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PROGESTERONE (progesterone)
- Abnormal uterine bleeding due to hormonal imbalance
- Amenorrhea secondary to ovarian dysfunction
50 mg/mL intramuscular oil
- Inject 0.1 milliliter (5 mg) by intramuscular route once daily
Abnormal uterine bleeding due to hormonal imbalance
- Inject 0.1 milliliter (5 mg) by intramuscular route once daily
- Inject 0.1 milliliter (5 mg) by intramuscular route once daily for 6 doses
- Inject 0.2 milliliter (10 mg) by intramuscular route once daily for 6Doses
- Inject 0.2 milliliter (10 mg) by intramuscular route once daily
Amenorrhea secondary to ovarian dysfunction
- Inject 0.1 milliliter (5 mg) by intramuscular route once daily for 6 days
- Inject 0.1 milliliter (5 mg) by intramuscular route once daily for 8 days
- Inject 0.1 milliliter (5 mg) by intramuscular route once daily
- Inject 0.2 milliliter (10 mg) by intramuscular route once daily
- Inject 0.2 milliliter (10 mg) by intramuscular route once daily for 8Days
- Inject 0.2 milliliter (10 mg) by intramuscular route once daily for 6Days
Corpus luteum insufficiency syndrome
- Inject 0.25 milliliter (12.5 mg) by intramuscular route once daily
- Inject 0.25 milliliter (12.5 mg) by intramuscular route once daily for 14 days
- None
Contraindicated
- None
Severe
Moderate
- None
- Carcinoma of breast
- Disease of liver
- Neoplasm of liver
- Porphyria
Contraindicated
- Acute myocardial infarction
- Bed-ridden
- Cerebrovascular accident
- Coronary artery disease
- Deep venous thrombosis
- Migraine
- Obesity
- Predisposition to thrombosis
- Pulmonary thromboembolism
- Retinal thrombosis
- Thromboembolic disorder
- Thrombophlebitis
- Tobacco smoker
Severe
Moderate
- Depression
- Diabetes mellitus
- Edema
- Hyperlipidemia
- Hypertension
PROGESTERONE (progesterone)
- Abnormal uterine bleeding due to hormonal imbalance
- Amenorrhea secondary to ovarian dysfunction
- Abnormal vaginal bleeding
- Irregular menstrual periods
- Acute abdominal pain
- Appetite changes
- Edema
- General weakness
- Headache disorder
- Injection site sequelae
- Mastalgia
- Vaginitis
- Weight gain
- Weight loss
More Frequent
Severe
Less Severe
- Hypersensitivity drug reaction
- Mood changes
- Acne vulgaris
- Amenorrhea
- Back pain
- Cervical discharge
- Diarrhea
- Dizziness
- Drowsy
- Dysmenorrhea
- Erosion of cervix
- Flu-like symptoms
- Menstrual disorder
- Nausea
- Pharyngitis
- Pruritus of skin
- Vaginal discharge
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Angioedema
- Cerebrovascular accident
- Depression
- Eosinophilic pneumonia
- Gallbladder obstruction
- Hepatitis
- Jaundice
- Migration of implant
- Obstructive hyperbilirubinemia
- Ovarian cyst
- Pulmonary thromboembolism
- Skin rash
- Thrombophlebitis
- Thrombotic disorder
Less Severe
- Alopecia
- Body fluid retention
- Chest discomfort
- Chloasma
- Constipation
- Dysuria
- Fatigue
- Fever
- Flatulence
- Flushing
- Galactorrhea not associated with childbirth
- Genital organ pruritus
- Gynecomastia
- Hirsutism
- Insomnia
- Libido changes
- Migraine
- Musculoskeletal pain
- Myalgias
- Nervousness
- Pain
- Paresthesia
- Rhinitis
- Seborrhea
- Sinusitis
- Urinary tract infection
- Urticaria
- Visual changes
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Progesterone
Safety and efficacy in pediatrics have not been established.
- 1 Day – 18 Years
- Safety and efficacy in pediatrics have not been established.
Progesterone
- Severity Level:
B
- Additional Notes: Insufficient human data; animal data do not suggest dev tox
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Progesterone
Data suggest low amount excreted with no adverse effects on infants
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Data suggest low amount excreted with no adverse effects on infants |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Abnormal uterine bleeding due to hormonal imbalance | |
| N92.4 | Excessive bleeding in the premenopausal period |
| N92.5 | Other specified irregular menstruation |
| N92.6 | Irregular menstruation, unspecified |
| N93.8 | Other specified abnormal uterine and vaginal bleeding |
| N93.9 | Abnormal uterine and vaginal bleeding, unspecified |
| N95.0 | Postmenopausal bleeding |
| Amenorrhea secondary to ovarian dysfunction | |
| E28.8 | Other ovarian dysfunction |
| E28.9 | Ovarian dysfunction, unspecified |
| N91.0 | Primary amenorrhea |
| N91.1 | Secondary amenorrhea |
| N91.2 | Amenorrhea, unspecified |
| 0-9 | A-Z |
|---|---|
| E28.8 | Other ovarian dysfunction |
| E28.9 | Ovarian dysfunction, unspecified |
| N91.0 | Primary amenorrhea |
| N91.1 | Secondary amenorrhea |
| N91.2 | Amenorrhea, unspecified |
| N92.4 | Excessive bleeding in the premenopausal period |
| N92.5 | Other specified irregular menstruation |
| N92.6 | Irregular menstruation, unspecified |
| N93.8 | Other specified abnormal uterine and vaginal bleeding |
| N93.9 | Abnormal uterine and vaginal bleeding, unspecified |
| N95.0 | Postmenopausal bleeding |
Formulary Reference Tool