #3
- fosphenytoin
- Fycompa
- Grifulvin V
- Gris-peg (ultramicrosize)
- griseofulvin microsize
- griseofulvin ultramicrosize
- Incivek
- isoniazid-rifamp-pyrazinamide
- Korlym
- Luminal
- Margesic
- Marten-tab
- methohexital
- mifepristone
- modafinil
- Mycobutin
- mycophenolate mofetil
- mycophenolate mofetil HCl
- mycophenolate sodium
- Myfortic
- Mysoline
- Nembutal Sodium
- nevirapine
- Onfi
- oxcarbazepine
- Oxtellar Xr
- Peganone
- pentobarbital sodium
- perampanel
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- phentermine-topiramate
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Priftin
- primidone
- Provigil
- Qsymia
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- rufinamide
- secobarbital sodium
- Seconal Sodium
- St. John's wort
- Stribild
- Sustiva
- Tafinlar
- Tegretol
- Tegretol Xr
- telaprevir
- Tencon
- tizanidine
- Topamax
- Topiragen
- topiramate
- Tracleer
- Trileptal
- Trokendi Xr
- Victrelis
- Viramune
- Viramune Xr
- vit C-St. John wort-elder-hb30
- Women's Complex
- Zanaflex
- Zebutal
Severe
Moderate
- A-hydrocort
- A-methapred
- aminophylline
- Anucort-hc
- Anusol-hc
- aprepitant
- Aristospan Intra-articular
- Aristospan Intralesional
- betamethasone acet & sod phos
- Bivigam
- budesonide
- Carimune Nf Nanofiltered
- Celestone Soluspan
- Colocort
- Cortef
- Cortenema
- Cortifoam
- cortisone
- Depo-medrol
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Elixophyllin
- Emend
- Entocort Ec
- Evista
- Ez Use Joint-tunnel-trigger
- First-duke's
- First-mary's Mouthwash
- Flebogamma Dif
- Flo-pred
- fludrocortisone
- fosaprepitant
- Gamastan S/d
- Gammagard Liquid
- Gammagard S-d (iga < 1 Mcg/ml)
- Gammagard S/d
- Gammaked
- Gammaplex
- Gamunex-c
- Grx Hicort 25
- Hemril-30
- Hizentra
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- immune glob(IgG)(hum)-maltose
- immune globulin (human) (IgG)
- immune globulin(hum),capr(IgG)
- Kenalog
- Lamictal
- Lamictal Odt
- Lamictal Odt Starter (blue)
- Lamictal Odt Starter (green)
- Lamictal Odt Starter (orange)
- Lamictal Starter (blue) Kit
- Lamictal Starter (green) Kit
- Lamictal Starter (orange) Kit
- Lamictal Xr
- Lamictal Xr Starter (blue)
- Lamictal Xr Starter (green)
- Lamictal Xr Starter (orange)
- lamotrigine
- Medrol
- Medrol (pak)
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- Millipred
- Millipred Dp
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Octagam
- Orapred
- Orapred Odt
- Pediapred
- Physicians Ez Use M-pred
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- Privigen
- Proctocort
- raloxifene
- Rayos
- Rectacort-hc
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Theo-24
- Theochron
- theophylline
- theophylline in dextrose 5 %
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- Uceris
- Veripred 20
- 30 day risk period post-myocardial infarction
- Abnormal uterine bleeding
- Acute myocardial infarction
- Antithrombin III deficiency
- Carcinoma of breast
- Cerebrovascular accident
- Deep venous thrombosis
- Disease of liver
- Estrogen-dependent neoplasm
- Neoplasm of liver
- Porphyria
- Predisposition to thrombosis
- Protein C deficiency disease
- Thromboembolic disorder
- Thrombotic disorder
Contraindicated
- Acute myocardial infarction
- Bed-ridden
- Cerebrovascular accident
- Coronary artery disease
- Deep venous thrombosis
- Endometrial carcinoma
- Hereditary angioedema
- Migraine
- Obesity
- Predisposition to thrombosis
- Pulmonary thromboembolism
- Retinal thrombosis
- Thromboembolic disorder
- Thrombophlebitis
- Tobacco smoker
- Valvular heart disease
Severe
Moderate
- Depression
- Diabetes mellitus
- Edema
- Family history of malignant tumor of breast
- Gallbladder disease
- Hypercholesterolemia
- Hyperlipidemia
- Hypertension
- Hypertriglyceridemia
- Mammography abnormal
- Seizure disorder
- Unspecified lump in breast
ZAFEMY (norelgestromin/ethinyl estradiol)
- birth control
- Upper respiratory infection
- Abnormal vaginal bleeding
- Acute abdominal pain
- Dysmenorrhea
- Edema
- Gynecomastia
- Headache disorder
- Mastalgia
- Menstrual disorder
- Mood changes
- Nausea
- Nipple discharge
- Skin irritation
- Symptoms of anxiety
- Treatment site sequelae
- Vomiting
- Weight gain
More Frequent
Severe
Less Severe
- Change in corneal curvature
- Hypertension
- Acne vulgaris
- Chloasma
- Skin rash
- Vaginal discharge
- Vulvovaginal candidiasis
- Weight loss
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute arterial thromboembolism
- Acute myocardial infarction
- Benign hepatic cell adenoma
- Cerebral thrombosis
- Cholecystitis
- Depression
- Dysplasia of cervix
- Erythema multiforme
- Erythema nodosum
- Gallbladder disease
- Gastrointestinal irritation
- Hemorrhagic stroke
- Hypertensive crisis
- Hypertriglyceridemia
- Neoplasm of breast
- Obstructive hyperbilirubinemia
- Pulmonary thromboembolism
- Retinal thrombosis
- Thromboembolic disorder
- Venous thrombosis
Less Severe
- Alopecia
- Amenorrhea
- Contact dermatitis
- Disorder of lipid metabolism
- Dysgeusia
- Eczema
- Erythema
- Female infertility
- Galactorrhea not associated with childbirth
- Hyperglycemia
- Increased appetite
- Insomnia
- Lactation deficiency
- Libido changes
- Migraine
- Muscle spasm
- Pruritus of skin
- Seborrheic dermatitis
- Skin photosensitivity
- Urticaria
- Vaginal dryness
Contraindicated
None
Severe Precaution
Transdermal Contraceptives
Not indicated before menarche
- 1 Day – 13 Years
- Not indicated before menarche
Management or Monitoring Precaution
None
Norelgestromin-ethinyl Estradiol
- Severity Level:
2
- Additional Notes: Not indicated during pregnancy, no known dev tox with exposure.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Ethinyl Estradiol
May decrease milk production, use lowest dose
May decrease quantity and quality of breastmilk and dec infant weight gain
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Drug shown to have adverse effect | May decrease milk production, use lowest dose |
Norelgestromin
May decrease milk production, use lowest dose
May decrease quantity and quality of breastmilk and dec infant weight gain
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | May decrease quantity and quality of breastmilk and dec infant weight gain |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Do not use this medication if you smoke cigarettes/use tobacco and are over 35 years old. Smoking raises your risk of stroke, heart attack, blood clots, and high blood pressure from hormonal birth control (such as the pill, patch, ring). The risk of these serious problems increases with age and with the number of cigarettes you smoke.<br /><br />Do not smoke or use tobacco. The amount of estrogen you receive when using the patch is higher than the amount from most birth control pills. This may increase the risk for blood clots or other side effects from the patch compared to oral contraceptives. Talk to your doctor for more details.
| Pregnancy contraception | |
| Z30 | Encounter for contraceptive management |
| Z30.01 | Encounter for initial prescription of contraceptives |
| Z30.011 | Encounter for initial prescription of contraceptive pills |
| Z30.013 | Encounter for initial prescription of injectable contraceptive |
| Z30.014 | Encounter for initial prescription of intrauterine contraceptive device |
| Z30.015 | Encounter for initial prescription of vaginal ring hormonal contraceptive |
| Z30.016 | Encounter for initial prescription of transdermal patch hormonal contraceptive device |
| Z30.017 | Encounter for initial prescription of implantable subdermal contraceptive |
| Z30.018 | Encounter for initial prescription of other contraceptives |
| Z30.019 | Encounter for initial prescription of contraceptives, unspecified |
| Z30.4 | Encounter for surveillance of contraceptives |
| Z30.40 | Encounter for surveillance of contraceptives, unspecified |
| Z30.41 | Encounter for surveillance of contraceptive pills |
| Z30.42 | Encounter for surveillance of injectable contraceptive |
| Z30.43 | Encounter for surveillance of intrauterine contraceptive device |
| Z30.430 | Encounter for insertion of intrauterine contraceptive device |
| Z30.431 | Encounter for routine checking of intrauterine contraceptive device |
| Z30.433 | Encounter for removal and reinsertion of intrauterine contraceptive device |
| Z30.44 | Encounter for surveillance of vaginal ring hormonal contraceptive device |
| Z30.45 | Encounter for surveillance of transdermal patch hormonal contraceptive device |
| Z30.46 | Encounter for surveillance of implantable subdermal contraceptive |
| Z30.49 | Encounter for surveillance of other contraceptives |
| Z30.8 | Encounter for other contraceptive management |
| Z30.9 | Encounter for contraceptive management, unspecified |
| Z79.3 | Long term (current) use of hormonal contraceptives |
| Z97.5 | Presence of (intrauterine) contraceptive device |
| 0-9 | A-Z |
|---|---|
| Z30 | Encounter for contraceptive management |
| Z30.01 | Encounter for initial prescription of contraceptives |
| Z30.011 | Encounter for initial prescription of contraceptive pills |
| Z30.013 | Encounter for initial prescription of injectable contraceptive |
| Z30.014 | Encounter for initial prescription of intrauterine contraceptive device |
| Z30.015 | Encounter for initial prescription of vaginal ring hormonal contraceptive |
| Z30.016 | Encounter for initial prescription of transdermal patch hormonal contraceptive device |
| Z30.017 | Encounter for initial prescription of implantable subdermal contraceptive |
| Z30.018 | Encounter for initial prescription of other contraceptives |
| Z30.019 | Encounter for initial prescription of contraceptives, unspecified |
| Z30.4 | Encounter for surveillance of contraceptives |
| Z30.40 | Encounter for surveillance of contraceptives, unspecified |
| Z30.41 | Encounter for surveillance of contraceptive pills |
| Z30.42 | Encounter for surveillance of injectable contraceptive |
| Z30.43 | Encounter for surveillance of intrauterine contraceptive device |
| Z30.430 | Encounter for insertion of intrauterine contraceptive device |
| Z30.431 | Encounter for routine checking of intrauterine contraceptive device |
| Z30.433 | Encounter for removal and reinsertion of intrauterine contraceptive device |
| Z30.44 | Encounter for surveillance of vaginal ring hormonal contraceptive device |
| Z30.45 | Encounter for surveillance of transdermal patch hormonal contraceptive device |
| Z30.46 | Encounter for surveillance of implantable subdermal contraceptive |
| Z30.49 | Encounter for surveillance of other contraceptives |
| Z30.8 | Encounter for other contraceptive management |
| Z30.9 | Encounter for contraceptive management, unspecified |
| Z79.3 | Long term (current) use of hormonal contraceptives |
| Z97.5 | Presence of (intrauterine) contraceptive device |
Formulary Reference Tool